Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

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Items 101–200 of 999

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  6. Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM)
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  72. Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia
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  75. Epigenetics in the hematologic malignancies
    Chun Yew Fong, Jessica Morison, Mark A. Dawson · 2014 · Haematologica
  76. Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice
    Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato et al. · 2017 · Blood
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  78. Molecular impact of mutations in RNA splicing factors in cancer
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  79. Gene expression and risk of leukemic transformation in myelodysplasia
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  80. High-throughput sequencing for noninvasive disease detection in hematologic malignancies
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  81. A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma
    Niccolò Bolli, Y Li, Vijitha Sathiaseelan, Keiran M. Raine, David Jones, Peter S. Ganly, Federica Cocito, Graham R. Bignell, M A Chapman, Adam Samuel Sperling et al. · 2016 · Blood Cancer Journal
  82. SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment
    Syed A. Mian, Kevin Rouault‐Pierre, Alexander Smith, Thomas Seidl, Irene Pizzitola, Aytug Kizilors, Austin Gladston Kulasekararaj, Dominique A. Bonnet, Ghulam Jeelani Mufti · 2015 · Nature Communications
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  84. Cohesin Mutations in Cancer
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  85. SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells
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  86. Targeting splicing abnormalities in cancer
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  87. Baseline and serial molecular profiling predicts outcomes with hypomethylating agents in myelodysplastic syndromes
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  89. The genetic and molecular pathogenesis of myelodysplastic syndromes
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    Deli Hong, Andrew J. Fritz, Jonathan A. R. Gordon, Coralee E. Tye, Joseph R. Boyd, Kirsten M. Tracy, Seth E. Frietze, Frances E. Carr, Jeffrey A. Nickerson, André J. van Wijnen et al. · 2018 · Journal of Cellular Physiology
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    Chunkang Chang, Youshan Zhao, Feng Xu, Juan Guo, Zheng Zhang, Qi He, Dong Wu, Lingyun Wu, Jiying Su, Lu‐Xi Song et al. · 2016 · British Journal of Haematology
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    Atsushi Narita, Hideki Muramatsu, Y. Sekiya, Yusuke Okuno, Hiroshi Sakaguchi, N. Nishio, N. Yoshida, Xinan Wang, Yinyan Xu, Nozomu Kawashima et al. · 2015 · Haematologica
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  96. The 2016 revision to the World Health Organization classification of myelodysplastic syndromes
    Ming Hong, Guangsheng He · 2017 · Journal of Translational Internal Medicine
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  98. N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
    Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang et al. · 2019 · Nature Communications
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  100. DNA methylation and hydroxymethylation in hematologic differentiation and transformation
    Myunggon Ko, Jungeun An, Anjana Rao · 2015 · Current Opinion in Cell Biology