Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia
the International Schizophrenia Consortium, Lips, E S, Cornelisse, L N, Toonen, R F, Min, J L, Hultman, C M, Holmans, P A, O'Donovan, M C +6 more·2012·Molecular Psychiatry
Cited by (167)
Items 101–167 of 167
- Resequencing Three Candidate Genes for Major Depressive Disorder in a Dutch CohortEva C. Verbeek, Marianna R. Bevova, Zoltán Bochdanovits, Patrizia Rizzu, Ingrid M. C. Bakker, Tiny Uithuisje, Eco J. C. de Geus, Johannes H. Smit, Brenda W.J.H. Penninx, Dorret Irene Boomsma et al. · 2013 · PLoS ONE
- Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable miceYurie Matsumoto, Minae Niwa, Akihiro Mouri, Yukihiro Noda, Takeshi Fukushima, Norio Ozaki, Toshitaka Nabeshima · 2017 · Psychopharmacology
- Association Studies of HSPA1A and HSPA1L Gene Polymorphisms With SchizophreniaMałgorzata Kowalczyk, Krzysztof Artur Kucia, Aleksander Jerzy Owczarek, Renata Suchanek-Raif, Wojciech Merk, Monika Paul-Samojedny, Jan Kowalski · 2018 · Archives of Medical Research
- Schizophrenia at a Genetics Crossroads: Where to Now?Aiden Peter Corvin · 2013 · Schizophrenia Bulletin
- A missense mutation in the ITGA8 gene, a cell adhesion molecule gene, is associated with schizophrenia in Japanese female patientsIrwan Supriyanto, Yuichiro Watanabe, Kentaro Mouri, Kyoichi Shiroiwa, Woraphat Ratta‐apha, Masakuni Yoshida, Genki Tamiya, Toru Sasada, Noriomi Eguchi, Kenji Okazaki et al. · 2012 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelingTuomo Mäki‐Marttunen, Kim T. Blackwell, Ibrahim A. Akkouh, Alexey A. Shadrin, Mathias Valstad, Torbjørn Elvsåshagen, Marja‐Leena Linne, Srdjan Djurovic, Gaute T. Einevoll, Ole A. Andreassen · 2024 · Proceedings of the National Academy of Sciences
- JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex TraitsEsther H. Lips, Maarten Kooyman, Christiaan de Leeuw, Daniëlle Posthuma · 2015 · Genes
- Genomic Analyses of Visual Cognition: Perceptual Rivalry and Top-Down ControlBiqing Chen, Zijian Zhu, Ren Na, Fang Wan, Wenxia Zhang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen et al. · 2018 · Journal of Neuroscience
- Improved Functional Enrichment Analysis of Biological Networks using Scalable Modularity Based ClusteringC. Mclean · 2016 · Journal of Proteomics & Bioinformatics
- Strength of functional signature correlates with effect size in autismSara Ballouz, Jesse Gillis · 2017 · Genome Medicine
- Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophreniaMaxime Veleanu, Beetsi Urrieta-Chávez, Séverine M. Sigoillot, Maëla A. Paul, Alessia Usardi, Keerthana Iyer, Marine Delagrange, Joseph Doyle, Nathaniel Heintz, Carine Bécamel et al. · 2022 · Proceedings of the National Academy of Sciences
- RETRACTED: Identification of gene ontologies linked to prefrontal–hippocampal functional coupling in the human brainLuanna Dixson, Henrik Walter, Michael Schneider, Susanne Erk, Axel Schäfer, Leila Haddad, Oliver Grimm, Manuel Mattheisen, Markus Maria Nöthen, Sven Cichon et al. · 2014 · Proceedings of the National Academy of Sciences · Retracted
- Generation and initial characterization of mice lacking full‐length BAI3 (ADGRB3) expressionFu Hung Shiu, Jennifer C. Wong, Debanjan Bhattacharya, Yuki Kuranaga, Rashed Rezwan Parag, Haifa A. Alsharif, Sushant Bhatnagar, Erwin G. Van Meir, Andrew Escayg · 2023 · Basic & Clinical Pharmacology & Toxicology
- Overlapping Etiology of Neurodevelopmental DisordersEric Kelleher, Aiden Peter Corvin · 2015 · Wiley eBooks
