A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder

Milak, M S, Proper, C J, Mulhern, S T, Parter, A L, Kegeles, L S, Ogden, R T, Mao, X, Rodriguez, C I +6 more·2016·Molecular Psychiatry

Cited by (144)

Items 101–144 of 144

  1. Altered Cortical Gamma-Amino Butyric Acid in Female Veterans With Suicidal Behavior: Sex Differences and Clinical Correlates
    Andrew P. Prescot, Chandni S. Sheth, Margaret D. Legarreta, Perry Franklin Renshaw, Erin McGlade, Deborah A Yurgelun-Todd · 2018 · Chronic Stress
  2. Effects of common anesthetic agents on [18F]flumazenil binding to the GABAA receptor
    Mikael Palner, Corinne Beinat, Samuel D. Banister, Francesca Zanderigo, Jun Hyung Park, Bin Shen, Trine Hjørnevik, Jae Ho Jung, Byung Chul Lee, Sang Eun Kim et al. · 2016 · EJNMMI Research
  3. Region- and time- specific effects of ketamine on cerebral blood flow: a randomized controlled trial
    Matti Gärtner, Anne Weigand, Marvin Sören Meiering, David Weigner, Luisa Carstens, Christian Keicher, Rita Hertrampf, Christian F. Beckmann, Maarten Mennes, Andreas Wunder et al. · 2023 · Neuropsychopharmacology
  4. Effect of Ketamine on Human Neurochemistry in Posterior Cingulate Cortex: A Pilot Magnetic Resonance Spectroscopy Study at 3 Tesla
    Petr Bednařík, Benjamin Spurny‐Dworak, L. Silberbauer, Alena Svátková, Patricia Anna Handschuh, Birgit Reiter, Melisande E. Konadu, Thomas Stimpfl, Marie Spies, Wolfgang Bogner et al. · 2021 · Frontiers in Neuroscience
  5. Glutamate Chemical Exchange Saturation Transfer ( GluCEST ) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model
    Hao Li, Xunrong Luo, Kai Qi, Yijie Lv, Junnan Kan, Changfeng Yang, Xiaoqian Lin, Jin Tao, Wei Zhang, Yan Liu et al. · 2023 · Journal of Magnetic Resonance Imaging
  6. Clinical neuroimaging markers of response to treatment in mood disorders
    Michele Porcu, Antonella Balestrieri, Paolo Siotto, Pierleone Lucatelli, Michele Anzidei, Jasjit S. Suri, Fulvio Zaccagna, Giovanni Maria Argiolas, Luca Saba · 2016 · Neuroscience Letters
  7. Functional connectivity of the amygdala subregions and the antidepressant effects of repeated ketamine infusions in major depressive disorder
    Haiyan Liu, Chengyu Wang, Xiaofeng Lan, Weicheng Li, Fan Zhang, Zhibo Hu, Yanxiang Ye, Yuping Ning, Yanling Zhou · 2024 · European Psychiatry
  8. The Basic and Clinical Pharmacology of Ketamine
    Elizabeth Wolf Fourcade, Kyle A. B. Lapidus · 2016 · Springer eBooks
  9. Update on Ketamine
    Jon Zhou, Perry Hamilton, Stephen M. Macres, M Santos Pena, Schirin Tang · 2020 · Advances in Anesthesia
  10. Single-Molecule Detection of Acetylcholine by Translating the Neuronal Signal to a Single Distinct Electronic Peak
    Xinyue Dai, Kai Le, Fenglong Wang, Rubin Wei, Jiurong Liu, Yanyan Jiang, Hui Li · 2020 · ACS Applied Bio Materials
  11. Glutamate plus glutamine to GABA ratio as a predictor of ketamine response in treatment-resistant depression: A double-blind, randomized, open-label extension study
    Yohei Ohtani, Hideaki Tani, Shiori Honda, Kie Nomoto‐Takahashi, Taisuke Yatomi, Kengo Yonezawa, Sota Tomiyama, Nobuhiro Nagai, Keisuke Kusudo, Sotaro Moriyama et al. · 2025 · Journal of Affective Disorders
  12. Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits
    Meixiang Huang, Yannan Li, Ajit G. Thomas, Anjali Sharma, Wathsala Liyanage, Tomáš Tichý, Lukáš Tenora, Yu Su, Jisu Ha, Niyada Hin et al. · 2025 · Neurotherapeutics
  13. Psychedelics and ketamine/esketamine in depressive disorders: biological mechanisms and associated neuroimaging and clinical changes
    Giacomo d’Andrea, Stefania Chiappini, Laura Ciavoni, Rolando Tucci, Fabrizio Martino, Francesco Maria Semeraro, Daniele Di Battista, Alessio Mosca, Andrea Miuli, Francesco Di Carlo et al. · 2025 · Translational Psychiatry
  14. Subanesthetic ketamine alters EEG signal complexity: Implications for treatment stratification in depression
    Weng-Lam Chan, Sebastian Olbrich, Xinwen Jiang, Haoyun Zhang, Cheng-Teng Ip, Martin Brunovský · 2025 · Journal of Affective Disorders
  15. Higher glutamatergic activity in the medial prefrontal cortex in chronic ketamine users
    Qiuxia Wu, Jinsong Tang, Chang Qi, An Xie, Jianbin Liu, Joseph O’Neill, Tieqiao Liu, Wei Hao, Yanhui Liao · 2022 · Journal of Psychiatry and Neuroscience
  16. Ketamine administration in idiopathic epileptic and healthy control dogs: Can we detect differences in brain metabolite response with spectroscopy?
