p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

Fujita, Kaori, Mondal, Abdul M., Horikawa, Izumi, Nguyen, Giang H., Kumamoto, Kensuke, Sohn, Jane J., Bowman, Elise D., Mathe, Ewy A. +7 more·2009·Nature Cell Biology

Cited by (336)

Items 101–200 of 336

  1. High-resolution functional annotation of human transcriptome: predicting isoform functions by a novel multiple instance-based label propagation method
    Wenyuan Li, Shuli Kang, Chun-Chi Liu, Shihua Zhang, Yi Shi, Yan Liu, Xianghong Jasmine Zhou · 2013 · Nucleic Acids Research
  2. Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity
    Virginie Marcel, Isabelle Petit, Fiona Murray-Zmijewski, Théo Goullet de Rugy, Kenneth Fernandes, Valerie Meuray, Alexandra Diot, David Philip Lane, Daniel Aberdam, Jean‐Christophe Bourdon · 2011 · Cell Death and Differentiation
  3. Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence
    Hind Hafsi, Pierre L. Hainaut · 2011 · Antioxidants and Redox Signaling
  4. Effects of Δ40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53
    Hind Hafsi, Daniela Santos‐Silva, Stéphanie Courtois-Cox, Pierre L. Hainaut · 2013 · BMC Cancer
  5. Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide
    Ewy A. Mathé, Giang Huong Nguyen, Naotake Funamizu, Peijun He, Matthew M. Moake, Carlo Maria Croce, S. Perwez Hussain · 2011 · International Journal of Cancer
  6. Senescence: an antiviral defense that is tumor suppressive?
    Roger R. Reddel · 2009 · Carcinogenesis
  7. Adaptive homeostasis and the p53 isoform network
    Sunali Y. Mehta, Hamish G. Campbell, Catherine J. Drummond, Kunyu Li, Kaisha Murray, Tania L. Slatter, Jean‐Christophe Bourdon, Antony W. Braithwaite · 2021 · EMBO Reports
  8. p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation
    Min-Ho Yoon, So‐mi Kang, Su Jin Lee, Tae‐Gyun Woo, Ah-Young Oh, So‐Young Park, Nam‐Chul Ha, Bum-Joon Park · 2019 · Cell Death and Disease
  9. MicroRNAs as a novel cellular senescence regulator
    Fengjiao Liu, Tie Wen, Ling Liu · 2011 · Ageing Research Reviews
  10. Ratio disruption of the Δ133p53 and TAp53 isoform equilibrium correlates with poor clinical outcome in intrahepatic cholangiocarcinoma
    NICHAPAVEE NUTTHASIRIKUL, Temduang Limpaiboon, Chanvit Leelayuwat, Siriporn Patrakitkomjorn, Patcharee Jearanaikoon · 2013 · International Journal of Oncology
  11. p53 Basic C Terminus Regulates p53 Functions through DNA Binding Modulation of Subset of Target Genes
    Pierre-Jacques Hamard, Dana J. Lukin, James J. Manfredi · 2012 · Journal of Biological Chemistry
  12. Caffeine induces tumor cytotoxicity via the regulation of alternative splicing in subsets of cancer-associated genes
    Guan‐Yu Lu, Shih‐Ming Huang, Shuting Liu, Pei‐Yao Liu, Wei‐Yuan Chou, Wei‐Shiang Lin · 2013 · The International Journal of Biochemistry & Cell Biology
  13. The interplay between Epstein-Bar virus (EBV) with the p53 and its homologs during EBV associated malignancies
    Koustav Chatterjee, Piyanki Das, Nabanita Roy Chattopadhyay, Sudipa Mal, Tathagata Choudhuri · 2019 · Heliyon
  14. VEGF receptor‐1 modulates amyloid β 1–42 oligomer‐induced senescence in brain endothelial cells
