Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

Cited by (690)

Items 601–690 of 690

1. Aptamer-mediated siRNA delivery to target colon cancer stem cells
   Hadi Al Shamaileh · 2016 · Deakin Research Online (Deakin University)
2. Exploring extracellular vesicles for siRNA delivery and Raman-based diagnostics
   Stephan Stremersch · 2016 · Ghent University Academic Bibliography (Ghent University)
3. Nanoparticle-Mediated RNA Interference for Cancer Therapy
   Tomohiro Asai, Leaf Huang, Naoto Oku · 2018 · Elsevier eBooks
4. An Evaluation of Cell Transfection Strategies to Package RNA in Small Extracellular Vesicles
   Jenna L. McCann · 2020 · uO Research (University of Ottawa)
5. Aptamers that bind filovirus GP : a new frontier for detection and neutralization of Ebola and Marburg virus
   Kwaku D. Tawiah · 2020
6. ADME of Biologicals and New Therapeutic Modalities
   R. Foti · 2021 · Elsevier eBooks
7. Preparation and Evaluation of Rationally Designed Polymers for Efficient Endosomal Escape of siRNA
   Chunhui Li, Yuhua Weng, Anjie Dong, Xing‐Jie Liang, Yuanyu Huang · 2021 · Biomaterial engineering
8. Absolute Quantification of Drug Vector Delivery to the Cytosol
   Marco Lucchino, Anne Billet, Siau‐Kun Bai, Estelle Dransart, Justine Hadjerci, Frédéric Schmidt, Christian Wunder, Ludger Johannes · 2021 · Angewandte Chemie
9. Reprogramming of tumor and extracellular vesicular microRNA in relapsed ovarian cancer
   Srujan Kumar Gandham · 2021
10. Sialylation of cell surface glycoconjugates modulates cytosolic galectin-mediated responses upon organelle damage
    I‐Chun Weng, Hung-Lin Chen, Wei‐Han Lin, Fu‐Tong Liu · 2023 · Glycoconjugate Journal
11. A new approach for direct visualization of unlabeled lipid nanoparticles for intracellular pathway analysis
    Filippo Testa, Lucia Salvioni, Marco Giustra, Irene Ostroman, Beatrice Ferrari, Cameron Duncan, Miriam Colombo, Luisa Fiandra, Giovanni Maria Vanacore, Davide Prosperi · 2024 · BIO Web of Conferences
12. Disruption of sphingolipid metabolism promotes tau seeding through endolysosomal membrane rigidification and rupture
    Jessica Tittelmeier, Carl Alexander Sandhof, Nicole Martin, Deike El-Kabarity, Soki-Bradel Ngonza-Nito, Ronald Melki, Carmen I. Nussbaum-Krammer · 2025 · eLife
13. Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency
    Shivani Saxena, Meha Kabra, Amr A. Abdeen, Diana Marcela Tabima, Divya Sinha, Piper A. Rawding, Min Zhu, Ruosen Xie, Tanvi Kulkarni, Giovanni M. Hanstad et al. · 2026 · Nature Communications
14. DNA Nanotubule‐Based Nanodevices with ATP‐Responsive Gating for Direct Cytosolic Delivery of Nucleic Acids and Proteins
    Di Gao, Ziqi Xu, Xiangli Li, Yuhan Zhao, Qianhao Min, Zixuan Chen, Qin Hua Xu, Ye Tian, Junpeng Xu, Junjie Zhu · 2025 · Angewandte Chemie
15. The delivery challenge : synthetic solutions for next-generation gene editing tools
    Oskar Gustafsson · 2025
16. Speed-Up Phase Resolved Fluorescence Lifetime Imaging Microscopy (SUPER-FLIM) for Real-Time Microenvironmental Sensing
    Thomas Kellerer, Lukas Moser, Judith A. Müllerer, Joachim Oskar Rädler, Thomas Hellerer · 2025 · Research Square
17. Lineage of lipid-based endosomal escape in cytosolic delivery to cancer: insight into an unprecedented approach
