Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

Frenkel, Dan, Wilkinson, Kim, Zhao, Lingzhi, Hickman, Suzanne E., Means, Terry K., Puckett, Lindsay, Farfara, Dorit, Kingery, Nathan D. +2 more·2013·Nature Communications

DOI 10.1038/ncomms3030

Cited by (217)

Items 101–200 of 217

Role of the Retromer Complex in Neurodegenerative Diseases
Chaosi Li, Syed Zahid Ali Shah, Deming Zhao, Lifeng Yang · 2016 · Frontiers in Aging Neuroscience
Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression
Lucia Carboni, Luca Marchetti, Mario Lauria, Peter Gass, Barbara Vollmayr, Amanda J. Redfern, Lesley Jones, Maria Razzoli, Karim Malki, Veronica Begni et al. · 2018 · Neuropsychopharmacology
MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression
Xin Chen, Jiebang Jiang, Hailong Liu, Ajian Li, Wenchao Wang, Zhizhan Ni, Moubin Lin · 2022 · International Immunopharmacology
Anti-inflammatory and protective effects of MT-031, a novel multitarget MAO-A and AChE/BuChE inhibitor in scopolamine mouse model and inflammatory cells
Wei Liu, Alon Rabinovich, Yuval Nash, Dan Frenkel, Yuqiang Wang, Moussa B. H. Youdim, Orly Weinreb · 2016 · Neuropharmacology
Human Umbilical Cord Blood-Derived Monocytes Improve Cognitive Deficits and Reduce Amyloid-β Pathology in PSAPP Mice
Donna Darlington, Song Li, Huayan Hou, Ahsan Habib, Jun Tian, Yang Gao, Jared C. Ehrhart, Paul R. Sanberg, Darrell R. Sawmiller, Brian N. Giunta et al. · 2015 · Cell Transplantation
The effects of a 20-week exercise program on blood-circulating biomarkers related to brain health in overweight or obese children: The ActiveBrains project
María Rodríguez‐Ayllón, Abel Plaza‐Florido, Andrea Méndez-Gutiérrez, Signe Altmäe, Patricio Solis‐Urra, Concepción María Aguilera, Andrés Catena, Francisco B. Ortega, Irene Esteban‐Cornejo · 2022 · Journal of sport and health science/Journal of Sport and Health Science
Bridging the Gap between Alzheimer’s Disease and Alzheimer’s-like Diseases in Animals
Anita Gołaszewska, Wojciech Bik, T. Motyl, Arkadiusz Orzechowski · 2019 · International Journal of Molecular Sciences
Somatostatin Receptor Subtype-4 Regulates mRNA Expression of Amyloid-Beta Degrading Enzymes and Microglia Mediators of Phagocytosis in Brains of 3xTg-AD Mice
Karin E. Sandoval, David S. Umbaugh, Austin House, A. Michael Crider, KEN A. WITT · 2019 · Neurochemical Research
Physiological and pathogenic role of scavenger receptors in humans
Evgeni Gusev, N. V. Zotova, Yulia A. Zhuravleva, В. А. Черешнев · 2020 · Medical Immunology (Russia)
The age-related microglial transformation in Alzheimer's disease pathogenesis
Chunxu Yuan, Ailikemu Aierken, Zhen Xie, Nuomin Li, Juan Zhao, Hong Qing · 2020 · Neurobiology of Aging
Heart and Brain: Complex Relationships for Left Ventricular Dysfunction
Gianlorenzo Daniele, Stephanie DiLucia, Pier Giorgio Masci, Federica del Monte · 2020 · Current Cardiology Reports
Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence
Diana L. Núñez-Ríos, José Jaime Martínez‐Magaña, Sheila T. Nagamatsu, Diego Andrade-Brito, Diego A. Forero, Carlos A. Orozco, Janitza L. Montalvo‐Ortiz · 2022 · Biomedicines
