Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines

Pollard, Charlotte, Rejman, Joanna, De Haes, Winni, Verrier, Bernard, Van Gulck, Ellen, Naessens, Thomas, De Smedt, Stefaan, Bogaert, Pieter +3 more·2013·Molecular Therapy

Cited by (248)

Items 201–248 of 248

  1. Advances in mRNA vaccines for viral diseases
    Yukai Huang, Xuerui Zhu, Xiao Guo, Yuancheng Zhou, Dongying Liu, Jingrui Mao, Yongai Xiong, Youcai Deng, Xinghong Gao · 2023 · Journal of Medical Virology
  2. Targeted suppression of type 1 interferon signaling during RNA delivery enhances vaccine-elicited immunity
    Byungji Kim, Ryan Ramsey Hosn, Tanaka K. Remba, Jonathan Dye, Howard H. Mak, Jae Yun Jeong, Milton R. Cornwall-Brady, Wuhbet D. Abraham, Laura Maiorino, Mariane B. Melo et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy
    Gayathri R. Devi, Sritama Nath · 2016 · Methods in molecular biology
  4. Vaccine types and reverse vaccinology
    Angus Nnamdi Oli, Adekunle Babajide Rowaiye · 2022 · Elsevier eBooks
  5. The Regulation of Nucleic Acid Vaccine Responses by the Microbiome
    Andrew M. F. Johnson, Kevin Hager, Mohamad‐Gabriel Alameh, Phuong Van, Nicole B. Potchen, Koshlan Mayer-Blackwell, Andrew J. Fiore-Gartland, Samuel S. Minot, Paulo J.C. Lin, Ying K. Tam et al. · 2023 · The Journal of Immunology
  6. Hitching a Ride: Enhancing Nucleic Acid Delivery into Target Cells Through Nanoparticles
    Alekhya Penumarthi, Preetam Basak, Peter M. Smooker, Ravi Shukla · 2020 · Environmental chemistry for a sustainable world
  7. Engineered protein circuits for cancer therapy
    Andrew C. Lu, Lukas Moeller, Stephen Moore, Kevin Ho, Victoria Tobin, Albert Qiang, Evan Zhang, Zhijie Li, Mengmeng Wang, Shiyu Xia et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Technological advances in mRNA delivery and engineering for therapeutic cancer vaccines
    Satoshi Uchida · 2025 · Japanese Journal of Clinical Oncology
  9. Feasibility of Using a Type I IFN-Based Non-Animal Approach to Predict Vaccine Efficacy and Safety Profiles
    Hanin Abdel–Haq · 2024 · Vaccines
  10. Effectiveness of and Immune Responses to SARS-CoV-2 mRNA Vaccines and Their Mechanisms
    Eiichi Gohda · 2022 · Journal of Disaster Research
  11. Applications of advances in mRNA-based platforms as therapeutics and diagnostics in reproductive technologies
    Wjdan S. Bafleh, Haia M. R. Abdulsamad, Sally M. Al-Qaraghuli, Riwa Y. El Khatib, Rawdah Taha Elbahrawi, Azhar Mohamud Abdukadir, Shaima M. Alsawae, Zakia Dimassi, Hamdan Hamdan, Junaid Kashir · 2023 · Frontiers in Cell and Developmental Biology
  12. Development of Self‐Adjuvants in mRNA Vaccine and Its Application in Disease Prevention and Treatment
    Huaibin Yu, Yafang Lu, Zhuorong Miao, Zhengbao Zha, Shaoqin Liu · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  13. mRNA Technology a Promising Strategy for Rapid Response Vaccine Applications against the Emerging Infectious Diseases
    Anju Kaushal · 2021 · ACTA SCIENTIFIC MICROBIOLOGY
  14. Chikungunya Virus Vaccine: An Update Review
