The Patched dependence receptor triggers apoptosis through a DRAL–caspase-9 complex
Mille, Frédéric, Thibert, Chantal, Fombonne, Joanna, Rama, Nicolas, Guix, Catherine, Hayashi, Hideki, Corset, Véronique, Reed, John C., Mehlen, Patrick·2009·Nature Cell Biology
DOI 10.1038/ncb1880
Cited by (155)
Items 101–155 of 155
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- Hedgehog Signaling Plays a Dual Role in Pancreatic CarcinogenesisTara L. Hogenson, Rachel Olson, Martín E. Fernández-Zapico · 2018 · Springer eBooks
- Pathophysiology of Cancer Cell DeathLorenzo Galluzzi, Oliver Kepp, Guido Kroemer · 2014 · Elsevier eBooks
- Non-apoptotic caspase activation sustains ovarian somatic stem cell functions by modulating Hedgehog-signalling and autophagyAlessia Galasso, Daria Iakovleva, Luis Alberto Baena-López · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Probing the biological efficacy and mechanistic pathways of natural compounds in breast cancer therapy via the Hedgehog signaling pathwayYining Chen, Wen‐Feng Zhang, Qi Sun, Xue Wang, Qihang Shang, Jingyang Liu, Yubao Zhang, Ruijuan Liu, Changgang Sun · 2024 · Journal of Pharmaceutical Analysis
- Apoptosis and CancerMing Tan, Heng Kean Tan, Tengku Sifzizul Tengku Muhammad · 2014 · Springer eBooks
- Apoptosis-reactivating agents for targeted anticancer therapyAlex A. Philchenkov · 2012 · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry
- Targeting the Hedgehog and PI3K/AKT/mTOR signaling pathways in rhabdomyosarcomaNatalie Geyer · 2018 · eDiss (Georg-August-Universität Göttingen)
- Integrated protein-protein interaction and RNA interference screens reveal novel restriction and dependency factors for a tick-borne flavivirus in its human hostMarion Sourisseau, Yves Unterfinger, Manon Lemasson, Maxime Chazal, Ségolène Gracias, Grégory Caignard, François Piumi, Axel Grot, Sara Moutailler, Damien Vitour et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Hedgehog signaling pathway is an influential factor on vascular biology: a reviewMi Ai, Xiao Li, Yilin Yu, Laidi Wu, Ollie Yiru Yu, Yingguang Cao, Jianmiao Liu, Ke Song · 2025 · Journal of Physiology and Biochemistry
- Partial truncation of the C-terminal domain of PTCH1 in cancer promotes tumourigenesis by non-canonical activation of a GLI-PI3K loopBegoña Caballero-Ruiz, Rosa Bordone, Sonia Coni, Danai S. Gkotsi, Eva Gonzalez, Gianluca Canettieri, Natalia A. Riobo‐Del Galdo · 2026 · Oncogene
- A Prickly Subject: Apoptotic Regulation by Hedgehog MorphogensMark Ditzel · 2011 · The Open Cell Signaling Journal
- Apoptosis and CancerMing Tan, Shahrul Bariyah Sahul Hamid, Muhammad Asyraf Abduraman, Heng Kean Tan · 2020 · Springer eBooks
- Hedgehog Signaling Plays a Dual Role in Pancreatic CarcinogenesisTara L. Hogenson, Rachel Olson, Martín E. Fernández-Zapico · 2016 · Springer eBooks
- Hedgehog Signaling in Development and DiseaseDagan Jenkins · 2015 · Elsevier eBooks
- Mitochondria in Cell Death RegulationIlio Vitale, Gwenola Manic, Guido Kroemer, Lorenzo Galluzzi · 2015 · Elsevier eBooks
- Role of the Hedgehog receptor Patched1 in the development and function of T lymphocytesKai D. Michel · 2013 · eDiss (Georg-August-Universität Göttingen)
- Protein Kinases and Caspases: Bidirectional Interactions in ApoptosisStephanie A. Zukowski, David W. Litchfield · 2015 · Wiley eBooks
- MOLECULAR STUDIES ON LIM-DOMAIN PROTEIN CRP1Päivi P. Järvinen · 2011 · Työväentutkimus Vuosikirja
- Differential Regulation of c-FLIP Isoforms Through Post-translational ModificationsAura Kaunisto · 2009 · UTUPub (University of Turku)
