The prion protein as a receptor for amyloid-β

Cited by (253)

Items 101–200 of 253

  1. Prion Protein: The Molecule of Many Forms and Faces
    Valerija Kovač, Vladka Čurin Šerbec · 2022 · International Journal of Molecular Sciences
  2. Cellular Prion Protein as a Therapeutic Target in Alzheimer's Disease
    Juha Laurén · 2013 · Journal of Alzheimer s Disease
  3. The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells
    Elena De Cecco, Luigi Celauro, Silvia Vanni, Micaela Grandolfo, Edoardo Bistaffa, Fabio Moda, Adriano Aguzzi, Giuseppe Legname · 2020 · Journal of Neurochemistry
  4. Mechanisms of prion-induced neurodegeneration
    Paula Saá, David A. Harris, Larisa Červen̆áková · 2016 · Expert Reviews in Molecular Medicine
  5. Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity
    Despoina Goniotaki, Asvin KK Lakkaraju, Amulya Nidhi Shrivastava, Pamela Bakirci, Silvia Sorce, Assunta Senatore, Rajlakshmi Marpakwar, Simone Hornemann, Fabrizio Gasparini, Antoine Triller et al. · 2017 · PLoS Pathogens
  6. Cellular Prion Protein Regulates Its Own α-Cleavage through ADAM8 in Skeletal Muscle
    Jingjing Liang, Wei Wang, Debra Sorensen, Sarah J. Medina, Sergei A. Ilchenko, Janna Kiselar, Witold K. Surewicz, Stephanie A. Booth, Qingzhong Kong · 2012 · Journal of Biological Chemistry
  7. Allosteric function and dysfunction of the prion protein
    Rafael Linden, Yraima Cordeiro, Luís Maurício T. R. Lima · 2011 · Cellular and Molecular Life Sciences
  8. Single‐Molecule Imaging Reveals that Small Amyloid‐β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC)
    Kristina A. Ganzinger, Priyanka S. Narayan, Seema Qamar, Laura Weimann, Rohan T. Ranasinghe, Adriano Aguzzi, Christopher Martin Dobson, James T. McColl, Peter St George‐Hyslop, David Klenerman · 2014 · ChemBioChem
  9. Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease
    Jonah J. Scott-McKean, Krystyna A. Surewicz, Jin-Kyu Choi, Vernon A. Ruffin, Ahlam Salameh, Krzysztof Nieznański, Alberto C. S. Costa, Witold K. Surewicz · 2016 · Neurobiology of Disease
  10. HLA in Alzheimer’s Disease: Genetic Association and Possible Pathogenic Roles
    Zixuan Wang, Qi Wan, Ang Xing · 2020 · NeuroMolecular Medicine
  11. Early Molecular Changes in Alzheimer Disease: Can We Catch the Disease in its Presymptomatic Phase?
    Kerstin T.S. Wirz, Stella Keitel, Dick Frans Swaab, Joost Verhaagen, Koen Bossers · 2013 · Journal of Alzheimer s Disease
  12. Protein Co-Aggregation Related to Amyloids: Methods of Investigation, Diversity, and Classification
    Stanislav A. Bondarev, Kirill S. Antonets, Andrey V. Kajava, Anton A. Nizhnikov, Galina A. Zhouravleva · 2018 · International Journal of Molecular Sciences
  13. The cellular prion protein (PrPC) as neuronal receptor for α-synuclein
    Laura Urrea, Isidró Ferrer, Rosalina Gavı́n, José Antonio del Rı́o · 2017 · Prion
  14. Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer's disease
    Elena Anahí Bignante, Florencia Heredia, Gerardo A. Morfini, Alfredo Lorenzo · 2013 · Neurobiology of Aging
  15. Aβ induces its own prion protein N-terminal fragment (PrPN1)–mediated neutralization in amorphous aggregates
    Maxime Béland, Mikaël Bédard, Guillaume Tremblay, Pierre Lavigne, Xavier Roucou · 2014 · Neurobiology of Aging
  16. Regulation of spine structural plasticity by Arc/Arg3.1
