Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J. +18 more·2016·Nature Communications
Cited by (1,000)
Items 801–900 of 1,000
- Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/− Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic TargetsTuba Nur Gide, Inês Pires da Silva, Camelia Y. J. Quek, Peter M. Ferguson, Marcel Batten, Ping Shang, Tasnia Ahmed, Alexander Maxwell Menzies, Matteo Salvatore Carlino, Robyn P.M. Saw et al. · 2021 · Cancers
- Glioblastoma: Pitfalls and Opportunities of Immunotherapeutic CombinationsMarcin Niedbała, Katarzyna Malarz, Gitanjali Sharma, Gabriela Krämer-Marek, Wojciech Kaspera · 2022 · OncoTargets and Therapy
- Immunotherapy for Head and Neck CancerSumita Trivedi, Lova Sun, Charu Aggarwal · 2021 · Hematology/Oncology Clinics of North America
- The abnormal expression of Tim-3 is involved in the regulation of myeloid-derived suppressor cells and its correlation with preeclampsiaShuai Dong, Neelam Kumari Shah, Jin He, Shumei Han, Min Xie, Ying Wang, Tingting Cheng, Zitao Liu, Chang Shu · 2021 · Placenta
- Expression, prognostic significance and therapeutic implications of PD‐L1 in gliomasGayaththri Vimalathas, Bjarne Winther Kristensen · 2021 · Neuropathology and Applied Neurobiology
- Clinical Efficacy and Future Prospects of Immunotherapy in Lung CancerTomonari Kinoshita, Hideki Terai, Tomonori Yaguchi · 2021 · Life
- Future Prospects of Immunotherapy in Non-Small-Cell Lung Cancer Patients: Is There Hope in Other Immune Checkpoints Targeting Molecules?Natalia Krzyżanowska, Kamila Wojas‐Krawczyk, Janusz Milanowski, Paweł Adam Krawczyk · 2022 · International Journal of Molecular Sciences
- Synthetic and Biodegradable Molybdenum(IV) Diselenide Triggers the Cascade Photo‐ and Immunotherapy of TumorJiulong Zhao, Yao Zhang, Jing Zhang, Hang Wu, Jinfeng Li, Yizhou Zhao, Liying Zhang, Duowu Zou, Zhao‐Shen Li, Shige Wang · 2022 · Advanced Healthcare Materials
- Primary and Acquired Resistance against Immune Check Inhibitors in Non-Small Cell Lung CancerQinying Sun, Xiangzhen Wei, Zhonglin Wang, Yan Yu Zhu, Weiying Zhao, Yuchao Dong · 2022 · Cancers
- Prevalence and prognostic significance of PD-L1, TIM-3 and B7-H3 expression in endometrial serous carcinomaHao Chen, Kyle H. Molberg, Kelley S. Carrick, Shuang Niu, Glorimar Rivera-Colón, Katja Gwin, Cheryl M. Lewis, Wenxin Zheng, Diego H. Castrillón, Elena Lucas · 2022 · Modern Pathology
- The Tumor Immune Microenvironment in Primary CNS Neoplasms: A Review of Current Knowledge and Therapeutic ApproachesAnita L. Kalluri, Pavan P. Shah, Michael K. Lim · 2023 · International Journal of Molecular Sciences
- Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCCJacob Gadwa, Maria Amann, Thomas E. Bickett, Michael W. Knitz, Laurel B. Darragh, Miles Piper, Benjamin Van Court, Sanjana Bukkapatnam, Tiffany Pham, Xiao‐Jing Wang et al. · 2023 · Cell Reports Medicine
- Interplay between inflammasomes and PD-1/PD-L1 and their implications in cancer immunotherapyZhongyu Jiao, Jun Zhang · 2023 · Carcinogenesis
- Alternative immune checkpoints in immunoregulatory profile of cancer stem cellsKeywan Mortezaee, Jamal Majidpoor · 2023 · Heliyon
