Organelle-specific initiation of cell death

Cited by (238)

Items 101–200 of 238

1. Contribution of Mitochondrial Ion Channels to Chemo-Resistance in Cancer Cells
   Roberta Peruzzo, Ildikò Szabó · 2019 · Cancers
2. Feasibility and safety of targeting mitochondria for cancer therapy – preclinical characterization of gamitrinib, a first-in-class, mitochondriaL-targeted small molecule Hsp90 inhibitor
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3. Tumor-targeted supramolecular nanoparticles self-assembled from a ruthenium-β-cyclodextrin complex and an adamantane-functionalized peptide
   Shan-Shan Xue, Cai‐Ping Tan, Mu‐He Chen, Jianjun Cao, Dongyang Zhang, Rui‐Rong Ye, Liang‐Nian Ji, Zong‐Wan Mao · 2016 · Chemical Communications
4. Dual-functional cyclometalated iridium imine NHC complexes: highly potent anticancer and antimetastatic agents
   Zhenzhen Tian, Yuliang Yang, Lihua Guo, Genshen Zhong, Juanjuan Li, Zhe Liu · 2018 · Inorganic Chemistry Frontiers
5. Visualization of mitochondrial membrane potential in mammalian cells
   Noemí Esteras, Merel J.W. Adjobo-Hermans, Andrey Y. Abramov, Werner J.H. Koopman · 2019 · Methods in cell biology
6. Golgi stress–induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing
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7. Altered cytoskeletal organization characterized lethal but not surviving Brtl+/−mice: insight on phenotypic variability in osteogenesis imperfecta
   Laura Bianchi, Assunta Gagliardi, Silvia Maruelli, Roberta Besio, Claudia Landi, Roberta Gioia, Kenneth M. Kozloff, Basma M. Khoury, Paul J. Coucke, Sofie Symoens et al. · 2015 · Human Molecular Genetics
8. Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
   Philippe Pihán, Fernanda Lisbona, Janina E. Borgonovo, Sandra Edwards‐Jorquera, Paula Nunes, Karen Castillo, Oliver Kepp, Hery Urra, Suvi Saarnio, Helena Vihinen et al. · 2021 · Science Advances
9. Cocaine and mitochondria-related signaling in the brain: A mechanistic view and future directions
   Marcos Roberto de Oliveira, Fernanda Rafaela Jardim · 2015 · Neurochemistry International
10. Research on endoplasmic reticulum–targeting fluorescent probes and endoplasmic reticulum stress–mediated nanoanticancer strategies: A review
    Li Qiao, Xinxin Shao, Shi-Jie Gao, Zheng Ming, Xianjun Fu, Qingcong Wei · 2021 · Colloids and Surfaces B Biointerfaces
11. A photoactivatable theranostic probe for simultaneous oxidative stress-triggered multi-color cellular imaging and photodynamic therapy
    Xiaohui Chen, Zicong Zhang, Wenshuai Luo, Zeyan Zhuang, Zujin Zhao, Lei Wang, Dong Wang, Ben Zhong Tang · 2022 · Biomaterials
12. Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells
    Apar Pataer, Bülent Özpolat, RuPing Shao, Neil R. Cashman, Steven Samuel Plotkin, Charles E. Samuel, Steven Hsesheng Lin, Nashwa N. Kabil, Jing Wang, Mourad Majidi et al. · 2019 · Oncogene
13. Engineering Anticancer Amphipathic Peptide-Dendronized Compounds for Highly-Efficient Plasma/Organelle Membrane Perturbation and Multidrug Resistance Reversal
