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Transforming Growth Factor β /NR4A1-Inducible Breast Cancer Cell Migration and Epithelial-to-Mesenchymal Transition Is p38 α (Mitogen-Activated Protein Kinase 14) Dependent

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SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway

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Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration

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Therapeutic potential of NR4A1 in cancer: Focus on metabolism

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Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity

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Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats

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PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1

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Orphan nuclear receptors as drug targets for the treatment of prostate and breast cancers

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Energy sensing and cancer: LKB1 function and lessons learnt from Peutz–Jeghers syndrome

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Orphan nuclear receptor 4A1 (NR4A1) and novel ligands

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Flavonoids Quercetin and Kaempferol Are NR4A1 Antagonists and Suppress Endometriosis in Female Mice

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NR4A family members regulate T cell tolerance to preserve immune homeostasis and suppress autoimmunity

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The Interplay of AMP-Activated Protein Kinase and Androgen Receptor in Prostate Cancer Cells

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PKA Activates AMPK Through LKB1 Signaling in Follicular Thyroid Cancer

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A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome

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BI1071, a Novel Nur77 Modulator, Induces Apoptosis of Cancer Cells by Activating the Nur77-Bcl-2 Apoptotic Pathway

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Dual Roles of Orphan Nuclear Receptor TR3/Nur77/NGFI-B in Mediating Cell Survival and Apoptosis

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Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity

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mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1

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Nur77 deficiency leads to systemic inflammation in elderly mice

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Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function

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Dual targeting of Nur77 and AMPKα by isoalantolactone inhibits adipogenesis in vitro and decreases body fat mass in vivo

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Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements

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Targeting Orphan Nuclear Receptors NR4As for Energy Homeostasis and Diabetes

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PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1

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The E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α

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NR4A nuclear receptors in T and B lymphocytes: Gatekeepers of immune tolerance*

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Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)

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Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS)

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Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells

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LKB1 biology: assessing the therapeutic relevancy of LKB1 inhibitors

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NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth

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Resveratrol Binds Nuclear Receptor 4A1 (NR4A1) and Acts as an NR4A1 Antagonist in Lung Cancer Cells

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The nuclear orphan receptor NR4A1 regulates β1‐integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists

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New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy

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Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

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Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

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Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses

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LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer

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The Prognostic Value of Decreased LKB1 in Solid Tumors: A Meta-Analysis

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Time-of-day defines NAD+ efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice

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RORα suppresses proliferation of vascular smooth muscle cells through activation of AMP-activated protein kinase

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Exploring the mechanism of metformin action in Alzheimer’s disease and type 2 diabetes based on network pharmacology, molecular docking, and molecular dynamic simulation

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Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates

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Discovery of 5-(Pyrimidin-2-ylamino)-1H-indole-2-carboxamide Derivatives as Nur77 Modulators with Selective and Potent Activity Against Triple-Negative Breast Cancer

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The orphan nuclear receptor NR4A1 promotes FcεRI‐stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis

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Repurposing Metformin for Vascular Disease

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The cellular and molecular targets of natural products against metabolic disorders: a translational approach to reach the bedside

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Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity

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Nur77 Is Upregulated in B-1a Cells by Chronic Self-Antigen Stimulation and Limits Generation of Natural IgM Plasma Cells

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Pro-angiogenic Ginsenosides F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1

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Creation of an Anti-Inflammatory, Leptin-Dependent Anti-Obesity Celastrol Mimic with Better Druggability

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Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1)

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Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα

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NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β‐cells for protection

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Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

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Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway

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The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

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