Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
Oberst, Andrew, Dillon, Christopher P., Weinlich, Ricardo, McCormick, Laura L., Fitzgerald, Patrick, Pop, Cristina, Hakem, Razq, Salvesen, Guy S., Green, Douglas R.·2011·Nature
Cited by (999)
Items 701–800 of 999
- Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboesMohammad Arifuzzaman, W.X. Gladys Ang, Hae Woong Choi, Matthew L. Nilles, Ashley L. St. John, Soman N. Abraham · 2018 · JCI Insight
- Measuring Apoptosis: Caspase Inhibitors and Activity AssaysGavin Peter McStay, Douglas R. Green · 2014 · Cold Spring Harbor Protocols
- miRNA expression profiling regulates necroptotic cell death in hepatocellular carcinomaMaria Visalli, Marcello Bartolotta, Francesca Polito, Rosaria Oteri, Adalberto Barbera, Roberto Arrigo, Rosa María Di Giorgio, Giuseppe Navarra, M. Aguennouz · 2018 · International Journal of Oncology
- TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3John P. Dowling, Mohamed Yaseen Alsabbagh, Christina Del Casale, Zheng-gang Liu, Jianke Zhang · 2019 · Nature Communications
- A Two-Cell Model for IL-1β Release Mediated by Death-Receptor SignalingCarlos A. Donado, Anh Cao, Daimon P. Simmons, Ben A. Croker, Patrick J. Brennan, Michael B. Brenner · 2020 · Cell Reports
- Prevention of Cellular Suicide by CytomegalovirusesPatricia M. Fliss, Wolfram Brune · 2012 · Viruses
- Fight or flightBen A. Croker, John Silke, Motti Gerlic · 2015 · Current Opinion in Hematology
- An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisionsMarie Oliver Metzig, Ying Tang, Simon A. Mitchell, Brooks E. Taylor, Robert Foreman, Roy Wollman, Alexander Hoffmann · 2020 · Molecular Systems Biology
- Sweet modification and regulation of death receptor signalling pathwayKenta Moriwaki, Francis Ka-Ming Chan, Eiji Miyoshi · 2021 · The Journal of Biochemistry
- Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady stateFarzaneh Ghazavi, Jelle Huysentruyt, Jordy De Coninck, Stephanie Kourula, Sofie Martens, Behrouz Hassannia, Tim Wartewig, Tatyana Divert, Ria Roelandt, Bastian Popper et al. · 2022 · Proceedings of the National Academy of Sciences
- Role of necroptosis in airflow limitation in chronic obstructive pulmonary disease: focus on small-airway disease and emphysemaChanjing Liu, Peijun Li, Jiejiao Zheng, Yingqi Wang, Weibing Wu, Xiaodan Liu · 2022 · Cell Death Discovery
- Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cellsYung‐Hsuan Wu, Shu-Ting Mo, I‐Ting Chen, Fu‐Yi Hsieh, Shie-Liang Edmond Hsieh, Jinake Zhang, Ming‐Zong Lai · 2022 · Science Advances
- The Role of Sex Differences in Autophagy in the Heart During Coxsackievirus B3-Induced MyocarditisAndreas Koenig, Adam Sateriale, Ralph C. Budd, Sally Ann Huber, Iwona A. Buskiewicz · 2013 · Journal of Cardiovascular Translational Research
- MLN 4924 sensitizes monocytes and maturing dendritic cells for TNF ‐dependent and ‐independent necroptosisMohamed El‐Mesery, Axel Seher, Thorsten Stühmer, Daniela Siegmund, Harald Wajant · 2014 · British Journal of Pharmacology
- Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration modelEdel T. Kavanagh, Miguel Ángel Burguillos, Alejandro Carrillo-Jiménez, Maria José Oliva-Martín, Martiniano Santiago, Johanna Rodhe, Bertrand Joseph, Jose Luis Venero · 2015 · Aging
- Tea (Camellia sinensis) infusions ameliorate cancer in 4TI metastatic breast cancer modelKarori Mbuthia, Paul O. Mireji, Raphael Muchangi Ngure, Francesca Stomeo, Martina Kyallo, Richard Chalo Muoki, Francis Nyamu Wachira · 2017 · BMC Complementary and Alternative Medicine
