Pharmaco-metabonomic phenotyping and personalized drug treatment

Andrew Clayton, T., Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc +4 more·2006·Nature

Cited by (747)

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    Debashis Sarker, Simon Pacey, Paul Workman · 2007 · Biomarkers in Medicine
  2. Metabotyping for the development of tailored dietary advice solutions in a European population: the Food4Me study
    Clare B. O’Donovan, Marianne C. Walsh, Clara Woolhead, Hannah Forster, Carlos A. Celis-Morales, Rosalind Fallaize, Anna L. Macready, Cyril F. M. Marsaux, Santiago Navas‐Carretero, Rodrigo San-Cristóbal et al. · 2017 · British Journal Of Nutrition
  3. A serum metabolomic analysis for diagnosis and biomarker discovery of primary biliary cirrhosis and autoimmune hepatitis.
    J. Lian, Wei Liu, S. Hao, D. Chen, Yinyin Wang, Jian-Le Yang, H. Jia, Jian-Rong Huang · 2015 · Hepatobiliary & Pancreatic Diseases International
  4. Pharmacogenetic Markers of Drug Efficacy and Toxicity
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  5. Systems Biology Approaches for Inflammatory Bowel Disease
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  6. Two faces of microbiota in inflammatory and autoimmune diseases: triggers and drugs
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  7. Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response.
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  8. Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity.
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  10. Statistical integration of 1H NMR and MRS data from different biofluids and tissues enhances recovery of biological information from individuals with HIV-1 infection.
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  14. Metabolomics: Integration of a New “Omics” with Clinical Pharmacology
    L. James · 2013 · Clinical pharmacology and therapy
  15. A metabonomic approach for mechanistic exploration of pre-clinical toxicology
    Muireann Coen · 2010 · Toxicology
  16. Metabolomic biomarkers: their role in the critical path
    Laura K. Schnackenberg, Richard D. Beger · 2007 · Drug Discovery Today Technologies
  17. Chapter 1 – Metabonomics and Metabolomics Techniques and Their Applications in Mammalian Systems
    J. Nicholson, E. Holmes, J. Lindon · 2007 · Elsevier eBooks
  18. Pharmaco-Multiomics: A New Frontier in Precision Psychiatry
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    M. Leonti, L. Casu, D. T. de Oliveira Martins, E. Rodrigues, G. Benítez · 2020 · Revista Brasileira de Farmacognosia
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  21. 1H NMR‐based metabonomic applications to decipher gut microbial metabolic influence on mammalian health
    François‐Pierre Martin, Sebastiano Collino, Serge Rezzi · 2011 · Magnetic Resonance in Chemistry
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    Paula Iruzubieta, M. Arias, Lucía Barbier‐Torres, Maria Luz Martínez‐Chantar, Javier Crespo · 2015 · BioMed Research International
  24. Metabolomics for rheumatic diseases: has the time come?
    L. Semerano, P. Roméo, M. Boissier · 2015 · Annals of the Rheumatic Diseases
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    Sishuo Cao, Xiaoyun He, Wentao Xu, Yunbo Luo, Yanfang Yuan, Pengfei Liu, Bo Cao, Hui Shi, Kunlun Huang · 2012 · IUBMB Life
  26. Investigation of endogenous metabolic changes in the urine of pseudo germ-free rats using a metabolomic approach
    Soo Hyun Lee, Ji Hye An, Hyun‐Mee Park, Byung Hwa Jung · 2012 · Journal of Chromatography B
  27. Metabolomics and biomarker discovery: NMR spectral data of urine and hepatotoxicity by carbon tetrachloride, acetaminophen, and d-galactosamine in rats
    Kyu-Bong Kim, M. Chung, S. Um, J. Oh, Seon Hwa Kim, Mitin Na, Hye-Young Oh, W. Cho, K. Choi · 2008 · Metabolomics
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    Oriol Juanola, Mohsin Hassan, Pavitra Kumar, Bahtiyar Yılmaz, Irene Keller, Cédric Simillion, Cornelius Engelmann, Frank Tacke, Jean‐François Dufour, Andrea De Gottardi et al. · 2021 · Gut Microbes
  29. Metabolomics in pharmacology - a delve into the novel field of pharmacometabolomics
    Michele Mussap, Cristina Loddo, Claudia Fanni, Vassilios Fanos · 2020 · Expert Review of Clinical Pharmacology
  30. Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid
    N. Zheng, Yu Gu, Ying Hong, Lili Sheng, Lin-Lin Chen, Feng Zhang, J. Hou, Wei-Dong Zhang, Ze-An Zhang, Wei Jia et al. · 2019 · Journal of Pharmaceutical Analysis
  31. Neurochemical Metabolomics Reveals Disruption to Sphingolipid Metabolism Following Chronic Haloperidol Administration
    Joseph L. McClay, Sarah A. Vunck, Angela M. Batman, James J. Crowley, Robert E. Vann, Patrick M. Beardsley, Edwin J. C. G. van den Oord · 2015 · Journal of Neuroimmune Pharmacology
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    Nataša Karas-Kuželički, A. Šmid, Riin Tamm, A. Metspalu, I. Mlinarič-Raščan · 2014 · Pharmacogenomics (London)