Challenges in the treatment of Alzheimer’s disease: recent progress and treatment strategies of pharmaceuticals targeting notable pathological factors
Yung‐Chih Kuo, Rajendiran Rajesh · 2019 · Expert Review of Neurotherapeutics
Microglia in Alzheimer’s Disease
Patrick Süß, Johannes C. M. Schlachetzki · 2020 · Current Alzheimer Research
T cells in the brain inflammation
Akihiko Yoshimura, Masaki Ohyagi, Minako Ito · 2022 · Advances in immunology
Inhibition of Smad3 in macrophages promotes Aβ efflux from the brain and thereby ameliorates Alzheimer's pathology
Lu Xu, Cailong Pan, Xiang‐Hui Wu, Jingjing Song, Ping Meng, Lei Li, Li Wang, Zhiren Zhang, Zhi-Yuan Zhang · 2021 · Brain Behavior and Immunity
Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines
Philipp Spitzer, Matthias Walter, Caroline Göth, Timo Jan Oberstein, Philipp Linning, Hans‐Joachim Knölker, Johannes Kornhuber, Juan Manuel Maler · 2020 · Frontiers in Immunology
The Chemokine-like Receptor 1 Deficiency Improves Cognitive Deficits of AD Mice and Attenuates Tau Hyperphosphorylation via Regulating Tau Seeding
Zhang, Haibo, Lin, Aihua, Gong, Ping, Chen, Yanqing, Ye, Richard D., Qian, Feng, Zhang, Yan, Yu, Yang · 2020 · The Journal of Neuroscience
Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration
Guilherme Povala, Bruna Bellaver, Marco Antônio De Bastiani, João Pedro Ferrari‐Souza, Cristiano Schaffer Aguzzoli, Douglas Teixeira Leffa, Pâmela C.L. Ferreira, Firoza Zubeida Lussier, Andréia Silva da Rocha, Hussein Zalzale et al. · 2025 · Alzheimer s & Dementia
Microglia-Mediated Phagocytosis in Alzheimer’s Disease: Mechanisms, Heterogeneity, and Therapeutic Insights
Halimatu Hassan, Charlotte Rawlinson, Yu‐Long Lan, Stuart Iain Jenkins, Ruoli Chen · 2025 · Biomolecules
Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis
Burcu Zeydan, Val J. Lowe, Ross R. Reichard, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Jeffrey L. Gunter, Joseph E. Parisi, Mary M. Machulda et al. · 2020 · Annals of Neurology
Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation
Sho Takatori, Mayuna Kondo, Taisuke Tomita · 2025 · Inflammation and Regeneration
PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
Ryan, Christine B., Choi, James S., Kang, Brian, Herr, Seth, Pereira, Claudia, Moraes, Carlos T., Al-Ali, Hassan, Lee, Jae K. · 2024 · Neurobiology of Disease
Hyperbaric oxygen therapy as a new treatment approach for Alzheimer’s disease
Uri Ashery, Ronit Shapira, Shai Efrati · 2018 · Neural Regeneration Research
Prion protein and prion disease at a glance
Caihong Zhu, Adriano Aguzzi · 2021 · Journal of Cell Science
cGAS-STING signaling in Alzheimer's disease: Microglial mechanisms and therapeutic opportunities
Faaizah Fazal, Nawab John Dar, Shakir Ahamad, Sameera Khan, Nargis Bano, Supriyo Saha, Aamir Nazir, Shahnawaz Ali Bhat · 2026 · Molecular Aspects of Medicine
Trajectory of brain-derived amyloid beta in Alzheimer’s disease: where is it coming from and where is it going?
