Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J. +18 more·2016·Nature Communications
Cited by (1,000)
Items 201–300 of 1,000
- Long-Term Survival in Patients Responding to Anti–PD-1/PD-L1 Therapy and Disease Outcome upon Treatment DiscontinuationMarie-Léa Gauci, Émilie Lanoy, Stéphane Champiat, Caroline Caramella, Samy Ammari, Sandrine Aspeslagh, Andréa Varga, Capucine Baldini, Rastilav Bahleda, Anas Gazzah et al. · 2018 · Clinical Cancer Research
- The Role of Cytokines in Predicting the Response and Adverse Events Related to Immune Checkpoint InhibitorsMin Wang, Xiaoyang Zhai, Ji Li, Jingyuan Guan, Shuhui Xu, Yuying Li, Hui Zhu · 2021 · Frontiers in Immunology
- Advances and prospects of biomarkers for immune checkpoint inhibitorsHirohito Yamaguchi, Jung-Mao Hsu, Linlin Sun, Shao‐Chun Wang, Mien‐Chie Hung · 2024 · Cell Reports Medicine
- Radiotherapy and anti-PD-1/PD-L1 combinations in lung cancer: building better translational research platformsTiana Kordbacheh, Jamie Honeychurch, Fiona Helen Blackhall, Corinne Faivre Finn, Tim Illidge · 2017 · Annals of Oncology
- Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapyZachary Davis, Daniel A. Vallera, Jeffrey S. Miller, Martin Felices · 2017 · Seminars in Immunology
- Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatmentGao, Zhifei, Bai, Yifeng, Lin, Anqi, Jiang, Aimin, Zhou, Chaozheng, Cheng, Quan, Liu, Zaoqu, Chen, Xin, Zhang, Jian, Luo, Peng · 2023 · Molecular Cancer
- Mechanisms of resistance to targeted therapy and immunotherapy in non-small cell lung cancer: promising strategies to overcoming challengesYuchu Xiang, Xudong Liu, Yifan Wang, Dawei Zheng, Qiuxing Meng, Lingling Jiang, Sha Yang, Sijia Zhang, Xin Zhang, Yan Liu et al. · 2024 · Frontiers in Immunology
- Targeting immune checkpoints in hematological malignanciesBasit Salik, Mark John Smyth, Kyohei Nakamura · 2020 · Journal of Hematology & Oncology
- Current and future perspectives of PD-1/PDL-1 blockade in cancer immunotherapyMakuku, Rangarirai, Khalili, Neda, Razi, Sepideh, Keshavarz-Fathi, Mahsa, Rezaei, Nima · 2021 · Journal of Immunology Research
- Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanismsHuang, Mu-Yang, Jiang, Xiao-Ming, Wang, Bing-Lin, Sun, Yang, Lu, Jin-Jian · 2021 · Pharmacology & Therapeutics
- Reinvigorating exhausted CD8 + cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapyMd Amir Hossain, Guilai Liu, Beiying Dai, Yaxuan Si, Qitao Yang, Junaid Wazir, Lutz Birnbaumer, Yong Yang · 2020 · Medicinal Research Reviews
- Direct and indirect regulation of the tumor immune microenvironment by VEGFYuqing Zhang, Rolf A. Brekken · 2022 · Journal of Leukocyte Biology
- Tim-3 expression and its role in hepatocellular carcinomaFeifei Liu, Yanning Liu, Zhi Chen · 2018 · Journal of Hematology & Oncology
- Unleashing Natural Killer Cells in the Tumor Microenvironment–The Next Generation of Immunotherapy?Aviad Ben‐Shmuel, Guy Biber, Mira Barda‐Saad · 2020 · Frontiers in Immunology