- Sabatolimab in combination with spartalizumab in patients with non-small cell lung cancer or melanoma who received prior treatment with anti-PD-1/PD-L1 therapy: a phase 2 multicentre studyChia‐Chi Lin, Giuseppe Curigliano, Armando Santoro, Dong‐Wan Kim, David Wai-Meng Tai, Frank Stephen Hodi, Sofie Wilgenhof, Toshihiko Doi, Catherine A. Sabatos-Peyton, Sebastian Szpakowski et al. · 2024 · BMJ Open
- In situ vaccination with biocompatibility controllable immuno-sensitizer inducing antitumor immunityHeejun Shin, Kun Na · 2019 · Biomaterials
- Immunological and clinical implications of immune checkpoint blockade in human cancerHyung‐Don Kim, Su‐Hyung Park · 2019 · Archives of Pharmacal Research
- My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to combat cancerAlexander Levitzki, Shoshana Klein · 2019 · Proceedings of the National Academy of Sciences
- Immunological Targets for Immunotherapy: Inhibitory T Cell ReceptorsDiwakar Davar, Hassane M. Zarour · 2019 · Methods in molecular biology
- Melanoma immunotherapy: strategies to overcome pharmacological resistanceClaudia Trojaniello, Maria Grazia Vitale, Luigi Scarpato, Assunta Esposito, Paolo A. Ascierto · 2020 · Expert Review of Anticancer Therapy
- Evolving Role of Daratumumab: From Backbencher to Frontline AgentAnkur Jain, Karthik Ramasamy · 2020 · Clinical Lymphoma Myeloma & Leukemia
- Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapyLucas C. Adam, Junaid Y. Raja, Johannes Maximilian Ludwig, Adebowale Adeniran, Scott N. Gettinger, Hyun S. Kim · 2018 · Journal for ImmunoTherapy of Cancer
- Tumour Regression via Integrative Regulation of Neurological, Inflammatory, and Hypoxic Tumour MicroenvironmentChang Hoon Lee, Jungsook Cho, Kyeong Lee · 2019 · Biomolecules & Therapeutics
- Role of Biofunctionalized Nanoparticles in Digestive Cancer Vaccine DevelopmentRazvan Septimiu Zdrehus, Cristian Delcea, Lucian Constantin MOCAN · 2024 · Pharmaceutics
- Single-cell multi-omics analysis reveals candidate therapeutic drugs and key transcription factor specifically for the mesenchymal subtype of glioblastomaYufan Yang, Ziyuan Liu, Yerong Wei, Shuai He, Ancheng Gu, Zhiyong Li, Jianlong Li, Zhongyuan Xu, Bohong Cen · 2024 · Cell & Bioscience
- Immune Modulation and Immunotherapy in Solid Tumors: Mechanisms of Resistance and Potential Therapeutic StrategiesSuman Giri, Gopal Lamichhane, Jitendra Pandey, Ramesh Khadayat, Sindhu KC, Hari Prasad Devkota, Dipendra Khadka · 2025 · International Journal of Molecular Sciences
- Combinational therapeutic strategies to overcome resistance to immune checkpoint inhibitorsBesan H. Al-Saafeen, Bassam R. Ali, Eyad Elkord · 2025 · Frontiers in Immunology
- Targeting TIM-3 in solid tumors: innovations in the preclinical and translational realm and therapeutic potentialReem Saleh, Salman M. Toor, Eyad Elkord · 2020 · Expert Opinion on Therapeutic Targets
- 5‐Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death‐ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma modelXin Hu, Weitao Que, Hiroshi Hirano, Zhidan Wang, Naoko Nozawa, Takuya Ishii, Masahiro Ishizuka, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima et al. · 2021 · Cancer Science
- TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 ImmunotherapyKirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Quentin Lecocq, Eva Reijmen et al. · 2022 · Frontiers in Immunology