    Ramcharan Singh Angom, Ying Wang, Enfeng Wang, Krishnendu Pal, Santanu Bhattacharya, Jens O. Watzlawik, Terrone L. Rosenberry, Pritam Das, Debabrata Mukhopadhyay · 2018 · The FASEB Journal
  15. The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer
    Marina Kazantseva, Sunali Y. Mehta, Ramona A. Eiholzer, Grégory Gimenez, Sara Bowie, Hamish G. Campbell, Ashley L. Reily-Bell, Imogen M. Roth, Sankalita Ray, Catherine J. Drummond et al. · 2019 · Cell Death and Disease
  16. Matrine-induced autophagy regulated by p53 through AMP-activated protein kinase in human hepatoma cells
    SHAN-BU XIE, Xingxing He, Shukun Yao · 2015 · International Journal of Oncology
  17. The RNA world of human ageing
    Juan Carlos Gómez-Verján, Edgar Ricardo Vázquez-Martínez, Nadia Alejandra Rivero-Segura, Raúl Hernán Medina-Campos · 2018 · Human Genetics
  18. Non-canonical functions of spliceosome components in cancer progression
    Olga M. Ivanova, Ksenia S. Anufrieva, Anastasia N. Kazakova, Irina K. Malyants, Polina V. Shnaider, Maria M. Lukina, Victoria О. Shender · 2023 · Cell Death and Disease
  19. Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
    Ricardo Iván Martínez‐Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira de Freitas, Themistoklis Vasilopoulos, Mark Simpson, Grégory R G Doré, Pierre‐François Roux, Mark A. Galan, Ravi J. Chokshi, Oliver Bischof et al. · 2023 · Cell Genomics
  20. Conformational stability and dynamics of the cancer‐associated isoform Δ133p53β are modulated by p53 peptides and p53‐specific DNA
    Jiangtao Lei, Ruxi Qi, Yegen Tang, Wenning Wang, Guanghong Wei, Ruth Nussinov, Buyong Ma · 2018 · The FASEB Journal
  21. Canonical and non-canonical functions of p53 isoforms: potentiating the complexity of tumor development and therapy resistance
    Yitian Guo, Hang Wu, Lisa Wiesmüller, Ming Chen · 2024 · Cell Death and Disease
  22. Expression of Senescence-Associated microRNAs and Target Genes in Cellular Aging and Modulation by Tocotrienol-Rich Fraction
    Sharon Gwee Sian Khee, Yasmin Anum Mohd Yusof, Suzana Makpol · 2014 · Oxidative Medicine and Cellular Longevity
  23. Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development
    Marina Kazantseva, Ramona A. Eiholzer, Sunali Y. Mehta, Ahmad J. Taha, Sara Bowie, Imogen M. Roth, Jean Zhou, Sebastien M. Joruiz, Janice A. Royds, Noelyn Anne Hung et al. · 2018 · The Journal of Pathology
  24. Aberrant splicing of the DMP1 ‐ ARF ‐ MDM2 ‐p53 pathway in cancer
    Kazushi Inoue, Elizabeth A. Fry · 2016 · International Journal of Cancer
  25. The Δ133p53 Isoforms, Tuners of the p53 Pathway
    Sebastien M. Joruiz, Jessica A. Beck, Izumi Horikawa, Curtis C. Harris · 2020 · Cancers
  26. The Δ133p53 isoform and its mouse analogue Δ122p53 promote invasion and metastasis involving pro-inflammatory molecules interleukin-6 and CCL2
    Imogen M. Roth, H Campbell, César N. Cortés-Rubio, Claire Vennin, Michelle Wilson, Anna K. Wiles, G Williams, Adele G. Woolley, Paul Timpson, Michael V. Berridge et al. · 2016 · Oncogene
  27. PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA
    Kimiyoshi Yano, Ryou‐u Takahashi, Bunsyo Shiotani, Junko Abe, Tomoki Shidooka, Yuki Sudo, Yusuke Yamamoto, Shisei Kan, Hiroki Sakagami, Hidetoshi Tahara · 2021 · Journal of Biological Chemistry
  28. p53 Isoforms as Cancer Biomarkers and Therapeutic Targets
