Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

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Items 201–300 of 435

1. Functional and mechanistic analysis of telomerase: An antitumor drug target
   Yinnan Chen, Yanmin Zhang · 2016 · Pharmacology & Therapeutics
2. Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity
   Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Sahn-Ho Kim, Kirit R. Pindolia, Ali S. Arbab, Subhash C. Gautam · 2012 · Biochemical and Biophysical Research Communications
3. RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma
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4. Noncoding RNAs in Vascular Aging
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5. Complement anaphylatoxins C3a and C5a induce a failing regenerative program in cardiac resident cells. Evidence of a role for cardiac resident stem cells other than cardiomyocyte renewal
   David Lara‐Astiaso, Alberto Izarra, Juan Camilo Estrada, Carmen Albo, Isabel Moscoso, Enrique Samper, Javier Moncayo, Abelardo Solano, António Bernad, Antonio Díez‐Juan · 2012 · SpringerPlus
6. Effects of Mitochondrial Translocation of Telomerase on Drug Resistance in Hepatocellular Carcinoma Cells
   Jing Yan, Yuan Zhou, DaiXing Chen, Lili Li, Xin Xiang Yang, Yang You, Xianlong Ling · 2015 · Journal of Cancer
7. Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCα
   Shankar Jagadeesh, Partha P. Banerjee · 2006 · Biochemical and Biophysical Research Communications
8. Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma
   Edith Chevret, Lætitia Andrique, Martina Prochazkova‐Carlotti, Jacky Ferrer, David Cappellen, Elodie Laharanne, Yamina Idrissi, Anna Boettiger, Wafa Sahraoui, Florian Ruiz et al. · 2014 · Blood
9. PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK)
   P.K. Senthilkumar, Larry W. Robertson, Gabriele Ludewig · 2011 · Toxicology and Applied Pharmacology
10. Cardiac telomere length in heart development, function, and disease
    Scott A. Booth, Fadi Joseph Charchar · 2017 · Physiological Genomics
11. Method validation of in vitro RNA transcript analysis on the Agilent 2100 Bioanalyzer
    Bruce I. Sodowich, Irini Fadl, Craig Burns · 2007 · Electrophoresis
12. Telomerase-Associated Apoptotic Events by MushroomGanoderma lucidumon Premalignant Human Urothelial Cells
    John W. M. Yuen, Mayur Danny I. Gohel, Doris W.T. Au · 2007 · Nutrition and Cancer
13. Multiple mechanisms of cell death induced by chelidonine in MCF-7 breast cancer cell line
    Sakineh Kazemi Noureini, Hosein Esmaili · 2014 · Chemico-Biological Interactions
14. αCP1 Mediates Stabilization of hTERT mRNA by Autocrine Human Growth Hormone
    Bright Starling Emerald, Yong Chen, Tao Zhu, Zhe Zhu, Kok‐Onn Lee, Peter D. Gluckman, Peter Edward Lobie · 2006 · Journal of Biological Chemistry
15. Ets2 transcription factor, telomerase activity and breast cancer
    Julie Dwyer, Junping Liu · 2009 · Clinical and Experimental Pharmacology and Physiology
16. Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer
    Lia E. De Faveri, C D Hurst, F M Platt, C F Taylor, J-A Roulson, Marta Sänchez‐Carbayo, Margaret A. Knowles, Emma Chapman · 2013 · British Journal of Cancer
17. MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-κB pathway
    Ahmad Fatemi, Majid Safa, Ahmad Kazemi · 2015 · Tumor Biology
18. Inhibition of UBE2D3 Expression Attenuates Radiosensitivity of MCF-7 Human Breast Cancer Cells by Increasing hTERT Expression and Activity
    Wenbo Wang, Lei Yang, Hu Liu, Fen Li, Li Mei Ren, Haijun Yu, Yu Liu, Ling Xia, Lei Han, Zhengkai Liao et al. · 2013 · PLoS ONE
19. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes
    Zahra Ameri, Saeedeh Ghiasi, Alireza Farsinejad, Gholamhossein Hassanshahi, Mohsen Ehsan, Ahmad Fatemi · 2019 · Life Sciences
20. Imaging Epidermal Growth Factor Receptor Phosphorylation in Human Colorectal Cancer Cells and Human Tissues
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21. Modeling aging and cancer in the telomerase knockout mouse
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22. hTERT Extends Proliferative Lifespan and Prevents Oxidative Stress-Induced Apoptosis in Human Lens Epithelial Cells
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23. Telomeres and Telomerase: A Modern Fountain of Youth?