    Manuela Wieser, Katrin Melanie Beckmann, Annette P. N. Kutter, Nico Mauri, Henning Richter, Niklaus Zoelch, Rima Nadine Bektas · 2023 · Frontiers in Veterinary Science
  17. Ketamine’s Mechanism of Rapid Antidepressant Activity: Evidence Gleaned from Clinical Studies
    Lynnette A. Averill, James W. Murrough, Chadi G. Abdallah · 2016 · Springer eBooks
  18. Pharmacotherapy for Cocaine Use Disorders
    Boris B. Quednow, Etna Engeli, Marcus Herdener · 2022 · Springer eBooks
  19. A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized 1H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator
    Corin O. Miller, Liza T. Gantert, Stephen F. Previs, Ying Chen, Kenneth D. Anderson, Justina M. Thomas, Gerard Sanacora, Jason M. Uslaner, Douglas L. Rothman, Graeme F. Mason · 2020 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
  20. Examining the relationship between gray matter volume and a continuous measure of bipolarity in unmedicated unipolar and bipolar depression
    Reuben Heyman-Kantor, Mina Rizk, M. Elizabeth Sublette, Harry Rubin‐Falcone, Yashar Yousefzadeh-fard, Ainsley K. Burke, María A. Oquendo, Gregory M. Sullivan, Matthew S. Milak, Francesca Zanderigo et al. · 2020 · Journal of Affective Disorders
  21. Kynurenine Metabolism is Associated with Antidepressant Response to Selective Serotonin Reuptake Inhibitors
    Ryan Rampersaud, Klara Suneson, Gwyneth W. Y. Wu, Victor I. Reus, Daniel Lindqvist, Tiffany Cheing Ho, Dieter Johannes Meyerhoff, Michael R. Irwin, Owen M. Wolkowitz, Synthia H. Mellon et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Concerted elevations of cortical and striatal glutamate and GABA in antipsychotic-free individuals at clinical high-risk for psychosis
    Ragy R. Girgis, Camilo de la Fuente‐Sandoval, Roberto Lewis‐Fernández, Francisco Reyes-Madrigal, Melanie M. Wall, Jialiang Hua, Xiangling Mao, Melanie Malacara, Lawrence S. Kegeles, Dikoma C. Shungu · 2025 · Neuropsychopharmacology
  23. Modulation of Magnetic Resonance Spectroscopy Levels of Glutamate and GABA by Ketamine in Treatment‐Resistant Depression
    Stephanie N. Njau, Artemis Zavaliangos‐Petropulu, Shantanu H. Joshi, John O. Brooks, Joseph O'Neill, Woods P. Roger, Vera Norris, Randall T. Espinoza, Katherine L. Narr · 2025 · Journal of Neuroscience Research
  24. Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stress and Stress-Related Disorders
    Laurence D. Coutellier, Laura Musazzi, Zoran M. Pavlovic · 2022 · Springer eBooks
  25. Brain Glutamate Dynamics Predict Positive Agency in Healthy Women: Insights from Combined Application of Pharmacological Challenge, Comprehensive Affective Assessment, and Magnetic Resonance Spectroscopy
    Tara L. White, Meghan A. Gonsalves, Ashley D. Harris, Edward G. Walsh, Hannah E. Joyce · 2024 · ACS Chemical Neuroscience
  26. Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience
    Devin Rocks, Conor M. Liston · 2024 · Neuroscience Research
  27. Advancing cancer neuroscience through stress modulation: Interdisciplinary potential of psilocybin and ketamine
    Alan C. Courtes, Blake Myers, Noah Daly, Greg Jones, Jair C. Soares, Carlos A. Zarate, Rodrigo Machado‐Vieira · 2026 · General Hospital Psychiatry
  28. Astrocytes in the Circadian System: A Promising Target for Mood Disorder Interventions
    Peijie Liu, Hongguo Li, Yuchen Zhu, Siqi Song, Liang Kang, Yushi Hu · 2026 · Journal of Integrative Neuroscience