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    Hyuk‐Hwan Song, Ji Young Moon, Hyung Won Ryu, Bong‐Soo Noh, Jeong‐Han Kim, Hyeong‐Kyu Lee, Sei‐Ryang Oh · 2014 · Journal of Ginseng Research
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    Guoxiang Xie, Xin Li, Houkai Li, Wei Ping Jia · 2013 · Journal of Proteome Research
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    Cecilia Castro, C. Manetti · 2007 · Analytical Biochemistry
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    Die Dai, Yuan Tian, Huimin Guo, Pei Zhang, Yin Huang, Wei Zhang, Fengguo Xu, Zunjian Zhang · 2015 · Metabolomics
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    Jingai Jian, Donglin He, Song-Yan Gao, Xia Tao, Xin Dong · 2023 · Pharmaceuticals
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    Jeremy Ramsey Everett, Elaine C. Holmes, Kirill Veselkov, John C. Lindon, Jeremy Kirk Nicholson · 2019 · Trends in Pharmacological Sciences
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    A. Vignoli, B. Orlandini, L. Tenori, M. Biagini, S. Milani, D. Renzi, C. Luchinat, A. Calabrò · 2018 · Journal of Proteome Research
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    Θεοδώρα Κάτσιλα, Evangelia K. Konstantinou, Ioanna Lavda, Harilaos Malakis, Ioanna Papantoni, Lamprini Skondra, George P. Patrinos · 2016 · EBioMedicine
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    Zhao-Xia Miao, Meng-Xia Jin, Xia Liu, Wei Guo, Xiang-Ju Jin, Hongyue Liu, Ying-Hong Wang · 2015 · Analytical and Bioanalytical Chemistry
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    Kuo-Ching Wang, San Y. Wang, Ching-Hua Kuo, Y. Tseng · 2013 · Analytical Chemistry
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    Jiye Aa, Guangji Wang, Haiping Hao, Qing Bo Huang, Yihong Lu, Bei Yan, Weibin Zha, Linsheng Liu, Kang An · 2010 · Acta Pharmacologica Sinica
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    Merriline M. Satyamitra, David R. Cassatt, Brynn A. Hollingsworth, Paul W. Price, Carmen I. Rios, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo · 2020 · Metabolites
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    E. Gomes, S. Kuyucu · 2017 · Current Treatment Options in Allergy
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    Peiyuan Yin, Guo-Wang Xu · 2013 · Expert Review of Molecular Diagnostics
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    Hye-ji Yang, Myung-Joo Choi, H. Wen, H. Kwon, K. Jung, Sang-Won Hong, Joon-Mee Kim, Soon-Sun Hong, Sunghyouk Park · 2011 · PLoS ONE
  48. Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol.
    W. Schoonen, C. Kloks, J. Ploemen, G. Horbach, M. Smit, P. Zandberg, J. Mellema, C. V. Zuylen, A. Tas, J. V. van Nesselrooij et al. · 2007 · Toxicological Sciences
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    Wang, Xi, Yan, Shi‐Kai, Dai, Wei‐Xing, Liu, Xin‐Ru, Zhang, Wei‐Dong, Wang, Jie‐Jun · 2010 · International Journal of Cancer
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    Qingyu Hu, Huiru Tang, Yulan Wang · 2020 · Journal of Analysis and Testing
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    Mika Ala‐Korpela, George Davey Smith · 2016 · International Journal of Epidemiology
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    Ilaria Lauri, F. Savorani, N. Iaccarino, P. Zizza, L. Pavone, E. Novellino, S. Engelsen, A. Randazzo · 2016 · Metabolites
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    Peng-Cheng Zhang, A. Cheetham, L. Lock, Ya-Ping Li, H. Cui · 2015 · Current Opinion in Biotechnology
  54. A smartphone metabolomics platform and its application to the assessment of cisplatin-induced kidney toxicity
    Hyuk Nam Kwon, Jooeun Park, Yong An, Jaeho Sim, Sunghyouk Park · 2014 · Analytica Chimica Acta
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    Laneke Villiers, Du Toit Loots · 2014 · Current Metabolomics
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    Alejandro R. Burga, Ben Lehner · 2013 · Current Opinion in Biotechnology
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    Richard D. Beger, Thomas J. Colatsky · 2011 · Metabolomics
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  61. The Role of Metabolic Biomarkers in Drug Toxicity Studies
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    Elin Pohjanen, Elin Thysell, J. Lindberg, I. Schuppe-Koistinen, T. Moritz, Pär Jonsson, Henrik Antti · 2007 · Metabolomics
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    Sarah K. Davies, J. G. Bundy, A. Leroi · 2015 · Journal of Proteome Research
  97. Using systems approaches to address challenges for clinical implementation of pharmacogenomics
    Jason H. Karnes, Sara L. Van Driest, Erica Bowton, Peter Weeke, Jonathan D. Mosley, Josh F. Peterson, Joshua C. Denny, Dan M. Roden · 2013 · WIREs Systems Biology and Medicine
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  100. Personalized medicine progresses
    J. Haselden, A. Nicholls · 2006 · Nature Medicine