    Shivani Saraf, Ankita Tiwari, Pritish Kumar Panda, Ankit Jain, Sanjay Jain · 2025 · Journal of Drug Delivery Science and Technology
18. Molecular dynamics-guided design of 2-aminoimidazole derived lipid nanoparticles for efficient muscle transfection
    Zhihao Zhang, Fengyang Han, Hongye Lihe, Linwei Lu, Qiankun Xiong, Xi Kang, Dongsheng Pan, Zimiao Luo, Jiasheng Lu, Weiyue Lu et al. · 2025 · Nano Research
19. Enhancing Safety and Efficacy of Senolytic Therapies with Advanced Controlled Release Strategies
    Lino Ferreira, Vítor Francisco, Andreia Marques, David Sanfeliu-Redondo, Inês Tomé, Susana Carvalho Rosa, João Pitrez, Peio Aristu-Zabalza, Jordi Gracia‐Sancho · 2025 · Research Square
20. Intracellular delivery of full-length antibodies via organ-targeted lipid nanoparticles
    Azmain Alamgir, Militsa Yaneva, Mor Sela, Patricia Mora‐Raimundo, Haim Kadosh, Souvik Ghosal, Anas Odeh, Yuval Richtman, Neta Fibeesh, Yael Leichtmann-Bardoogo et al. · 2026 · Proceedings of the National Academy of Sciences
21. Spatiotemporally Controlled Protein Corona‐Armored DNA Nanomachine for Multitype Biomarker Imaging in Living Cells
    Ziqi Xu, Xueqing Cheng, Xin Guo, Peiling Li, Jiamin Li, Jing Tai Zhao, Zhaoyin Wang · 2025 · Angewandte Chemie
22. Research on Anti-tumor Pharmacodynamics of Multi-functional Magnetic Lipid Polymer with Specific Targeted Transmission of siRNA and its Toxicity Evaluation
    Yaru Liu, Chang Wang, Jie Jin, Jishan Quan, Guangyu Jin · 2025 · Current Pharmaceutical Design
23. Have we finally found the ideal nucleic acid carrier with lipo-xenopeptides?
    Ernst Wagner · 2025 · Expert Opinion on Drug Delivery
24. Bioinspired membrane-fusogenic nanomicelles for synergistic chemotherapy, photodynamic therapy, and gas therapy of breast cancer
    Nan Li, Fengyun Xu, Wei Zhang, Wenke Zhang · 2025 · Materials Today Bio
25. Additional file 1 of Synergistic dual cell therapy for atherosclerosis regression: ROS-responsive Bio-liposomes co-loaded with Geniposide and Emodin
    Li, Zhenxian, Zhu, Haimei, Liu, Hao, Liu, Dayue, Liu, Jianhe, Zhang, Yi, Qin, Zhang, Xu, Yijia, Yuan Peng, Ruan, Lihua et al. · 2024 · Figshare
26. Multi-targeting RNAi approaches for cancer treatment
    Yogitha S. Chareddy, Chad Victor Pecot · 2025 · Expert Opinion on Therapeutic Targets
27. A pH-ultrasensitive membranolytic polymer-assisted delivery system for enhanced siRNA delivery
    Yue Yu, Houbing Zhang, Xianzhu Yang, Jun Wang, Menghua Xiong, Xiaojiao Du · 2026 · Biomaterials Science
28. Nutritional Access Modulates Activity of a Small Molecule Enhancer of Endosomal Escape
    Sten Oskar Vilhelm Wilhelmson-Anden, Hampus Du Rietz, Hampus Hedlund, Johanna M. Johansson, Wahed Zedan, Anders Wittrup · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
29. Towards More Robust Nanobioscience: Launching the NanoBubbles Replication Initiative
    Maha Said, Mustafa Gharib, Raphaël Lévy · 2026 · Angewandte Chemie International Edition
30. Towards More Robust Nanobioscience: Launching the NanoBubbles Replication Initiative
    Maha Said, Mustafa Gharib, Raphaël Lévy · 2026 · Angewandte Chemie
31. Transformer-based multidimensional feature fusion for accurate prediction of lipid nanoparticles transfection efficiency
