Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
Pollard, Charlotte, Rejman, Joanna, De Haes, Winni, Verrier, Bernard, Van Gulck, Ellen, Naessens, Thomas, De Smedt, Stefaan, Bogaert, Pieter +3 more·2013·Molecular Therapy
Cited by (248)
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- Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer ImmunotherapyGayathri R. Devi, Sritama Nath · 2016 · Methods in molecular biology
- Vaccine types and reverse vaccinologyAngus Nnamdi Oli, Adekunle Babajide Rowaiye · 2022 · Elsevier eBooks
- The Regulation of Nucleic Acid Vaccine Responses by the MicrobiomeAndrew M. F. Johnson, Kevin Hager, Mohamad‐Gabriel Alameh, Phuong Van, Nicole B. Potchen, Koshlan Mayer-Blackwell, Andrew J. Fiore-Gartland, Samuel S. Minot, Paulo J.C. Lin, Ying K. Tam et al. · 2023 · The Journal of Immunology
- Hitching a Ride: Enhancing Nucleic Acid Delivery into Target Cells Through NanoparticlesAlekhya Penumarthi, Preetam Basak, Peter M. Smooker, Ravi Shukla · 2020 · Environmental chemistry for a sustainable world
- Engineered protein circuits for cancer therapyAndrew C. Lu, Lukas Moeller, Stephen Moore, Kevin Ho, Victoria Tobin, Albert Qiang, Evan Zhang, Zhijie Li, Mengmeng Wang, Shiyu Xia et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Technological advances in mRNA delivery and engineering for therapeutic cancer vaccinesSatoshi Uchida · 2025 · Japanese Journal of Clinical Oncology
- Feasibility of Using a Type I IFN-Based Non-Animal Approach to Predict Vaccine Efficacy and Safety ProfilesHanin Abdel–Haq · 2024 · Vaccines
- Effectiveness of and Immune Responses to SARS-CoV-2 mRNA Vaccines and Their MechanismsEiichi Gohda · 2022 · Journal of Disaster Research
- Applications of advances in mRNA-based platforms as therapeutics and diagnostics in reproductive technologiesWjdan S. Bafleh, Haia M. R. Abdulsamad, Sally M. Al-Qaraghuli, Riwa Y. El Khatib, Rawdah Taha Elbahrawi, Azhar Mohamud Abdukadir, Shaima M. Alsawae, Zakia Dimassi, Hamdan Hamdan, Junaid Kashir · 2023 · Frontiers in Cell and Developmental Biology
- Development of Self‐Adjuvants in mRNA Vaccine and Its Application in Disease Prevention and TreatmentHuaibin Yu, Yafang Lu, Zhuorong Miao, Zhengbao Zha, Shaoqin Liu · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
- mRNA Technology a Promising Strategy for Rapid Response Vaccine Applications against the Emerging Infectious DiseasesAnju Kaushal · 2021 · ACTA SCIENTIFIC MICROBIOLOGY
- Chikungunya Virus Vaccine: An Update ReviewMohd Sayeed Shaikh, Md. Faiyazuddin, Mubasshera Sabir Khan, Shahbaz K. Pathan, Imran J. Syed, Mohammad Shabib Akhtar, Ranjit Sah, Rachana Mehta, Sanjit Kumar Sah, D. Katterine Bonilla‐Aldana et al. · 2024 · Preprints.org
- Protective Efficacy of Two Novel DNA Vaccine Candidates Encoding TgGRA28 and TgGRA83 with an IL-28B Molecular Adjuvant Against Acute and Chronic Toxoplasmosis in MiceJun Fang, Jingqi Mu, Rui Li, Jia Chen · 2025 · Vaccines
- Development of a DC-targeting Salmonella- amplifying RNA vector platform co-delivering dual antigens and adjuvants for enhanced protection against H9N2 avian influenzaMingyue Wang, Yupeng Gao, Yuxi Zhang, Tianrui Yang, Yuhang Zhang, Yan Sun, Qiyu Guo, Gerui Zhang, Jinshuo Gong, Zhannan Wang et al. · 2026 · Veterinary Microbiology
- mRNA Based Vaccine Studies in Infectious Diseases and Current DevelopmentsÜmit Savaşçı, Hanefi Cem Gül · 2021 · Journal of Molecular Virology and Immunology
- Adjuvants, the Elephant in the Room for RNA VaccinesSigrid D’haese, Sabine den Roover, Joeri L. Aerts · 2022 · RNA technologies
- Nanotechnology in vaccines and personalized medicineMarli S.P. Azevedo, Anil K. Patri · 2023 · Elsevier eBooks
- Role of Peptide Molecular Conformation in Improving the Gene Delivery Efficiency of Liposomal FormulationsYaohui Du, Chuanmei Tang, Bowen Li, Lei Yue, Rongxin Su, Wei Dong Qi, Xianbao Cui, Yuefei Wang · 2025 · Langmuir
- ARN mensajero (mRNA), una molécula con potencial aplicación terapéutica y preventivaGabriela Rosas, Raúl José Bobes, Jacquelynne Brenda Cervantes‐Torres, Edda Sciutto, Gladis Fragoso · 2022 · Inventio, la génesis de la cultura universitaria en Morelos
- The use of modified mRNA encoding platelet-derived growth factor-BB as an innovation in periodontal regenerationTheeraphat Surisaeng, Chantrakorn Champaiboon, Sathit Pichyangkul · 2019
- Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminantJingjing Zhang, Chao Li, Yuheng Liu, Rui Liao, Dian He, Lifeng Xu, Tingting Chen, Qin Xiao, Mingxing Luo, Yang Chen et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- mRNA Vaccines for HIV‐1Paolo Lusso · 2024 · Wiley eBooks