- Identification of a novel small-molecule inhibitor targeting TIM-3 for cancer immunotherapyMenghan Wu, Aijun Wu, Xiangrui Zhang, Yang Li, Beibei Li, Shengzhe Jin, Qingyu Dong, Xiaoshuang Niu, Lihan Zhang, Xiaowen Zhou et al. · 2023 · Biochemical Pharmacology
- Analysis of Immune Resistance Mechanisms in TNBC: Dual Effects Inside and Outside the TumorJian Xu, Gan Chen, Sheng Yu, Senbang Yao, Wen Li, Huaidong Cheng · 2023 · Clinical Breast Cancer
- Strengthening the Combinational Immunotherapy from Modulating the Tumor Inflammatory Environment via Hypoxia‐Responsive NanogelsWenhe Luo, Yanqiao Zeng, Qingle Song, Yu Wang, Feng Yuan, Qi Li, Yingnan Liu, Su Li, Nahar Jannatun, Guofang Zhang et al. · 2023 · Advanced Healthcare Materials
- Research progress and challenges of the PD-1/PD-L1 axis in gliomasDong Jiacheng, Jiayue Cui, Guo Ying, Wang Shaohua, Liu Wenhui, Xinyu Hong · 2024 · Cell & Bioscience
- Glioblastoma and Immune Checkpoint Inhibitors: A Glance at Available Treatment Options and Future DirectionsSilvia Mara Baez Rodriguez, Ligia Gabriela Tătăranu, Amira Kamel, Șerban Turliuc, Radu Eugen Rizea, Anica Dricu · 2024 · International Journal of Molecular Sciences
- Cancer Immunotherapy Getting Brainy: Visualizing the Distinctive CNS Metastatic Niche to Illuminate Therapeutic ResistanceMark Owyong, Niloufar Hosseini-Nassab, Gizem Efe, Alexander T. Honkala, Renske J.E. van den Bijgaart, Vicki Plaks, Bryan Ronain Smith · 2017 · Drug Resistance Updates
- Liquid biopsy for lung cancer immunotherapy (Review)Liangliang Cai, Jie Wang · 2019 · Oncology Letters
- Research progress and clinical application of predictive biomarker for immune checkpoint inhibitorsKe Ma, Qingqing Jin, Miao Wang, Xin Li, Yuyang Zhang · 2019 · Expert Review of Molecular Diagnostics
- Biological regulation of diacylglycerol kinases in normal and neoplastic tissues: New opportunities for cancer immunotherapyJavier Arranz‐Nicolás, Isabel Mérida · 2019 · Advances in Biological Regulation
- Acquired Resistance to Immune Checkpoint Blockade TherapiesXianda Zhao, Dechen Wangmo, Matthew J. Robertson, Subbaya Subramanian · 2020 · Cancers
- Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma PatientsChaojun Liu, Zhen Zhang, Ping Yü, Guohui Qin, Kai Zhang, Nomathamsanqa Resegofetse Maimela, Lan Ji Huang, Shengli Yang, Yi Zhang · 2020 · Cancer Management and Research
- Exploration of Feasible Immune Biomarkers for Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinoma Treatment in Real World Clinical PracticeHui‐Ching Wang, Tsung‐Jang Yeh, Leong‐Perng Chan, Chin‐Mu Hsu, Shih‐Feng Cho · 2020 · International Journal of Molecular Sciences
- Front Line Applications and Future Directions of Immunotherapy in Small-Cell Lung CancerSelina K. Wong, Wade Thomas Iams · 2021 · Cancers
- Tumor-associated antigen–specific T cells with nivolumab are safe and persist in vivo in relapsed/refractory Hodgkin lymphomaHema Dave, Madeline Terpilowski, Mimi Mai, Keri Toner, Melanie Grant, Maja Stanojevic, Christopher A. Lazarski, Abeer Shibli, Stephanie A. Bien, Philip Y Maglo et al. · 2021 · Blood Advances
- Role of Ezrin/Radixin/Moesin in the Surface Localization of Programmed Cell Death Ligand-1 in Human Colon Adenocarcinoma LS180 CellsTakuro Kobori, Chihiro Tanaka, Mayuka Tameishi, Yoko Urashima, Takuya Ito, Tokio Obata · 2021 · Pharmaceuticals
