The prion protein as a receptor for amyloid-β

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

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APP Processing and Synaptic Function

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Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

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Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

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Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models

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AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss

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Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics

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Aβ toxicity in Alzheimer’s disease: globular oligomers (ADDLs) as new vaccine and drug targets

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Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein

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Roles of stargazin and phosphorylation in the control of AMPA receptor subcellular distribution

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Amyloid Beta: Structure, Biology and Structure-Based Therapeutic Development

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Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

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The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

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Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

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Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

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The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

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Synapses and Alzheimer's Disease

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Human LilrB2 Is a β-Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer’s Model

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Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

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Soluble Aβ oligomer production and toxicity

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Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

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Prions, prionoids and protein misfolding disorders

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Alzheimer's disease: synapses gone cold

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Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

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The biological function of the cellular prion protein: an update

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A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer’s brain

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Protein phosphorylation in neurodegeneration: friend or foe?

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Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

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Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N -methyl- d -aspartate receptors

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Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTP<i>In Vivo</i>Is Prevented by Immunotargeting Cellular Prion Protein

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Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids

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Lipid Rafts: Linking Alzheimer′s Amyloid‐βProduction, Aggregation, and Toxicity at Neuronal Membranes

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Fyn kinase inhibition as a novel therapy for Alzheimer’s disease

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Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

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Membrane Trafficking Pathways in Alzheimer 's Disease

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An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicity in Vivo

Fluharty, B. R., Biasini, E., Stravalaci, M., Sclip, A., Diomede, L., Balducci, C., Vitola, P. L., Messa, M., Colombo, L., Forloni, G., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.423954 · Cited by 183 · see citing works

Prion protein at the crossroads of physiology and disease

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Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse

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Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer’s Disease

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Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta‐mediated neurotoxicity

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N ‐Methyl‐ d ‐aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid‐β peptide oligomers

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The Dual Role of Glutamatergic Neurotransmission in Alzheimer’s Disease: From Pathophysiology to Pharmacotherapy

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Routes, destinations and delays: recent advances in AMPA receptor trafficking

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Aβ Oligomer-Induced Synapse Degeneration in Alzheimer’s Disease

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The Toxicity of Amyloid ß Oligomers

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PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins

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Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

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The immunobiology of prion diseases

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Cell Biology of Prions and Prionoids: A Status Report

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Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer’s disease

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Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models

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FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease

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α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication

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Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminili γ1 chain

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Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

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Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

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Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death

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Copper‐dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders

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The dendritic hypothesis for Alzheimer's disease pathophysiology

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Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease

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Amyloid-<i>β</i>-Induced Dysregulation of AMPA Receptor Trafficking

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Role of α7 Nicotinic Acetylcholine Receptor in Calcium Signaling Induced by Prion Protein Interaction with Stress-inducible Protein 1

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Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus

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Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

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The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers

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Transthyretin and the brain re-visited: Is neuronal synthesis of transthyretin protective in Alzheimer's disease?

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Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances

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Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities

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Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer’s Disease

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The function of the cellular prion protein in health and disease

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Targeting Synaptic Dysfunction in Alzheimer’s Disease Therapy

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α-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid β (Aβ)-associated Cell Death

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Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions

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Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery

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Proteolytic processing of the prion protein in health and disease.

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Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers

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Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers

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Therapeutic potential of mGluR5 targeting in Alzheimer's disease

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Synaptic Cell Adhesion Molecules in Alzheimer’s Disease

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Cellular prion protein as a receptor for amyloid-β oligomers in Alzheimer's disease

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Copper imbalance in Alzheimer’s disease: Convergence of the chemistry and the clinic

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Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins

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Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTP<i>In Vivo</i>Is Prevented by Immunotargeting Cellular Prion Protein

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