    Mohd Sayeed Shaikh, Md. Faiyazuddin, Mubasshera Sabir Khan, Shahbaz K. Pathan, Imran J. Syed, Mohammad Shabib Akhtar, Ranjit Sah, Rachana Mehta, Sanjit Kumar Sah, D. Katterine Bonilla‐Aldana et al. · 2024 · Preprints.org
  15. Protective Efficacy of Two Novel DNA Vaccine Candidates Encoding TgGRA28 and TgGRA83 with an IL-28B Molecular Adjuvant Against Acute and Chronic Toxoplasmosis in Mice
    Jun Fang, Jingqi Mu, Rui Li, Jia Chen · 2025 · Vaccines
  16. Development of a DC-targeting Salmonella- amplifying RNA vector platform co-delivering dual antigens and adjuvants for enhanced protection against H9N2 avian influenza
    Mingyue Wang, Yupeng Gao, Yuxi Zhang, Tianrui Yang, Yuhang Zhang, Yan Sun, Qiyu Guo, Gerui Zhang, Jinshuo Gong, Zhannan Wang et al. · 2026 · Veterinary Microbiology
  17. mRNA Based Vaccine Studies in Infectious Diseases and Current Developments
    Ümit Savaşçı, Hanefi Cem Gül · 2021 · Journal of Molecular Virology and Immunology
  18. Adjuvants, the Elephant in the Room for RNA Vaccines
    Sigrid D’haese, Sabine den Roover, Joeri L. Aerts · 2022 · RNA technologies
  19. Nanotechnology in vaccines and personalized medicine
    Marli S.P. Azevedo, Anil K. Patri · 2023 · Elsevier eBooks
  20. Role of Peptide Molecular Conformation in Improving the Gene Delivery Efficiency of Liposomal Formulations
    Yaohui Du, Chuanmei Tang, Bowen Li, Lei Yue, Rongxin Su, Wei Dong Qi, Xianbao Cui, Yuefei Wang · 2025 · Langmuir
  21. ARN mensajero (mRNA), una molécula con potencial aplicación terapéutica y preventiva
    Gabriela Rosas, Raúl José Bobes, Jacquelynne Brenda Cervantes‐Torres, Edda Sciutto, Gladis Fragoso · 2022 · Inventio, la génesis de la cultura universitaria en Morelos
  22. The use of modified mRNA encoding platelet-derived growth factor-BB as an innovation in periodontal regeneration
    Theeraphat Surisaeng, Chantrakorn Champaiboon, Sathit Pichyangkul · 2019
  23. Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant
    Jingjing Zhang, Chao Li, Yuheng Liu, Rui Liao, Dian He, Lifeng Xu, Tingting Chen, Qin Xiao, Mingxing Luo, Yang Chen et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  24. mRNA Vaccines for HIV‐1
    Paolo Lusso · 2024 · Wiley eBooks
  25. RNA Nanoparticles as Potential Vaccines
    Robert K. DeLong · 2016
  26. Utilization of modified mRNA encoding bone morphogenetic protein-2 for periodontal regeneration: an in vitro study
    Promphakkon Kulthanaamondhita, Rangsini Mahanonda, Sathit Pichyangkul · 2019
  27. The RNA World: The Best of Times, the Worst of Times
    Thierry VandenDriessche · 2021 · Human Gene Therapy
  28. mRNA AŞILARINDA GÜNCEL YAKLAŞIMLAR
    Kamil BATUR, Hakan Yardımcı · 2022 · Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni
  29. Faculty Opinions recommendation of Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose.
    Donald A. Tomalia · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  30. Vacinas baseadas em RNA mensageiro formuladas em nanopartículas lipídicas para tratamento de tumores induzidos pelo HPV-16.