Ni Liu, Anaer Haziyihan, Wei Guang Zhao, Yu Chen, Hongbo Chao · 2024 · Translational Neurodegeneration
Propionate Decreases Microglial Activation but Impairs Phagocytic Capacity in Response to Aggregated Fibrillar Amyloid Beta Protein
Andrew Gold, Sarah D. Kaye, Jie Gao, Jiangjiang Zhu · 2024 · ACS Chemical Neuroscience
Umbilical Cord Mesenchymal Stem Cells Conditioned Medium Promotes Aβ25-35 phagocytosis by Modulating Autophagy and Aβ-Degrading Enzymes in BV2 Cells
Zhihao Xu, Wenbin Nan, Xiaoyue Zhang, Yuliang Sun, Jichao Yang, Kecheng Lu, Yalin Liu, Yaoxin Gao, Fen Yang, Wenchao Mao et al. · 2018 · Journal of Molecular Neuroscience
Clasmatodendrosis and β‐amyloidosis in aging hippocampus
Raffaella Mercatelli, Daniele Lana, Monica Bucciantini, Maria Grazia Giovannini, Francesca Cerbai, Franco Quercioli, Sandra Zecchi‐Orlandini, Giovanni Delfino, Gary L. Wenk, Daniele Nosi · 2015 · The FASEB Journal
Towards early diagnosis of Alzheimer’s disease: advances in immune-related blood biomarkers and computational approaches
Sophia Krix, Ella Wilczynski, Neus Falgàs, Raquel Sánchez‐Valle, Eti Yoles, Uri Nevo, Kuti Baruch, Holger Fröhlich · 2024 · Frontiers in Immunology
Metabolomic research on the role of interleukin-4 in Alzheimer’s disease
Raúl González‐Domínguez, Tamara García‐Barrera, Javier Vitórica, José Luis Gómez‐Ariza · 2015 · Metabolomics
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
Hayato Etani, Sho Takatori, Wenbo Wang, Jumpei Omi, Yusuke Amiya, Aika Akahori, Hirotaka Watanabe, Iki Sonn, Hideyuki Okano, Norikazu Hara et al. · 2025 · Alzheimer s Research & Therapy
Modulation of Innate Immunity by Amyloidogenic Peptides
Clara Y. Westwell-Roper, C. Bruce Verchere · 2019 · Trends in Immunology
Pathogenesis and therapeutic applications of microglia receptors in Alzheimer’s disease
Jiao Fu, RuoXuan Wang, JiHui He, Xiaojing Liu, Xinxin Wang, JuMing Yao, Ye Liu, Chongzhao Ran, Qingsong Ye, Yan He · 2025 · Frontiers in Immunology
Unraveling the β-amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPα, and class-A scavenger receptor
Daniela Durand, Juan Turati, María Julieta Rudi, Delia Ramírez, Julieta Saba, Carla M. Caruso, Lila Carniglia, Rommy von Bernhardi M., Mercedes Lasaga · 2019 · Neurochemistry International
Space-Dependent Glia–Neuron Interplay in the Hippocampus of Transgenic Models of β-Amyloid Deposition
Daniele Lana, Filippo Ugolini, Maria Grazia Giovannini · 2020 · International Journal of Molecular Sciences
Microglial Dysfunction and Amyloid-Beta Pathology in Alzheimer’s Disease and HIV-Associated Neurocognitive Disorders
George Chigozie Njoku, Georgette D. Kanmogne · 2025 · International Journal of Molecular Sciences
MSR1 and NEP Are Correlated with Alzheimer’s Disease Amyloid Pathology and Apolipoprotein Alterations
Justin Miron, Cynthia Picard, Anne Labonté, Daniel S. Auld, Judes Poirier · 2022 · Journal of Alzheimer s Disease
Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting
Karin E. Sandoval, KEN A. WITT · 2024 · Pharmacological Reviews
Boosting peripheral immunity to fight neurodegeneration in the brain
Michal Schwartz, Sarah Phoebeluc Colaiuta · 2024 · Trends in Immunology
Analysis of Surface Levels of IL-1 Receptors and Macrophage Scavenger Receptor I in Peripheral Immune Cells of Patients With Alzheimer Disease