- Inhibition of mitochondrial ROS-mediated necroptosis by Dendrobium nobile Lindl. alkaloids in carbon tetrachloride induced acute liver injurySiting Xian, Yonggang Yang, Nan Nan, Xiaolong Fu, Jingshan Shi, Qin Wu, Shaoyu Zhou · 2024 · Journal of Ethnopharmacology
- Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosisChao‐Yu Yang, Chia-I Lien, Yi-Chun Tseng, Yi-Fan Tu, Arek Kulczyk, Yen-Chen Lu, Yin-Ting Wang, Tsung-Wei Su, Li-Chung Hsu, Yu-Chih Lo et al. · 2024 · Nature Communications
- Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory diseaseJohn R. Lukens, Thirumala‐Devi Kanneganti · 2014 · Seminars in Immunopathology
- Caspases orchestrate microglia instrumental functionsXianli Shen, Jose Luis Venero, Bertrand Joseph, Miguel Ángel Burguillos · 2018 · Progress in Neurobiology
- Targeting RIP Kinases in Chronic Inflammatory DiseaseMary Speir, Tirta Mario Djajawi, Stephanie A. Conos, Hazel Tye, Kate E. Lawlor · 2021 · Biomolecules
- Long Noncoding RNA MIAT Regulates Hyperosmotic Stress-Induced Corneal Epithelial Cell Injury via Inhibiting the Caspase-1-Dependent Pyroptosis and Apoptosis in Dry Eye DiseaseJinjian Li, Kun Yang, Xinghui Pan, Hui Chin Peng, Chenting Hou, Jie Xiao, Qing Wang · 2022 · Journal of Inflammation Research
- CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complexChiel Maas, Jacqueline Maria Tromp, Jacoline van Laar, Rachel Thijssen, J A Elias, Anna Malara, Anja Krippner‐Heidenreich, John Silke, Marinus H. J. van Oers, Eric Eldering · 2013 · Cell Death and Disease
- NFκB and ubiquitination: partners in disarming RIPK1-mediated cell deathMarie Anne O’Donnell, Adrian T. Ting · 2012 · Immunologic Research
- PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD PatientsFelipe Salech, Daniela P. Ponce, Carol D. SanMartín, Nicole K. Rogers, Carlos Chacón, Mauricio Henríquez, María Isabel Behrens · 2017 · Frontiers in Aging Neuroscience
- Cell-Cycle Cross Talk with Caspases and Their SubstratesPatrick F. Connolly, Irmina García-Carpio, Andreas Villunger · 2019 · Cold Spring Harbor Perspectives in Biology
- N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammationAlexander D. Gitlin, Allie Maltzman, Yuzuka Kanno, Klaus Heger, Rohit Reja, Alexander F. Schubert, Linsey J. Wierciszewski, Homer Pantua, Sharookh B. Kapadia, Seth F. Harris et al. · 2024 · Immunity
- Emerging regulated cell death mechanisms in bone remodeling: decoding ferroptosis, cuproptosis, disulfidptosis, and PANoptosis as therapeutic targets for skeletal disordersHanchang Hu, Zhen-Yu Zhang, Zi -Xin Luo, Huibo Ti, Jun‐Jie Wu, Hao Nie, Zheng‐Dong Yuan, Xian Liang Wu, Ke-Yue Zhang, Shuwen Shi et al. · 2025 · Cell Death Discovery
- Classification, Scoring, and Quantification of Cell Death in Tissue SectionsLaura J. Janke, Jerrold Michael Ward, Peter Vogel · 2018 · Veterinary Pathology
- Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventionsMaria Jose Yañez, Tamara Marín, Elisa Balboa, Andrés D. Klein, Alejandra R. Alvarez, Silvana Zanlungo · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim−/− miceToshiyuki Bohgaki, Julien Mozo, Leonardo Salmena, Elzbieta Matysiak‐Zablocki, Miyuki Bohgaki, Otto H. Sanchez, Andreas Strasser, Anne Hakem, Razqallah Hakem · 2011 · The Journal of Cell Biology
- Deciphering the Molecular Nexus: An In-Depth Review of Mitochondrial Pathways and Their Role in Cell Death CrosstalkYumeng Li, Madiha Rasheed, Jingkai Liu, Zixuan Chen, Yulin Deng · 2024 · Cells