- TIM-3 as a promising target for cancer immunotherapy in a wide range of tumorsNatalia Julia Sauer, Natalia Janicka, Wojciech Szlasa, Bartłomiej Skinderowicz, Katarzyna Kołodzińska, Wioletta Dwernicka, Małgorzata Oślizło, Julita Kulbacka, Vitalij Novickij, Katarzyna Karłowicz-Bodalska · 2023 · Cancer Immunology Immunotherapy
- The Effectiveness of Checkpoint Inhibitor Combinations and Administration Timing Can Be Measured by Granzyme B PET ImagingBenjamin M. Larimer, Emily Bloch, Sarah Nesti, Emily E. Austin, Eric Paul Wehrenberg-Klee, Genevieve Marie Boland, Umar Mahmood · 2018 · Clinical Cancer Research
- Immune Checkpoint Targeted Therapy in Glioma: Status and HopesYangzhi Qi, Baohui Liu, Qian Sun, Xiaoxing Xiong, Qianxue Chen · 2020 · Frontiers in Immunology
- Mechanisms of Resistance to Immune Checkpoint BlockadeDavid Liu, Russell William Jenkins, Ryan Joseph Sullivan · 2018 · American Journal of Clinical Dermatology
- Toward Biomaterials for Enhancing Immune Checkpoint Blockade TherapyQin Fan, Zhipeng Chen, Chao Wang, Zhuang Liu · 2018 · Advanced Functional Materials
- Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patientsSunny Kumar, Mouli Chatterjee, Pratyasha Ghosh, Kirat Kumar Ganguly, Malini Basu, Mrinal K. Ghosh · 2022 · Genes & Diseases
- The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-DependentChloé Grasselly, Morgane Denis, Aurore Bourguignon, Nolan Talhi, Doriane Mathé, Anne Tourette, Laurent Serre, Lars Petter Jordheim, Eva Laure Matera, Charles Dumontet · 2018 · Frontiers in Immunology
- Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategiesYun Liu, Jianfeng Guo, Leaf Huang · 2020 · Theranostics
- The critical role of CD4+ T cells in PD-1 blockade against MHC-II–expressing tumors such as classic Hodgkin lymphomaJoji Nagasaki, Yosuke Togashi, Takeaki Sugawara, Makiko Itami, Nobuhiko Yamauchi, Junichiro Yuda, Masato Sugano, Yuuki Ohara, Yosuke Minami, Hirohisa Nakamae et al. · 2020 · Blood Advances
- Mechanisms of resistance to immune checkpoint inhibitorsJoji Nagasaki, Takamasa Ishino, Yosuke Togashi · 2022 · Cancer Science
- Multiparametric profiling of non–small-cell lung cancers reveals distinct immunophenotypesPatrick Hall Lizotte, Elena V. Ivanova, Mark Magdi Awad, Robert E. Jones, Lauren Keogh, Hongye Liu, Ruben Dries, Christina G. Almonte, Grit Sophie Herter-Sprie, Abigail A. Santos et al. · 2016 · JCI Insight
- Immune Checkpoint Inhibition in Head and Neck CancerMartin David Forster, Michael-John Devlin · 2018 · Frontiers in Oncology
- Clinical implications of the interaction between PD-1/PD-L1 and PI3K/AKT/mTOR pathway in progression and treatment of non-small cell lung cancerZihan Quan, Yang Yang, Hongmei Zheng, Yuting Zhan, Jiadi Luo, Yue Ning, Songqing Fan · 2022 · Journal of Cancer
- Recent developments in immunotherapy for gastrointestinal tract cancersXiaoyi Chong, Yelizhati Madeti, Jieyuan Cai, Wen‐Fei Li, Lin Cong, Jialin Lu, Liyang Mo, Huizhen Liu, Siyi He, Chao Yu et al. · 2024 · Journal of Hematology & Oncology
- Immune-checkpoint inhibitor resistance in cancer treatment: Current progress and future directionsChenyue Zhang, Chenxing Zhang, Haiyong Wang · 2023 · Cancer Letters
- The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapyXueping Wang, Fang Wang, Mengjun Zhong, Yosef Yarden, Liwu Fu · 2020 · Molecular Cancer