    Xiao Zhang, Yachao Li, Cheng Hu, Yahui Wu, Dan Zhong, Xianghui Xu, Zhongwei Gu · 2018 · ACS Applied Materials & Interfaces
14. Role of BCL-2 Family Proteins in Apoptosis and its Regulation by Nutrients
    Chen Zheng, Ting Liu, Huihui Liu, Jing Wang · 2019 · Current Protein and Peptide Science
15. Quantification of cellular viability by automated microscopy and flow cytometry
    Allan Sauvat, Yidan Wang, Florian Segura, Sabrina Spaggiari, Kévin Müller, Heng Zhou, Lorenzo Galluzzi, Oliver Kepp, Guido Kroemer · 2015 · Oncotarget
16. Trial Watch: Adoptive cell transfer for oncological indications
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17. Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
    Marina Villanueva Paz, Mario David Cordero, Ana Delgado Pavón, Beatriz Castejón‐Vega, David Cotán, Mario de la Mata, Manuel Oropesa-Ávila, Elísabet Alcocer‐Gómez, Isabel de Lavera, Juan Garrido‐Maraver et al. · 2016 · Genes & Cancer
18. Safety evaluation and ibuprofen removal via an Alternanthera philoxeroides-based biochar
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19. Repurposing Cationic Amphiphilic Drugs and Derivatives to Engage Lysosomal Cell Death in Cancer Treatment
    Michelle Hu, Kermit L. Carraway · 2020 · Frontiers in Oncology
20. Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells
    Masanori Hirama, Seiji Isonishi, Makoto Yasuda, Hiroshi Ishikawa · 2006 · Oncology Reports
21. Fluence Rate Determines PDT Efficiency in Breast Cancer Cells Displaying Different GSH Levels
    Ancély Ferreira dos Santos, Daria Raquel Queiroz de Almeida, Letícia Ferreira Terra, Rosangela A.M. Wailemann, Vinícius M. Gomes, Gabriel Santos Arini, Felipe Gustavo Ravagnani, Maurı́cio S. Baptista, Letícia Labriola · 2019 · Photochemistry and Photobiology
22. Extraspecific Manifestation of Nanoheater’s Position Effect on Distinctive Cellular Photothermal Responses
    Thang Do Cong, Zhimin Wang, Ming Hu, Qinyu Han, Bengang Xing · 2020 · ACS Nano
23. Phthalocyanine and Its Formulations: A Promising Photosensitizer for Cervical Cancer Phototherapy
    Lucimara Rodrigues Carobeli, Lyvia Eloiza de Freitas Meirelles, Gabrielle Marconi Zago Ferreira Damke, Edílson Damke, Maria Vitória Felipe de Souza, Natália Lourenço Mari, Kayane Harumi Mashiba, Cristiane Suemi Shinobu Mesquita, Raquel Pantarotto Souza, Vânia Ramos Sela da Silva et al. · 2021 · Pharmaceutics
24. Organic Selenium induces ferroptosis in pancreatic cancer cells
    Roberta Noè, N. Inglese, Patrizia Romani, Thauan Serafini, C. Paoli, Beatrice Calciolari, Marco Fantuz, Agata Zamborlin, N. C. Surdo, Vittoria Spada et al. · 2023 · Redox Biology
25. Canthin-6-one induces cell death, cell cycle arrest and differentiation in human myeloid leukemia cells
    Heron Fernandes Vieira Torquato, Antonio Carlos Ribeiro-Filho, Marcus V. Buri, Roberto Theodoro de Araujo Júnior, Renata Pimenta, José Salvador Rodrigues de Oliveira, Valdir Cechinel Filho, Antonio Macho, Edgar Julian Paredes‐Gamero, Domingos Tabajara de Oliveira Martins · 2017 · Biochimica et Biophysica Acta (BBA) - General Subjects