    Liuqun Zhao, Suparna Sanyal · 2022 · Cancers
  29. p53 governs telomere regulation feedback too, via TRF2
    Izumi Horikawa, Kaori Fujita, Curtis C. Harris · 2011 · Aging
  30. Correlation between microRNA-34a levels and lens opacity severity in age-related cataracts
    Ke‐Hung Chien, S-J Chen, Liu H, H-M Chang, Lin‐Chung Woung, C-M Liang, JT Chen, T-J Lin, S-H Chiou, C-H Peng · 2013 · Eye
  31. The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway
    Uma Karthika Rajarajacholan, Subhash Thalappilly, Karl T. Riabowol · 2013 · PLoS Biology
  32. The p53 isoforms are differentially modified by Mdm2
    Suzanne Camus, Sergio Ménendez, Kenneth Fernandes, Nelly Kua, Geng Liu, Dimitris P. Xirodimas, David Philip Lane, Jean‐Christophe Bourdon · 2012 · Cell Cycle
  33. The nuclear factor erythroid 2-related factor 2/p53 axis in breast cancer
    Hadi Fakheri, Mir Amirhossein Sajadi, Ahmad Afrashteh, Wenbiao Ma, Lei Xia, Mohammad Valilo · 2023 · Biochemia Medica
  34. Targeting the JAK-STAT pathway in colorectal cancer: mechanisms, clinical implications, and therapeutic potential
    Penghui Li, Di Huang · 2024 · Frontiers in Cell and Developmental Biology
  35. A Study of TP53 RNA Splicing Illustrates Pitfalls of RNA-seq Methodology
    Sunali Y. Mehta, Peter Tsai, Annette Lasham, Hamish G. Campbell, Roger R. Reddel, Antony W. Braithwaite, Cristin Gregor Print · 2016 · Cancer Research
  36. Influenza A Viruses Control Expression of Proviral Human p53 Isoforms p53β and Δ133p53α
    Olivier Terrier, Virginie Marcel, Gaëlle Cartet, David Philip Lane, Bruno Lina, Manuel Rosa‐Calatrava, Jean‐Christophe Bourdon · 2012 · Journal of Virology
  37. Cellular senescence in chronic obstructive pulmonary disease: Molecular mechanisms and therapeutic interventions
    Sapana Subedi, Mounika Guntipally, Newton Suwal, Rajan Thapa, Saroj Bashyal, Nisha Panth, Gaurav Gupta, Ronan J. MacLoughlin, Brian Gregory George Oliver, Kamal Dua et al. · 2025 · Ageing Research Reviews
  38. Role of senescence and mitotic catastrophe in cancer therapy
    Richa Singh, Jasmine George, Yogeshwer Shukla · 2010 · Cell Division · Retracted
  39. Identification of nonsense-mediated mRNA decay pathway as a critical regulator of p53 isoform β
    Lauren E. Cowen, Yi Tang · 2017 · Scientific Reports
  40. Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells
    Abdul Matin Mondal, Hua Zhou, Izumi Horikawa, Frank A. Suprynowicz, Guangzhao Li, Aleksandra Dakic, Bernard Rosenthal, Lin Ye, Curtis C. Harris, Richard Schlegel et al. · 2018 · Cell Death and Disease
  41. Antibiotics that target mitochondria extend lifespan in C. elegans
    Gloria Bonuccelli, Darren R. Brooks, Sally Shepherd, Federica Sotgia, Michael P. Lisanti · 2023 · Aging
  42. Reduced RNA turnover as a driver of cellular senescence
    Nowsheen Mullani, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickaël Costallat, Éric Batsché, Michèle Goodhardt, Giovanni Cenci, Carl Mann, Christian Muchardt · 2021 · Life Science Alliance
  43. LncRNA Sirt1-AS upregulates Sirt1 to attenuate aging related deep venous thrombosis
    Zhenkai Lou, Jinwen Zhu, Xing Li, Li X, Kaili Du, Bing Wang, Fan Zhang, Xinliang Zhang · 2021 · Aging