- Regulation of RIPK1 Phosphorylation: Implications for Inflammation, Cell Death, and Therapeutic InterventionsJingchun Du, Zhigao Wang · 2024 · Biomedicines
- Commensal Microbiota Are Required for Systemic Inflammation Triggered by Necrotic Dendritic CellsJennifer A. Young, Tina H. He, Boris Reizis, Astar Winoto · 2013 · Cell Reports
- Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progressionJiao Li, Jiahong Shi, Yue Pan, Yunhe Zhao, Fuhua Yan, Houxuan Li, Lang Lei · 2019 · Scientific Reports
- Crucial Roles of the RIP Homotypic Interaction Motifs of RIPK3 in RIPK1-Dependent Cell Death and Lymphoproliferative DiseaseHaiwei Zhang, Xiaoming Li, Ming Li, Fang Li, Feng Li, L Wang, Yue Zhang, Yue Zhang, Yan Luo, Hui Wang et al. · 2020 · Cell Reports
- Role of programmed necrosis and cell death in intestinal inflammationMaryse Dagenais, Todd Douglas, Maya Saleh · 2014 · Current Opinion in Gastroenterology
- Regulated Cell Death Signaling Pathways and Marine Natural Products That Target ThemEsther A. Guzmán · 2019 · Marine Drugs
- Interferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activityJiancheng Chen, Shunsuke Kuroki, Masataka Someda, Shin Yonehara · 2019 · Journal of Biological Chemistry
- The flick of a switch: which death program to choose?Peter Vandenabeele, Gerry Melino · 2012 · Cell Death and Differentiation
- Single-Cell Microgel Encapsulation Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Treating Intervertebral Disc Degeneration via Inhibiting PyroptosisGuanrui Huang, Haotian Shen, Kaiwang Xu, Yifan Shen, Jiale Jin, Guangyu Chu, Hongyuan Xing, Zhiyun Feng, Yue Wang · 2024 · Research
- Mechanisms of Acute Kidney Injury–Chronic Kidney Disease Transition: Unraveling Maladaptive Repair and Therapeutic OpportunitiesDongxue Xu, Xiaoyu Zhang, Jingjing Pang, Yiming Li, Zhiyong Peng · 2025 · Biomolecules
- Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal IleitisRyodai Shindo, Masaki Ohmuraya, Sachiko Komazawa‐Sakon, Sanae Miyake, Yutaka Deguchi, Soh Yamazaki, Takashi Nishina, Takayuki Yoshimoto, Soichiro Kakuta, Masato Koike et al. · 2019 · iScience
- Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucomaXiangjun Yang, Qun Zeng, Gülgün Tezel · 2021 · Neurobiology of Disease
- Contribution of cell death signaling to blood vessel formationNathalie Tisch, Carmen Ruiz de Almodóvar · 2021 · Cellular and Molecular Life Sciences
- An overview of programmed cell death: Apoptosis and pyroptosis—Mechanisms, differences, and significance in organism physiology and pathophysiologySzymon Kowalski, Julia Karska, Zofia Łapińska, Bartosz Hetnał, Jolanta Saczko, Julita Kulbacka · 2023 · Journal of Cellular Biochemistry
- Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK 1Scott J. Justus, Adrian T. Ting · 2015 · Immunological Reviews
- Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP)Mehdi Baratchian, Christopher A. Davis, Akira Shimizu, David Escors, Claire Bagnéris, Tracey E. Barrett, Mary K. Collins · 2016 · Journal of Biological Chemistry
- Dichotomy between Receptor-Interacting Protein 1– and Receptor-Interacting Protein 3–Mediated Necroptosis in Experimental PancreatitisJianghong Wu, Tunike Mulatibieke, Jianbo Ni, Xiao Han, Бин Ли, Yue Zeng, Rong Wan, Xingpeng Wang, Guoyong Hu · 2017 · American Journal Of Pathology
- A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic FungusNatália Ketelut-Carneiro, Sreya Ghosh, Stuart M. Levitz, Katherine A. Fitzgerald, João S. Silva · 2017 · The Journal of Infectious Diseases
- Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1Yuanxin Yang, Jian Zhang, Mingming Lv, Na Cui, Bing Shan, Qi Sun, Lingjie Yan, Mengmeng Zhang, Chengyu Zou, Junying Yuan et al. · 2024 · Nature Cell Biology
- Cell death signaling and immune regulation: new perspectives on targeted therapy for sepsisHuang Wu, Jiale Cui, Jie Huang, Yuqi Feng, Jiaxin Zhao, Yalin Zhu, Xiaoming Deng, Xinyu Li, Wangzheqi Zhang, Changli Wang · 2025 · Cellular & Molecular Biology Letters
- Developmental checkpoints guarded by regulated necrosisChristopher P. Dillon, Bart Tummers, Katherine Baran, Douglas R. Green · 2016 · Cellular and Molecular Life Sciences
- Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in miceRyodai Shindo, Takaharu Katagiri, Sachiko Komazawa‐Sakon, Masaki Ohmuraya, Wakami Takeda, Yoshiko Nakagawa, Naomi Nakagata, Tetsushi Sakuma, Takashi Yamamoto, Chiharu Nishiyama et al. · 2020 · Biochemistry and Biophysics Reports
- A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5Yingying Zhang, Kai Huang, Yuxia Zhang, Han Tao, Lang Li, Chenchen Ruan, Ye-hsuan Sun, Wenke Shi, Wei Han, Suqin Wu et al. · 2021 · PLoS Biology
- Primary and Secondary Cone Cell Death Mechanisms in Inherited Retinal Diseases and Potential Treatment OptionsAlicia A. Brunet, Alan R. Harvey, Lívia S. Carvalho · 2022 · International Journal of Molecular Sciences
- Reprogramming of Cell Death Pathways by Bacterial Effectors as a Widespread Virulence StrategyJoseph J. Wanford, Abderrahman Hachani, Charlotte Odendall · 2022 · Infection and Immunity
- Caspase‐8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in miceNathalie Tisch, Carolin Mogler, Ana Stojanovic, Robert Luck, Emilia A. Korhonen, Alexander Ellerkmann, Heike Adler, Mahak Singhal, Géza Schermann, Lena Erkert et al. · 2022 · EMBO Molecular Medicine
- Necroptosis and Neuroinflammation in Retinal DegenerationYan Tao, Yusuke Murakami, Demetrios G. Vavvas, Koh‐Hei Sonoda · 2022 · Frontiers in Neuroscience
- Novel Ser/Thr Protein Phosphatases in Cell Death RegulationHaipeng Sun, Yibin Wang · 2012 · Physiology
- Caspase-8 restricts antiviral CD8 T cell hyperaccumulationYanjun Feng, Lisa P. Daley‐Bauer, Linda Roback, Hongyan Guo, Heather S. Koehler, Marc Potempa, Lewis L. Lanier, Edward S. Mocarski · 2019 · Proceedings of the National Academy of Sciences
- SPATA2: more than a missing linkLisa Schlicher, Prisca Brauns‐Schubert, Florian Schubert, Ulrich Maurer · 2017 · Cell Death and Differentiation
- Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosomeYaping Li, Zhi-ya Zhou, Yan Liang, Yi-Ping You, Hua-yu Ke, Tao Yuan, Haiyan Yang, Rong Xu, Lihui Xu, Dong‐Yun Ouyang et al. · 2024 · Inflammation Research
- An updated view on the functions of caspases in inflammation and immunityMário Songane, Mostafa Khair, Maya Saleh · 2018 · Seminars in Cell and Developmental Biology
- Immunogenic necroptosis in the anti-tumor photodynamic action of BAM-SiPc, a silicon(IV) phthalocyanine-based photosensitizerYing Zhang, Ying-Kit Cheung, Dennis K. P. Ng, Wing‐Ping Fong · 2020 · Cancer Immunology Immunotherapy
- Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelinationSun-Ja Kim, Hsueh Chung Lu, Andrew J. Steelman, Jianrong Li · 2022 · Proceedings of the National Academy of Sciences
- Update of cellular responses to the efferocytosis of necroptosis and pyroptosisChandra Agung Purnama, Anna Meiliana, Melisa Intan Barliana, Keri Lestari · 2023 · Cell Division
- Acute lung injury: a view from the perspective of necroptosisJinyan Dong, Weihong Liu, Wenli Liu, Yuqi Wen, Qingkuo Liu, Hong-Tao Wang, Guo-han Xiang, Yang Liu, Hao Hao · 2024 · Inflammation Research
- Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death networkSabine Pietkiewicz, Roland Eils, Peter H. Krammer, Natalia Giese, Inna N. Lavrik · 2015 · Experimental Cell Research
- IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cellsEdwin C. K. Wan, Peng Li, Rosanne J. Spolski, Jangsuk Oh, Allison B. Andraski, Ning Du, Zu‐Xi Yu, Christopher P. Dillon, Douglas R. Green, Warren J. Leonard · 2015 · Nature Communications
- Cell Death in Liver Disease and Liver SurgeryChristian Stoess, Yeon‐Kyung Choi, Janset Onyuru, Helmut Friess, Hal M. Hoffman, Daniel Hartmann, Ariel E. Feldstein · 2024 · Biomedicines
- Beyond Death: Unmasking the Intricacies of Apoptosis EscapeSercan Ergün, Senanur Aslan, Dilbeste Demir Yeşilyurt, Sümeyye Kayaoğlu, Mevsim Saydam, Yeda Keleş, damla kolcuoğlu, Neslihan Hekim, Sezgin Ozgur Gunes · 2024 · Molecular Diagnosis & Therapy
- Programmed cardiomyocyte death in myocardial infarctionHao Wu, Qi Lan, Yi-Xiang He, Jin-Yi Xue, Hao Liu, Yuan Zou, Ping Liu, Gang Luo, Mingtai Chen, Mengnan Liu · 2025 · APOPTOSIS
- A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosisJohn P. Dowling, Anirudh Nair, Jianke Zhang · 2015 · Frontiers in Cell and Developmental Biology
- The Regulation of Platelet Life SpanEmma C. Josefsson, Mark R. Dowling, Marion Lebois, Benjamin T. Kile · 2012 · Elsevier eBooks
- Cytotoxin 1 from Naja atra Cantor venom induced necroptosis of leukemia cellsYamin Liu, Ming Wei, Yan Wang, Sihong Liu, Yanfen Qiu, Yongxin Xiang, Lili Hu, Lingjie Fan, Xiang Peng, Han Wang et al. · 2019 · Toxicon
- Hierarchical Cell Death Program Disrupts the Intracellular Niche Required for Burkholderia thailandensis PathogenesisDavid E. Place, Shelbi L. Christgen, Shraddha Tuladhar, Peter Vogel, R. K. Subbarao Malireddi, Thirumala‐Devi Kanneganti · 2021 · mBio
- Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damageCharis E. Teh, Simon Preston, Alissa K. Robbins, Michael D. Stutz, James P. Cooney, Michelle P. Clark, Antonia N. Policheni, Cody C. Allison, Liana Mackiewicz, Philip Arandjelovic et al. · 2022 · Science Immunology
- Deubiquitinases in cell death and inflammationKim Newton, Alexander D. Gitlin · 2022 · Biochemical Journal
- Unwinding the modalities of necrosome activation and necroptosis machinery in neurological diseasesRohan V. Gupta, Smita Kumari, Rahul S. Tripathi, Rashmi K. Ambasta, Pravir Kumar · 2023 · Ageing Research Reviews
- Novel, non-conventional pathways of necroptosis in the heart and other organs: Molecular mechanisms, regulation and inter-organelle interplayCsaba G. Horvath, Izabela Jarabicová, Branislav Kura, Barbora Kaločayová, Eva Faurobert, Sean M. Davidson, Adriana Adameová · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Cobalt Chloride Induces Necroptosis in Human Colon Cancer HT-29 CellsHaiyu Wang, Bo Zhang · 2015 · Asian Pacific Journal of Cancer Prevention
- FLIP: A Targetable Mediator of Resistance to Radiation in Non–Small Cell Lung CancerKylie A. McLaughlin, Zsuzsanna Németh, Conor A. Bradley, Luke M. Humphreys, Izabela Stasik, Catherine S. Fenning, Joanna Majkut, Catherine A. Higgins, Nyree Crawford, Caitriona Holohan et al. · 2016 · Molecular Cancer Therapeutics
- Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activationGermana Lentini, Agata Famà, Giuseppe Valerio De Gaetano, Francesco Coppolino, Ahlem Mahjoub Khachroub, Liv Ryan, Egil Lien, Terje Espevik, Concetta Beninati, Giuseppe Teti · 2023 · Cell Reports Medicine
- Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate SignalingYu-Jung Wu, Yung‐Hsuan Wu, Shu-Ting Mo, Huey-Wen Hsiao, You-Wen He, Ming‐Zong Lai · 2015 · The Journal of Immunology
- RIPK1-Associated Inborn Errors of Innate ImmunityJiahui Zhang, Taijie Jin, Ivona A Aksentijevich, Qing Zhou · 2021 · Frontiers in Immunology
- Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis PathwayAh‐Ra Lyu, Tae‐Hwan Kim, Sun-Ae Shin, Eung-Hyub Kim, Yang Yu, Akanksha Gajbhiye, Hyuk-Chan Kwon, A Reum Je, Yang Hoon Huh, Min Jung Park et al. · 2021 · International Journal of Molecular Sciences
- Non-apoptotic function of caspase-8 confers prostate cancer enzalutamide resistance via NF-κB activationJia Xia, Jiahui Zhang, Liangzhe Wang, Hailong Liu, Jie Wang, Junyan Liu, Zhaoqian Liu, Yingjian Zhu, Yingjie Xu, Wen Yang et al. · 2021 · Cell Death and Disease
- Sustained ErbB Activation Causes Demyelination and Hypomyelination by Driving Necroptosis of Mature Oligodendrocytes and Apoptosis of Oligodendrocyte Precursor CellsXu Hu, Guanxiu Xiao, Li He, Xiaojie Niu, Huashun Li, Tianjie Lou, Qianqian Hu, Youguang Yang, Qi Xu, Zhengdong Wei et al. · 2021 · Journal of Neuroscience
- Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repairKristel Martinez Lagunas, Deniz Pinar Savcigil, Matea Zrilić, Carlos Carvajal Fraile, Andrew Craxton, Emily L. Self, Iratxe Uranga-Murillo, Diego de Miguel, Maykel A. Arias, Sebastian Willenborg et al. · 2023 · Science Advances
- Kuguaglycoside C , a constituent of M omordica charantia, induces caspase‐independent cell death of neuroblastoma cellsKeiichi Tabata, Aoi Hamano, Toshihiro Akihisa, Takashi Suzuki · 2012 · Cancer Science
- A systems pharmacology-oriented discovery of a new therapeutic use of the TCM formula Liuweiwuling for liver failureJiabo Wang, Herong Cui, Ruilin Wang, Cong-En Zhang, Ming Niu, Zhaofang Bai, Gen-hua Xu, Peng-yan Li, Wenyan Jiang, Jingjing Han et al. · 2018 · Scientific Reports
- Inhibitory effects of Bombyx mori antimicrobial peptide cecropins on esophageal cancer cellsPing Xu, Dingding Lv, Xihui Wang, Yongsheng Wang, Chengxiang Hou, Kun Gao, Xijie Guo · 2020 · European Journal of Pharmacology
- Enhancing programmed cell death protein 1 axis inhibition in head and neck squamous cell carcinoma: Combination immunotherapyIoannis Athanasios Vathiotis, Jennifer Maria Johnson, Athanassios E. Argiris · 2021 · Cancer Treatment Reviews
- A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathwaysMaryse Dagenais, Jeremy Dupaul-Chicoine, Claudia Champagne, Alexander M. Skeldon, Alexandre Morizot, Maya Saleh · 2015 · Mucosal Immunology
- Multiple ways to die: Non-apoptotic forms of cell deathYoshihide Tsujimoto · 2012 · Acta Oncologica
- In situ vaccination caused by diverse irradiation-driven cell death programsYi‐Jun Wang, Yan Li, Yuxin Yang, Michelle L. Swift, Zhenyu Zhang, Shuhui Wu, Yajie Sun, Kunyu Yang · 2024 · Theranostics
- Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical LabelingJoshua D. Webster, Margaret Solon, Susan Haller, Kim Newton · 2018 · Methods in molecular biology
- PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfectionVincent C. Tam, Rosa Suen, Piper M. Treuting, Aaron M. Armando, Ronald Lucarelli, Norma Gorrochótegui-Escalante, Alan H. Diercks, Oswald Quehenberger, Edward A. Dennis, Alan A. Aderem et al. · 2020 · Proceedings of the National Academy of Sciences
- Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing ReceptorsGaël Galli, Pierre Vacher, Bernhard Ryffel, Patrick Blanco, Patrick Legembre · 2022 · Cells