Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

Young, Andrew L., Challen, Grant A., Birmann, Brenda M., Druley, Todd E.·2016·Nature Communications

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  19. Faculty Opinions recommendation of The emerging clinical relevance of genomics in cancer medicine.
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  27. Faculty Opinions recommendation of Analysis of error profiles in deep next-generation sequencing data.
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