The prion protein as a receptor for amyloid-β
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Items 101–200 of 253
- Prion Protein: The Molecule of Many Forms and FacesValerija Kovač, Vladka Čurin Šerbec · 2022 · International Journal of Molecular Sciences
- Cellular Prion Protein as a Therapeutic Target in Alzheimer's DiseaseJuha Laurén · 2013 · Journal of Alzheimer s Disease
- The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cellsElena De Cecco, Luigi Celauro, Silvia Vanni, Micaela Grandolfo, Edoardo Bistaffa, Fabio Moda, Adriano Aguzzi, Giuseppe Legname · 2020 · Journal of Neurochemistry
- Mechanisms of prion-induced neurodegenerationPaula Saá, David A. Harris, Larisa Červen̆áková · 2016 · Expert Reviews in Molecular Medicine
- Inhibition of group-I metabotropic glutamate receptors protects against prion toxicityDespoina Goniotaki, Asvin KK Lakkaraju, Amulya Nidhi Shrivastava, Pamela Bakirci, Silvia Sorce, Assunta Senatore, Rajlakshmi Marpakwar, Simone Hornemann, Fabrizio Gasparini, Antoine Triller et al. · 2017 · PLoS Pathogens
- Cellular Prion Protein Regulates Its Own α-Cleavage through ADAM8 in Skeletal MuscleJingjing Liang, Wei Wang, Debra Sorensen, Sarah J. Medina, Sergei A. Ilchenko, Janna Kiselar, Witold K. Surewicz, Stephanie A. Booth, Qingzhong Kong · 2012 · Journal of Biological Chemistry
- Allosteric function and dysfunction of the prion proteinRafael Linden, Yraima Cordeiro, Luís Maurício T. R. Lima · 2011 · Cellular and Molecular Life Sciences
- Single‐Molecule Imaging Reveals that Small Amyloid‐β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC)Kristina A. Ganzinger, Priyanka S. Narayan, Seema Qamar, Laura Weimann, Rohan T. Ranasinghe, Adriano Aguzzi, Christopher Martin Dobson, James T. McColl, Peter St George‐Hyslop, David Klenerman · 2014 · ChemBioChem
- Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's diseaseJonah J. Scott-McKean, Krystyna A. Surewicz, Jin-Kyu Choi, Vernon A. Ruffin, Ahlam Salameh, Krzysztof Nieznański, Alberto C. S. Costa, Witold K. Surewicz · 2016 · Neurobiology of Disease
- HLA in Alzheimer’s Disease: Genetic Association and Possible Pathogenic RolesZixuan Wang, Qi Wan, Ang Xing · 2020 · NeuroMolecular Medicine
- Early Molecular Changes in Alzheimer Disease: Can We Catch the Disease in its Presymptomatic Phase?Kerstin T.S. Wirz, Stella Keitel, Dick Frans Swaab, Joost Verhaagen, Koen Bossers · 2013 · Journal of Alzheimer s Disease
- Protein Co-Aggregation Related to Amyloids: Methods of Investigation, Diversity, and ClassificationStanislav A. Bondarev, Kirill S. Antonets, Andrey V. Kajava, Anton A. Nizhnikov, Galina A. Zhouravleva · 2018 · International Journal of Molecular Sciences
- The cellular prion protein (PrPC) as neuronal receptor for α-synucleinLaura Urrea, Isidró Ferrer, Rosalina Gavı́n, José Antonio del Rı́o · 2017 · Prion
- Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer's diseaseElena Anahí Bignante, Florencia Heredia, Gerardo A. Morfini, Alfredo Lorenzo · 2013 · Neurobiology of Aging
- Aβ induces its own prion protein N-terminal fragment (PrPN1)–mediated neutralization in amorphous aggregatesMaxime Béland, Mikaël Bédard, Guillaume Tremblay, Pierre Lavigne, Xavier Roucou · 2014 · Neurobiology of Aging
- Regulation of spine structural plasticity by Arc/Arg3.1Thomas M. Newpher, Scott C. Harris, Jasmine Pringle, Colleen Hamilton, Scott H. Soderling · 2017 · Seminars in Cell and Developmental Biology
- Cellular prion protein targets amyloid-β fibril ends via its C-terminal domain to prevent elongationErin Bove‐Fenderson, Ryo Urano, John E. Straub, David A. Harris · 2017 · Journal of Biological Chemistry
- The Role of Exosomes in Stemness and Neurodegenerative Diseases—Chemoresistant-Cancer Therapeutics and PhytochemicalsNarasimha Murthy Beeraka, Shalini H. Doreswamy, Surya Prabha Sadhu, Asha Srinivasan, Rajeswara Rao Pragada, SubbaRao V. Madhunapantula, Gjumrakch Aliev · 2020 · International Journal of Molecular Sciences
- Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based AssayEmmanuel Risse, Andrew J. Nicoll, William A. Taylor, Daniel Wright, Mayank Badoni, Xiaofan Yang, Mark A. Farrow, John Collinge · 2015 · Journal of Biological Chemistry
- Prion protein and agingLisa Gasperini, Giuseppe Legname · 2014 · Frontiers in Cell and Developmental Biology
- Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopyAnna S. König, Nadine S. Rösener, Lothar Gremer, Markus Tusche, Daniel Flender, Elke Reinartz, Wolfgang Hoyer, Philipp Neudecker, Dieter Willbold, Henrike Heise · 2021 · Journal of Biological Chemistry
- Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloidsRon Balczon, Kyle Adam Morrow, Chun Zhou, B. Douglas Edmonds, Mikhail F. ALEXEYEV, Jean‐François Pittet, Brant M. Wagener, Stephen A. Moser, Silas J. Leavesley, Xiang‐ming Zha et al. · 2017 · The FASEB Journal
- The role of the prion protein in the internalization of α-synuclein amyloidsElena De Cecco, Giuseppe Legname · 2018 · Prion
- Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's diseaseNadine D. Younan, Ko‐Fan Chen, Ruth‐Sarah Rose, Damian C. Crowther, John H. Viles · 2018 · Journal of Biological Chemistry
- A ‘danse macabre’: tau and F yn in STEP with amyloid beta to facilitate induction of synaptic depression and excitotoxicityJannic Boehm · 2013 · European Journal of Neuroscience
- Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's diseaseValeriy G. Ostapchenko, Flávio H. Beraldo, André Luiz Sena Guimarães, Sanju Mishra, Mónica S. Guzmán, Jue Fan, Vilma Regina Martins, Vânia F. Prado, Marco A. M. Prado · 2013 · Journal of Neurochemistry
- Modeling Alzheimer’s disease with human iPS cells: advancements, lessons, and applicationsSofia Essayan-Perez, Bo Zhou, Amber M. Nabet, Marius Wernig, Yu‐Wen Alvin Huang · 2019 · Neurobiology of Disease
- Characterizing affinity epitopes between prion protein and β-amyloid using an epitope mapping immunoassayMino Kang, Su Yeon Kim, Seong Soo A. An, Young Ran Ju · 2013 · Experimental & Molecular Medicine
- Beta-Amyloid Peptides Enhance the Proliferative Response of Activated CD4+CD28+ Lymphocytes from Alzheimer Disease Patients and from Healthy ElderlyAgnieszka Jóźwik, Jerzy Landowski, Leszek Bidzan, Tamàs Fülöp, Ewa Bryl, Jacek Maciej Witkowski · 2012 · PLoS ONE
- Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer’s-Associated Aβ OligomersKyle C. Wilcox, Matthew R. Marunde, Aditi Das, Pauline T. Velasco, Benjamin D. Kuhns, Michael Thomas Marty, Jiang Haoming, Chi-Hao Luan, Stephen G. Sligar, William L. Klein · 2015 · PLoS ONE
- Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptorAadilah Omar, Katarina Jovanovic, Bianca Da Costa Dias, Danielle Gonsalves, Kiashanee Moodley, R. J. Caveney, Vusi Gordon Mbazima, Stefan F. T. Weiss · 2010 · Expert Opinion on Therapeutic Patents
- Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal ActivityMiyamoto, Takashi, Kim, Daniel, Knox, Joseph A., Johnson, Erik, Mucke, Lennart · 2016 · Journal of Biological Chemistry
- Neuroprotective and Neurotoxic Signaling by the Prion ProteinUlrike K. Resenberger, Konstanze F. Winklhofer, Jörg Tatzelt · 2011 · Topics in current chemistry
- Five Questions on Prion DiseasesAdriano Aguzzi, Caihong Zhu · 2012 · PLoS Pathogens
- Neurogranin restores amyloid β-mediated synaptic transmission and long-term potentiation deficitsKanwardeep S. Kaleka, Nashaat Zakaria Gerges · 2015 · Experimental Neurology
- Prion Protein Interactome: Identifying Novel Targets in Slowly and Rapidly Progressive Forms of Alzheimer’s DiseaseSaima Zafar, Mohsin Shafiq, Neelam Younas, Matthias Schmitz, Isidró Ferrer, Inga Zerr · 2017 · Journal of Alzheimer s Disease
