Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

Israel, Mason A., Yuan, Shauna H., Bardy, Cedric, Reyna, Sol M., Mu, Yangling, Herrera, Cheryl, Hefferan, Michael P., Van Gorp, Sebastiaan +9 more·2012·Nature

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  5. RNA Interference Silencing of Glycogen Synthase Kinase 3β Inhibites Tau Phosphorylation in Mice with Alzheimer Disease
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  8. Neurological diseases at the blood-brain barrier: Stemming new scientific paradigms using patient-derived induced pluripotent cells
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