Clinical impact of term-equivalent magnetic resonance imaging in extremely low-birth-weight infants at a regional NICU
Abstract
Objective To evaluate the clinical impact of routine term-equivalent magnetic resonance imaging (TE-MRI) for extremely low-birth-weight infants at a regional neonatal intensive care unit.Study design This is a single-center retrospective study evaluating preterm survivors who underwent TE-MRI. MRI abnormalities were compared between infants with and without cranial ultrasonography (CUS) abnormalities. Cost analysis comparing imaging modalities was also performed.Results TE-MRI use increased from 17% in 2006 to 76% in 2010. MRI detected new findings in nearly half of infants, whether or not they had known ultrasound abnormalities. MRI detected more cerebellar (18% vs 6%, P=0.04) and moderate white matter injury (12% vs 7%, P<0.001), and altered simulated neurological prognosis across developmental domains. The cost of TE-MRI was $1600, which was comparable to serial CUSs.Conclusion TE-MRI detects new abnormalities and impacts developmental prognosis in the extremely low birth weight, which supports its use despite the added financial cost.
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MRI is essential in the NICU because of its ability to deliver precise assessment of white matter, gray matter, and posterior fossa abnormalities with functional capabilities that exceed those of ultrasound.
“Magnetic resonance imaging (MRI) is essential in the NICU because of its ability to deliver precise assessment ofwhitematter, graymatter, and posterior fossa abnormalities with functional capabilities that exceed those of ultrasound (23 , 24).”
From Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care (2019) · cites this paper as [24]
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- Authors
- Melbourne, L., Chang, T., Murnick, J., Zaniletti, I., Glass, P., & Massaro, A. N.
- Affiliations
- Children's National (US)
- Children's Hospital Association (US)
- Corresponding author
- Massaro, A N
- Venue
- Journal of Perinatology
- Published
- 2016-07-28
- Volume
- 36
- Issue
- 11
- Pages
- 985-989
- ISSN
- 0743-8346 (ISSN-L)
- 1476-5543
- OpenAlex
- W2507023716
- Cited by
- 13
- References
- 26
- Citations by year
- 2024: 3 · 2022: 2 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 2
- FWCI
- 1.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Perinatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and fetal brain pathology
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Fetal and Pediatric Neurological Disorders
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Keywords
- extremely low birth weight infants, neonatal brain injury, cranial ultrasound, white matter injury, cerebellar lesions, neurodevelopmental prognosis, neonatal intensive care
- MeSH terms
- Brain, Echoencephalography, Female, Humans, Infant, Newborn, Infant, Premature, Diseases, Intensive Care Units, Neonatal, Magnetic Resonance Imaging, Male, Retrospective Studies, Ultrasonography, Case-Control Studies, Statistics, Nonparametric, Infant, Extremely Low Birth Weight, Infant, Extremely Premature
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