- Neuroimmunoendocrine Regulation of the Prion Protein in NeutrophilsRafael Meyer Mariante, Alberto Nóbrega, Rodrigo A. P. Martins, Rômulo B. Areal, Maria Bellio, Rafael Linden · 2012 · Journal of Biological Chemistry
- Aβ Inhibition of Ionic Conductance in Mouse Basal Forebrain Neurons Is Dependent upon the Cellular Prion Protein PrPCKwai A. Alier, Li Ma, Jing Yang, David A. Westaway, Jack H. Jhamandas · 2011 · Journal of Neuroscience
- Alzheimer's Disease and Prion ProteinJiayi Zhou · 2013 · Intractable & Rare Diseases Research
- Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via the Fyn PathwayRong-Jie Chen, Wei-Wei Chang, Yu‐Chun Lin, Pei‐Lin Cheng, Yun‐Ru Chen · 2013 · ACS Chemical Neuroscience
- Molecular Pathogenesis and Interventional Strategies for Alzheimer’s Disease: Promises and PitfallsShashikala Bhute, Deepaneeta Sarmah, Aishika Datta, Pallavi Rane, Amit Shard, Avirag Goswami, Anupom Borah, Kiran Kalia, Kunjan R. Dave, Pallab Bhattacharya · 2020 · ACS Pharmacology & Translational Science
- Breaking the Code of Amyloid- β OligomersSylvain Lesné · 2013 · International Journal of Cell Biology
- Prion protein and its role in signal transductionAlessandro Didonna · 2013 · Cellular & Molecular Biology Letters
- Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1Pravas Kumar Baral, Barbara Wieland, Mridula Swayampakula, Magdalini Polymenidou, Muhammad Hafiz Rahman, Nat N. V. Kav, Adriano Aguzzi, Michael N.G. James · 2012 · Acta Crystallographica Section D Biological Crystallography
- Prion protein oligomer and its neurotoxicityPei Huang, Fulin Lian, Yi Wen, Chenyun Guo, Donghai Lin · 2013 · Acta Biochimica et Biophysica Sinica
- LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer’s DiseaseEmma C. Pinnock, Katarina Jovanovic, Maxine G. Pinto, Eloise Ferreira, Bianca Da Costa Dias, Clement Brian Penny, Stefan H.J. Knackmuss, Uwe Reusch, Melvyn Little, Hermann M. Schätzl et al. · 2015 · Journal of Alzheimer s Disease
- Role of cellular prion protein in interneuronal amyloid transmissionJosé Antonio del Rı́o, Isidró Ferrer, Rosalina Gavı́n · 2018 · Progress in Neurobiology
- Insoluble cellular prion protein and its association with prion and Alzheimer diseasesWen‐Quan Zou, Xiaochen Zhou, Jue Yuan, Xiangzhu Xiao · 2011 · Prion
- Cellular Prion Protein Mediates Toxic Signaling of Amyloid BetaUlrike K. Resenberger, Konstanze F. Winklhofer, Jörg Tatzelt · 2011 · Neurodegenerative Diseases
- On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseasesGiuseppe Legname, Carlo Scialò · 2020 · Prion
- Aß Pathology and Neuron–Glia Interactions: A Synaptocentric ViewChristiaan F. M. Huffels, Jinte Middeldorp, Elly M. Hol · 2022 · Neurochemical Research
- Advances in fluorescent probes for detection and imaging of amyloid-β peptides in Alzheimer's diseaseYunhua Zhang, Cen Ding, Changhong Li, Xiaohui Wang · 2021 · Advances in clinical chemistry
- A distinct pattern of memory and attention deficiency in patients with depressionLuo, Lan-lan, Chen, Xin, Chai, Yan, Li, Jin-hong, Zhang, Mian, Zhang, Jian-ning · 2013 · Chinese Medical Journal
- β-amyloid oligomers and prion proteinGianluigi Forloni, Claudia Balducci · 2011 · Prion
- A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion proteinNadine S. Rösener, Lothar Gremer, Elke Reinartz, Anna König, Oleksandr Brener, Henrike Heise, Wolfgang Hoyer, Philipp Neudecker, Dieter Willbold · 2018 · Journal of Biological Chemistry
- Stability analysis of a steady state of a model describing Alzheimer’s disease and interactions with prion proteinsMohammed Helal, Angélique Igel‐Egalon, Abdelkader Lakmeche, Pauline Mazzocco, Angélique Perrillat-Mercerot, Laurent Pujo-Menjouet, Human Rezaei, Léon Matar Tine · 2018 · Journal of Mathematical Biology
- The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating BrainRosalina Gavı́n, Laia Lidón, Isidró Ferrer, José Antonio del Rı́o · 2020 · Cells
