VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease

Guo, Xing, Sun, XiaoYan, Hu, Di, Wang, Ya-Juan, Fujioka, Hisashi, Vyas, Rajan, Chakrapani, Sudha, Joshi, Amit Umesh, Luo, Yu, Mochly-Rosen, Daria, Qi, Xin·2016·Nature Communications

Cited by (200)

Items 101–200 of 200

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  10. Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis
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  12. Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington Disease
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  15. Mitochondrial biogenesis in organismal senescence and neurodegeneration
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  16. Tau accumulation is cleared by the induced expression of VCP via autophagy
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  17. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex
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