Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

Smith, Laura L., Coller, Hilary A., Roberts, James M.·2003·Nature Cell Biology

DOI 10.1038/ncb985

Cited by (435)

Items 301–400 of 435

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Diego Sebastian Ojeda, Juan José López‐Costa, Mariano M. Sede, Ester Marı́a López, María I. Berría, Jorge Fabián Quarleri · 2013 · Journal of Neuroscience Research
Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells
Rosalinda Madonna, Danli Wu, Michael J. Wassler, Raffaele De Caterina, James T. Willerson, Yong‐Jian Geng · 2012 · International Journal of Cardiology
Establishment of Novel Limbus-Derived, Highly Proliferative ABCG2+/ABCB5+ Limbal Epithelial Stem Cell Cultures
Eung Kweon Kim, Ga Hyun Lee, Bo Ram Lee, Yong‐Sun Maeng · 2017 · Stem Cells International
Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer
Linda Kachuri, Jens Helby, Stig E. Bojesen, David C. Christiani, Li Su, Xifeng Wu, Adonina Tardón, Guillermo Fernández‐Tardón, John K. Field, Michael P.A. Davies et al. · 2019 · Cancer Epidemiology Biomarkers & Prevention
Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes
Elizabeth B. Endorf, 青华, Jun Aono, Naoto Terami, Geneviève Doyon, Eric J. Hyzny, Karrie L. Jones, Hannes M. Findeisen, Dennis Bruemmer · 2016 · Arteriosclerosis Thrombosis and Vascular Biology
Loss of the Malignant Phenotype of Human Neuroblastoma Cells by a Catalytically Inactive Dominant-Negative hTERT Mutant
Mona Samy, Charles‐Henry Gattolliat, Frédéric Pendino, Josette Hillion, Éric Nguyen, Sophie Bombard, Sétha Douc‐Rasy, Jean Bénard, Evelyne Ségal-Bendirdjian · 2012 · Molecular Cancer Therapeutics
Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene
Gregory W. Peek, Trygve O. Tollefsbol · 2016 · Experimental Cell Research
Blockade of telomerase reverse transcriptase enhances chemosensitivity in head and neck cancers through inhibition of AKT/ ERK signaling pathways
Tengda Zhao, Fengchun Hu, Xingguang Liu, Qian Tao · 2015 · Oncotarget
Effects of cotransfection of antisense‐EGFR and wild‐type PTEN cDNA on human glioblastoma cells
Xin‐Xia Tian, Yun‐Gang Zhang, Juan Du, Weigang Fang, Ho‐Keung Ng, Jie Zheng · 2006 · Neuropathology
Down-regulation of an inhibitor of cell growth, transmembrane protein 34 (TMEM34), in anaplastic thyroid cancer
Junko Akaishi, Masahiko Onda, Junichi Okamoto, Shizuyo Miyamoto, M Nagahama, Koichi Ito, Akira Yoshida, Kazuo Shimizu · 2006 · Journal of Cancer Research and Clinical Oncology
Shaggy mouse tales
Elizabeth Helen Blackburn · 2005 · Nature
A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes
Emmanuelle Escoffier, Amélie Rezza, Aude Roborel de Climens, Aurélie Belleville, Louis Gazzolo, Éric Gilson, Madeleine Duc Dodon · 2005 · Retrovirology
The acceleration of aging and Alzheimer’s disease through the biological mechanisms behind obesity and type II diabetes
Ian James Martins, Wei Ling Florence Lim, Andrea C. Wilson, Simon Matthew Laws, Ralph Nigel Martins · 2013 · Health
The Regulation of ROS‐ and BECN1‐Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma
Xuelu Ding, Ziyang Nie, Zhaoyuan She, Xue Bai, Qiuhui Yang, Feng Wang, Fei Wang, Xin Geng · 2021 · Oxidative Medicine and Cellular Longevity
Prognostic and Clinicopathological Significance of Telomerase Reverse Transcriptase Upregulation in Oral Cancer: A Systematic Review and Meta-Analysis
