The role of protein dynamics in the evolution of new enzyme function

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Protein Dynamism and Evolvability

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Synthetic, Switchable Enzymes

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At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?

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A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis

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Modelling dynamics in protein crystal structures by ensemble refinement

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Challenges in Enzyme Mechanism and Energetics

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Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme

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The universality of enzymatic rate–temperature dependency

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Taking Ockham's razor to enzyme dynamics and catalysis

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Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD

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Enzyme dynamics point to stepwise conformational selection in catalysis

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Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

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Divergent evolution of protein conformational dynamics in dihydrofolate reductase

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From Enzyme Models to Model Enzymes

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Negative Epistasis and Evolvability in TEM-1 β-Lactamase—The Thin Line between an Enzyme's Conformational Freedom and Disorder

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Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

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