  44. Iron deficiency exacerbates cisplatin- or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage
    Shifeng Zhao, Xueqiao Wang, Xiaoqing Zheng, Liang Xiu, Zhigang Wang, Juanlian Zhang, Xudong Zhao, Shougang Zhuang, Qiuhui Pan, Fenyong Sun et al. · 2021 · Free Radical Biology and Medicine
  45. Impaired Cdc20 signaling promotes senescence in normal cells and apoptosis in non–small cell lung cancer cells
    Daniela Volonté, Morgan Sedorovitz, Ferruccio Galbiati · 2022 · Journal of Biological Chemistry
  46. The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer
    H C Moore, Lee B. Jordan, Susan E. Bray, L Baker, Philip Quinlan, Colin A. Purdie, Alastair Mark Thompson, Jean‐Christophe Bourdon, Frances V. Fuller-Pace · 2010 · Oncogene
  47. Modulation of alternative splicing contributes to cancer development: focusing on p53 isoforms, p53β and p53γ
    Hilla Solomon, Michal Sharon, Varda Rotter · 2014 · Cell Death and Differentiation
  48. Influence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers
    Katharina Bischof, Stian Knappskog, Sigrun M. Hjelle, Ingunn M. Stefansson, Kathrine Woie, Helga Birgitte Salvesen, Bjørn Tore Gjertsen, Line Bjørge · 2019 · Scientific Reports
  49. Differential Impacts of Alternative Splicing Networks on Apoptosis
    Jung-Chun Lin, Mei-Fen Tsao, Ying‐Ju Lin · 2016 · International Journal of Molecular Sciences
  50. The Underestimated Role of the p53 Pathway in Renal Cancer
    Alessandra Amendolare, Flaviana Marzano, Vittoria Petruzzella, Rosa Anna Vacca, Luisa Guerrini, Graziano Pesole, Elisabetta Sbisà, Apollonia Tullo · 2022 · Cancers
  51. The role of truncated p53 isoforms in the DNA damage response
    Luiza Steffens Reinhardt, Kira Groen, Cheryl Newton, Kelly A. Avery‐Kiejda · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  52. Arginine Methyltransferase PRMT1 Regulates p53 Activity in Breast Cancer
    Li-Ming Liu, Qiang Tang, Xin Hu, Jingjing Zhao, Yuan Zhang, Guoguang Ying, Fei Zhang · 2021 · Life
  53. Expression of p53 protein isoforms predicts survival in patients with multiple myeloma
    Elizabeta A. Rojas, Luis Antonio Corchete, Cristina De Ramón, Patryk Krzemiński, Dalia Quwaider, Ramón García‐Sánz, Joaquín Martínez‐López, Albert Oriol, Laura Rosiñol, Joan Bladé et al. · 2022 · American Journal of Hematology
  54. A novel SRSF3 inhibitor, SFI003, exerts anticancer activity against colorectal cancer by modulating the SRSF3/DHCR24/ROS axis
    Yawen Zhang, Mengmeng Wang, Fanyi Meng, Man Gil Yang, Yinshuang Chen, Xuqin Guo, Weiwei Wang, Yifan Zhu, Yundi Guo, Chunlai Feng et al. · 2022 · Cell Death Discovery
  55. Alpha-Enolase Is Upregulated on the Cell Surface and Responds to Plasminogen Activation in Mice Expressing a ∆133p53α Mimic
    Sonal Sawhney, Kylie A. Hood, Alisha Shaw, Antony W. Braithwaite, Richard Stubbs, Noelyn Anne Hung, Janice A. Royds, Tania L. Slatter · 2015 · PLoS ONE
  56. Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro
    Rafael de Cabo, Lijuan Liu, Ahmed Ali, Nathan D. Price, Jing Zhang, Mingyi Wang, Edward G. Lakatta, Pablo M. Irusta · 2015 · Aging
  57. p53 and its isoforms in DNA double-stranded break repair
    Yuxi Zhang, Wenya Pan, Jun Chen · 2019 · Journal of Zhejiang University SCIENCE B