- Advanced nanomedicine approaches applied for treatment of skin carcinomaHarsimran Kaur, Prashant Kesharwani · 2021 · Journal of Controlled Release
- The Future of Immune Checkpoint Cancer Therapy After PD-1 and CTLA-4Andrew Warren Hahn, David Michael Gill, Sumanta Kumar Pal, Neeraj Agarwal · 2017 · Immunotherapy
- Targeting phosphatidylserine for Cancer therapy: prospects and challengesWenguang Chang, Hongge Fa, Dandan Xiao, Jianxun Wang · 2020 · Theranostics
- PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapyJunyu Long, Jianzhen Lin, Anqiang Wang, Liangcai Wu, Yongchang Zheng, Xiaobo Yang, Xueshuai Wan, Haifeng Xu, Shuguang Chen, Haitao Zhao · 2017 · Journal of Hematology & Oncology
- Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacyCatherine A. Sabatos-Peyton, James Timothy Nevin, Ansgar Brock, John D. Venable, Dewar J. Tan, Nasim Kassam, Fangmin Xu, John A. Taraszka, Luke David Wesemann, Thomas Pertel et al. · 2017 · OncoImmunology
- TGFβ pathway inhibition in the treatment of non-small cell lung cancerPınar Ö. Eser, Pasi Antero Janne · 2017 · Pharmacology & Therapeutics
- Indoleamine 2,3-dioxygenase provides adaptive resistance to immune checkpoint inhibitors in hepatocellular carcinomaZachary J. Brown, Su Jong Yu, Bernd Heinrich, Chi Ma, Qiong Fu, Milan Sandhu, David Agdashian, Qianfei Zhang, Firouzeh Korangy, Tim F. Greten · 2018 · Cancer Immunology Immunotherapy
- ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesotheliomaIsabelle Opitz, Arnaud Scherpereel, Thierry Berghmans, Ioannis Psallidas, Markus Glatzer, David Rigau Comas, Philippe J. Astoul, Servet Bölükbas, Jeanette Boyd, Johan Coolen et al. · 2020 · European Journal of Cardio-Thoracic Surgery
- Natural killer cell immunotherapies against cancer: checkpoint inhibitors and moreLaura Chiossone, Margaux Vienne, Yann M. Kerdiles, Éric Vivier · 2017 · Seminars in Immunology
- Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy lossYanhong Li, Jiayuan Zhang, Di Zhang, Xiaowu Hong, Tao Yu, Songcun Wang, Yuanyuan Xu, Hailan Piao, Weijie Yin, Min Yu et al. · 2017 · Science Signaling
- Breast Cancer Cells and PD-1/PD-L1 Blockade Upregulate the Expression of PD-1, CTLA-4, TIM-3 and LAG-3 Immune Checkpoints in CD4+ T CellsReem Saleh, Salman M. Toor, Sarah Khalaf, Eyad Elkord · 2019 · Vaccines
- Monitoring Immune Checkpoint Regulators as Predictive Biomarkers in Hepatocellular CarcinomaShrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R., Crawford, Darrell H. G., Dhungel, Bijay, Steel, Jason C., Jayachandran, Aparna · 2018 · Frontiers in Oncology
- Biomarkers Associated with Beneficial PD-1 Checkpoint Blockade in Non–Small Cell Lung Cancer (NSCLC) Identified Using High-Plex Digital Spatial ProfilingJon Zugazagoitia, Swati Gupta, Yuting Liu, Kit A. Fuhrman, Scott N. Gettinger, Roy S. Herbst, Kurt Alex Schalper, David L. Rimm · 2020 · Clinical Cancer Research
- FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor ActivityMatthew Kraman, Mustapha Faroudi, Natalie L. Allen, Katarzyna Kmiecik, Daniel Gliddon, Claire J. Seal, Alexander Koers, Mateusz M. Wydro, Sarah Batey, Julia Winnewisser et al. · 2020 · Clinical Cancer Research
