The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Lysosome positioning coordinates mTORC1 activity and autophagy
Abstract
Under nutrient-rich conditions, the nutrient-sensitive kinase mTOR (mammalian target of rapamycin) is recruited to the surface of lysosomes where it becomes activated and can promote cell growth and inhibit autophagy. In contrast, mTOR is inhibited in nutrient-poor conditions, leading to the induction of autophagy. The intracellular positioning of lysosomes in response to nutrient availability is now shown to orchestrate mTOR activation and regulate autophagy.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Intracellular localization of lysosomes regulates their ability to interact and fuse with vesicles such as autophagosomes or endosomes.
“Notably, intracellular localization of lysosomes regulates their ability to interact and fuse with vesicles such as autophagosomes or endosomes31, 32, 47, 48.”
From Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation (2020) · cites this paper as [48]
Citations
Cites
Sancak, Y., Bar-Peled, L., Zoncu, R., Markhard, A. L., Nada, S., & Sabatini, D. M. (2010) · Cell · doi:10.1016/j.cell.2010.02.024 · Cited by 2,464
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., Iemura, S.-I., Natsume, T., Takehana, K., Yamada, N., et al. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1248 · Cited by 2,076
Termination of autophagy and reformation of lysosomes regulated by mTOR
Yu, L., McPhee, C. K., Zheng, L., Mardones, G. A., Rong, Y., Peng, J., Mi, N., Zhao, Y., Liu, Z., Wan, F., et al. (2010) · Nature · doi:10.1038/nature09076 · Cited by 1,544
Plasma membrane contributes to the formation of pre-autophagosomal structures
Ravikumar, B., Moreau, K., Jahreiss, L., Puri, C., & Rubinsztein, D. C. (2010) · Nature Cell Biology · doi:10.1038/ncb2078 · Cited by 902
Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH
Heuser, J. (1989) · The Journal of cell biology · doi:10.1083/jcb.108.3.855 · Cited by 390
Flagged first, then by citations
Research works printed but not linked: 10
- Wullschleger, S., Loewith, R. & Hall, M. N. Cell 124, 471–484 (2006). · DOI · Paper page
- Meijer, A. J. & Codogno, P. Crit. Rev. Clin. Lab. Sci. 46, 210–240 (2009). · DOI
- Korolchuk, V. I. et al. Nat. Cell Biol. 13, 453–460 (2011). · DOI · Paper page
- Matsushita, M., Tanaka, S., Nakamura, N., Inoue, H. & Kanazawa, H. Traffic 5, 140–151 (2004). · DOI
- Santama, N. et al. EMBO J. 17, 5855–5867 (1998). · DOI
- Hofmann, I. & Munro, S. J. Cell Sci. 119, 1494–1503 (2006). · DOI
- Wellen, K. E. & Thompson, C. B. Mol. Cell 40, 323–332 (2010). · DOI · Paper page
- Nakatogawa, H., Suzuki, K., Kamada, Y. & Ohsumi, Y. Nat. Rev. Mol. Cell Biol. 10, 458–467 (2009). · DOI
- Bodemann, B. O. et al. Cell 144, 253–267 (2011). · DOI
- Beau, I. & Codogno, P. Mol. Cell 39, 485–486 (2010). · DOI
Cited by
Sorted by citations
Autophagy and microtubules - new story, old players
Mackeh, R., Perdiz, D., Lorin, S., Codogno, P., & Poüs, C. (2013) · Journal of Cell Science · doi:10.1242/jcs.115626 · Cited by 212
Self-citationInhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion
Choi, Y. J., Park, Y. J., Park, J. Y., Jeong, H. O., Kim, D. H., Ha, Y. M., Kim, J. M., Song, Y. M., Heo, H.-S., Yu, B. P., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043418 · Cited by 192
Qin, Y., Ting, F., Kim, M. J., Strelnikov, J., Harmon, J., Gao, F., Dose, A., Teng, B.-B., Alipour, M. A., Yao, Z., et al. (2020) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.120.314033 · Cited by 18
Metadata
- Authors
- Poüs, C., & Codogno, P.
- Venue
- Nature Cell Biology
- Published
- 2011-04
- Volume
- 13
- Issue
- 4
- Pages
- 342-344
- ISSN
- 1465-7392
- 1476-4679
- Cited by
- 61
- References
- 5
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