  58. mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging
    Józefa Węsierska‐Gądek · 2010 · Aging
  59. Oncogene-Induced Senescence and its Role in Tumor Suppression
    Jay Paul Reddy, Yi Li · 2011 · Journal of Mammary Gland Biology and Neoplasia
  60. SPARC-p53: The double agents of cancer
    Denise Camacho, Joana P. Jesus, António M. Palma, Sofia A. Martins, Alexandre Afonso, Maria Leonor Peixoto, Christopher James Pelham, Eduardo Moreno, Rajan Gogna · 2020 · Advances in cancer research
  61. Δ133p53α Protects Human Astrocytes from Amyloid-beta Induced Senescence and Neurotoxicity
    Kyra Ungerleider, Jessica A. Beck, Delphine Lissa, Sebastien M. Joruiz, Izumi Horikawa, Curtis C. Harris · 2021 · Neuroscience
  62. Does Δ133p53 isoform trigger inflammation and autoimmunity?
    Hamish G. Campbell, Tania L. Slatter, Aaron R. Jeffs, Reena Mehta, Carina Rubio, Margaret A. Baird, Antony W. Braithwaite · 2012 · Cell Cycle
  63. Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant
    Tania L. Slatter, Noelyn Anne Hung, Sara Bowie, H Campbell, Carlos Rubio‐Terres, Daniel Speidel, Michelle Wilson, Margaret A. Baird, Janice A. Royds, Antony W. Braithwaite · 2015 · Cell Death and Disease
  64. miR-34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3
    Wu Xiang, Haotian Lin, Qilin Wang, Wan Chen, Zhaochuan Liu, Hui Chen, Hui Zhang, Weirong Chen · 2016 · Molecular Medicine Reports
  65. p53, stem cell biology and childhood blastomas
    Lixian Oh, Hind Hafsi, Pierre L. Hainaut, Hany Ariffin · 2019 · Current Opinion in Oncology
  66. CUT Domain Proteins in DNA Repair and Cancer
    Zubaidah M. Ramdzan, Elise Vickridge, Camila Cristina Fraga Faraco, Alain Nepveu · 2021 · Cancers
  67. High expression of the p53 isoform γ is associated with reduced progression-free survival in uterine serous carcinoma
    Katharina Bischof, Stian Knappskog, Ingunn M. Stefansson, Emmet McCormack, Jone Trovik, Henrica M.J. Werner, Kathrine Woie, Bjørn Tore Gjertsen, Line Bjørge · 2018 · BMC Cancer
  68. Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α
    Christopher Roselle, Izumi Horikawa, Linhui Chen, Andre R. Kelly, Donna M. Gonzales, Tong Da, Nils Wellhausen, Philipp C. Rommel, Daniel Baker, Megan M. Suhoski et al. · 2024 · Proceedings of the National Academy of Sciences
  69. Targeting the Δ133p53 isoform can restore chemosensitivity in 5-fluorouracil-resistant cholangiocarcinoma cells
    NICHAPAVEE NUTTHASIRIKUL, Chariya Hahnvajanawong, Anchalee Techasen, Temduang Limpaiboon, Chanvit Leelayuwat, Siri Chau‐in, Patcharee Jearanaikoon · 2015 · International Journal of Oncology
  70. Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
    Z Milićević, Vladan Bajić, Lada Živković, Jelena Kasapović, Uroš Andjelković, Biljana Spremo‐Potparević · 2014 · The Scientific World JOURNAL
  71. Detecting p53 Isoforms at Protein Level
    Marcel, Virginie, Khoury, Marie P., Fernandes, Kenneth, Diot, Alexandra, Lane, David P., Bourdon, Jean-Christophe · 2013 · Methods in Molecular Biology
  72. Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA
    Guanglin Niu, Isabel Hellmuth, Tatiana Flisikowska, Hubert Pausch, Beate Rieblinger, Alexander Rinke Carrapeiro, Benjamin Schade, Brigitte Böhm, Eva Kappe, Konrad Fischer et al. · 2021 · Oncogene