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24. The telomerase cycle: normal and pathological aspects
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25. Role of angiotensin II in aging
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26. Role of telomerase in the tumour microenvironment
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27. Telomerase reverse transcriptase: A novel neuroprotective mechanism involved in neonatal hypoxic‐ischemic brain injury
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28. Correlation of dyskerin expression with active proliferation independent of telomerase
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29. Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics
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30. The Molecular Interplay between Human Oncoviruses and Telomerase in Cancer Development
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31. Tissue-Engineered Allograft Intervertebral Disc Transplantation for the Treatment of Degenerative Disc Disease: Experimental Study in a Beagle Model
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32. Telomerase reverse transcriptase potentially promotes the progression of oral squamous cell carcinoma through induction of epithelial-mesenchymal transition
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33. The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa
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34. Upregulation of mtSSB by interleukin‐6 promotes cell growth through mitochondrial biogenesis‐mediated telomerase activation in colorectal cancer
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35. Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers
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36. Marked telomere shortening in mobilized peripheral blood progenitor cells (PBPC) following two tightly spaced high-dose chemotherapy courses with G-CSF
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37. Dissecting the non-canonical functions of telomerase
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38. Human Telomerase Reverse Transcriptase (hTERT) Positively Regulates 26S Proteasome Activity
    Eunju Im, Jong Bok Yoon, Han‐Woong Lee, Kwang Chul Chung · 2016 · Journal of Cellular Physiology
39. Means to the ends: The role of telomeres and telomere processing machinery in metastasis
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40. Breast Field Cancerization: Isolation and Comparison of Telomerase-Expressing Cells in Tumor and Tumor Adjacent, Histologically Normal Breast Tissue
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41. Improving cell therapy—experiments using transplanted telomerase-immortalized cells in immunodeficient mice
    Qin Huang, Meizhen Chen, Sitai Liang, Victor Acha, Dan Liu, Furong Yuan, Christina L. Hawks, Peter J. Hornsby · 2006 · Mechanisms of Ageing and Development
42. Human fibroblasts expressing hTERT show remarkable karyotype stability even after exposure to ionizing radiation
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43. Canonical and extra‐telomeric functions of telomerase: Implications for healthy ageing conferred by endurance training
    Joshua Denham · 2023 · Aging Cell
44. Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects
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45. Validation of tissue-specific promoter-driven tumor-targeting trans-splicing ribozyme system as a multifunctional cancer gene therapy device in vivo
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46. Systematic Review of Genetic Variation in Chromosome 5p15.33 and Telomere Length as Predictive and Prognostic Biomarkers for Lung Cancer
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47. Anaplastic and poorly differentiated thyroid carcinomas: genetic evidence of high‐grade transformation from differentiated thyroid carcinoma
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48. New surprises from an old favourite: The emergence of telomerase as a key player in the regulation of cancer stemness
    Kerem Teralı, Açelya Yılmazer · 2015 · Biochimie
49. Telomerase: The Devil Inside
    Mukesh Kumar, André Lechel, Çagatay Güneş · 2016 · Genes
50. Therapeutic applications of group I intron‐based trans‐splicing ribozymes
    Chang Ho Lee, Seung Ryul Han, Seong‐Wook Lee · 2018 · Wiley Interdisciplinary Reviews - RNA
51. Molecular targets in cancer prevention by 4-(methylthio)butyl isothiocyanate - A comprehensive review
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52. PinX1: structure, regulation and its functions in cancer
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53. Telomerase Deficiency in Bone Marrow–Derived Cells Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation
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54. Adenoviral Human Telomerase Reverse Transcriptase Dramatically Improves Ischemic Wound Healing Without Detrimental Immune Response in an Aged Rabbit Model
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55. The telomere story or the triumph of an open-minded research
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56. Microarray analyses in bladder cancer cells: Inhibition of hTERT expression down‐regulates EGFR
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57. Regulation of Telomerase by Human Papillomaviruses
    Denise A. Galloway, Lindy C. Gewin, Hadley E. Myers, W. LUO, Carla Grandori, Rachel A. Katzenellenbogen, James K. McDougall · 2005 · Cold Spring Harbor Symposia on Quantitative Biology
58. Telomerase- and Alternative Telomere Lengthening–Independent Telomere Stabilization in a Metastasis-Derived Human Non–Small Cell Lung Cancer Cell Line: Effect of Ectopic hTERT