Miguel Ángel González‐Moles, Eloísa Moya-González, Alberto García-Ferrera, Paola Nieto-Casado, Pablo Ramos‐García · 2022 · Cancers
Prognostic significance of BRAF V600E and TERT promoter mutations in radioiodine resistance and recurrence of differentiated thyroid cancer
Le Thi Tuyet Nhung, Nghiem Xuan Hoan, Dao Phuong Giang, Dang Trung Dung, Nguyen Thi Phuong, Ngo Thi Minh Hanh, Le Van Khanh, Ngo Thu Hang, Lê Ngọc Hà, Hoang Văn Tong · 2025 · Medicine
Telomerase dynamics in stem cells: Unraveling the molecular nexus of cellular aging and regeneration
Yanhua Jiang, Yongjian Zhou, Yutao Wang, Zhe Li, Ghulam Md Ashraf, Liang Guo · 2025 · Ageing Research Reviews
Telomere - A Complex End of a Chromosome
Marcelo Luis Larramendy · 2016 · InTech eBooks
Involvement of Telomerase Activity Inhibition and Telomere Dysfunction in Silver Nanoparticles Anticancer Effects
Biao Chen, Yajun Zhang, Yaning Yang, Shaopeng Chen, An Xu, Lijun Wu, Shengmin Xu · 2018 · Nanomedicine
Telomere dysfunction and telomerase activation in cancer – a pathological paradox?
Olga Calcagnile, David Gisselsson · 2007 · Cytogenetic and Genome Research
Activation of telomerase and cyclooxygenase‐2 in PDGF and FGF inhibition of C 2 ‐ceramide‐induced apoptosis
Chih‐Chiang Chien, Shing‐Chuan Shen, Liang‐Yo Yang, Chin-Yen Wu, Jiun‐Shiang Liau, Yen‐Chou Chen · 2008 · Journal of Cellular Physiology
Direct activation of telomerase by GH via phosphatidylinositol 3′-kinase
L Gómez-García, F M Sánchez, María Teresa Vallejo‐Cremades, Ignacio Álvarez Gómez de Segura, E. de Miguel del Campo · 2005 · Journal of Endocrinology
Global expression profile of telomerase-associated genes in HeLa cells
Akhil Varshney, Suresh Kumar Ramakrishnan, Amod Sharma, Baby Santosh, Jyoti Bala, Pramod Kumar Yadava, Rishi Kumar Jaiswal · 2014 · Gene
Saccharomyces cerevisiae as a model for the study of extranuclear functions of mammalian telomerase
Lucia Šimoničová, Henrieta Dudekova, Jaroslav Ferenc, Katarína Procházková, Martina Neboháčová, Roman Dušinský, Jozef Nosek, Ľubomír Tomáška · 2015 · Current Genetics
Mechanism of induction of apoptosis by siRNA targeting hTERT in HeLa cells
Jian Wang, Chang-shan Ren · 2008 · Chinese Journal of Cancer Research
Real-time telomerase assay of less-invasively collected esophageal cell samples
Brenna M. McGruder, Donald H. Atha, Wendy Wang, Konrad E. Huppi, Wen-Qiang Wei, Christian C. Abnet, You‐Lin Qiao, Sanford M. Dawsey, Philip R. Taylor, John P. Jakupciak · 2006 · Cancer Letters
A putative telomerase activator has tissue‐specific effects on telomere length in a developing songbird
Sarah E. Wolf, Keegan R. Stansberry, Kristen R. Content, Kimberly A. Rosvall · 2021 · Journal of Avian Biology
Differential Induction in Telomerase Activity among Bladder Cancer Patients and Controls on γ-Radiation
Jinliang Xing, Yong Lian Zhu, Hua Zhao, Hushan Yang, Meng Chen, Margaret R. Spitz, Xifeng Wu · 2007 · Cancer Epidemiology Biomarkers & Prevention
Screening and Identification of Molecular Targets Involved in Preventing Gastric Precancerous Lesions in Chronic Atrophic Gastritis by Qilianshupi Decoction
Yameng Zhang, Chao Li, Shanmei Sun, Zhiqun Cao, Jian Chen, Hongjie Xiang, Lucheng Song · 2019 · Evidence-based Complementary and Alternative Medicine
No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells
Natalie Erdmann, Lea A. Harrington · 2008 · DNA repair
Effect of TERT and ATM on gene expression profiles in human fibroblasts