- RNA Nanoparticles as Potential VaccinesRobert K. DeLong · 2016
- Utilization of modified mRNA encoding bone morphogenetic protein-2 for periodontal regeneration: an in vitro studyPromphakkon Kulthanaamondhita, Rangsini Mahanonda, Sathit Pichyangkul · 2019
- The RNA World: The Best of Times, the Worst of TimesThierry VandenDriessche · 2021 · Human Gene Therapy
- mRNA AŞILARINDA GÜNCEL YAKLAŞIMLARKamil BATUR, Hakan Yardımcı · 2022 · Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni
- Faculty Opinions recommendation of Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose.Donald A. Tomalia · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Vacinas baseadas em RNA mensageiro formuladas em nanopartículas lipídicas para tratamento de tumores induzidos pelo HPV-16.Jamile Ramos da Silva · 2021
- Messenger RNA Nanovaccine in Cancer ImmunotherapyMengyun Li, Hongxia Zhang · 2022 · Springer eBooks
- Protein expression after gingival injection of messenger RNA encoding platelet-derived growth factor-bb in ligature-induced rat periodontitisPimphorn Meekhantong, Rangsini Mahanonda, Wichaya Wisitrasameewong · 2022
- Expression of vascular endothelial growth factor protein in mRNA-transfected human periodontal ligament cellsMana Naratippakorn · 2021
- Generation of liver tissue-resident memory T cells with novel NKT cell agonists and mRNA vaccinesMitch Ganley · 2024
- mRNA vaccines for COVID-19Anya M Hillery · 2024 · Elsevier eBooks
- The Value of a Comparative Approach with Equine Vaccine Development for the Development of Human Influenza DNA VaccinesAhmed F. Abdelkhalek, Janet M. Daly · 2024 · Zoonotic Diseases
- mRNA vaccines: the next frontier in disease preventionQuratul ain Babar, Maryam Maryam, ALI MUSTAPHA MUHAMMAD, Muhammad Farrukh Tahir, Anwar Mohamed Ali · 2024 · Elsevier eBooks
- Cancer Vaccines Based on mRNA: Hype or Hope?Wout de Mey, Dorien Autaers, Giada Bertazzon, Arthur Esprit, Marta Marco Aragon, Lorenzo Franceschini, Karine Breckpot · 2024 · Wiley eBooks
- mRNA vaccines for gastrointestinal cancers: a paradigm shift in treatmentHashem Ahmad Abu Harirah, Suleiman Ibrahim Shelash Mohammad, Asokan Vasudevan, Vicky D. Jain, Subasini Uthirapathy, Subbulakshmi Ganesan, Deepak Bhanot, K. Satyam Naidu, Yasser Fakri Mustafa, Zahraa Haleem Al‐qaim · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Combinational adjuvants delivered by ink-jet potentiate naked mRNA vaccines for robust protection against infectious diseasesNan Qiao, Junichi Ishikawa, Fumihiko Yasui, Kaori Sano, Kei Miyakawa, Akimasa Hayashi, Ahmad Faisal Amiry, Liu Haonan, Zhu Xueyang, Taku Sato et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- LNP-mRNA immunogenicity and toxicityMaharshi Thalla, Shashank Reddy Pasika, Raviteja Bulusu, D S Reddy, Varsha Mundrathi, Prashant Shukla · 2026 · Elsevier eBooks
- Formulation et vectorisation d’un ARN messager vaccinal codant l’antigène Gag du VIH-1 à l’aide de nanoparticules biodégradables de poly(acide lactique)Anne-Line Coolen · 2018
- Rôles des interférons dans la physiopathologie des myopathies inflammatoiresCyrielle Hou · 2021 · theses.fr (ABES)
- Optimising a mRNA Vaccine platform against HIV-1 : from the in vitro transcription design to envelope protein expressionSergio Linares-Fernández · 2021
- Optimization of a liver Trm cell-inducing mRNA vaccine by reduction of type I interferon responseJordan James Minnell, Mitch Ganley, Ariane R. Lee, Taylah Phabmixay, Kathryn J. Farrand, Olivia K. Burn, John C. Mamum, Emma Lamb, Sarah L. Draper, Susanna T. S. Chan et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- SARS‐CoV‐2 mRNA Vaccination Induces Neutralizing Antibodies and Type I IFN Changes in People Living With HIVFederica Frasca, Luca Maddaloni, Alessandra D’Auria, Matteo Fracella, Ginevra Bugani, C Falvino, Valentina Baccolini, Giuseppe Migliara, Francesca Aloisi, Letizia Santinelli et al. · 2026 · Journal of Medical Virology
- Neoantigen cancer vaccines for gastrointestinal tumors: opportunities and challengesZixuan Zhao, Xinyu Du, Xiaoliang Gao, Sheng Zhao, Liang Zhang, Yongzhan Nie · 2026 · MedScience
- In Vitro Cell Proliferation, Osteogenic Differentiation, and In Vivo Angiogenesis Induced by Modified mRNA Encoding Vascular Endothelial Growth Factor‐ANoppadol Sa‐Ard‐Iam, Mana Naratippakorn, Chantrakorn Champaiboon · 2026 · International Journal of Dentistry