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59. Identification of genes involved in the regulation of TERT in hepatocellular carcinoma
    Masataka Amisaki, Hiroyuki Tsuchiya, Tomohiko Sakabe, Yoshiyuki Fujiwara, Goshi Shiota · 2018 · Cancer Science
60. Physiological and pathological significance of human telomerase reverse transcriptase splice variants
    F. Mathias Bollmann · 2013 · Biochimie
61. Tyrphostin AG1478 suppresses proliferation and invasion of human breast cancer cells
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62. ATF5, a possible regulator of osteogenic differentiation in human adipose‐derived stem cells
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63. microRNA-299-3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA
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64. Mechanism of Telomerase Activation by v-Rel and Its Contribution to Transformation
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65. Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells
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66. Telomerase activity in ecological studies: What are its consequences for individual physiology and is there evidence for effects and trade‐offs in wild populations
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67. Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells
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68. Reduced up‐regulation of cytoprotective genes in rat cutaneous tissue during the second cycle of ischemia–reperfusion
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69. Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells
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70. Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer
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71. Telomerase inhibition impairs tumor growth in glioblastoma xenografts
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72. The tamoxifen-induced suppression of telomerase activity in the human hepatoblastoma cell line HepG2: a result of post-translational regulation
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73. Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro
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75. Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes
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76. SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression
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77. Regulation of Telomerase Activity by Interferon Regulatory Factors 4 and 8 in Immune Cells
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79. Establishing tumor cell lines from aggressive telomerase-positive chordomas of the skull base
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80. NFX1-123 is highly expressed in cervical cancer and increases growth and telomerase activity in HPV 16E6 expressing cells
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81. A dual-amplification label-free ratiometric fluorescent sensor for accurate monitoring of telomerase activity based on unique intercalation characteristics of dyes toward different DNA structures
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82. Establishment of human fibroma cell lines from a MEN1 patient by introduction of either hTERT or SV40 early region
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83. Anticancer Therapy Targeting Telomeres and Telomerase
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84. Telomeres, Telomerase, Stress, and Aging
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85. TERT promoter methylation is associated with high expression of TERT and poor prognosis in papillary thyroid cancer
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86. Complicated RNA splicing of chicken telomerase reverse transcriptase revealed by profiling cells both positive and negative for telomerase activity
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89. Human Telomerase Reverse Transcriptase Promotes the Epithelial to Mesenchymal Transition in Lung Cancer Cells by Enhancing c-MET Upregulation
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91. Influence of small interfering RNA corresponding to ets homologous factor on senescence-associated modulation of prostate carcinogenesis
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92. Telomerase as a clinical target: Current strategies and potential applications
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93. Preparation and Characterization of Candidate Reference Materials for Telomerase Assays
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94. Dexmedetomidine reduces enteric glial cell injury induced by intestinal ischaemia‐reperfusion injury through mitochondrial localization of TERT
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95. TERT rs2736100T/G polymorphism upregulates interleukin 6 expression in non-small cell lung cancer especially in adenocarcinoma
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96. Evaluating the Impact of Oxygen Concentration and Plating Density on Human Wharton's Jelly-Derived Mesenchymal Stromal Cells
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97. Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway
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98. Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics
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99. Telomeres and telomerase in normal and malignant B‐cells
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100. A Telomerase Immortalized Human Proximal Tubule Cell Line with a Truncation Mutation (Q4004X) in Polycystin-1
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