Ágnes Baross, Mike Schertzer, Scott Zuyderduyn, Steven J.M. Jones, Marco A. Marra, Peter M. Lansdorp · 2004 · Genes Chromosomes and Cancer
Telomerase inhibitors induce mitochondrial oxidation and DNA damage-dependent cell death rescued by Bcl-2/Bcl-xL
Aparna Geetha Jayaprasad, Aneesh Chandrasekharan, Srinivas Jyothi, S.M. John Sam, Thankayyan Retnabai Santhoshkumar, M. Radhakrishna Pillai · 2024 · International Journal of Biological Macromolecules
Irradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population
Xianli He, Qing Qiao, Naijian Ge, Nan Jing, Shuqun Shen, Zizhong Wang, Yefa Yang, Guoqiang Bao · 2010 · BMC Cancer
Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice
Mengying Liu · 2012 · Journal of Biomedical Research
Establishment of immortalized Schwann cells derived from rat embryo dorsal root ganglia
Huajun Jiang, Wei Qü, FENG HAN, DAZHUANG LIU, Weiguo Zhang · 2012 · International Journal of Molecular Medicine
Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation
Delphine Tamara Marie-Egyptienne, Marie Eve Brault, Shusen Zhu, Chantal Autexier · 2007 · Experimental Cell Research
Gene expression responses in vivo by human telomerase reverse transcriptase (hTERT)-targeting trans-splicing ribozyme
Min-Sun Song, Jin‐Sook Jeong, Kyung-Sook Cho, Seong‐Wook Lee · 2007 · Experimental & Molecular Medicine
TERT over-expression affects the growth of myocardial tissue derived from mouse embryonic stem cells
Sebastián Brandt · 2009 · Differentiation
Revisiting the hallmarks of cancer: A new look at long noncoding RNAs in breast cancer
Pablo Igor Ribeiro Franco, José Rodrigues do Carmo Neto, Liliana Borges de Menezes, Juliana Reis Machado, Marina Pacheco Miguel · 2023 · Pathology - Research and Practice
Télomère et cancer : quoi de plus à la fin ?
Michèle Brunori, Éric Gilson · 2005 · médecine/sciences
Establishment and Characterization of Three Immortal Bovine Muscular Epithelial Cell Lines
Xun Jin, Joong-Seob Lee, Sungwook Kwak, Soo-Yeon Lee, Ji-Eun Jung, Tae-Kyung Kim, Chenxiong Xu, Zhong-Shan Hong, Zhehu Li, Sun-Myung Kim et al. · 2006 · Molecules and Cells
Andrographis paniculata extract as an immunity modulator against cancer via telomerase inhibition
Alireza Valdiani, Hamideh Ofoghi, Mahboobeh Akbarizare, Daryush Talei · 2022 · 3 Biotech
Association between hTERT rs2736100 polymorphism and sensitivity to anti-cancer agents
Julie J. Kim, Yava Jones‐Hall, Rongrong Wei, Jamie L. Myers, Yuan Qi, Gregory T. Knipp, Wanqing Liu · 2013 · Frontiers in Genetics
Intracellular efficacy of tumor‐targeting group I intron‐based trans‐splicing ribozyme
Byung Su Kwon, Jin Sook Jeong, You-Sub Won, Chang Ho Lee, Kyung‐Sik Yoon, Min Hyung Jung, In‐Hoo Kim, Seong‐Wook Lee · 2011 · The Journal of Gene Medicine
Platelet-Derived Growth Factor Receptor-Alpha Expressing Cardiac Progenitor Cells Can Be Derived from Previously Cryopreserved Human Heart Samples
Thi Yen Loan Le, Hilda A. Pickett, Cristobal G. dos Remedios, Pasquale Barbaro, Eddy Kizana, James J.H. Chong · 2017 · Stem Cells and Development
Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets
Mathushan Subasri, Parisa Shooshtari, Andrew John Watson, Dean Harvey Betts · 2021 · Cancers
Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation
Nissim Arish, Pazit Y. Cohen, Regina Golan‐Gerstl, Zvi Gregorio Fridlender, Mark Richter-Dayan, Philip Zisman, Raphael Breuer, Shulamit B. Wallach‐Dayan · 2015 · PLoS ONE