- The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune SystemEdmund K. Moon, Corey Jay Langer, Steven Μ. Albelda · 2017 · Annals of the American Thoracic Society
- Immunotherapy resistance: the answers lie ahead – not in front – of usMiles Cameron Andrews, Jennifer Ann Wargo · 2017 · Journal for ImmunoTherapy of Cancer
- Second-Line Treatment after Failure of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma: Tyrosine Kinase Inhibitor, Retrial of Immunotherapy, or Locoregional Therapy?Sang Youn Hwang, Sangjune Laurence Lee, Hongqun Liu, Samuel S. Lee · 2023 · Liver Cancer
- Solid tumour-induced systemic immunosuppression involves dichotomous myeloid–B cell interactionsXiaoxin Hao, Yichao Shen, Jun Liu, Angela Alexander, Ling Wu, Zhan Xu, Liqun Yu, Yang Gao, Fengshuo Liu, Hilda L. Chan et al. · 2024 · Nature Cell Biology
- The response to anti–PD-1 and anti–LAG-3 checkpoint blockade is associated with regulatory T cell reprogrammingAnnah S. Rolig, Xiyu Peng, Elizabeth R. Sturgill, Nisha Holay, Melissa J. Kasiewicz, Courtney Mick, Grace Helen McGee, William Miller, Yoshinobu Koguchi, Johanna Kaufmann et al. · 2025 · Science Translational Medicine
- Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironmentYasuharu Haku, Koji Kitaoka, Koki Ichimaru, T Hirano, Jun Wang, Kazuhiro Sonomura, Asuka Maruo, Shuhei Hirose, Yu Wang, Katsuhiro Ito et al. · 2026 · Nature Immunology
- Melanoma: Prognostic Factors and Factors Predictive of Response to TherapyMartina Strudel, Lucia Festino, Vito Vanella, Massimiliano Beretta, Francesco Maria Marincola, Paolo A. Ascierto · 2019 · Current Medicinal Chemistry
- The biologically functional identification of a novel TIM3-binding peptide P26 in vitro and in vivoTangwu Zhong, Chuanke Zhao, Shuntao Wang, Deshuang Tao, Shuxia Ma, Chengchao Shou · 2020 · Cancer Chemotherapy and Pharmacology
- Overcoming Resistance to Immunotherapy in Advanced Cutaneous Squamous Cell CarcinomaNatalia García‐Sancha, Roberto Corchado‐Cobos, Lorena Bellido-Hernández, Concepción Román‐Curto, Esther Cardeñoso Álvarez, Jesús Pérez‐Losada, Alberto Órfão, Javier Cañueto · 2021 · Cancers
- Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy?Yuanwei Shi, Danting Tang, Xiaoqi Li, Xiaoli Xie, Yufu Ye, Lijuan Wang · 2022 · Frontiers in Oncology
- Development of Inhibitors Targeting the V-Domain Ig Suppressor of T Cell Activation Signal PathwayShuai Zheng, Kuojun Zhang, Xiangyu Zhang, Yibei Xiao, Tianyu Wang, Sheng Jiang · 2022 · Journal of Medicinal Chemistry
- Mechanisms of primary and acquired resistance to immune checkpoint inhibitors in advanced non–small cell lung cancer: A multiplex immunohistochemistry–based single-cell analysisKohsuke Isomoto, Koji Haratani, Takahiro Tsujikawa, Yusuke Makutani, Hisato Kawakami, Masayuki Takeda, Kimio Yonesaka, Kaoru Tanaka, Tsutomu Iwasa, Hidetoshi Hayashi et al. · 2022 · Lung Cancer
- Tackling of Immunorefractory Tumors by Targeting Alternative Immune CheckpointsDharmindra Dulal, Andrew R. Boring, David Terrero, Tiffany L. Johnson, Amit Kumar Tiwari, Dayanidhi Raman · 2023 · Cancers
- Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGITKatty Zeven, Timo W.M. De Groof, Hannelore Ceuppens, Robin Maximilian Awad, Thomas Ertveldt, Wout de Mey, Fien Meeus, Geert Raes, Karine Breckpot, Nick Devoogdt · 2023 · Frontiers in Immunology