- Searching for ancient balanced polymorphisms shared between Neanderthals and Modern HumansLucas Henriques Viscardi, Vanessa Rodrigues Paixão‐Côrtes, David Comas, Francisco M. Salzano, Diego Luiz Rovaris, Claiton H.D. Bau, Carlos Eduardo G. Amorim, María Cátira Bortolini · 2018 · Genetics and Molecular Biology
- A Population-Based Imaging Genetics Study of Inattention/Hyperactivity: Basal Ganglia and Genetic PathwaysSabine E. Mous, Anke R. Hammerschlag, Tinca J. C. Polderman, Frank C. Verhulst, Henning W. Tiemeier, Aad van der Lugt, Vincent W. V. Jaddoe, Albert Hofman D, Tonya J.H. White, Danielle Posthuma B · 2015 · Journal of the American Academy of Child & Adolescent Psychiatry
- The Genetics of MDD – A Review of Challenges and OpportunitiesMarianna R Peter Heutink · 2014 · Journal of Depression & Anxiety
- Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disordersBenxia Hu, Hyejung Won, Won Mah, Royce Park, Bibi S. Kassim, Keeley Spiess, Alexey Kozlenkov, Cheynna Crowley, Sirisha Pochareddy, Yun Li et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- The Contribution of Mosaic Chromosomal Alterations to SchizophreniaKaihui Chang, Xuemin Jian, Chuanhong Wu, Chengwen Gao, Yafang Li, Jianhua Chen, Baiqiang Xue, Yonghe Ding, Lixia Peng, Baokun Wang et al. · 2024 · Biological Psychiatry
- Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia SusceptibilityTsung‐Ming Hu, Ying-Chieh Wang, Chia‐Liang Wu, Shih-Hsin Hsu, Hsin-Yao Tsai, Min-Chih Cheng · 2020 · Frontiers in Genetics
- Functional Gene-Set Analysis Does Not Support a Major Role for Synaptic Function in Attention Deficit/Hyperactivity Disorder (ADHD)Anke R. Hammerschlag, Tinca J. C. Polderman, Christiaan de Leeuw, Henning W. Tiemeier, Tonya J.H. White, August Benjamin Smit, Matthijs Verhage, Daniëlle Posthuma · 2014 · Genes
- A Longitudinal Model of Human Neuronal Differentiation for Functional Investigation of Schizophrenia Polygenic RiskAnil P. S. Ori, Merel H.M. Bot, Remco T. Molenhuis, Loes M. Olde Loohuis, Roel A. Ophoff · 2018 · Biological Psychiatry
- Beyond main effects of gene‐sets: harsh parenting moderates the association between a dopamine gene‐set and child externalizing behaviorDafna A. Windhorst, Viara R. Mileva‐Seitz, Ralph C. A. Rippe, Henning W. Tiemeier, Vincent W. V. Jaddoe, Frank C. Verhulst, Marinus H. van IJzendoorn, Marian J. Bakermans‐Kranenburg · 2016 · Brain and Behavior
- Haloperidol rescues the schizophrenia-like phenotype in adulthood after rotenone administration in neonatal ratsThiago Garcia Varga, Juan Guilherme de Toledo Simões, Amanda Siena, Elisandra Henrique, Regina Cláudia Barbosa da Silva, Vinícius S. Bioni, Aline Camargo Ramos, Tatiana Rosado Rosenstock · 2021 · Psychopharmacology
- Tauopathies: The Role of Tau in Cellular Crosstalk and Synaptic DysfunctionsMarta Caamaño-Moreno, Ricardo Gargini · 2022 · Neuroscience
- Cortical and thalamic modulation of auditory gating in the posterior parietal cortex of awake miceShuai Wang, Zijie Li, Xuejiao Wang, Jinhong Li, Xueru Wang, Jingyu Chen, Yingna Li, Changming Wang, Ling Qin · 2023 · Cerebral Cortex
- Calcium Imaging in Drug Discovery for Psychiatric DisordersSaurav Seshadri, Daniel J. Hoeppner, Katsunori Tajinda · 2020 · Frontiers in Psychiatry
- Gene prioritization in GWAS loci using multimodal evidenceMarijn Schipper, Christiaan de Leeuw, Bernardo de A.P.C. Maciel, Douglas P. Wightman, Nikki Hubers, Dorret Irene Boomsma, Michael C. O’Donovan, Danielle Posthuma B · 2023 · medRxiv
- Breaking Free from the Chains of Pathway Annotation: de Novo Pathway Discovery for the Analysis of Disease ProcessesBenjamin C. Lehne, Thomas Schlitt · 2012 · Pharmacogenomics
- Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injuryJuliette Van Steenwinckel, Anne‐Laure Schang, Michelle L. Krishnan, Vincent Degos, Andrée Delahaye‐Duriez, Cindy Bokobza, Franck Verdonk, Amélie Montané, Stéphanie Sigaut, Olivier Hennebert et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- The NIMH Research Domain Criteria ProjectBruce N. Cuthbert · 2016 · Elsevier eBooks
- GRPa‐PRS: A risk stratification method to identify genetically‐regulated pathways in polygenic diseasesXiaoyang Li, Brisa Simões Fernandes, Andi Liu, Jingchun Chen, Xiangning Chen, Zhongming Zhao, Yulin Dai · 2025 · Alzheimer s & Dementia
- Cognitive and Physical AgingChandra A. Reynolds, Deborah Finkel · 2015 · Elsevier eBooks
- Pathway‐Informed Machine Learning Identifies Genetic Predictors of High‐Dose Methotrexate‐Induced Mucositis in Pediatric Acute Lymphoblastic LeukemiaXiao Yu Cindy Zhang, Erika N. Scott, Hedy Maagdenberg, Alice Man, Kathy H. Li, Shahrad Rod Rassekh, Bruce Carleton, Colin J. Ross, Wyeth W. Wasserman, Catrina M. Loucks · 2025 · Clinical Pharmacology & Therapeutics
- Molecular signatures and emerging therapeutic targets in schizophrenia: A biomarker-centric perspective in psychiatric disordersMohammed Ageeli Hakami · 2025 · Schizophrenia Research
- The relationship between schizophrenia polygenic scores, blood-based proteins and psychosis diagnosis in the UK BiobankKimberley Marie Kendall, Sophie E. Legge, Eilidh Fenner, Peter Holmans, James TR Walters · 2026 · Schizophrenia
- Sequencing and expression analyses of the synaptic lipid raft adapter gene PAG1 in schizophreniaShabeesh Balan, Yoshimi Iwayama, Kazuo Yamada, Tomoko Toyota, Tetsuo Ohnishi, Manabu Toyoshima, Chie Shimamoto, Masayuki Ide, Yasuhide Iwata, Katsuaki Suzuki et al. · 2014 · Journal of Neural Transmission
- Cognitive domains function complementation by NTNG gene paralogsPavel Prosselkov, Denis Polygalov, Qi Zhang, Thomas John McHugh, Shigeyoshi Itohara · 2016 · Biomedical Genetics and Genomics
- BioNAR: an integrated biological network analysis package in bioconductorC. Mclean, Anatoly Sorokin, T. Ian Simpson, J. Douglas Armstrong, Oksana Sorokina · 2023 · Bioinformatics Advances
- Proteomic analyses of limbic regions in neonatal male, female and androgen receptor knockout miceAnna Zettergren, Sara A. Karlsson, Erik Studer, Anna Sarvimäki, Petronella Kettunen, Annika Thorsell, Carina Sihlbom, Lars Westberg · 2017 · BMC Neuroscience
- Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognitionGuillaume Dumas, Simon Malesys, Thomas Bourgeron · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Integrative Analysis Identified Key Schizophrenia Risk Factors from an Abnormal Behavior Mouse Gene SetMiao Chen, Weidi Wang, Weichen Song, Wei Qian, Guan Ning Lin · 2021 · Life
- Synaptic proteins expressed by oligodendrocytes mediate CNS myelinationAlexandria Hughes, Bruce Appel · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Cell group analysis reveals changes in upper-layer neurons associated with schizophreniaRujia Dai, Lulu Chen, Sihan Liu, Chiung-Ting Wu, Yu Chen, Yi Wei Jiang, Rujia Dai, Qihang Wang, Richard F. Kopp, Guoqiang Yu et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Oscillatory-Quality of sleep spindles: from properties to functionC. Blanco-Duque, Suraya A. Bond, L. Krone, Jean-Philippe Dufour, Edward C P Gillen, M. Kahn, R. Purple, D. Bannerman, E. Mann, P. Achermann et al. · 2023 · bioRxiv
- The expanding roles of adhesion GPCRs in neural circuit assemblyShane Watson, Richard C. Sando · 2026 · Molecules and Cells
- Computational Pipeline for Analysis of Biomedical Networks with BioNARC. Mclean, Anatoly Sorokin, J. Douglas Armstrong, Oksana Sorokina · 2023 · Current Protocols