    Jamile Ramos da Silva · 2021
  31. Messenger RNA Nanovaccine in Cancer Immunotherapy
    Mengyun Li, Hongxia Zhang · 2022 · Springer eBooks
  32. Protein expression after gingival injection of messenger RNA encoding platelet-derived growth factor-bb in ligature-induced rat periodontitis
    Pimphorn Meekhantong, Rangsini Mahanonda, Wichaya Wisitrasameewong · 2022
  33. Expression of vascular endothelial growth factor protein in mRNA-transfected human periodontal ligament cells
    Mana Naratippakorn · 2021
  34. Generation of liver tissue-resident memory T cells with novel NKT cell agonists and mRNA vaccines
    Mitch Ganley · 2024
  35. mRNA vaccines for COVID-19
    Anya M Hillery · 2024 · Elsevier eBooks
  36. The Value of a Comparative Approach with Equine Vaccine Development for the Development of Human Influenza DNA Vaccines
    Ahmed F. Abdelkhalek, Janet M. Daly · 2024 · Zoonotic Diseases
  37. mRNA vaccines: the next frontier in disease prevention
    Quratul ain Babar, Maryam Maryam, ALI MUSTAPHA MUHAMMAD, Muhammad Farrukh Tahir, Anwar Mohamed Ali · 2024 · Elsevier eBooks
  38. Cancer Vaccines Based on mRNA: Hype or Hope?
    Wout de Mey, Dorien Autaers, Giada Bertazzon, Arthur Esprit, Marta Marco Aragon, Lorenzo Franceschini, Karine Breckpot · 2024 · Wiley eBooks
  39. mRNA vaccines for gastrointestinal cancers: a paradigm shift in treatment
    Hashem Ahmad Abu Harirah, Suleiman Ibrahim Shelash Mohammad, Asokan Vasudevan, Vicky D. Jain, Subasini Uthirapathy, Subbulakshmi Ganesan, Deepak Bhanot, K. Satyam Naidu, Yasser Fakri Mustafa, Zahraa Haleem Al‐qaim · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  40. Combinational adjuvants delivered by ink-jet potentiate naked mRNA vaccines for robust protection against infectious diseases
    Nan Qiao, Junichi Ishikawa, Fumihiko Yasui, Kaori Sano, Kei Miyakawa, Akimasa Hayashi, Ahmad Faisal Amiry, Liu Haonan, Zhu Xueyang, Taku Sato et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  41. LNP-mRNA immunogenicity and toxicity
    Maharshi Thalla, Shashank Reddy Pasika, Raviteja Bulusu, D S Reddy, Varsha Mundrathi, Prashant Shukla · 2026 · Elsevier eBooks
  42. Formulation et vectorisation d’un ARN messager vaccinal codant l’antigène Gag du VIH-1 à l’aide de nanoparticules biodégradables de poly(acide lactique)
    Anne-Line Coolen · 2018
  43. Rôles des interférons dans la physiopathologie des myopathies inflammatoires
    Cyrielle Hou · 2021 · theses.fr (ABES)
  44. Optimising a mRNA Vaccine platform against HIV-1 : from the in vitro transcription design to envelope protein expression
    Sergio Linares-Fernández · 2021
  45. Optimization of a liver Trm cell-inducing mRNA vaccine by reduction of type I interferon response
    Jordan James Minnell, Mitch Ganley, Ariane R. Lee, Taylah Phabmixay, Kathryn J. Farrand, Olivia K. Burn, John C. Mamum, Emma Lamb, Sarah L. Draper, Susanna T. S. Chan et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  46. SARS‐CoV‐2 mRNA Vaccination Induces Neutralizing Antibodies and Type I IFN Changes in People Living With HIV
    Federica Frasca, Luca Maddaloni, Alessandra D’Auria, Matteo Fracella, Ginevra Bugani, C Falvino, Valentina Baccolini, Giuseppe Migliara, Francesca Aloisi, Letizia Santinelli et al. · 2026 · Journal of Medical Virology
  47. Neoantigen cancer vaccines for gastrointestinal tumors: opportunities and challenges
    Zixuan Zhao, Xinyu Du, Xiaoliang Gao, Sheng Zhao, Liang Zhang, Yongzhan Nie · 2026 · MedScience
  48. In Vitro Cell Proliferation, Osteogenic Differentiation, and In Vivo Angiogenesis Induced by Modified mRNA Encoding Vascular Endothelial Growth Factor‐A
    Noppadol Sa‐Ard‐Iam, Mana Naratippakorn, Chantrakorn Champaiboon · 2026 · International Journal of Dentistry