- The cellular prion protein beyond prion diseasesGiorgia Manni, Victoria Lewis, Matteo Senesi, Giovanni Spagnolli, Francesca Fallarino, Steven John Collins, Sophie Mouillet‐Richard, Emiliano Biasini · 2020 · Swiss Medical Weekly
- Impact of the Cellular Prion Protein on Amyloid-β and 3PO-Tau ProcessingMatthias Schmitz, Katharina Wulf, Sandra C. Signore, Walter Schulz‐Schaeffer, Pawel Kermer, Mathias Bähr, Fred Silvester Wouters, Saima Zafar, Inga Zerr · 2013 · Journal of Alzheimer s Disease
- State of aggregation2011 · Nature Neuroscience
- Sensing α‐Synuclein From the Outside via the Prion Protein: Implications for NeurodegenerationInês Caldeira Brás, Luísa Vaqueiro Lopes, Tiago F. Outeiro · 2018 · Movement Disorders
- Prion protein and prion disease at a glanceCaihong Zhu, Adriano Aguzzi · 2021 · Journal of Cell Science
- Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System DevelopmentSylvaine Huc-Brandt, Nelson Hieu, Thibaut Imberdis, Nicolas Cubedo, Michelle Silhol, Patricia L.A. Leighton, Thomas Domaschke, W. Ted Allison, Véronique Perrier, Mireille Rossel · 2014 · PLoS ONE
- Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different MechanismsJens Moreth, Katja S. Kroker, Daniel Schwanzar, Cathrin Schnack, Christine A. F. Von Arnim, Bastian Hengerer, Holger Rosenbrock, Lothar Kußmaul · 2013 · Biochemistry
- The Link of the Prion Protein with Ca2+ Metabolism and ROS Production, and the Possible Implication in Aβ ToxicityAgnese De Mario, Caterina Peggion, Maria Lina Massimino, Rosa Pia Norante, Alessandra Zulian, Alessandro Bertoli, Maria Catia Sorgato · 2019 · International Journal of Molecular Sciences
- Regulation of amyloid-β production by the prion proteinHeledd Jarosz-Griffiths, Isobel J. Whitehouse, Nigel M. Hooper · 2012 · Prion
- Possible role for Ca2+ in the pathophysiology of the prion protein?Caterina Peggion, Alessandro Bertoli, Maria Catia Sorgato · 2011 · BioFactors
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- Soluble Prion Protein Binds Isolated Low Molecular Weight Amyloid-β Oligomers Causing Cytotoxicity InhibitionThomas L. Williams, Jin-Kyu Choi, Krystyna A. Surewicz, Witold K. Surewicz · 2015 · ACS Chemical Neuroscience
- Preferential Recruitment of Conformationally Distinct Amyloid-β Oligomers by the Intrinsically Disordered Region of the Human Prion ProteinPriyanka Madhu, Samrat Mukhopadhyay · 2019 · ACS Chemical Neuroscience
- Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's diseaseNicole T. Watt, Heledd Jarosz-Griffiths, Nigel M. Hooper · 2014 · Frontiers in Cell and Developmental Biology
- Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic miceLara Ordóñez‐Gutiérrez, Juan María Torres, Rosalina Gavı́n, Marta Antón, Ana I. Arroba, Juan Carlos Espinosa, Cristina Vergara, José Antonio del Rı́o, Francisco G. Wandosell · 2013 · Neurobiology of Aging
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- Promising anti-amyloid behavior of cationic pyridylphenylene dendrimers: Role of structural features and mechanism of actionSvetlana A. Sorokina, Yulia Yu. Stroylova, Sofia A. Tishina, Zinaida B. Shifrina, Vladimir I. Muronetz · 2019 · European Polymer Journal
- Quantum dots and prion proteinsPavlína Šobrová, Iva Blažková, Jana Chomoucká, Jana Drbohlavová, Markéta Vaculovičová, Pavel Kopel, Jaromír Hubálek, René Kizek, Vojtěch Adam · 2013 · Prion
- New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion proteinRyan R. Myers, Jonatan Sanchez-Garcia, Daniel C. Levings, Richard G. Melvin, Pedro Fernández-Fúnez · 2022 · Disease Models & Mechanisms
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- Accumulation of Prion and Abnormal Prion Protein Induces Hyperphosphorylation of α-Synuclein in the Brain Tissues from Prion Diseases and in the Cultured CellsDongdong Chen, Liping Gao, Yue-Zhang Wu, Chen Jia, Chao Hu, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong · 2021 · ACS Chemical Neuroscience