Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability

Karikó, Katalin, Muramatsu, Hiromi, Welsh, Frank A, Ludwig, János, Kato, Hiroki, Akira, Shizuo, Weissman, Drew·2008·Molecular Therapy

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Items 601–700 of 1,003

  1. Development of nucleic acid medicines based on chemical technology
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  5. Personalized mRNA vaccines in glioblastoma therapy: from rational design to clinical trials
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  6. Single-dose mRNA therapy via biomaterial-mediated sequestration of overexpressed proteins
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  7. In Gratitude for mRNA Vaccines
    Lynda M. Stuart · 2021 · New England Journal of Medicine
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  14. mRNA and Adenoviral Vector Vaccine Platforms Utilized in COVID-19 Vaccines: Technologies, Ecosystem, and Future Directions
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  15. Self-amplifying RNA COVID-19 vaccine
    Christopher J. Wayne, Anna K. Blakney · 2024 · Cell
  16. Conversion of vaccines from low to high immunogenicity by antibodies with epitope complementarity
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  17. Double methylation of tRNA-U54 to 2′-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7
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  18. Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
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  27. Nanoparticle Targeting Strategies for Lipid and Polymer‐Based Gene Delivery to Immune Cells In Vivo
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  30. Emerging prospects of mRNA cancer vaccines: mechanisms, formulations, and challenges in cancer immunotherapy
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  31. Current Non-Viral-Based Strategies to Manufacture CAR-T Cells
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  32. Pros and cons of pDNA and mRNA transfection to study mRNA translation in mammalian cells
    Dmitry E. Andreev, Ilya M. Terenin, Sergey E. Dmitriev, Ivan N. Shatsky · 2015 · Gene
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  38. mRNA-Based Vaccines and Mode of Action
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  47. Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches
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  48. Nucleic Acid Immunotherapeutics for Cancer
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  53. Modified uridines are the key to a successful message
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  54. Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis
    Masaki Gomi, Yuka Nakayama, Yu Sakurai, Ryotaro Oyama, Koki Iwasaki, Mizuki Doi, Yi Liu, Mizuho Hori, Himeka Watanabe, Kohei Hashimoto et al. · 2023 · Pharmaceuticals
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  57. Organ-targeted high-throughput in vivo biologics screen identifies materials for RNA delivery
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  58. The notorious R.N.A. in the spotlight - drug or target for the treatment of disease
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  65. State of the Art and Perspectives of Gene Therapy in Heart Failure. A Scientific Statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases
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  74. Have mRNA vaccines sentenced DNA vaccines to death?
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  75. Transfection of pseudouridine-modified mRNA encoding CPD-photolyase leads to repair of DNA damage in human keratinocytes: A new approach with future therapeutic potential
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  76. The European Regulatory Environment of RNA-Based Vaccines
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  84. Developing mRNA Nanomedicines with Advanced Targeting Functions
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  85. mRNA therapeutics: Transforming medicine through innovation in design, delivery, and disease treatment
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  86. Design principles of lipid nanoparticles for RNA delivery
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  87. Emerging modes-of-action in drug discovery
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  88. On the Shoulders of Giants — From Jenner’s Cowpox to mRNA Covid Vaccines
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  90. Advances in mRNA vaccines
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  92. mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo
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  96. mRNA cancer vaccines from bench to bedside: a new era in cancer immunotherapy
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  97. Plant-Derived Natural Compounds in Genetic Vaccination and Therapy for HPV-Associated Cancers
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