A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

Cited by (290)

Items 101–200 of 290

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3. The Hippo pathway modulates resistance to BET proteins inhibitors in lung cancer cells
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4. Identification, Mechanism of Action, and Antitumor Activity of a Small Molecule Inhibitor of Hippo, TGF-β, and Wnt Signaling Pathways
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5. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism
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6. Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling
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7. Hippo pathway in mammary gland development and breast cancer
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8. KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling
   Yu B, Jun Su, Qiqi Shi, Qing Liu, Jun Ma, Guoqing Ru, Lei Zhang, Jian Zhang, Xichun Hu, Jianming Tang · 2022 · Nature Communications
9. Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond
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10. Roles of the H ippo pathway in lung development and tumorigenesis
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11. Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway
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12. New Insights into YAP/TAZ-TEAD-Mediated Gene Regulation and Biological Processes in Cancer
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13. VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer
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14. Neuronal Hippo signaling: From development to diseases
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15. Metformin suppresses proliferation and invasion of drug‐resistant breast cancer cells by activation of the Hippo pathway
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16. The hippo pathway: A master regulator of liver metabolism, regeneration, and disease
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17. Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system
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18. Identification of the kinase STK25 as an upstream activator of LATS signaling
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19. STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells
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20. High Risk of Hepatocellular Carcinoma Development in Fibrotic Liver: Role of the Hippo-YAP/TAZ Signaling Pathway
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21. Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer
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22. O-GlcNAcylation regulation of cellular signaling in cancer
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23. Hippo‐Yap/Taz signaling: Complex network interactions and impact in epithelial cell behavior
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24. Oncogenic miRNAs and target therapies in colorectal cancer
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25. The Hippo signal transduction network for exercise physiologists
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26. The role of selected non-coding RNAs in the biology of non-small cell lung cancer
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27. LKB1 tumor suppressor: Therapeutic opportunities knock when LKB1 is inactivated
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28. Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization
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29. CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling
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30. LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues
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31. Emerging Perspectives on Leukemia Inhibitory Factor and its Receptor in Cancer
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32. The Tumor Suppressor Kinase LKB1: Metabolic Nexus
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33. Convergence of Calcium Channel Regulation and Mechanotransduction in Skeletal Regenerative Biomaterial Design
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34. Energy sensing and cancer: LKB1 function and lessons learnt from Peutz–Jeghers syndrome
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35. Emerging role of Hippo signalling pathway in bladder cancer
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36. Expression of Polarity Genes in Human Cancer
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37. Research progress in NOS1AP in neurological and psychiatric diseases
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38. TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway
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40. Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance
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41. YAP/TAZ-mediated activation of serine metabolism and methylation regulation is critical for LKB1-deficient breast cancer progression
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42. Regulation of Hippo signaling pathway in cancer: A MicroRNA perspective
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43. Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer’s Disease Pathogenesis?
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44. The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer
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45. Golgi Apparatus Regulates Plasma Membrane Composition and Function
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46. The role of extracellular biophysical cues in modulating the Hippo-YAP pathway
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47. NOS1AP Functionally Associates with YAP To Regulate Hippo Signaling
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48. Yap1-Scribble polarization is required for hematopoietic stem cell division and fate
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49. An Updated Understanding of the Role of YAP in Driving Oncogenic Responses
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50. A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
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51. Canonical and Noncanonical Roles of Par-1/MARK Kinases in Cell Migration
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53. Mst1 positively regulates B-cell receptor signaling via CD19 transcriptional levels
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54. MK5 Regulates YAP Stability and Is a Molecular Target in YAP-Driven Cancers
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57. Development and Therapeutic Potential of NUAKs Inhibitors
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58. LKB1 as a Gatekeeper of Hepatocyte Proliferation and Genomic Integrity during Liver Regeneration
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59. Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis
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60. Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice
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62. MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer
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63. MAGI2/S-SCAM outside brain
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64. The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma
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65. Insights Into the Properties, Biological Functions, and Regulation of USP21
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66. Polarity proteins in oncogenesis
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67. Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity
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68. Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma
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69. Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis
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70. LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer
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74. The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma
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77. Ubiquitination‑deubiquitination in the Hippo signaling pathway (Review)
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78. Interplay of Developmental Hippo–Notch Signaling Pathways with the DNA Damage Response in Prostate Cancer
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79. LKB1 biology: assessing the therapeutic relevancy of LKB1 inhibitors
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80. USP21 regulates Hippo pathway activity by mediating MARK protein turnover
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81. Functional regulation of YAP mechanosensitive transcriptional coactivator by Focused Low-Intensity Pulsed Ultrasound (FLIPUS) enhances proliferation of murine mesenchymal precursors
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83. Fufang Xueshuantong protects retinal vascular endothelial cells from high glucose by targeting YAP
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84. Hippo vs. Crab: tissue‐specific functions of the mammalian Hippo pathway
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90. A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation
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99. DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis
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