Engineered CHO cells for production of diverse, homogeneous glycoproteins

Yang·2015·Nature Biotechnology

DOI 10.1038/nbt.3280

Cited by (254)

Items 101–200 of 254

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Joseph R. Brady, Melody C. Tan, Charles A. Whittaker, Noelle Colant, Neil C. Dalvie, Kerry Routenberg Love, John Christopher Love · 2020 · ACS Synthetic Biology
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James Donaldson, Dirk‐Jan Kleinjan, Susan J. Rosser · 2022 · Current Opinion in Biotechnology
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Shengjun Wang, Yongheng Rong, Yaoguang Wang, Decai Kong, Peng George Wang, Min Chen, Yun Kong · 2020 · Microbial Cell Factories
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Mariusz W. Szkudlinski · 2015 · Frontiers in Endocrinology
Impact of Protein Glycosylation on the Design of Viral Vaccines.
K. Schön, B. Lepenies, Guillaume Goyette-Desjardins · 2020 · Advances in Biochemical Engineering/Biotechnology
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Natalie Stewart, Simon Wisnovsky · 2022 · Frontiers in Molecular Biosciences
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Yen‐Pang Hsu, Deeptak Verma, Shu-Wen Sun, Caroline McGregor, Ian K. Mangion, Benjamin F. Mann · 2022 · Communications Biology
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Josh Smith, Stefan Mittermayr, Csaba Váradi, Jonathan Bones · 2017 · The Analyst
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Caroline Benedicte Kjærulff Mathiesen, Michael C. Carlsson, Stéphanie Brand, Svenning Rune Møller, Manja Idorn, Per thor Straten, Anders Elm Pedersen, Sally Dabelsteen, Adnan Halim, Peter Adler Würtzen et al. · 2018 · Journal of Allergy and Clinical Immunology
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Somanath Kallolimath, Thomas Hackl, Raphaela Gahn, Clemens Grünwald‐Gruber, Wilhelm Zich, Benjamin Kogelmann, Anja Lux, Falk Nimmerjahn, Herta Steinkellner · 2020 · Frontiers in Bioengineering and Biotechnology
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Izel Koyuturk, Surbhi Kedia, Anna C. Robotham, Alexandra T. Star, Denis Brochu, Janelle Sauvageau, John F. Kelly, Michel Gilbert, Yves Durocher · 2022 · Biotechnology and Bioengineering
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Joanne L. Allard, Katherine A. Shields, Trent P. Munro, Linda H.L. Lua · 2022 · Chemico-Biological Interactions
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Yuxin Li, Mingzhen Wang, Senlian Hong · 2023 · ChemBioChem
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Cell Line Development
Andreas Castan, Patrick Schulz, Till Wenger, Simon Fischer · 2018 · Elsevier eBooks
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Rin Miyajima, Hitomi Manaka, Tatsuya Honda, Noritaka Hashii, Masato Suzuki, Masahiro Komeno, Koichi Takao, Akiko Ishii‐Watabe, Kazuei Igarashi, Toshihiko Toida et al. · 2023 · Journal of Biotechnology
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