Philipp Spitzer, Johannes Weinbeer, Martin Herrmann i, Timo Jan Oberstein, Mateja Condic, Piotr Lewczuk, Johannes Kornhuber, Juan Manuel Maler · 2019 · Journal of Geriatric Psychiatry and Neurology
The effects of enhancing angiotensin converting enzyme in myelomonocytes on ameliorating Alzheimer’s-related disease and preserving cognition
Ron Danziger, Dieu-Trang S. Fuchs, Yosef Koronyo, Altan Rentsendorj, Julia Sheyn, Eric Y. Hayden, David B. Teplow, Keith L. Black, Sébastien Fuchs, Kenneth E. Bernstein et al. · 2023 · Frontiers in Physiology
The Impact of Ag Nanoparticles and CdTe Quantum Dots on Expression and Function of Receptors Involved in Amyloid-β Uptake by BV-2 Microglial Cells
Katarzyna Sikorska, Iwona Grądzka, Iwona Wasyk, Kamil Brzóska, Tomasz Maciej Stępkowski, Malwina Czerwińska, Marcin K. Kruszewski · 2020 · Materials
Customer Behaviour Segmentation Among Mobile Service Providers In Kenya Using K-Means Algorithm
Khamis Mwero Maneno, Richard Maina Rimiru, Calvins Otieno · 2018 · Zenodo (CERN European Organization for Nuclear Research)
Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia
Xiaoyue Aelita Zhu, Joseph M. Schrader, Brandon A. Irizarry, Steven O. Smith, William E. Van Nostrand · 2022 · Biomedicines
Cytosolic Phospholipase A2 Facilitates Oligomeric Amyloid-β Peptide Association with Microglia via Regulation of Membrane-Cytoskeleton Connectivity
Tao Teng, Li Dong, Devin M. Ridgley, Shivesh Ghura, Matthew Kyle Tobin, Grace Y. Sun, Mary Jo LaDu, James C. Lee · 2018 · Molecular Neurobiology
Potential therapeutic natural compounds for the treatment of Alzheimer's disease
Qihui Huang, Weihao Wu, Yuxi Wen, Suyue Lu, Chao Zhao · 2024 · Phytomedicine
Microglia-neuron crosstalk in Alzheimer’s disease: an exploration of molecular mechanisms and pathological implications
Xizhen Kang, Jun Tian, Qing Shu, Tingting Cheng, Shanshan Wang, Yan Hu · 2025 · Neuroscience
Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease
Jie Pan, Jie Zhong, Ji Geng, Jane Oberhauser, Shihua Shi, Jun Wan · 2024 · Advanced Science
Microglia in Alzheimer’s Disease: A Favorable Cellular Target to Ameliorate Alzheimer’s Pathogenesis
Dewan Md. Sumsuzzman, Md. Sahab Uddin, Md. Tanvir Kabir, Sharifa Hasana, Asma Perveen, Ibtesam S. Alanazi, Ghadeer Mohsen Albadrani, Mohamed M. Abdel‐Daim, Ghulam Md Ashraf · 2022 · Mediators of Inflammation
Chronic stress leads to earlier cognitive decline in an Alzheimer’s mouse model: The role of neuroinflammation and TrkB
Shir Shlomi-Loubaton, Keren Nitzan, Maria Rivkin-Natan, Salomé Sabbah, Roni Toledano, Motty Franko, Ziv Bentulila, Dekel David, Dan Frenkel, Ravid Doron · 2025 · Brain Behavior and Immunity
NNC 26-9100 increases Aβ1-42 phagocytosis, inhibits nitric oxide production and decreases calcium in BV2 microglia cells
Joseph Martin Schober, Jahnavi Polina, Field Walters, Nathan R. Scott, Eric Lodholz, A. Michael Crider, Karin E. Sandoval, KEN A. WITT · 2021 · PLoS ONE
Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice
Dorit Farfara, Meital Sooliman, Limor Avrahami, Tabitha Grace Royal, Shoshik Amram, Lea Rozenstein‐Tsalkovich, Dorit Trudler, Shani Blanga‐Kanfi, Hagit Eldar-Finkelman, Jens Pahnke et al. · 2023 · Journal of Neuroinflammation
