The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK

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27. Molecular dynamics study of TMPA mediated dissociation of Nur77-LKB1 complex
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39. Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)
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41. SAR study of oxidative DIMs analogs targeting the Nur77-mediated apoptotic pathway of cancer cells
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42. Oxidized analogs of Di(1H-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity
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43. Disruption of heme homeostasis by nuclear receptor Nur77 induces pyroptosis through granzyme B-dependent GSDMC cleavage
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44. Perfluorooctane Sulfonate (PFOS) and Related Compounds Induce Nuclear Receptor 4A1 (NR4A1)-Dependent Carcinogenesis
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45. Identification of novel anti-inflammatory Nur77 modulators by virtual screening
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46. Identification of Indoquinazoline Derivatives as Novel NR4A1 Agonists by Suppressing Adipocyte Lipogenesis for Treatment of Obesity
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47. Mechanisms of orphan nuclear receptor Nur77 in liver health, disease, and therapeutic potential: narrative review
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48. Structure-Based Design and Optimization of Bi-Aryl Amide Derivatives as Nur77 Ligands for Nur77-Bcl-2-Dependent Apoptotic Cancer Therapy
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49. NR4A1 deficiency promotes carotid plaque vulnerability by activating integrated stress response via targeting Bcat1
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53. Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77
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55. No Tumor Suppressor Role for LKB1 in Prostate Cancer
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56. The Roles of Nuclear Receptor NR4A1 in Cancer Cell Proliferation and Skeletal Muscle Differentiation
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64. Negative Feedback by NUR77/ Nr4a1 Restrains B Cell Clonal Dominance During Early T-Dependent Immune Responses
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65. Molecular characterisation of DHR38: the Drosophila ortholog of NR4A family of nuclear receptors
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69. The regulation of NR4A1 on glucolipid metabolism
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74. Additional file 1 of PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation
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75. Design, synthesis and evaluation of Nur77 modulators for lysosome dysfunction–driven therapy of gastric cancer
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76. Cellular factors controlling human L1 retrotransposition
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77. A licorice-derived compound 2,3β-dihydroxy-11-oxo-olean-12-en-30-oic acid to treat obesity and type 2 diabetes in mice
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79. A first-in-class methuosis inducer targeting Nur77/LYSET axis for the treatment of non-small cell lung cancer, irrespective of cisplatin resistance
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80. BindingDB Entry 50009028: SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.
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81. BindingDB Entry 50013822: Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway.
    BindingDB · 2022 · UC San Diego
82. BindingDB Entry 50014784: Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.
    BindingDB · 2023 · UC San Diego
83. Data for "Bile acids target an exposed cavity in the glucocorticoid receptor modulating receptor self-assembly, chromatin binding and transcriptional activity"
    Alba Jiménez‐Panizo, Thomas A. Johnson, Kaustubh Wagh, Andrea Alegre‐Martí, Inés Montoya-Novoa, Agustina L. Lafuente, Ulrich Eckhard, Luis Angel Rodríguez‐Lumbreras, Le Hoang, Martín Stortz et al. · 2025 · Zenodo (CERN European Organization for Nuclear Research)
84. BindingDB Entry 50018264: Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation.
    BindingDB · 2024 · UC San Diego
85. BindingDB Entry 50016957: Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration.
    BindingDB · 2023 · UC San Diego
86. BindingDB Entry 50019759: Discovery of 5-(Pyrimidin-2-ylamino)-1
    BindingDB · 2024 · UC San Diego