    Daohong Gong, Xiaowei Xie, Jianxin Tang, Shiliang Li, Hui Li · 2026 · Briefings in Bioinformatics
32. Rapid growth and thematic shifts in mRNA therapeutics research catalyzed by the COVID-19 pandemic
    Prabakaran Annadurai · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
33. LNP-mRNA therapeutics: Mechanism of action
    Pramod Patil, Umesh D. Shivhare, Namdeo Jadhav · 2026 · Elsevier eBooks
34. Endoplasmic reticulum stress induced autophagy alters cellular processing of cationic lipid delivered siRNAs
    R. Chauncey Splichal, Christina Chan, S. Patrick Walton · 2026 · Drug Delivery and Translational Research
35. RNA interference via lipid nanoparticles: An innovative perspective for the treatment of non-small cell lung cancer
    Gabriela Thomazotti Estevez Claro Roberto, Jéssica Fagionato Masiero, Marco Antônio Stephano, Nádia Araci Bou‐Chacra · 2026 · Journal of Drug Delivery Science and Technology
36. Peptide nanomicelles for NIR light-dependent siRNA delivery
    Taufik Fatwa Nur Hakim, Mizuki Kitamatsu, Shoumu Fujimoto, Kazunori Watanabe, Takashi Ohtsuki · 2026 · Results in Chemistry
37. Quantification of membrane translocation and endosomal escape : a chemical biology approach
    Marco Lucchino · 2019
38. A synthetic B-subunit of Shiga toxin with enhanced cytosolic delivery efficiency for innovative anticancer immunotherapies
    Anne Billet · 2021 · theses.fr (ABES)
39. Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of α-synuclein
    Yuteng Zeng, Ziyan Lv, Jiayu Liang, Yetao Wu, Liang Han · 2026 · Acta Biomaterialia
40. Considerations on antibody-based active targeting strategies for lipid nanoparticle delivery systems
    Janell Ko, Jordan Tom, Miffy H. Y. Cheng · 2026 · AAPS Open
41. Caractérisation de la réponse lymphocytaire B mémoire contre le SARS-CoV-2 après infection ou vaccination
    Aurélien Sokal · 2022 · theses.fr (ABES)
42. DNA Nanostructures for siRNA Delivery
    Bharath Raj Madhanagopal, Sarah Youssef, Arun Richard Chandrasekaran · 2026 · Bioconjugate Chemistry
43. Modern Materials for Non-Viral Delivery Systems in Gene Therapy
    A.V. Radnaeva, Ekaterina A. Slobodkina, V. A. Tkachuk, P. I. Makarevich · 2026 · Biomedical Chemistry Research and Methods
44. Reprogramming tumor-associated macrophages using siRNA-loaded lipid nanoparticles
    Sezen Gul · 2025 · theses.fr (ABES)
45. Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue
    Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang · 2026 · Advanced Science
46. Rapid and reliable quantification of cytosolic mRNA escape (RNASCAPE)
    Frank Schulz, Emily Winther Sørensen, Steen W.B. Bender, Artù Breuer, Georgios Kyriakakis, Jacob Kæstel‐Hansen, Georgios Bolis, Athanasios Oikonomou, Konstantinos Tsolakidis, Stefanos Arampatzis et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
47. Osmotic Pressure–Driven Lipid Nanoparticles Enable Potent Cytosolic Delivery of Nucleic Acids
    Thuy Giang Nguyen Cao, Hoang Quan Truong, Yanghao Li, Urmila Kafle, Fanfei Meng · 2026 · Small
48. A biomimetic nanotherapeutic hydrogel orchestrates multi-mechanism therapy for ischemic skin flaps
    Sheng Cheng, Zhanqiu Dai, Shanshan Xi, Jiayi Zhao, Jian Ding, Zijie Wang, Haoze Yu, Zinuo Wang, Yuanna Sun, Ismail Muhammad et al. · 2026 · Biomaterials