INPP5D/SHIP1 regulates inflammasome activation in human microglia
Chou, Vicky, Fancher, Seeley B., Pearse, Richard V., Lee, Hyo, Lam, Matti, Seyfried, Nicholas T., Bennett, David A., De Jager, Phillip L., Menon, Vilas, Young-Pearse, Tracy L. · 2023
Novel Somatostatin Receptor-4 Agonist SM-I-26 Mitigates Lipopolysaccharide-Induced Inflammatory Gene Expression in Microglia
Ashok Silwal, Austin House, Karin E. Sandoval, Shaluah Vijeth, David S. Umbaugh, A. Michael Crider, Shirin Mobayen, William L. Neumann, KEN A. WITT · 2021 · Neurochemical Research
The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis
Li, Bei, Chen, Meiling, Aguzzi, Adriano, Zhu, Caihong · 2021 · Journal of Molecular Medicine
Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease
Xin Huang, Yihan Li, Christopher James Fowler, James D. Doecke, Yen Ying Lim, Candace Drysdale, Vicky Zhang, Keunha Park, Brett O. Trounson, Kelly Kathleen Pertile et al. · 2022 · Alzheimer s & Dementia
Roles of microglial membranes in Alzheimer's disease
Jae‐Won Shin, James C. Lee · 2020 · Current topics in membranes
NGF Released from Blood Cells or Collagen Hydrogels as a Therapeutic Target in Alzheimer’s Disease?
Christian Humpel · 2021 · Advances in experimental medicine and biology
Administration of recombinant FOXN1 protein attenuates Alzheimer’s pathology in mice
Jin Xia Zhao, Zhenzhen Zhang, Kuan Chen Lai, Laijun Lai · 2023 · Brain Behavior and Immunity
Promoting active learning of graduate student by deep reading in biochemistry and microbiology pharmacy curriculum
Ren Peng · 2017 · Biochemistry and Molecular Biology Education
A network approach to compute hypervolume under receiver operating characteristic manifold for multi‐class biomarkers
Qunqiang Feng, Pan Liu, Pei Fen Kuan, Fei Zou, Jianan Chen, Jialiang Li · 2023 · Statistics in Medicine
Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression
Daniele Lana, Filippo Ugolini, Ludovica Iovino, Selene Attorre, Maria Grazia Giovannini · 2025 · Frontiers in Cellular Neuroscience
Annual stability of the plasma Aß40/42 ratio and associated factors
Takumi Nakamura, Takeshi Kawarabayashi, Naoko Nakahata, Ken Itoh, Kazushige Ihara, Shigeyuki Nakaji, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji · 2023 · Annals of Clinical and Translational Neurology
Corticosteroid treatment of Alzheimer's disease: is S100A9/Mrp14 a key target?
Fuyuki Kametani · 2013 · Neurobiology of Aging
Why Creating Transmissible Microbial Interferon Factories May Bring a Promise of a “Golden Era” in Future Human and Animal Health
Theodor-Nicolae Carp · 2025 · Preprints.org
Exploring the vital role of microglial membrane receptors in Alzheimer’s disease pathogenesis: a comprehensive review
JUN-FENG ZHAO, YI-RAN JIANG, TIAN-LIN GUO, YONG-QING JIAO, XUN WANG · 2024 · Biocell
Immunotherapy with a short-lived anti-PD-L1 antibody in Alzheimer’s disease: a phase 1b, randomized, double-blind trial
Tommaso Croese, Catherine Jane Mummery, Noa Bregman, Dalia Bracha, Kuti Baruch, Alexander Kertser, Sharona Raveh, Eliezer Shochat, Michal Schwartz · 2026 · Nature Medicine
Truncated GPNMB , a microglial transmembrane protein, serves as a scavenger receptor for oligomeric β‐amyloid peptide 1‐42 in primary type 1 microglia
