The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Wide field-of-view, multi-region, two-photon imaging of neuronal activity in the mammalian brain
Open accessAbstract
Two-photon calcium imaging provides an optical readout of neuronal activity in populations of neurons with subcellular resolution. However, conventional two-photon imaging systems are limited in their field of view to ∼1 mm2, precluding the visualization of multiple cortical areas simultaneously. Here, we demonstrate a two-photon microscope with an expanded field of view (>9.5 mm2) for rapidly reconfigurable simultaneous scanning of widely separated populations of neurons. We custom designed and assembled an optimized scan engine, objective, and two independently positionable, temporally multiplexed excitation pathways. We used this new microscope to measure activity correlations between two cortical visual areas in mice during visual processing.
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Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex
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Genetic Dissection of Neural Circuits: A Decade of Progress
Luo, L., Callaway, E. M., & Svoboda, K. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.040 · Cited by 448
In vivo imaging of neural activity
Yang, W., & Yuste, R. (2017) · Nature Methods · doi:10.1038/nmeth.4230 · Cited by 406
dal Maschio, M., Donovan, J. C., Helmbrecht, T. O., & Baier, H. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.034 · Cited by 169
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Metadata
- Authors
- Stirman, J. N., Smith, I. T., Kudenov, M. W., & Smith, S. L.
- Venue
- Nature Biotechnology
- Published
- 2016-06-27
- Volume
- 34
- Issue
- 8
- Pages
- 857-862
- ISSN
- 0733-222X (ISSN-L)
- 1087-0156
- 1546-1696
- OpenAlex
- W2472683490
- Cited by
- 331
- References
- 28
- FWCI
- 22.09
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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