- Clinical Insights Into Novel Immune Checkpoint InhibitorsJii Bum Lee, Sang‐Jun Ha, Hye Ryun Kim · 2021 · Frontiers in Pharmacology
- The Dynamic and Transient Immune Microenvironment in Locally Advanced Esophageal Adenocarcinoma Post ChemoradiationRonan Joseph Kelly, Ali Hussainy Zaidi, Matthew A. Smith, Ashten N. Omstead, Juliann E. Kosovec, Daisuke Matsui, Samantha A. Martin, Christina M. DiCarlo, E. Day Werts, Jan F. Silverman et al. · 2017 · Annals of Surgery
- Safety and Immunogenicity of LY3415244, a Bispecific Antibody Against TIM-3 and PD-L1, in Patients With Advanced Solid TumorsMatthew David Hellmann, Nicoletta Bivi, Boris Calderón, Toshio Shimizu, Brant Delafontaine, Zhuqing Tina Liu, Anna M. Szpurka, Victoria Copeland, Frank Stephen Hodi, Sylvie Rottey et al. · 2021 · Clinical Cancer Research
- Immunotherapy in Colorectal Cancer: Current and Future StrategiesAkira Ooki, Eiji Shinozaki, Kensei Yamaguchi · 2021 · Journal of the Anus Rectum and Colon
- Cancer Immunotherapy: A Focus on the Regulation of Immune CheckpointsTao Shi, Yanyu Ma, Lingfeng Yu, Jiaxuan Jiang, Sunan Shen, Yayi Hou, Tingting Wang · 2018 · International Journal of Molecular Sciences
- Immune checkpoint molecules soluble program death ligand 1 and galectin‐9 are increased in pregnancyElizabeth Ann L. Enninga, Susan M. Harrington, Douglas J. Creedon, Rodrigo Ruano, Svetomir N. Markovic, Haidong Dong, Roxana Stefania Dronca · 2017 · American Journal of Reproductive Immunology
- Immune Checkpoints and CAR-T Cells: The Pioneers in Future Cancer Therapies?Negar Hosseinkhani, Afshin Derakhshani, Omid Kooshkaki, Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh, Amir Baghbanzadeh, Hossein Safarpour, Ahad Mokhtarzadeh, Oronzo Brunetti, Simon C. Yue et al. · 2020 · International Journal of Molecular Sciences
- Development of CAR T cells designed to improve antitumor efficacy and safetyJanneke E. Jaspers, Renier J. Brentjens · 2017 · Pharmacology & Therapeutics
- Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistanceXiaoting Zhou, Yanghong Ni, Xiao Liang, Yi Lin, Biao An, Xiang He, Xia Zhao · 2022 · Frontiers in Immunology
- Histone lactylation-driven B7-H3 expression promotes tumor immune evasionZhibo Ma, Jianming Yang, Wenlong Jia, Le Li, Yixin Li, Junjie Hu, Wei Luo, Ronghui Li, Dawei Ye, Peixiang Lan · 2025 · Theranostics
- Reprogramming the breast tumor immune microenvironment: cold-to-hot transition for enhanced immunotherapySaber İmani, Reyhaneh Farghadani, Ghazaal Roozitalab, Mazaher Maghsoudloo, Mahdieh Emadi, Atefeh Moradi, Behnaz Abedi, Parham Jabbarzadeh Kaboli · 2025 · Journal of Experimental & Clinical Cancer Research
- Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approachesDongkui Song, Thomas B. Powles, Lei Shi, Lirong Zhang, Molly A. Ingersoll, Yong‐Jie Lu · 2019 · The Journal of Pathology
- PD-1 and LAG-3 Dominate Checkpoint Receptor–Mediated T-cell Inhibition in Renal Cell CarcinomaHenning Zelba, Jens Bedke, Jörg Hennenlotter, Sven Mostböck, Markus Zettl, Thomas Zichner, Anoop Chandran, Arnulf Stenzl, Hans‐Georg Rammensee, Cécile Gouttefangeas · 2019 · Cancer Immunology Research