  29. Pharmacotherapy for Cocaine Use Disorders
    Boris B. Quednow, Etna Engeli, Marcus Herdener · 2021 · Springer eBooks
  30. Activation of the TrkB Neurotrophin Receptor by Antidepressant Drugs
    Hanna Antila · 2016 · Työväentutkimus Vuosikirja
  31. Indexing Cortical Reactivity with TMS in Major Depressive Disorder and Response to Therapeutic Brain Stimulation
    Daphne Voineskos · 2019 · TSpace (University of Toronto)
  32. Neurotransmitters & Networks
    van Veenendaal · 2017
  33. Variation in in vivo prefrontal GABA, glutamate and glutamine – effects of reproductive factors, cortisol and major depressive disorder
    Paramjit P. Bhardwaj · 2017 · ERA: Education and Research Archive (University of Alberta)
  34. Ketamine's potential mechanism of action for rapid antidepressive effects – a focus on neuroplasticity
    Melody J.Y. Kang · 2020 · Elsevier eBooks
  35. Faculty Opinions recommendation of Prefrontal connectivity and glutamate transmission: relevance to depression pathophysiology and ketamine treatment.
    Hanns Möhler · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  36. Brain Glutamate Dynamics Predict Positive Agency in Healthy Women
    Tara L. White, Meghan A. Gonsalves, Ashley D. Harris, Edward G. Walsh, Hannah E. Joyce · 2023 · Research Square
  37. Dynamic Processes Induced by Ketamine and Their Potential for Augmented Treatment Strategies in Neuropsychiatric Disorders
    Meng Li, Zümrüt Duygu Şen, Lena Vera Danyeli, Nooshin Javaheripour, Martin Walter · 2025 · Neuromethods
  38. Glutamine Metabolite Ratios are Related to Thwarted Belongingness and Perceived Burdensomeness: Preliminary Evidence from a Veteran Sample with and Without History of Suicidal Ideation
    James R. Yancey, Punitha Subramaniam, Jiyoung Ma, Chelsea N. Carson, Keenan E. Roberts, Erin McGlade, Perry Franklin Renshaw, Deborah A Yurgelun-Todd · 2025 · Chronic Stress
  39. Research progresses on molecular mechanisms and analytical technologies of depression
    TongTong YANG, Huajie Sui, Tenggao Zhu, Zhencai Chen, Ke Peng, Guobing Wang, Huanwen Chen · 2026 · Scientia Sinica Vitae
  40. Ketamine-induced changes in accumbal glutamate and their association with altered states of consciousness
    Ladina P Gubser, Anna Trippel, Niklaus Zoelch, Etna Engeli, Marcus Herdener · 2026 · Brain Research Bulletin
  41. Nouvelles perspectives concernant le traitement du Syndrome Douloureux Régional Complexe par la kétamine
    Marc Sorel · 2017
  42. Ketamine preserves perineuronal nets in chronic stressed mice brain through the inhibition of microglia activation
    Jingwen Yang, Ting Huang, Meng Wang, Xu Yingrui, Li Xuan, Changqi Li, Wenyu Cao, He Liyan, Hua mao Zhou · 2026 · IBRO Neuroscience Reports
  43. Convergent neuroimmune signaling underlying rapid antidepressant response to ketamine and psychedelics
    Gregory H. Jones, Jessica R. Gilbert, Jenessa N. Johnston, Nirmala Akula, Anton Schulmann, Miranda H. Arakelian, Shiyong Peng, Peixiong Yuan, Ewurakua A. Winful, Mani Yavi et al. · 2026 · Molecular Psychiatry
  44. Modulation of GABA and glutamate by ketamine in depression: A systematic review and meta-analysis of magnetic resonance spectroscopy studies
    Balwinder Singh, Hossam M. Ali, Alessandro Miola, Nicolás A. Núñez, Manoela V. Fogaça, Luke A. Jelen, Larry J. Prokop, Gerard Sanacora, Carlos A. Zarate, Mark A. Frye et al. · 2026 · Neuropsychopharmacology