Recombinant adenovirus‐mediated human telomerase reverse transcriptase gene can stimulate cell proliferation and maintain primitive characteristics in bovine mammary gland epithelial cells
Xiaoying He, Yue‐Mao Zheng, Jie Lan, Yue‐Hong Wu, Jing Yan, Xiaoning He, Tuo Zhang, Yulong He, Yanling Zheng, Yong Zhang · 2011 · Development Growth & Differentiation
Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells
Suresh Kumar Ramakrishnan, Akhil Varshney, Amod Sharma, Bhudev Chandra Das, Pramod Kumar Yadava · 2014 · Tumor Biology
Amadori‐glycated phosphatidylethanolamine up‐regulates telomerase activity in PANC‐1 human pancreatic carcinoma cells
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The Landscape of Telomere Length and Telomerase in Human Embryos at Blastocyst Stage
Fang Wang, David H. McCulloh, Kasey Chan, Ashley M. Wiltshire, Caroline McCaffrey, JAMIE A. GRIFO, David Lawrence Keefe · 2023 · Genes
Télomères : un Nobel pour le début de la fin
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Paola Rebuzzini, Paola Martinelli, Marı́a A. Blasco, Elena Giulotto, Chiara Mondello · 2006 · Carcinogenesis
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Beatriz Llamusí, Mari‐Paz Rubio, Almudena Ramón‐Cueto · 2010 · Experimental Neurology
TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program
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Victor J. Passanisi, Sabrina L. Spencer · 2026 · iScience
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Fortunato Scalera, Stefanie M. Bode‐Böger · 2010 · Elsevier eBooks
Cancer Cell Targeting with Mouse TERT-Specific Group I Intron of Tetrahymena thermophila
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The Relationship between Telomerase Activity and Clinicopathological Parameters in Colorectal Cancer: A Meta-Analysis
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Maria Laura Falchetti, Roberto Pallini M. D, Andrea Levi · 2004 · American Journal of Cancer
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Sinusoidal swinging dynamics of the telomere repair and cell growth activation functions of telomerase in rat liver cancer cells
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Telomerase and telomere dysregulation in Polychlorinated Biphenyl (PCB) exposed human skin keratinocytes
Senthilkumar P. Kuppusamy · 2012
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PIWI Interacting RNA-651 Inhibition Transforms the Genetic Features of MCF-7 Breast Cancer Cells
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Synergistic Activation of Extracellular Signal-Regulated Kinase in Human Dermal Fibroblasts by Human Telomerase Reverse Transcriptase and Transforming Growth Factor-β1
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Virginia Boccardi, Clara Tinarelli, Patrizia Mecocci · 2018 · Elsevier eBooks
A novel telomerase activity and microRNA-21 upregulation identified in a family with palmoplantar keratoderma
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Johanna Mancini, Chantal Autexier · 2012 · Wiley eBooks
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Telomeres, Telomerase, Chromosome Stability, and Prostate Cancer
Alan Keith Meeker · 2007 · Humana Press eBooks
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MP Mongiardi · 2009 · Cineca Institutional Research Information System (Tor Vergata University)
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