- The role of programmed death receptor (PD‐)1/PD‐ligand (L)1 in periodontitis and cancerSabine Elisabeth. Groeger, Joerg Meyle · 2024 · Periodontology 2000
- Immune-inflammatory modulation by natural products derived from edible and medicinal herbs used in Chinese classical prescriptionsQianming Kang, Luying He, Yang Zhang, Zhangfeng Zhong, Wen Tan · 2024 · Phytomedicine
- Transient immunological and clinical effectiveness of treating mice bearing premalignant oral lesions with PD‐1 antibodiesCorinne A. Levingston, M. Young · 2017 · International Journal of Cancer
- Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor TherapyShixue Chen, Lingling Li, Fan Zhang, Yu Wang, Yi Hu, Lei Zhao · 2019 · Journal of Immunology Research
- Overcoming malignant cell-based mechanisms of resistance to immune checkpoint blockade antibodiesReham Ajina, David J. Zahavi, Yongwei Zhang, Louis M. Weiner · 2019 · Seminars in Cancer Biology
- Concurrent Injection of Unlabeled Antibodies Allows Positron Emission Tomography Imaging of Programmed Cell Death Ligand 1 Expression in an Orthotopic Pancreatic Tumor ModelJun Zhao, Xiaoxia Wen, Tingting Li, Sixiang Shi, Chiyi Xiong, Yanru Wang, Chun Li · 2020 · ACS Omega
- Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytesJavier Arranz‐Nicolás, Miguel Martin-Salgado, Cristina Rodríguez‐Rodríguez, Rosa Liébana, María C. Moreno-Ortíz, Judith Maria Leitner, Peter Steinberger, Antonia Ávila‐Flores, Isabel Mérida · 2020 · Journal for ImmunoTherapy of Cancer
- Complex Interaction Among Immune, Inflammatory, and Carcinogenic Mechanisms in the Head and Neck Squamous Cell CarcinomaAna Căruntu, Cristian Scheau, Mircea Ştefan Tampa, Simona Roxana Georgescu, Constantin Căruntu, Cristiana Tănase · 2021 · Advances in experimental medicine and biology
- Clinical Perspectives to Overcome Acquired Resistance to Anti–Programmed Death-1 and Anti–Programmed Death Ligand-1 Therapy in Non-Small Cell Lung CancerYong Jun Lee, Jii Bum Lee, Sang‐Jun Ha, Hye Ryun Kim · 2021 · Molecules and Cells
- The Balance between Differentiation and Terminal Differentiation Maintains Oral Epithelial HomeostasisYuchen Bai, Jarryd Boath, Gabrielle R. White, U. G. I. U. Kariyawasam, Camile Selim Farah, Charbel Darido · 2021 · Cancers
- CD73/Adenosine Pathway Involvement in the Interaction of Non-Small Cell Lung Cancer Stem Cells and Bone Cells in the Pre-Metastatic NicheGiulia Bertolini, Mara Compagno, Dimas Carolina Belisario, Cristiano Bracci, Tullio Genova, Federico Davide Mussano, Massimo Vitale, Alberto L. Horenstein, Fabio Malavasi, Riccardo Ferracini et al. · 2022 · International Journal of Molecular Sciences
- Lack of MHC class II molecules favors CD8+T-cell infiltration into tumors associated with an increased control of tumor growthNada Chaoul, Alexandre Tang, Belinda Desrues, Marine Oberkampf, Catherine Fayolle, Daniel Ladant, Alexander Sainz‐Perez, Claude Leclerc · 2017 · OncoImmunology
- The Immune Landscape of Non–Small-Cell Lung Cancer: Utility of Cytologic and Histologic Samples Obtained through Minimally Invasive Pulmonary ProceduresJason Beattie, Lonny B. Yarmus, Momen M. Wahidi, M. Patricia Rivera, Christopher R. Gilbert, Fabien Maldonado, Kasia Czarnecka, Angela Christine Argento, Alexander Junxiang Chen, Felix J.F. Herth et al. · 2018 · American Journal of Respiratory and Critical Care Medicine
