The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme
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Cites
Coot : model-building tools for molecular graphics
Emsley, P., & Cowtan, K. (2004) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444904019158 · Cited by 30,571
PHENIX : a comprehensive Python-based system for macromolecular structure solution
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Kabsch, W. (2010) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444909047337 · Cited by 16,463
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Adams, P. D., Afonine, P. V., Bunkóczi, G., Chen, V. B., Davis, I. W., Echols, N., Headd, J. J., Hung, L.-W., Kapral, G. J., Grosse-Kunstleve, R. W., et al. (2012) · International Tables for Crystallography · doi:10.1107/97809553602060000865 · Cited by 7,334
Scaling and assessment of data quality
Evans, P. (2006) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444905036693 · Cited by 4,374
Enzyme promiscuity: A mechanistic and evolutionary perspective
Tawfik, O. K. A. D. S. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-030409-143718 · Cited by 1,355
Exploring protein fitness landscapes by directed evolution
Romero, P. A., & Arnold, F. H. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2805 · Cited by 1,161
The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters
Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S., & Milo, R. (2011) · Biochemistry · doi:10.1021/bi2002289 · Cited by 1,050
Self-citationProtein Dynamism and Evolvability
Tokuriki, N., & Tawfik, D. S. (2009) · Science · doi:10.1126/science.1169375 · Cited by 940
Self-citationStability effects of mutations and protein evolvability
Tokuriki, N., & Tawfik, D. S. (2009) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2009.08.003 · Cited by 834
Self-citation
Cited by
Ferreiro, D. U., Komives, E. A., & Wolynes, P. G. (2014) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583514000092 · Cited by 314
The role of protein dynamics in the evolution of new enzyme function
Campbell, E., Kaltenbach, M., Correy, G. J., Carr, P. D., Porebski, B. T., Livingstone, E. K., Afriat-Jurnou, L., Buckle, A. M., Weik, M., Hollfelder, F., et al. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2175 · Cited by 311
Self-citationHeckmann, D., Lloyd, C. J., Mih, N., Ha, Y., Zielinski, D. C., Haiman, Z. B., Desouki, A. A., Lercher, M. J., & Palsson, B. O. (2018) · Nature Communications · doi:10.1038/s41467-018-07652-6 · Cited by 218
Protein representations: Encoding biological information for machine learning in biocatalysis
Harding-Larsen, D., Funk, J., Madsen, N. G., Gharabli, H., Acevedo-Rocha, C. G., Mazurenko, S., & Welner, D. H. (2024) · Biotechnology Advances · doi:10.1016/j.biotechadv.2024.108459 · Cited by 38
(2024) · doi:10.1038/s41467-024-47588-8 · Cited by 30
Metadata
- Authors
- Tokuriki, N., Jackson, C. J., Afriat-Jurnou, L., Wyganowski, K. T., Tang, R., & Tawfik, D. S.
- Venue
- Nature Communications
- Published
- 2012-12-04
- Volume
- 3
- Issue
- 1
- Pages
- 1257-1257
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2000054450
- Cited by
- 253
- References
- 52
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Tokuriki, N., Jackson, C. J., Afriat-Jurnou, L., Wyganowski, K. T., Tang, R., & Tawfik, D. S. (2012). Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme. Nature Communications. https://doi.org/10.1038/ncomms2246
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