Kohichi Kawahara, Takuya Hasegawa, Noa Hasegawa, Taisei Izumi, Koji Sato, Toshiyuki Sakamaki, Masayuki Ando, Takehiko Maeda · 2024 · Journal of Neurochemistry
An overview on the impact of viral pathogens on Alzheimer's disease
Melika AmeliMojarad, Mandana AmeliMojarad, Xiaonan Cui · 2024 · Ageing Research Reviews
Aging Microglia and Their Impact in the Nervous System
Rommy von Bernhardi M., Jaime L. Eugenín · 2024 · Advances in neurobiology
The role of immunity and neuroinflammation in genetic predisposition and pathogenesis of Alzheimer’s disease
Seoyoung Yoon, Yong‐Ku Kim · 2015 · Global Medical Genetics
Promise of Mindfulness-Based Interventions as Therapies to Prevent Cognitive Decline
Daniel M. Sapozhnikov · 2015 · McGill Science Undergraduate Research Journal
Variant-to-function mapping of late-onset Alzheimer’s disease GWAS signals in human microglial cell models implicates <i>RTFDC1</i> at the <i>CASS4</i> locus
Burton, Elizabeth A., Argenziano, Mariana, Cook, Kieona, Ridler, Molly, Lu, Sumei, Su, Chun, Manduchi, Elisabetta, Littleton, Sheridan H., Leonard, Michelle E., Hodge, Kenyaita M. et al. · 2024
Nasal administration of Protollin enhances monocyte phagocytosis and decreases CD8+ T cell cytotoxicity in subjects with early Alzheimer’s disease: a Phase 1 clinical trial
Panayota Kolypetri, Patrick da Silva, Ronaldo da Silva Francisco, Dan Frenkel, Rachael R. Cecere, Pien C.J. Kiliaan, Federico Montini, Shrishti Saxena, William A. Clementi, Xuejun Liu et al. · 2026 · npj Aging
Epigenetic control of microglial mitochondrial immunity by KAT7 drives Alzheimer’s disease pathogenesis
Yongqing Liu, Yingzhi Ye, Minghua Fan, Yi Cheng, Shuying Sun, Zhaozhu Qiu · 2026 · Neuron
Neurological‐related proteomic profiling in plasma of children with metabolic healthy and unhealthy overweight/obesity
Marcos Olvera‐Rojas, Abel Plaza‐Florido, Patricio Solis‐Urra, Francisco J. Osuna‐Prieto, Francisco B. Ortega · 2024 · Pediatric Obesity
Mycoplasma pneumoniae drives macrophage lipid uptake via GlpD-mediated oxidation, facilitating foam cell formation
Takeshi Yamamoto, Miki Okuno, Koichi Kuwano, Yoshitoshi Ogura · 2025 · International Journal of Medical Microbiology
Targeting the immune system towards novel therapeutic avenues to fight brain aging and neurodegeneration
Javier María Peralta Ramos, Denise Kviatcovsky, Michal Schwartz · 2022 · European Journal of Neuroscience
New Insights into Microglia as Therapeutic Targets in Alzheimer’s Disease
Deepa S. Mandlik, Satish K. Mandlik, Heena Bholaram Choudhary · 2023 · Current Drug Therapy
S100A9/Mrp14 Plays an Important Role in Ab Amyloidosis Enhancement
Fuyuki Kametani · 2014 · Journal of Neurology & Stroke
Extracellular Hsp90α Detoxifies β-Amyloid Fibrils Through an NRF2 and Autophagy Dependent Pathway
Ayesha Murshid, Benjamin J. Lang, Thiago J. Borges, Yuka Okusha, Sachin Doshi, Suraya Yasmine, Joanne Clark, Reeham Choudhury, Lay‐Hong Ang, Maya E. Woodbury et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Insulin-like growth factor-1 enhances β-amyloid protein clearance in HMC3 microglia via low-density lipoprotein receptor-related protein 1-mediated pathway
Hongsong Guo, Xiaoqian Peng, Xiao Chen Zhang, John Bosco Ruganzu, Xiangyuan Wu, Mingtao Zhao, Yang Pengbo, Shengfeng Ji, Weina Yang · 2026 · Experimental Cell Research