49. Research Advances and Challenges in Antibody-Conjugated Nucleic Acid Drugs
    一品 孙 · 2026 · Pharmacy Information
50. Enhanced Intramuscular mRNA Activity of Peptide–Lipid Nanoparticles with Hydrophobized Head Groups
    Eric Weidinger, Tobias Burghardt, Lennart Obeser, Janin Germer, Jana Pöhmerer, Mina Yazdi, Miriam Höhn, Daniel Merk, Ernst Wagner · 2026 · Bioconjugate Chemistry
51. Molecular Engineering of the Nano‐Bio Interface for Programmable and Precision Protein Delivery
    Ma Tc, Rui Yao, Qingyan Zhang, Ming Wang · 2026 · Advanced Materials
52. Nanocarriers for nucleic acid delivery
    Rajiv Yadav · 2026 · Elsevier eBooks
53. Identification of a cell subpopulation with different response to lipid nanoparticles and effect of protein corona on uptake and transfection
    Heba A Fayyaz, Rixt I. Noordhof, Mia Fitriana, Anna Laura Salvati · 2026 · Materials Today Bio
54. Engineered Lipid Nanoparticles with Promoted Endosomal Escape and R283S-Mediated Stimulator of Interferon Genes (STING) Activation for Pancreatic Cancer Immunotherapy
    Sizhen Wang, Qiwei Tai, Kehui Wang, Jianyu Zheng, Beibei Guo, Feng Hua Yang, C Wang · 2026 · Pharmaceutics
55. Recent progress in nanoparticulate lipid-based co-delivery systems containing gene-based cargoes for the treatment of oncological and non-oncological diseases
    Reza Hosseinpour-Moghadam, Sima Sadrai, Tayebeh Toliyat · 2026 · Pharmaceutical Development and Technology
56. Nanoscale biointerfaces in inter-organelle communication: membrane contact sites, organelle trafficking, and cell fate control
    Mohamed R Abdel-Hamed, Sameh Saber, Elsayed A. Elmorsy, Basem Hassan Elesawy, Maha M. Amer, Abdel-Moneim Hafez Abdel-Moneim, Alaa El Din Firgany, Enas A. Mohamed, Huda Eltayeb, Ageeb M. Hassan et al. · 2026 · Frontiers in Cell and Developmental Biology
57. Polymeric Delivery Vehicles for Nucleic Acid Vaccines: Design Strategies and Biological Barriers
    Pijun Su, Huilin Yuan, Kangxin Zhang, Nuo Dong, Huapan Fang, Huayu Tian · 2026 · ACS Applied Materials & Interfaces
58. Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
    Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee · 2026 · Advanced Functional Materials
59. Initial Molecular Detection of Membrane Damage in Post-Golgi Compartments
    Yoko Shiba, Nana Saito · 2026 · Cells
60. In vivo imaging of lipid nanoparticle messenger RNA therapeutics: Current advances and emerging opportunities
    Natacha Jugniot · 2026 · European Journal of Medicinal Chemistry
61. Stimulus-Responsive Polymeric Carriers for Gene Delivery: Balancing Endosomal Escape with Nucleic Acid Release
    Kenneth Hulugalla, Alexander W. Fortenberry, Dilusha J. de Silva, Thomas Werfel · 2026 · Pharmaceutical Research
62. Lipid Nanoparticles for Gene Therapy: Unresolved Challenges in Manufacturing, Transdermal Delivery, Machine Learning, Endosomal Escape, and the Protein Corona
    Ognjen Milić, Sanela M. Savic, Melanija Zurković, Boban Stanojević, Snezana D. Savic · 2026 · Pharmaceutics
63. SNAI1 ablation alters integrin-mediated adhesion and endocytic fate
    Chrysoula Tsirigoti, Mohamad Moustafa Ali, Anita Morén, Staffan Johansson, Michael J. Munson, Carl‐Henrik Heldin, Aristidis Moustakas, Dorival Mendes Rodrigues‐Junior · 2026 · Cell Death and Disease