    Thomas M. Newpher, Scott C. Harris, Jasmine Pringle, Colleen Hamilton, Scott H. Soderling · 2017 · Seminars in Cell and Developmental Biology
  17. Cellular prion protein targets amyloid-β fibril ends via its C-terminal domain to prevent elongation
    Erin Bove‐Fenderson, Ryo Urano, John E. Straub, David A. Harris · 2017 · Journal of Biological Chemistry
  18. The Role of Exosomes in Stemness and Neurodegenerative Diseases—Chemoresistant-Cancer Therapeutics and Phytochemicals
    Narasimha Murthy Beeraka, Shalini H. Doreswamy, Surya Prabha Sadhu, Asha Srinivasan, Rajeswara Rao Pragada, SubbaRao V. Madhunapantula, Gjumrakch Aliev · 2020 · International Journal of Molecular Sciences
  19. Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay
    Emmanuel Risse, Andrew J. Nicoll, William A. Taylor, Daniel Wright, Mayank Badoni, Xiaofan Yang, Mark A. Farrow, John Collinge · 2015 · Journal of Biological Chemistry
  20. Prion protein and aging
    Lisa Gasperini, Giuseppe Legname · 2014 · Frontiers in Cell and Developmental Biology
  21. Structural details of amyloid β oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy
    Anna S. König, Nadine S. Rösener, Lothar Gremer, Markus Tusche, Daniel Flender, Elke Reinartz, Wolfgang Hoyer, Philipp Neudecker, Dieter Willbold, Henrike Heise · 2021 · Journal of Biological Chemistry
  22. Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids
    Ron Balczon, Kyle Adam Morrow, Chun Zhou, B. Douglas Edmonds, Mikhail F. ALEXEYEV, Jean‐François Pittet, Brant M. Wagener, Stephen A. Moser, Silas J. Leavesley, Xiang‐ming Zha et al. · 2017 · The FASEB Journal
  23. The role of the prion protein in the internalization of α-synuclein amyloids
    Elena De Cecco, Giuseppe Legname · 2018 · Prion
  24. Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease
    Nadine D. Younan, Ko‐Fan Chen, Ruth‐Sarah Rose, Damian C. Crowther, John H. Viles · 2018 · Journal of Biological Chemistry
  25. A ‘danse macabre’: tau and F yn in STEP with amyloid beta to facilitate induction of synaptic depression and excitotoxicity
    Jannic Boehm · 2013 · European Journal of Neuroscience
  26. Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease
    Valeriy G. Ostapchenko, Flávio H. Beraldo, André Luiz Sena Guimarães, Sanju Mishra, Mónica S. Guzmán, Jue Fan, Vilma Regina Martins, Vânia F. Prado, Marco A. M. Prado · 2013 · Journal of Neurochemistry
  27. Modeling Alzheimer’s disease with human iPS cells: advancements, lessons, and applications
    Sofia Essayan-Perez, Bo Zhou, Amber M. Nabet, Marius Wernig, Yu‐Wen Alvin Huang · 2019 · Neurobiology of Disease
  28. Characterizing affinity epitopes between prion protein and β-amyloid using an epitope mapping immunoassay
    Mino Kang, Su Yeon Kim, Seong Soo A. An, Young Ran Ju · 2013 · Experimental & Molecular Medicine
  29. Beta-Amyloid Peptides Enhance the Proliferative Response of Activated CD4+CD28+ Lymphocytes from Alzheimer Disease Patients and from Healthy Elderly
    Agnieszka Jóźwik, Jerzy Landowski, Leszek Bidzan, Tamàs Fülöp, Ewa Bryl, Jacek Maciej Witkowski · 2012 · PLoS ONE
  30. Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer’s-Associated Aβ Oligomers
    Kyle C. Wilcox, Matthew R. Marunde, Aditi Das, Pauline T. Velasco, Benjamin D. Kuhns, Michael Thomas Marty, Jiang Haoming, Chi-Hao Luan, Stephen G. Sligar, William L. Klein · 2015 · PLoS ONE
  31. Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor
    Aadilah Omar, Katarina Jovanovic, Bianca Da Costa Dias, Danielle Gonsalves, Kiashanee Moodley, R. J. Caveney, Vusi Gordon Mbazima, Stefan F. T. Weiss · 2010 · Expert Opinion on Therapeutic Patents
  32. Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity
    Miyamoto, Takashi, Kim, Daniel, Knox, Joseph A., Johnson, Erik, Mucke, Lennart · 2016 · Journal of Biological Chemistry
  33. Neuroprotective and Neurotoxic Signaling by the Prion Protein
    Ulrike K. Resenberger, Konstanze F. Winklhofer, Jörg Tatzelt · 2011 · Topics in current chemistry
  34. Five Questions on Prion Diseases
    Adriano Aguzzi, Caihong Zhu · 2012 · PLoS Pathogens
  35. Neurogranin restores amyloid β-mediated synaptic transmission and long-term potentiation deficits
    Kanwardeep S. Kaleka, Nashaat Zakaria Gerges · 2015 · Experimental Neurology
  36. Prion Protein Interactome: Identifying Novel Targets in Slowly and Rapidly Progressive Forms of Alzheimer’s Disease
    Saima Zafar, Mohsin Shafiq, Neelam Younas, Matthias Schmitz, Isidró Ferrer, Inga Zerr · 2017 · Journal of Alzheimer s Disease
  37. Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils
    Rafael Meyer Mariante, Alberto Nóbrega, Rodrigo A. P. Martins, Rômulo B. Areal, Maria Bellio, Rafael Linden · 2012 · Journal of Biological Chemistry
  38. Aβ Inhibition of Ionic Conductance in Mouse Basal Forebrain Neurons Is Dependent upon the Cellular Prion Protein PrPC
    Kwai A. Alier, Li Ma, Jing Yang, David A. Westaway, Jack H. Jhamandas · 2011 · Journal of Neuroscience
  39. Alzheimer's Disease and Prion Protein
    Jiayi Zhou · 2013 · Intractable & Rare Diseases Research
  40. Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via the Fyn Pathway
    Rong-Jie Chen, Wei-Wei Chang, Yu‐Chun Lin, Pei‐Lin Cheng, Yun‐Ru Chen · 2013 · ACS Chemical Neuroscience
  41. Molecular Pathogenesis and Interventional Strategies for Alzheimer’s Disease: Promises and Pitfalls
    Shashikala Bhute, Deepaneeta Sarmah, Aishika Datta, Pallavi Rane, Amit Shard, Avirag Goswami, Anupom Borah, Kiran Kalia, Kunjan R. Dave, Pallab Bhattacharya · 2020 · ACS Pharmacology & Translational Science
  42. Breaking the Code of Amyloid- β Oligomers
    Sylvain Lesné · 2013 · International Journal of Cell Biology
  43. Prion protein and its role in signal transduction
    Alessandro Didonna · 2013 · Cellular & Molecular Biology Letters
  44. Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1
    Pravas Kumar Baral, Barbara Wieland, Mridula Swayampakula, Magdalini Polymenidou, Muhammad Hafiz Rahman, Nat N. V. Kav, Adriano Aguzzi, Michael N.G. James · 2012 · Acta Crystallographica Section D Biological Crystallography
  45. Prion protein oligomer and its neurotoxicity
    Pei Huang, Fulin Lian, Yi Wen, Chenyun Guo, Donghai Lin · 2013 · Acta Biochimica et Biophysica Sinica
  46. LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer’s Disease
    Emma C. Pinnock, Katarina Jovanovic, Maxine G. Pinto, Eloise Ferreira, Bianca Da Costa Dias, Clement Brian Penny, Stefan H.J. Knackmuss, Uwe Reusch, Melvyn Little, Hermann M. Schätzl et al. · 2015 · Journal of Alzheimer s Disease
  47. Role of cellular prion protein in interneuronal amyloid transmission
    José Antonio del Rı́o, Isidró Ferrer, Rosalina Gavı́n · 2018 · Progress in Neurobiology
  48. Insoluble cellular prion protein and its association with prion and Alzheimer diseases
    Wen‐Quan Zou, Xiaochen Zhou, Jue Yuan, Xiangzhu Xiao · 2011 · Prion