26. Mitochondria in cancer: clean windmills or stressed tinkerers?
    Dario C. Altieri · 2022 · Trends in Cell Biology
27. A Christianson syndrome-linked deletion mutation (∆287ES288) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death
    Alina Ilie, Andy Y. L. Gao, Jonathan Reid, Annie Boucher, Cassandra McEwan, Hervé Barrière, Gergely L. Lukács, Rebecca Anne McKinney, John Orlowski · 2016 · Molecular Neurodegeneration
28. Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer
    Yadi Geng, Chao Zhang, Jian-Li Lei, Pei Yu, Yuan‐Zheng Xia, Hao Zhang, Lei Yang, Ling‐Yi Kong · 2017 · Biochemical Pharmacology
29. Nano CaCO3 “Lysosomal Bombs” Enhance Chemotherapy Drug Efficacy via Rebalancing Tumor Intracellular pH
    Chenxu Zhang, Shihui Li, Ao Yu, Yongjian Wang · 2019 · ACS Biomaterials Science & Engineering
30. Colorectal cancer and adjacent normal mucosa differ in apoptotic and inflammatory protein expression
    Xiaojing Sun, Zhonghua Xue, Aqeela Yasin, Yingkun He, Yaru Chai, Jingan Li, Kun Zhang · 2021 · Engineered Regeneration
31. Comparison of the radiotoxicity of the 99mTc-labeled compounds 99mTc-pertechnetate, 99mTc-HMPAO and 99mTc-MIBI
    Ute Maucksch, Roswitha Runge, Gerd Wunderlich, Robert Freudenberg, Anne Naumann, Jörg Kotzerke · 2016 · International Journal of Radiation Biology
32. 4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis
    Yun-dong You, Wenhong Deng, Wenyi Guo, Liang Zhao, Fangchao Mei, Yu-pu Hong, Yu Zhou, Jia Yu, Sheng Xu, Weixing Wang · 2019 · Digestive Diseases and Sciences
33. CO/light dual-activatable Ru( ii )-conjugated oligomer agent for lysosome-targeted multimodal cancer therapeutics
    Min Yang, Hao Zhao, Ziqi Zhang, Qiong Yuan, Qian Feng, Xinrui Duan, Shu Wang, Yanli Tang · 2021 · Chemical Science
34. Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths
    Dipanjan Karati, Shreyasi Meur, Swarupananda Mukherjee, Souvik Roy · 2024 · Coordination Chemistry Reviews
35. Association of tamoxifen resistance and lipid reprogramming in breast cancer
    Susanne Hultsch, Matti Kankainen, Lassi Paavolainen, Ruusu‐Maaria Kovanen, Elina Ikonen, Sara Kangaspeska, Vilja M. Pietiäinen, Olli Kallioniemi · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
36. The cyclopeptide <alpha>-amatoxin induced hepatic injury via the mitochondrial apoptotic pathway associated with oxidative stress
    Xiao Chen, Bing Shao, Chengmin Yu, Qunmei Yao, Ma Peibin, Weiwei Li, Wenjian Cai, Hao Fu, Bin Li, Chengye Sun · 2020 · Peptides
37. Asymmetric AB3 Miktoarm Star Polymers: Synthesis, Self‐Assembly, and Study of Micelle Stability Using AF4 for Efficient Drug Delivery
    Alexandre Moquin, Anjali Sharma, Yiming Cui, Anthony Lau, Dušica Maysinger, Ashok K. Kakkar · 2015 · Macromolecular Bioscience
38. Defective Autophagy Initiates Malignant Transformation
    Lorenzo Galluzzi, José Manuel Bravo‐San Pedro, Guido Kroemer · 2016 · Molecular Cell
39. Genetically Encoded Fluorescent Probe for Imaging Apoptosis in Vivo with Spontaneous GFP Complementation
    Yusuke Nasu, Y. Asaoka, Misako Namae, Hiroshi Nishina, Hideaki� Yoshimura, Takeaki Ozawa · 2015 · Analytical Chemistry
40. TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway
    Guodong Yang, Xiaoying Zhang · 2021 · Saudi Journal of Gastroenterology
41. Cell death signaling in human erythron: erythrocytes lose the complexity of cell death machinery upon maturation
    Anton S. Tkachenko, Ondřej Havránek · 2025 · APOPTOSIS
42. Quality and Quantity Control of Mitochondria Injection Into Single Cells With Robot-Aided Micro-Manipulation System
    Adnan Shakoor, Mingyang Xie, Wendi Gao, Muhammad Majid Gulzar, Jiayu Sun, Dong Bai Sun · 2023 · IEEE Transactions on Automation Science and Engineering
43. Trial Watch: Proteasomal inhibitors for anticancer therapy
    Florine Obrist, Gwenola Manic, Guido Kroemer, Ilio Vitale, Lorenzo Galluzzi · 2014 · Molecular & Cellular Oncology
44. A Heteroleptic/Trimetallic Os II –Ru II –Zn II Sierpiński Triangle for Efficient Photodynamic Therapy of Hypoxic Tumors Mainly through Type I Mechanism
    Huan Qin, Qiaolin Chen, Bangtang Chen, Jun Wang, Huilin Su, Xiaojie Huang, Qiangqiang Dong, Mingzhao Chen, Zhimin Jiang, Ying‐Ying Li et al. · 2025 · Journal of the American Chemical Society
45. Anticancer polypyrrole-polyethylenimine drug-free nanozyme for precise B-cell lymphoma therapy
    Thi Thuy Dung Nguyen, Er‐Yuan Chuang, Yaping Chen, Po‐Chun Tseng, Ming-Kai Jhan, Chun-Yi Lai, Yung-Ting Wang, Yu-Ping Hung, Chun A. Changou, Chi‐Ming Lee et al. · 2023 · Biomedicine & Pharmacotherapy
46. Autophagy protects against Cd-induced cell damage in primary chicken hepatocytes via mitigation of oxidative stress and endoplasmic reticulum stress