  73. Age-Related Alternative Splicing: Driver or Passenger in the Aging Process?
    Marco Baralle, Maurizio Romano · 2023 · Cells
  74. Metabolic pathways regulated by TAp73 in response to oxidative stress
    Massimiliano Agostini, Margherita Annicchiarico‐Petruzzelli, Gerry Melino, Alessandro Rufini · 2016 · Oncotarget
  75. Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles
    Lixian Oh, Pierre L. Hainaut, Sandrine Blanchet, Hany Ariffin · 2020 · BMC Cancer
  76. p53/p73 Protein Network in Colorectal Cancer and Other Human Malignancies
    Anđela Horvat, Ana Tadijan, Ignacija Vlašić, Neda Slade · 2021 · Cancers
  77. What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer?
    Liam Hayman, Wajeeh Raza Chaudhry, В. В. Ревин, Nikolai Zhelev, Jean‐Christophe Bourdon · 2018 · Expert Review of Molecular Diagnostics
  78. Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
    Luiza Steffens Reinhardt, Xiajie Zhang, Kira Groen, Brianna C. Morten, Geoffry Nunzio De Iuliis, Antony W. Braithwaite, Jean‐Christophe Bourdon, Kelly A. Avery‐Kiejda · 2022 · Cell Death and Disease
  79. Detecting and Quantifying p53 Isoforms at mRNA Level in Cell Lines and Tissues
    Marie P. Khoury, Virginie Marcel, Kenneth Fernandes, Alexandra Diot, David Philip Lane, Jean‐Christophe Bourdon · 2012 · Methods in molecular biology
  80. Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes
    Sunali Y. Mehta, Brianna C. Morten, Jisha Antony, Luke Henderson, Annette Lasham, Hamish G. Campbell, Heather E. Cunliffe, Julia A. Horsfield, Roger R. Reddel, Kelly A. Avery‐Kiejda et al. · 2018 · Oncotarget
  81. A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation
    Marina Kazantseva, Sunali Y. Mehta, Ramona A. Eiholzer, Noelyn Anne Hung, Anna K. Wiles, Tania L. Slatter, Antony W. Braithwaite · 2018 · Mammalian Genome
  82. Fidelity of a PDX-CR model for bladder cancer
    Abdul Matin Mondal, Ai‐Hong Ma, Guangzhao Li, Ewa Krawczyk, Ruan Yuan, Jie Lu, Richard Schlegel, Lambros Stamatakis, Keith J. Kowalczyk, George K. Philips et al. · 2019 · Biochemical and Biophysical Research Communications
  83. p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis
    Shengfan Ye, Ting Zhao, Wei Zhang, Zimu Tang, Ce Gao, Zhipeng Ma, Jing‐Wei Xiong, Jinrong Peng, Wei‐Qiang Tan, Jun Chen · 2020 · Cell Death and Disease
  84. Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model
    Sean Miller, Jenna C. Glatzer, Yi-chun Hsieh, Jeffrey D. Rothstein · 2018 · Journal of Neurogenetics
  85. Loss-of-function of p53 isoform Δ113p53 accelerates brain aging in zebrafish
    Ting Zhao, Shengfan Ye, Zimu Tang, Liwei Guo, Zhipeng Ma, Yuxi Zhang, Chun Yang, Jinrong Peng, Jun Chen · 2021 · Cell Death and Disease
  86. Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control
    Ananya Chakravarti, Heshani N Thirimanne, Savanna Brown, Brian R. Calvi · 2021 · eLife
  87. p53 Protein Isoforms: Key Regulators in the Front Line of Pathogen Infections?