  49. Cellular Prion Protein Mediates Toxic Signaling of Amyloid Beta
    Ulrike K. Resenberger, Konstanze F. Winklhofer, Jörg Tatzelt · 2011 · Neurodegenerative Diseases
  50. On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseases
    Giuseppe Legname, Carlo Scialò · 2020 · Prion
  51. Aß Pathology and Neuron–Glia Interactions: A Synaptocentric View
    Christiaan F. M. Huffels, Jinte Middeldorp, Elly M. Hol · 2022 · Neurochemical Research
  52. Advances in fluorescent probes for detection and imaging of amyloid-β peptides in Alzheimer's disease
    Yunhua Zhang, Cen Ding, Changhong Li, Xiaohui Wang · 2021 · Advances in clinical chemistry
  53. A distinct pattern of memory and attention deficiency in patients with depression
    Luo, Lan-lan, Chen, Xin, Chai, Yan, Li, Jin-hong, Zhang, Mian, Zhang, Jian-ning · 2013 · Chinese Medical Journal
  54. β-amyloid oligomers and prion protein
    Gianluigi Forloni, Claudia Balducci · 2011 · Prion
  55. A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein
    Nadine S. Rösener, Lothar Gremer, Elke Reinartz, Anna König, Oleksandr Brener, Henrike Heise, Wolfgang Hoyer, Philipp Neudecker, Dieter Willbold · 2018 · Journal of Biological Chemistry
  56. Stability analysis of a steady state of a model describing Alzheimer’s disease and interactions with prion proteins
    Mohammed Helal, Angélique Igel‐Egalon, Abdelkader Lakmeche, Pauline Mazzocco, Angélique Perrillat-Mercerot, Laurent Pujo-Menjouet, Human Rezaei, Léon Matar Tine · 2018 · Journal of Mathematical Biology
  57. The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain
    Rosalina Gavı́n, Laia Lidón, Isidró Ferrer, José Antonio del Rı́o · 2020 · Cells
  58. The cellular prion protein beyond prion diseases
    Giorgia Manni, Victoria Lewis, Matteo Senesi, Giovanni Spagnolli, Francesca Fallarino, Steven John Collins, Sophie Mouillet‐Richard, Emiliano Biasini · 2020 · Swiss Medical Weekly
  59. Impact of the Cellular Prion Protein on Amyloid-β and 3PO-Tau Processing
    Matthias Schmitz, Katharina Wulf, Sandra C. Signore, Walter Schulz‐Schaeffer, Pawel Kermer, Mathias Bähr, Fred Silvester Wouters, Saima Zafar, Inga Zerr · 2013 · Journal of Alzheimer s Disease
  60. State of aggregation
    2011 · Nature Neuroscience
  61. Sensing α‐Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration
    Inês Caldeira Brás, Luísa Vaqueiro Lopes, Tiago F. Outeiro · 2018 · Movement Disorders
  62. Prion protein and prion disease at a glance
    Caihong Zhu, Adriano Aguzzi · 2021 · Journal of Cell Science
  63. Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development
    Sylvaine Huc-Brandt, Nelson Hieu, Thibaut Imberdis, Nicolas Cubedo, Michelle Silhol, Patricia L.A. Leighton, Thomas Domaschke, W. Ted Allison, Véronique Perrier, Mireille Rossel · 2014 · PLoS ONE
  64. Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different Mechanisms
    Jens Moreth, Katja S. Kroker, Daniel Schwanzar, Cathrin Schnack, Christine A. F. Von Arnim, Bastian Hengerer, Holger Rosenbrock, Lothar Kußmaul · 2013 · Biochemistry
  65. The Link of the Prion Protein with Ca2+ Metabolism and ROS Production, and the Possible Implication in Aβ Toxicity
    Agnese De Mario, Caterina Peggion, Maria Lina Massimino, Rosa Pia Norante, Alessandra Zulian, Alessandro Bertoli, Maria Catia Sorgato · 2019 · International Journal of Molecular Sciences