- Current Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck CancerVictor C. Kok · 2020 · Frontiers in Oncology
- Current Developments and Challenges of mRNA VaccinesJinjin Chen, Jianzhu Chen, Qiaobing Xu · 2022 · Annual Review of Biomedical Engineering
- Fighting Drug Resistance through the Targeting of Drug-Tolerant Persister CellsDe Conti, Giulia, Dias, Matheus Henrique, Bernards, René · 2021 · Cancers
- Data Rich, Information Poor: Can We Use Electronic Health Records to Create a Learning Healthcare System for Pharmaceuticals?Hans‐Georg Eichler, Brigitte Bloechl‐Daum, Karl Broich, Paul Alexander Kyrle, Jillian Oderkirk, Guido Rasi, Rui Santos Ivo, Ad Schuurman, Thomas Senderovitz, Luke Slawomirski et al. · 2018 · Clinical Pharmacology & Therapeutics
- Targeting PD-1/PD-L-1 immune checkpoint inhibition for cancer immunotherapy: success and challengesSadique Akhtar Javed, Asim Najmi, Waquar Ahsan, Khalid A. Zoghebi · 2024 · Frontiers in Immunology
- Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and CancerIsobel Okoye, Michael Houghton, D. Lorne Tyrrell, Khaled Barakat, Shokrollah Elahi · 2017 · Frontiers in Immunology
- New emerging targets in cancer immunotherapy: the role of TIM3Alex Friedlaender, Alfredo Addeo, Giuseppe Luigi Banna · 2019 · ESMO Open
- Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and ProgressionReem Saleh, Salman M. Toor, Varun Sasidharan Nair, Eyad Elkord · 2020 · Frontiers in Immunology
- Advances in immunotherapy for glioblastoma multiformeAhmad Bakur Mahmoud, Reham Ajina, Sarah Aref, Manar Darwish, May A. Alsayb, Mustafa Taher, Shaker T. Alsharif, Anwar M. Hashem, Almohanad A. Alkayyal · 2022 · Frontiers in Immunology
- NK cells to cure cancerClara Di Vito, Joanna Mikulak, Elisa Zaghi, Silvia Pesce, Emanuela Marcenaro, Domenico Mavilio · 2019 · Seminars in Immunology
- Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapyPaola Dama, Marshall Tang, Noreen C. Fulton, Justin Paul Kline, Hongtao Liu · 2019 · Journal for ImmunoTherapy of Cancer
- Expression of lymphocyte immunoregulatory biomarkers in bone and soft-tissue sarcomasAmanda R. Dancsok, Nokitaka Setsu, Dongxia Gao, Jean‐Yves Blay, David Morgan Thomas, Robert G. Maki, Torsten O. Nielsen, Elizabeth G. Demicco · 2019 · Modern Pathology
- PD-1 silencing impairs the anti-tumor function of chimeric antigen receptor modified T cells by inhibiting proliferation activityJianshu Wei, Can Luo, Yao Wang, Yelei Guo, Hanren Dai, Chuan Tong, Dongdong Ti, Zhiqiang Wu, Weidong Han · 2019 · Journal for ImmunoTherapy of Cancer
- Targeting the Immune Microenvironment in the Treatment of Head and Neck Squamous Cell CarcinomaHui‐Ching Wang, Leong‐Perng Chan, Shih‐Feng Cho · 2019 · Frontiers in Oncology
- Targeting NK Cell Checkpoint Receptors or Molecules for Cancer ImmunotherapyCai Zhang, Yuxia Liu · 2020 · Frontiers in Immunology
- Cas9-edited immune checkpoint blockade PD-1 DNA polyaptamer hydrogel for cancer immunotherapyJaiwoo Lee, Quoc‐Viet Le, Geon Yang, Yu‐Kyoung Oh · 2019 · Biomaterials