64. Bioactive lipid-derived nanoparticles for RNA delivery
    Kaiqi Long, Jeffrey Yuan, Yang Zhang, Yongjiang Li, Minling Zhong, Weiping Wang, Jinjun Shi · 2026 · Materials Today
65. A Comprehensive Review of COVID-19 Vaccines: Development, Efficacy, Safety, and Immunity
    Hashimul Ehsan · 2026 · Journal of Immunology and Clinical Microbiology
66. Layer by Layer Engineered Lipid-Based Nanocarriers for Therapeutic Delivery and Next-Generation Design
    Eunseok Jang, Gaeun Lee, Yoseph Seo, Hyunjun Park, Suk Min Yun, Sang Deuk Lee, Giwon Lee, Chulhwan Park, Taek Lee · 2026 · Pharmaceutics
67. Delivering Degradation: Nanomedicine and Programmable Proximity Platforms for Targeted Protein Degradation
    Adnan Amin, Touseef Nawaz, Oberdan Oliveira Ferreira, Mozaniel Santana de Oliveira · 2026 · Pharmaceutics
68. Extracellular Vesicle–Lipid Hybrid Systems for RNA Delivery in Cancer: Structural Classification, Functional Delivery, and Translational Challenges
    Lu Lu, Yige Qiu, Jiayu Wu, Wei Dou, Jing Yang, Bo Zhang · 2026 · Pharmaceutics
69. Strand-Resolved Mapping of siRNA Trafficking in Cells by Nanoscale Secondary Ion Mass Spectrometry
    Kai Chen, Mehran Nikan, Xu Li, Sitao Hu, Michael T. Migawa, JinYu Guo, Paul R. Guagliardo, K. Swaminathan Iyer, C. Frank Bennett, Punit P. Seth et al. · 2026 · ACS Nano
70. Research Advances on Organelle-Targeted Drug Delivery Systems for the Treatment of Brain Tumors and Central Nervous System Inflammation
    Manru Zhang, Bohan Chen, Tiezheng Li, Xiaolong Li, Jingxian Sun, Qiushuo Li, Mingji Jin, Zhonggao Gao, Liqing Chen, Wei Huang · 2026 · Pharmaceutics
71. Beyond efficiency: the AI-driven shift toward safer lipid nanoparticles for gene delivery
    Hai-Xin Xie, Jia-Qi Liu, Min Zhao, Tian‐Jiao Zhou, Lei Xing, Xian Wu Cheng, Zhiyi Tian, Yi Wang, Hu‐Lin Jiang · 2026 · Journal of Controlled Release
72. Autolysosomal degradation-inhibitory nanoparticles for enhanced mRNA escape and cytokine therapy
    Ti-Qiang Zhou, Weilun Sun, Haiyin Yang, Gang Zhang, Abid Naeem, Yuhua Weng, Mengliang Zhu, Zhen-Zhen Wei, Yuanyu Huang, Xing‐Jie Liang · 2026 · Cell Biomaterials
73. Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides Enhances mRNA Efficacy via Reduced Endosomal Retention
    Yuxin He, Lin Wang, Abigael P. Williams, Trisha I. Valerio, Yuanhong Sun, James Bowman, Samantha D. Ricketts, Savannah Hammond, Aidan Sison, Jezan Alexandre et al. · 2026 · ACS Nano
74. Beyond Uptake in Cancer Lipid Nanomedicines: Linking Tumour Access, Intracellular Fate, and Molecular Action
    Syed Alhafiz Syed Hashim · 2026 · Pharmaceutics
75. The Nanoparticle Delivery Gap in Immune Cell Engineering: From Uptake to Endosomal Escape
    Alireza Gharatape, Alireza Alikhanian, Javad Verdi, Yahya Essop Choonara, Reza Faridi Majidi · 2026 · International Journal of Nanomedicine
76. An Integrated DNA Origami-Based RNA Degrader for Targeted Degradation of Oncogenic Mutant KRAS mRNA
    Ying-Fu Li, Qing Huang, Pin-Ru Chen, Hua-Dong Li, Pei‐Qiang Ma, Bang‐Ce Ye, Bin‐Cheng Yin · 2026 · ACS Pharmacology & Translational Science
77. Microfluidic channel engineering for mRNA–LNPs: a systematic review of mixing strategies, nanostructures, and biological performance