- Genetic architecture and behavioral analysis of attention and impulsivityMaarten Loos · 2012 · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
- The aging synapse: Synaptic proteome changes in mouse models of agingMarlene J. Végh · 2012 · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
- A longitudinal model of human neuronal differentiation for functional investigation of schizophrenia polygenic riskAnil P. S. Ori, Merel H.M. Bot, Remco T. Molenhuis, Loes M. Olde Loohuis, Roel A. Ophoff · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- The function of TCF4 in Pitt-Hopkins syndrome and schizophreniaMarc P. Forrest · 2013 · ORCA Online Research @Cardiff (Cardiff University)
- Recent Updates in Schizophrenia GeneticsHee Jeong Jeong, Byung Dae Lee, Je‐Min Park, Young Min Lee, Eunsoo Moon · 2013 · Korean Journal of Schizophrenia Research
- SchizophreniaAiden Peter Corvin · 2016 · Elsevier eBooks
- Integrating Genome-Wide Association and Blood Genomic Profiling Data to Characterise Migraine Risk LociZachary F. Gerring · 2017 · Queensland University of Technology
- Sequencing and expression analyses of the synaptic lipid raft adapter gene PAG1 in schizophrenia Shabeesh BalanYoshimi IwayamaKazuo YamadaTomoko ToyotaTetsuo Ohnishi • Manabu ToyoshimaChie ShimamotoMasayuki IdeYasuhide IwataKatsuaki Suzuki • Mitsuru KikuchiTasuku HashimotoNobuhisa KanaharaTakeo YoshikawaMotoko MaekawaSpringer-Verlag Wien · 2015
- Neuronal and microglial interactions with oligodendrocytes regulate myelin sheath formation and eliminationAlexandria Hughes · 2020
- Statistical approaches of gene set analysis with quantitative trait loci for high-throughput genomic studies.Samarendra Das · 2020
- Analysis of gene systems across brain disordersSnow Bach · 2021 · Dublin City University Open Access Institutional Repository (Dublin City University)
- Faculty Opinions recommendation of SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.Barry Smith · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modellingTuomo Mäki‐Marttunen, Kim T. Blackwell, Ibrahim A. Akkouh, Alexey A. Shadrin, Mathias Valstad, Tobjørn Elvsåashagen, Marja‐Leena Linne, Srdjan Djurovic, Gaute T. Einevoll, Ole A. Andreassen · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic RiskRui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S. Sutcliffe, Yi Wei Jiang, Ying Ji, Chunyu Liu et al. · 2025 · Advanced Science
- Cell‐Specific Functions of the BAI / ADGRB Subfamily of Adhesion G‐Protein Coupled ReceptorsHaifa A. Alsharif, Sushant Bhatnagar · 2025 · Comprehensive physiology
- Edge-centric functional network analyses and their associated genetic mechanisms in patients with first-episode schizophreniaYafei Kang, Jiayi Yang, Runzhu Zhang, Hongbo Guo, Feng Liu, Youming Zhang, Gang Wang · 2026 · Behavioural Brain Research
- Neurodevelopmental impact of perinatal inflammation : targets for neuroprotection?Cindy Bokobza · 2019 · theses.fr (ABES)
- Mapping topological abnormalities in cortical similarity networks to schizophrenia-associated gene expressionSung Woo Joo, JungSun Lee · 2026 · Dialogues in Clinical Neuroscience
- Genetic basis of phase amplitude coupling entrained by working memoryAnahita Nazari, Stefan Treue, Moein Esghaei · 2026 · Scientific Reports
- Trans-synaptic interaction of orphan GPCR GPR88 and adhesion GPCR BAI3 through C1ql1 maintains synapse integrityYing Han, Qingbiao Meng, Xuan Li, Qin Huang, Liming Qin, Liangyu Liao, Ke-Ke Xing, Jie Cheng, Lulu Guo, Chao Zhang et al. · 2026 · Science Advances