  66. Regulation of amyloid-β production by the prion protein
    Heledd Jarosz-Griffiths, Isobel J. Whitehouse, Nigel M. Hooper · 2012 · Prion
  67. Possible role for Ca2+ in the pathophysiology of the prion protein?
    Caterina Peggion, Alessandro Bertoli, Maria Catia Sorgato · 2011 · BioFactors
  68. Hijacking PrPc-dependent signal transduction: when prions impair Aβ clearance
    Julia Hernandez-Rapp, Severine Martin‐Lannerée, Théo Z. Hirsch, Jean‐Marie Launay, Sophie Mouillet‐Richard · 2014 · Frontiers in Aging Neuroscience
  69. The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts
    Izabella Grimaldi, Felipe Saceanu Leser, José Marcos Janeiro, Bárbara Gomes da Rosa, Ana Clara Campanelli, Luciana Ferreira Romão, Flávia Regina Souza Lima · 2022 · Journal of Molecular Medicine
  70. Soluble Prion Protein Binds Isolated Low Molecular Weight Amyloid-β Oligomers Causing Cytotoxicity Inhibition
    Thomas L. Williams, Jin-Kyu Choi, Krystyna A. Surewicz, Witold K. Surewicz · 2015 · ACS Chemical Neuroscience
  71. Preferential Recruitment of Conformationally Distinct Amyloid-β Oligomers by the Intrinsically Disordered Region of the Human Prion Protein
    Priyanka Madhu, Samrat Mukhopadhyay · 2019 · ACS Chemical Neuroscience
  72. Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease
    Nicole T. Watt, Heledd Jarosz-Griffiths, Nigel M. Hooper · 2014 · Frontiers in Cell and Developmental Biology
  73. Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice
    Lara Ordóñez‐Gutiérrez, Juan María Torres, Rosalina Gavı́n, Marta Antón, Ana I. Arroba, Juan Carlos Espinosa, Cristina Vergara, José Antonio del Rı́o, Francisco G. Wandosell · 2013 · Neurobiology of Aging
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    Nicholas Verity, Giovanna R. Mallucci · 2010 · Biochemical Journal
  76. Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
    Akikazu Sakudo, Takashi Onodera · 2015 · Frontiers in Cell and Developmental Biology
  77. CSF prion protein concentration and cognition in patients with Alzheimer disease
    Christian Schmidt, Svetlana Artjomova, Martin Hoeschel, Inga Zerr · 2013 · Prion
  78. Soluble Aβ aggregates can inhibit prion propagation
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  79. Association of prion protein with cognitive functioning in humans
    Lutz Philipp Breitling, Heiko Müller, Christa Stegmaier, Matthias Kliegel, Hermann Brenner · 2012 · Experimental Gerontology
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    Angela da Silva Correia, Matthias Schmitz, Anna‐Lisa Fischer, Susana Correia, Franco L. Simonetti, Gesine Saher, Roberto Goya‐Maldonado, Amandeep Singh Arora, André Fischer, Tiago F. Outeiro et al. · 2024 · Alzheimer s & Dementia
  81. Neuroprotective effect and potential of cellular prion protein and its cleavage products for treatment of neurodegenerative disorders part I. a literature review
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  84. The neurodegeneration in Alzheimer disease and the prion protein
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    Ádám Annus, Anett Csáti, László Vécsei · 2016 · Clinical Neurology and Neurosurgery
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  88. Taking advantage of physiological proteolytic processing of the prion protein for a therapeutic perspective in prion and Alzheimer diseases
    Maxime Béland, Xavier Roucou · 2013 · Prion
  89. “Dual Disease” TgAD/GSS mice exhibit enhanced Alzheimer’s disease pathology and reveal PrPC-dependent secretion of Aβ
    Kefeng Qin, Lili Zhao, Crystal Gregory, Ani Solanki, James A. Mastrianni · 2019 · Scientific Reports
  90. Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
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  91. Cellular prion protein and Alzheimer disease
    Wataru Kudo, Robert B. Petersen, Hyoung‐gon Lee · 2013 · Prion
  92. Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in
    Marius Chiasseu, Arman Fesharaki‐Zadeh, Takashi Saito, Takaomi C. Saido, Stephen M. Strittmatter · 2020 · Neurobiology of Disease
  93. Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer’s disease
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  94. Role of amyloid β protein receptors in mediating synaptic plasticity
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  96. Promising anti-amyloid behavior of cationic pyridylphenylene dendrimers: Role of structural features and mechanism of action
    Svetlana A. Sorokina, Yulia Yu. Stroylova, Sofia A. Tishina, Zinaida B. Shifrina, Vladimir I. Muronetz · 2019 · European Polymer Journal
  97. Quantum dots and prion proteins
    Pavlína Šobrová, Iva Blažková, Jana Chomoucká, Jana Drbohlavová, Markéta Vaculovičová, Pavel Kopel, Jaromír Hubálek, René Kizek, Vojtěch Adam · 2013 · Prion
  98. New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion protein
    Ryan R. Myers, Jonatan Sanchez-Garcia, Daniel C. Levings, Richard G. Melvin, Pedro Fernández-Fúnez · 2022 · Disease Models & Mechanisms
  99. Laboratory activities involving transmissible spongiform encephalopathy causing agents
    Amaya Leunda, Bernadette Van Vaerenbergh, Aline Baldo, S. Roels, Philippe Herman · 2013 · Prion
  100. Accumulation of Prion and Abnormal Prion Protein Induces Hyperphosphorylation of α-Synuclein in the Brain Tissues from Prion Diseases and in the Cultured Cells
    Dongdong Chen, Liping Gao, Yue-Zhang Wu, Chen Jia, Chao Hu, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong · 2021 · ACS Chemical Neuroscience