    Hyejoong Jeong, Cheol Hui Park, Bookun Kim, Junsang Doh, 구희범 · 2026 · Lab on a Chip
78. Delivery architectures for oligonucleotide therapeutics in genetic and rare diseases: GalNAc-based hepatocyte targeting and extrahepatic translation
    Chan Hyeok Lee, Hyunjun Moon, Kang Hyeok Lee, Jin Hee Na, Jeong Uk Choi, Jin Woo Choi, Sangmin Lee · 2026 · Journal of Controlled Release
79. RNA therapeutics in rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis: a compartment-aware translational framework
    Yusif Afandizada, Hikmet Memmedov, Mushfig Orujov, Shahla Eyvazova, Shirkhan Amikishiyev · 2026 · Frontiers in Immunology
80. Mapping programmable mRNA research relevant to cancer-associated immune escape: a dual-database bibliometric and topic modeling analysis
    Xiao-Jie Zhou, Jun-chi Zhu, Jian Dong, Shi-Ying Yan, Zhang Si-yin, Jun-Ting Dong, Bai-Qi Zhang, Hong-Ru Che, Chen-hao Zhang, Rui Zhang et al. · 2026 · Frontiers in Oncology
81. Self-Monitoring Theranostic Nanomaterials for Biomedical Imaging and Cancer Therapy: Real-Time Visualization of Biodistribution, Payload Release, and Therapeutic Response
    Chanju Choi, Dongseong Seo, Jonghyun Park, Dongmin Yu, Sihyun Song, Sohyeon Yu, Jeongmin Shin, Simseok A. Yuk, Daekyung Sung, Hyungjun Kim · 2026 · Nanomaterials
82. Ionizable Lipid Nanoparticles as a siRNA Delivery Carrier: A Review
    Vishal Prajapat, Gaurav Sharma, Narender K. Dhania, Auhin Kumar Maparu · 2026 · ACS Applied Nano Materials
83. Beyond Nanosizing: Mechanism-Guided Design and Rational Selection of Polymeric and Lipid Nanocarriers for Translatable Drug Delivery
    Bishal Singh, Abhisekh Sah, Rajesh Gautam, Gaurav Thakur, Deepak Kumar, Jigyasa Jayaswal, Shivam Kumar · 2026 · DARU Journal of Pharmaceutical Sciences
84. Strategies for controllable siRNA delivery in gene silencing and cancer therapy
    Nana Feng, Yang Liu · 2026 · Science China Materials
85. Precision engineering of nanocarriers for transport across complex biological barriers
    Rumi Acharya, Elena Komedchikova, Yonghyun Choi, Jihyuk Yang, Jiwon Kim, Jaewoo Son, Jaehee Jang, Heeyoung Lee, Tetsuya Kadonosono, 최종훈 · 2026 · International Journal of Pharmaceutics X
86. Advanced Nucleic Acid Architectures: Classification, Assembly Mechanisms, and Biomedical Applications
    Yan Liu, Caiyun Zhao, Chengke Zhao, Siying Li, Chang Xu, Han Wu, Xiaojing Pei, Hong Meng · 2026 · Pharmaceutics
87. Raman-Trackable Heterojunction Nano-Objects for Pre-Delivery Mapping of Intracellular Trafficking Bottlenecks: A Critical Review
    Dilpreet Singh · 2026 · Nano Trends
88. siRNA therapeutics: from hepatic delivery to extrahepatic targeting
    Nan Wang, Lingxi Meng, Jia-Xin Shi, Matthias Bartneck · 2026 · Expert Opinion on Drug Delivery
89. Modulating the osteoimmune microenvironment: biomaterial strategies for bone regeneration and implant integration
    Xiangming Li, Bingqi Zhou, Ruochen Yang, Penghui Li · 2026 · Human Cell
90. Plant-Derived Exosome-Like Nanovesicles from Mechanistic Understanding Toward Clinical Translation in Cancer Therapy.”
    Akanksha Patil, Vijay Mahadev Kumbar, Priya Patil, Vaishnavi Pawashe, Sucheta Banerjee Kurundkar, Malleswara Rao Peram, Ramesh Pranjapee · 2026 · Pharmacological Research - Natural Products