    Nan Li, Bao‐Jin Yi, Muhammad Asmat Ullah Saleem, Xue‐Nan Li, Jin‐Long Li · 2023 · Ecotoxicology and Environmental Safety
47. Lysosome-Anchoring Activation Design of Type I Photosensitizer Evokes Pyroptosis and Antitumor Immunity
    Guo Li, Liuwei Gu, Chaojie Yang, Xiaojie Kong, Yuling Qin, Li Jun Wu · 2024 · ACS Materials Letters
48. Toxicological Risk Assessment of Emerging Nanomaterials: Cytotoxicity, Cellular Uptake, Effects on Biogenesis and Cell Organelle Activity, Acute Toxicity and Biodistribution of Oxide Nanoparticles
    Lionel Maurizi, Anne‐Laure Papa, Julien Boudon, Sruthi Sudhakaran, Benoist Pruvot, David Vandroux, Johanna Chluba, Gérard Lizard, Nadine Millot · 2018 · InTech eBooks
49. Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia–reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway
    Shuai Jiang, Qizhong Fan, Ming qing Xu, Fengchun Cheng, Zhihui Li, Guojian Ding, Lei Geng, Tingliang Fu · 2020 · Journal of Pediatric Surgery
50. Effects of xylazine and dexmedetomidine on equine articular chondrocytes in vitro
    Francesco Mancini, Sara Nannarone, Sandra Buratta, Giuseppina Ferrara, Anna Maria Stabile, Matteo Vuerich, Isabella Santinelli, Alessandra Pistilli, Elisabetta Chiaradia · 2017 · Veterinary Anaesthesia and Analgesia
51. Lysosome-Dependent Necrosis Specifically Evoked in Cancer Cells by Gold Nanorods
    Fulei Zhang, Di Chen, Ying Wang, Li Zhang, Wei Dong, Jianxin Dai, Chong Jin, Xia Dong, Yun Hui Sun, He Zhao et al. · 2017 · Nanomedicine
52. Cigarette smoke condensate may disturb immune function with apoptotic cell death by impairing function of organelles in alveolar macrophages
    Eun‐Jung Park, Hong-Soo Lee, Sang Jin Lee, Yoo-Jin Park, Son-Il Park, Jaerak Chang, Kyuhong Lee · 2018 · Toxicology in Vitro
53. Dual-channel fluorescent probe bearing two-photon activity for cell viability monitoring
    Yanqian Zhao, Chengkai Zhang, Jiejie Liu, Dandan Li, Xiaohe Tian, Aidong Wang, Shengli Li, Jieying Wu, Yupeng Tian · 2019 · Journal of Materials Chemistry B
54. Facile Green Synthesis of New Chitosan-Metal Nanoparticles as Nano-Agrofungicide For The Preservation of Postharvest Cherry Fruits
    Onome Ejeromedoghene, Abiodun Oladipo, Olayinka Oderinde, Emmanuel Sunday Okeke, Saliu Alao Amolegbe, Tolulope Mobolaji Obuotor, Caroline Avosuahi Akinremi, Sheriff Adewuyi, Guodong Fu · 2021 · ACS Agricultural Science & Technology
55. Lysosome-targeted cyclometalated iridium(III) complexes: JMJD inhibition, dual induction of apoptosis, and autophagy
    Junjian Lu, Xiu-Rong Ma, Kai Ming Xie, Mei‐Ru Chen, Bo Huang, Rong‐Tao Li, Rui‐Rong Ye · 2022 · Metallomics
56. Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors
    Guido Kroemer, Lorenzo Galluzzi · 2016 · Oncotarget
57. Liposome as drug delivery system enhance anticancer activity of iridium (III) complex
    Yiying Gu, Lan Bai, Yuanyuan Zhang, Huiwen Zhang, De-Gang Xing, Tian Xiang Li, Yi Zhou, Jing Hao, Yun‐Jun Liu · 2020 · Journal of Liposome Research
58. Unfolded protein response in the activation-induced biological processes of CD8+ T cells
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59. Perinatal nicotine exposure alters Akt/GSK-3β/mTOR/autophagy signaling, leading to development of hypoxic-ischemic-sensitive phenotype in rat neonatal brain
    Yong Hui Li, Andrew M. Song, Yingjie Fu, Andrew Walayat, Meizi Yang, Jie Jian, Bailin Liu, Liang Ping Xia, Li Zhang, Daliao Xiao · 2019 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
60. Channels and transporters for inorganic ions in plant mitochondria: Prediction and facts
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61. Autophagy flux inhibition mediated by lysosomal dysfunction participates in the cadmium exposure‐induced cardiotoxicity in swine
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62. The Importance of Being Dead: Cell Death Mechanisms Assessment in Anti-Sarcoma Therapy
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63. Insights into the Theranostic Activity of Nonoxido VIV: Lysosome-Targeted Anticancer Metallodrugs
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64. Intracellular delivery and photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles
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65. An endoplasmic reticulum targeted NIR-AIE fluorescent probe with superior photostability for accelerating oxidative stress to trigger cancer cells apoptosis
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66. Two-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models
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67. High‐content analysis boosts identification of the initial cause of triptolide‐induced hepatotoxicity