- Necrobiology of Liver Cancer: Apoptosis and Related Forms of Cell DeathArthur Zimmermann · 2016 · Springer eBooks
- The Role of Morphogens in B Cell DevelopmentCynthia Eloho Umukoro · 2016 · UEL Research Repository (University of East London)
- The molecular intersection between axon-specific pruning and neuronal apoptosisCorey L. Cusack · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
- Hedgehog Signaling is a Mediator of the Gastric Immune Response to Helicobacter pylori InfectionMichael A. Schumacher · 2014 · OhioLink ETD Center (Ohio Library and Information Network)
- Characterizing the Structure and Function of the Cytoplasmic Domains of Ptch1Jennifer Pui-Yee Lee · 2016 · TSpace (University of Toronto)
- Necrobiology of Liver Cancer: Apoptosis and Related Forms of Cell DeathArthur Zimmermann · 2016 · Springer eBooks
- Hedgehog Signalling in Development and DiseaseDagan Jenkins · 2022 · Elsevier eBooks
- The neurotrophin receptor TrkC, a new dependence receptor involved in the control of neuroblastoma tumorigenesisJimena Bouzas-Rodríguez · 2010 · theses.fr (ABES)
- Rôle de la voie hedgehog dans la fibrose pulmonaire idiopathiqueElika Farrokhi Moshai · 2013 · theses.fr (ABES)
- Virus de l'hépatite C, Nétrine-1 et réponse aux protéines mal repliées en contexte hépatiqueThomas Lahlali · 2014 · theses.fr (ABES)
- Les effets des lipides exosomaux sur les cellules tumorales pancréatiques humaines : entre apoptose et survieSadia Beloribi‐Djefaflia · 2014 · theses.fr (ABES)
- In vitro anticancer activity of new gold (III) porphyrin complexes in colon cancer cellsFatima Dandash · 2017 · theses.fr (ABES)
- Étude du rôle de la protéine de liaison aux ARN messagers Smaug dans la voie Hedgehog chez la drosophileCamilla Argüelles · 2017 · theses.fr (ABES)
- Rôle de la voie de signalisation Sonic Hedgehog dans les cellules Glast positives du cerveau de souris adulteLinda Tirou · 2020 · theses.fr (ABES)
- Implication des récepteurs à dépendance dans le processus tumoral : mécanismes et exploitation en thérapie anti-cancéreuseCéline Delloye‐Bourgeois · 2011 · theses.fr (ABES)
- La signalisation Hedgehog dans le maintien de la barrière hémato-encéphalique et la physiopathologie des troubles neurodégénératifsPierre-Louis Hollier · 2020 · theses.fr (ABES)
- Regulation of Netrin-1 by p53 isoformsYan Sun · 2020 · theses.fr (ABES)
- Mécanismes moléculaires et cellulaires impliqués dans la production de la myéline induite par les voies de signalisation Hedgehog et des androgènes dans le système nerveux centralAbdelmoumen Kassoussi · 2021 · theses.fr (ABES)
- A new role for Barhl1 in a cerebellar germinative zone as inhibitor of T-cell factors transcriptional activityJohnny Bou‐Rouphael · 2023 · theses.fr (ABES)
- Deciphering the mechanisms of nerve/tumor Interaction : role of the axon guidance signaling Netrin-1/DCCHiba Haidar · 2024 · theses.fr (ABES)
- Caractérisation du récepteur Smoothened en tant que régulateur majeur des états fonctionnels des cellules microglialesAdil El Mesaoudi · 2024 · theses.fr (ABES)
- Modulating primary cilia and cilia-dependent Shh signaling increases retinal ganglion cell survival by repressing astrocyte reactivity after optic nerve injuryQuanyu He, Xuehan Liu, Qi Zhang, Yuxuan Qiu, Jiahui Tang, Bing Zhang, Siting Wu, Canying Liu, Liyan Liu, Yehong Zhuo et al. · 2026 · Neurobiology of Disease
- BindingDB Entry 50006997: Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies.BindingDB · 2021 · UC San Diego
- Mechanisms of microenvironmental conditioning in non-Hodgkin’s lymphomaLihui Zhuang · 2012 · ERA