Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

Fendt, Sarah-Maria, Bell, Eric L., Keibler, Mark A., Olenchock, Benjamin A., Mayers, Jared R., Wasylenko, Thomas M., Vokes, Natalie I., Guarente, Leonard +2 more·2013·Nature Communications

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  75. Review: can diet influence the selective advantage of mitochondrial DNA haplotypes?
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  80. Stable Isotope Tracer Analysis in Isolated Mitochondria from Mammalian Systems
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  82. Applying pathway engineering to enhance production of alpha-ketoglutarate in Yarrowia lipolytica
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  84. Hypoxic adaptation of mitochondria and its impact on tumor cell function
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