- Sono/Photodynamic Nanomedicine‐Elicited Cancer ImmunotherapyYuce Li, Jun Xie, Wooram Um, Dong Gil You, Seunglee Kwon, Lianbin Zhang, Jintao Zhu, Jae Hyung Park · 2020 · Advanced Functional Materials
- Clinical definition of acquired resistance to immunotherapy in patients with metastatic non-small-cell lung cancerAdam Jacob Schoenfeld, Scott Joseph Antonia, Mark Magdi Awad, Enriqueta Felip, Justin F. Gainor, Scott N. Gettinger, Frank Stephen Hodi, Melissa Lynne Johnson, Natasha B. Leighl, Christine Marie Lovly et al. · 2021 · Annals of Oncology
- Immune checkpoint proteins PD-1 and TIM-3 are both highly expressed in liver tissues and correlate with their gene polymorphisms in patients with HBV-related hepatocellular carcinomaLi Zhu, Na Li, Fang Li, Zhi-Hua Zhou, Jiao Sang, Yanping Chen, Qunying Han, Yi Lv, Zhengwen Liu · 2016 · Medicine
- Small-Molecule Immune Checkpoint Inhibitors Targeting PD-1/PD-L1 and Other Emerging Checkpoint PathwaysPottayil G. Sasikumar, Murali Ramachandra · 2018 · BioDrugs
- Immune overdrive signature in colorectal tumor subset predicts poor clinical outcomeFakih, Marwan, Ouyang, Ching, Wang, Chongkai, Tu, Travis Yiwey, Gozo, Maricel C., Cho, May, Sy, Marvin, Longmate, Jeffrey A., Lee, Peter P. · 2019 · Journal of Clinical Investigation
- Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination TreatmentsAnje Cauwels, Sandra Van Lint, Franciane Paul, Geneviève Garcin, Stefaan De Koker, Alexander Van Parys, Thomas Wueest, Sarah Gerlo, José Van der Heyden, Yann Bordat et al. · 2017 · Cancer Research
- CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancerPaulino Tallón de Lara, Héctor Castañón, Marijne Vermeer, Nicolás Gonzalo Núñez, Karīna Siliņa, Bettina Sobottka, Joaquín Urdinez, Virginia Cecconi, Hideo Yagita∥, Farkhondeh Movahedian Attar et al. · 2021 · Nature Communications
- Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cellsVeronika Bachanová, Dhifaf Sarhan, Todd E. DeFor, Sarah Cooley, Angela Panoskaltsis‐Mortari, Bruce R. Blazar, Julie Curtsinger, Linda J. Burns, Daniel Jordan Weisdorf, Jeffrey S. Miller · 2017 · Cancer Immunology Immunotherapy
- A Multi-center Phase I Trial of Ipilimumab in Patients with Myelodysplastic Syndromes following Hypomethylating Agent FailureAmer Methqal Zeidan, Hanna A. Knaus, Tara M. Robinson, Andrea M. H. Towlerton, Edus Houston Warren, Joshua F. Zeidner, Amanda L. Blackford, Amy S. Duffield, David Alan Rizzieri, Mark G. Frattini et al. · 2018 · Clinical Cancer Research
- Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for CancerDonghai Xiong, Yian Wang, Arun K. Singavi, Alexander Craig Mackinnon, Ben George, Ming You · 2018 · iScience
- Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytesJie Liu, Shuo Yang, Bihui Cao, Guangyu Zhou, Fengjuan Zhang, Yuan Wang, Rixin Wang, Lipeng Zhu, Ya Meng, Cong Hu et al. · 2021 · Journal of Hematology & Oncology
- Challenges in glioblastoma immunotherapy: mechanisms of resistance and therapeutic approaches to overcome themHabashy, Karl John, Mansour, Rana, Moussalem, Charbel, Sawaya, Raymond, Massaad, Michel J. · 2022 · British Journal of Cancer