    Olivier Terrier, Jean‐Christophe Bourdon, Manuel Rosa‐Calatrava · 2013 · PLoS Pathogens
  88. P53 protein overexpression in de novo acute myeloid leukemia patients with normal diploid karyotype correlates with FLT3 internal tandem duplication and worse relapse‐free survival
    Rita Elias Assi, Hatice Deniz Gur, Sanam Loghavi, Sergej Naumovich Konoplev, Marina Y Konopleva, Naval Guastad Daver, Mehrnoosh Tashakori, Tapan Mahendra Kadia, Mark J. Routbort, Alireza Salem et al. · 2018 · American Journal of Hematology
  89. The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures
    Leïla T. S. Fusée, Norman Salomao, Anand Ponnuswamy, Lixiao Wang, Ignacio López, Sa Chen, Xiaolian Gu, Stavros Polyzoidis, Sivakumar Vadivel Gnanasundram, Robin Fåhræus · 2023 · Cell Death and Differentiation
  90. Asymmetric Cell Division and Template DNA Co-Segregation in Cancer Stem Cells
    Sharon R. Pine, Wen‐Yu Liu · 2014 · Frontiers in Oncology
  91. DNA-Damage-Induced Alternative Splicing of p53
    Jing Chen, Dadong Zhang, Xiaodi Qin, Kouros Owzar, Jennifer J. McCann, Michael B. Kastan · 2021 · Cancers
  92. A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation
    Lu Gong, Xiao Pan, Chuan-Bian Lim, Anna de Polo, John B. Little, Zhi-Min Yuan · 2018 · Oncogene
  93. ISRIB inhibits the senescence of type II pulmonary epithelial cells to alleviate pulmonary fibrosis induced by silica in mice
    Yaqian Li, Xu-Liang An, Fuyu Jin, Yi-Fei Bai, Tian Li, Xinyu Yang, Shupeng Liu, Xuemin Gao, Na Mao, Hong Xu et al. · 2023 · Ecotoxicology and Environmental Safety
  94. Discovery of TP53 splice variants in two novel papillary urothelial cancer cell lines
    Annemarie Koch, Jiřı́ Hatina, Harald Rieder, Hans‐Helge Seifert, W. Huckenbeck, Frank Jankowiak, Andrea R. Florl, Robert Stoehr, Wolfgang A. Schulz · 2012 · Cellular Oncology
  95. Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells
    Hongmei Zhang, Xiao-Guang Sang, Yan-Ze Wang, Can Cui, Li Zhang, Wansheng Ji · 2017 · World Journal of Gastroenterology
  96. p53β: a new prognostic marker for patients with clear-cell renal cell carcinoma from 5.3 years of median follow-up
    Haiyang Zhang, Yong Zhao, Peng Sun, Miaoqing Zhao, Zhenhui Su, Xunbo Jin, Wei Song · 2018 · Carcinogenesis
  97. An introduction to genes, genomes and disease
    Peter A. Hall, Jorge Sergio Reis-Filho, Ian P.M. Tomlinson, Richard Poulsom · 2009 · The Journal of Pathology
  98. Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs
    Weili Ma, Yunping Lin, Wanli Xuan, Patrick L. Iversen, L J Smith, Samuel Benchimol · 2011 · Oncogene
  99. Differential effects of diverse p53 isoforms on TAp73 transcriptional activity and apoptosis
    Arijana Zorić, Anđela Horvat, Neda Slade · 2012 · Carcinogenesis
  100. The Therapeutic Potential of the Restoration of the p53 Protein Family Members in the EGFR-Mutated Lung Cancer
    Matilde Fregni, Yari Ciribilli, Joanna Zawacka‐Pankau · 2022 · International Journal of Molecular Sciences