- Cryoablation and post-progression immune checkpoint inhibition in metastatic melanoma: a phase II trialMeghan J. Mooradian, Florian Johannes Fintelmann, Thomas James LaSalle, Judit Simon, Alexander Graur, Alona Muzikansky, Mari A. Mino-Kenudson, Sophia Z. Shalhout, Howard L. Kaufman, Russell William Jenkins et al. · 2024 · Nature Communications
- Deciphering LAG-3: unveiling molecular mechanisms and clinical advancementsAlejandra Martínez‐Pérez, Rocío Granda‐Díaz, Candelaria Aguilar-García, Christian Sordo‐Bahamonde, Segundo R. Gonzalez · 2024 · Biomarker Research
- Multi-omics dissection of tumor microenvironment-mediated drug resistance: mechanisms and therapeutic reprogrammingFanghua Chen, Yu Fu, Gaigai Bai, Junjun Qiu, Keqin Hua · 2025 · Frontiers in Pharmacology
- Addressing clinical needs in NSCLC immunotherapy: Mechanisms of resistance and promising combination strategiesKai Kang, Shanghai Liu, Zhuoran Yao, Jianxin Xue, You Lu · 2025 · Cell Reports Medicine
- Downregulation of Interferon-γ Receptor Expression Endows Resistance to Anti–Programmed Death Protein 1 Therapy in Colorectal CancerChunxiao Lv, Dongfen Yuan, Yanguang Cao · 2020 · Journal of Pharmacology and Experimental Therapeutics
- Evolution of Lung Cancer in the Context of ImmunotherapySheng Yu, Ruilin Wang, Hong Tang, Lili Wang, Zhe Zhang, Sen Yang, Shuyue Jiao, Xuan Wu, Shuai Wang, Mingyue Wang et al. · 2020 · Clinical Medicine Insights Oncology
- Configuring Therapeutic Aspects of Immune Checkpoints in Lung CancerAvinash D. Khadela, Vivek P. Chavda, Humzah I. Postwala, Ramya Ephraim, Vasso Apostolopoulos, Yesha B. Shah · 2023 · Cancers
- Worldwide productivity and research trend of publications concerning tumor immune microenvironment (TIME): a bibliometric studyYao-Ge Liu, Shitao Jiang, Lei Zhang, Han Zheng, Ting Zhang, Junwei Zhang, Haitao Zhao, Xinting Sang, Yiyao Xu, Xin Lu · 2023 · European journal of medical research
- Development of thiolated xanthan gum-stearylamine conjugate based mucoadhesive system for the delivery of biochanin-A to melanoma cellsMahima Jadav, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari · 2023 · International Journal of Biological Macromolecules
- From antigen uptake to immune modulation: the multifaceted potential of peptide nanofibers as vaccine nanocarriersHatem A. F. M. Hassan, Mohamed Aly Haider, Sherif Ashraf Fahmy · 2024 · Materials Advances
- Biomarker development for PD-(L)1 axis inhibition: a consensus view from the SITC Biomarkers CommitteeAnne Monette, Sarah Warren, J. Carl Barrett, Charlie Garnett‐Benson, Kurt Alex Schalper, Janis Marie Taube, Brian Gregory Topp, Alexandra Snyder · 2024 · Journal for ImmunoTherapy of Cancer
- Co‐inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastomaLiliana E. Lucca, David A. Hafler · 2017 · Immunological Reviews
- Immunomodulatory effects of current cancer treatment and the consequences for follow-up immunotherapeuticsMeghan J. Mooradian, Ryan Joseph Sullivan · 2017 · Future Oncology
- From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials WiselyDaphne Day, Arta Monir Monjazeb, Elad Sharon, S. Percy Ivy, Eric H. Rubin, Gary L. Rosner, Marcus Otho Butler · 2017 · Clinical Cancer Research
- Hyperprogressive Disease and Early Hypereosinophilia After Anti-PD-1 Treatment: A Case ReportMario Alberto Occhipinti, Rosa Falcone, Concetta Elisa Onesti, Paolo Marchetti · 2018 · Drug Safety - Case Reports