- Immunotherapies for the Treatment of Uveal Melanoma—History and FutureTimo E. Schank, Jessica C. Hassel · 2019 · Cancers
- The current state of immunotherapy for gliomas: an eye toward the futurePeter Edward Fecci, John Howard Sampson · 2019 · Journal of neurosurgery
- Harnessing NK Cells for Cancer TreatmentPaola Minetto, Fabio Guolo, Silvia Pesce, Marco Greppi, Valentina Obino, Elisa Ferretti, Simona Sivori, Carlo Genova, Roberto Massimo Lemoli, Emanuela Marcenaro · 2019 · Frontiers in Immunology
- Oncogenic signaling pathways associated with immune evasion and resistance to immune checkpoint inhibitors in cancerYoshie Kobayashi, Seung‐Oe Lim, Hirohito Yamaguchi · 2019 · Seminars in Cancer Biology
- New insights into the pharmacological, immunological, and CAR-T-cell approaches in the treatment of hepatocellular carcinomaMichele Dal Bo, Elena De Mattia, Lorena Baboçi, Silvia Mezzalira, Erika Cecchin, Yehuda G. Assaraf, Giuseppe Toffoli · 2020 · Drug Resistance Updates
- Palmitoylation of TIM-3 promotes immune exhaustion and restrains antitumor immunityZhaoying Zhang, Caiyue Ren, Rong Xiao, Shuaiya Ma, Huimin Liu, Yutong Dou, Yu‐Chen Fan, Shuo Wang, Peng Zhan, Chengjiang Gao et al. · 2024 · Science Immunology
- Immune regulation by Tim-3Hridesh Banerjee, Larry Kane · 2018 · F1000Research
- Immune Checkpoint Inhibitors in Hepatocellular Cancer: Current Understanding on Mechanisms of Resistance and Biomarkers of Response to TreatmentAmblessed E. Onuma, Hongji Zhang, Hai Huang, Terence Marques Williams, Anne M. Noonan, Allan Tsung · 2020 · Gene Expression
- Identifying key questions in the ecology and evolution of cancerAntoine Marie Dujon, Athena Aktipis, Catherine Alix‐Panabières, Sarah R. Amend, Amy M. Boddy, Joel S. Brown, Jean‐Pascal Capp, James V. DeGregori, Paul W. Ewald, Robert A. Gatenby et al. · 2020 · Evolutionary Applications
- Immune Checkpoint Inhibitors in Colorectal Cancer: Challenges and Future ProspectsShima Makaremi, Zahra Asadzadeh, Nima Hemmat, Amir Baghbanzadeh, Alessandro Sgambato, Farid Ghorbaninezhad, Hossein Safarpour, Antonella Argentiero, Oronzo Brunetti, Renato Bernardini et al. · 2021 · Biomedicines
- Mechanisms, combination therapy, and biomarkers in cancer immunotherapy resistanceManshi Yang, Mengying Cui, Yang Sun, Shui Liu, Weibo Jiang · 2024 · Cell Communication and Signaling
- Resistance to immune checkpoint inhibitors in non-small cell lung cancer: biomarkers and therapeutic strategiesRobert John Walsh, Ross Andrew Soo · 2020 · Therapeutic Advances in Medical Oncology
- Targeting Tim-3 in Cancer With Resistance to PD-1/PD-L1 BlockadeTian Tian, Zhaoming Li · 2021 · Frontiers in Oncology
- Emerging therapeutic agents for lung cancerBhagirathbhai Dholaria, William A. Hammond, Amanda J. Shreders, Yanyan Lou · 2016 · Journal of Hematology & Oncology
- Effect of physicochemical properties on in vivo fate of nanoparticle-based cancer immunotherapiesYongchao Wang, Jinjin Wang, Dandan Zhu, Yufei Wang, Guangchao Qing, Yuxuan Zhang, Xiaoxuan Liu, Xing‐Jie Liang · 2021 · Acta Pharmaceutica Sinica B