PD-1/PD-L1 signaling in neurological and psychiatric disorders: neuroimmune mechanisms and therapeutic potential
Xiangning Chen, Xingjun Wang, Chengwei Li, Kaiyue Shan, Lezhen Wang, Kenji Hashimoto, Kai Shao, Penghui Wei, Jian-jun Yang · 2026 · Brain Behavior and Immunity
Is Alzheimer's Associated Amyloid Beta an Innate Immune Protein
Ruth Kandel, Mitchell R. White, I-Ni Hseih, Kevan L. Hartshorn · 2016 · InTech eBooks
Macrophage Class A Scavenger Receptors – A Functional Perspective
Siamon Gordon, Matthew Wai Heng Chung, Scarlett L Harris, Fernando O. Martínez, Subhankar Mukhopadhyay · 2022 · Elsevier eBooks
RIP140 in Stress Response of the Brain
Yu‐Lung Lin, Yi-Wei Li, Li‐Na Wei · 2020 · Journal of Neurology and Neuromedicine
Genomics of Alzheimer’s disease
Roger N. Rosenberg, Doris Lambracht‐Washington, Gang Yu, Weiming Xia · 2020 · Elsevier eBooks
Therapeutic and immunomodulatory functions of the translocator protein in Alzheimer's disease
Lauren Hermes Fairley · 2022
Additional file 2 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
Mandana Hunter, Krista J. Spiller, Myrna A. Dominique, Xu, Hong, Francis W. Hunter, Terry Fang, Rebecca G. Canter, Roberts, Christopher J., Richard M. Ransohoff, John Q. Trojanowski et al. · 2021 · Figshare
Additional file 4 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
Mandana Hunter, Krista J. Spiller, Myrna A. Dominique, Xu, Hong, Francis W. Hunter, Terry Fang, Rebecca G. Canter, Roberts, Christopher J., Richard M. Ransohoff, John Q. Trojanowski et al. · 2021 · Figshare
Additional file 3 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
Mandana Hunter, Krista J. Spiller, Myrna A. Dominique, Xu, Hong, Francis W. Hunter, Terry Fang, Rebecca G. Canter, Roberts, Christopher J., Richard M. Ransohoff, John Q. Trojanowski et al. · 2021 · Figshare
Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages
Wulin Aerbajinai, Jianqiong Zhu, Kyung Chin, Griffin P. Rodgers · 2024 · Journal of Leukocyte Biology
Genomics of Alzheimer’s disease
Roger N. Rosenberg, Doris Lambracht‐Washington, Gang Yu, Weiming Xia · 2024 · Elsevier eBooks
Why Creating Transmissible Microbial Interferon Factories May Bring a Promise of a “Golden Era” in Future Human and Animal Health
Theodor-Nicolae Carp · 2025 · Preprints.org
Why Creating Transmissible Microbial Interferon Factories May Bring a Promise of a “Golden Era” in Future Human and Animal Health
Theodor-Nicolae Carp · 2025 · Preprints.org
Nonamyloid-beta active immunization for the treatment of Alzheimer’s disease
Olivia Triplett, Nicole Varda, Boris Decourt, Marwan Noel Sabbagh · 2025 · Expert Opinion on Investigational Drugs
Additional file 1 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
Mandana Hunter, Krista J. Spiller, Myrna A. Dominique, Xu, Hong, Francis W. Hunter, Terry Fang, Rebecca G. Canter, Roberts, Christopher J., Ransohoff, Richard M., John Q. Trojanowski et al. · 2021 · Figshare
Additional file 1 of Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice
Dorit Farfara, Meital Sooliman, Limor Avrahami, Tabitha Grace Royal, Shoshik Amram, Lea Rozenstein‐Tsalkovich, Dorit Trudler, Shani Blanga‐Kanfi, Hagit Eldar-Finkelman, Jens Pahnke et al. · 2023 · Figshare