- Current frontline approaches in the management of hepatocellular carcinoma: the evolving role of immunotherapyGagandeep Singh Brar, Tim F. Greten, Zachary J. Brown · 2018 · Therapeutic Advances in Gastroenterology
- Immune checkpoint blockade for Merkel cell carcinoma: actual findings and unanswered questionsNIKE Group, Marco Gallo, Valentina Guarnotta, Federica de Cicco, Manila Rubino, Antongiulio Faggiano, Annamaria Colao · 2019 · Journal of Cancer Research and Clinical Oncology
- Immunotherapy in Multiple Myeloma: Accelerating on the Path to the PatientIrene Ghobrial, Calixto Hernández Cruz, Alfred L. Garfall, Nina D. Shah, Nikhil C. Munshi, Jonathan L. Kaufman, Lawrence Boise, Gareth John Morgan, Viktor A. Adalsteinsson, Salomon Manier et al. · 2019 · Clinical Lymphoma Myeloma & Leukemia
- Reprogramming lymphocytes for the treatment of melanoma: From biology to therapyNaama Margolis, Ettai Markovits, Gal Markel · 2019 · Advanced Drug Delivery Reviews
- Landscape of Immune Checkpoint Inhibition in Carcinosarcoma (MMMT): Analysis of IDO-1, PD-L1 and PD-1Sean M. Hacking, Hector Chavarria, Cao Jin, Alexander C. Perry, Mansoor M. Nasim · 2020 · Pathology - Research and Practice
- Modulation of the Gut Microbiota Alters the Tumour-Suppressive Efficacy of Tim-3 Pathway Blockade in a Bacterial Species- and Host Factor-Dependent MannerBokyoung Lee, Jieun Lee, Min-Yeong Woo, Mi Jin Lee, Ho‐Joon Shin, Kyongmin Hwang Kim, Sun Park · 2020 · Microorganisms
- A novel antibody targeting TIM-3 resulting in receptor internalization for cancer immunotherapyZhihui Kuang, Li Li, Pan Zhang, Bingliang Chen, Min Wu, Haiqing Ni, Shuai Yi, Jia Zou, Junjian Liu · 2020 · Antibody Therapeutics
- Monoclonal Antibodies in Dermatooncology—State of the Art and Future PerspectivesMałgorzata Bobrowicz, Radosław Zagożdżon, Joanna Domagała, Roberta Vasconcelos‐Berg, Emmanuella Guenova, Magdalena Winiarska · 2019 · Cancers
- Emerging uses of biomarkers in lung cancer management: molecular mechanisms of resistanceShirin Attarian, Numa Rahman, Balázs Halmos · 2017 · Annals of Translational Medicine
- A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platformsYu-jia Jin, Diao Yu, Xiaolong Tian, Huixian Li, Xiao-Chao Zhou, Yu Kong, Wei Zhang, Lu Zhang, Lei Cheng, Zhenlin Yang et al. · 2021 · Acta Pharmacologica Sinica
- Targeting the HVEM protein using a fragment of glycoprotein D to inhibit formation of the BTLA/HVEM complexKatarzyna Kuncewicz, Claire Battin, Katarzyna E. Wegrzyn, Adam K. Sieradzan, Anna Wardowska, Emilia Sikorska, Irma Giedrojć, Pamela Smardz, Michał Pikuła, Peter Steinberger et al. · 2022 · Bioorganic Chemistry
- Novel antigens for targeted radioimmunotherapy in hepatocellular carcinomaMahsa Pourhamzeh, Samieh Asadian, Hamed Mirzaei, Azita Minaei, Elahe Shahriari, Anastasia I. Shpichka, Hamidreza Aboulkheyr Es, Peter S. Timashev, Moustapha Hassan, Massoud Vosough · 2022 · Molecular and Cellular Biochemistry
- On-demand integrated nano-engager converting cold tumors to hot via increased DNA damage and dual immune checkpoint inhibitionXiaoqing Liu, Shuang Liang, Xiao Sang, Lili Chang, Shunli Fu, Han Kwang Yang, Huizhen Yang, Yongjun Liu, Na Zhang · 2022 · Acta Pharmaceutica Sinica B