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68. Novel function of cytoplasmic p53 at the interface between mitochondria and the endoplasmic reticulum
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69. Targeted Photoredox System under a Hypoxic Environment to Evoke Photodynamic Immunotherapy
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70. Cell ageing: a flourishing field for neurodegenerative diseases
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71. Cell Death, by Any Other Name…
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72. The Proapoptotic Gene Bad Regulates Brain Development via p53-Mediated Stress Signals in Zebrafish
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73. Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression
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74. The metabolic basis of regulated cell death
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75. Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
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76. Modulation of pro-apoptotic effects and mitochondrial potential on B16F10 cells by DODAC/PHO-S liposomes
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77. Iron-dependent lysosomal dysfunction mediated by a natural product hybrid
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78. Brief exposure to nanosized and bulk titanium dioxide forms induces subtle changes in human D384 astrocytes
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79. Necrosis: Linking the Inflammasome to Inflammation
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80. The induction of apoptosis in BEL-7402 cells by an iridium(III) complex through lysosome–mitochondria pathway
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81. Internal perspectivalism: the solution to generality problems about proper function and natural norms
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82. Dasatinib and interferon alpha synergistically induce pyroptosis-like cell death in philadelphia chromosome positive acute lymphoblastic leukemia.
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83. PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics
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84. Amyotrophic Lateral Sclerosis: Focus on Cytoplasmic Trafficking and Proteostasis
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85. Detection of Apoptotic Versus Autophagic Cell Death by Flow Cytometry
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86. CK2: A Global Regulator of Cell Death
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87. Preface: Endoplasmic reticulum in health and disease
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88. GABARAP is a determinant of apoptosis in growth-arrested chicken embryo fibroblasts
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89. Exposure to Ozone Downregulates Bcl-2 and Increases Executing Caspases-3 and -8 in the Hippocampus, Frontal Cortex, and Cerebellum of Rats
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90. Lysosome‐Targeted Bifunctional Therapeutics Induce Autodynamic Cancer Therapy
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91. Molecular targets of chloropicrin in human airway epithelial cells
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92. Pathophysiology of Cancer Cell Death
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93. Only one carbon difference determines the pro‐apoptotic activity of α‐tocopheryl esters
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94. Dual-/multi-organelle-targeted AIE probes associated with oxidative stress for biomedical applications
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95. Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish
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96. Autoschizis: A Mode of Cell Death of Cancer Cells Induced by a Prooxidant TreatmentIn VitroandIn Vivo
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97. Turning Tumor Acidosis into a Therapeutic Advantage with Nanomedicine
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98. Mononuclear Nonoxido vs Dinuclear Oxido V IV Metallodrugs: Solution Behavior, Biomolecular Binding, Cytotoxicity, and Internalization in Cells
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99. Effect of ONC201 Antitumor Drug on the Number of Mitochondrial Nucleoids in BT474 Breast Cancer Cells in Culture
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100. Cigarette smoke extract may induce lysosomal storage disease‐like adverse health effects
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