Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model
Wu, Zheng, Guo, Ziyuan, Gearing, Marla, Chen, Gong·2014·Nature Communications
Cited by (308)
Items 101–200 of 308
- Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer’s diseaseYue Wang, Zheng Wu, Yu-Ting Bai, Gang-Yi Wu, Gong Chen · 2017 · Molecular Neurodegeneration
- Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memoryLee, Vallent, MacKenzie, Georgina, Hooper, Andrew, Maguire, Jamie · 2016 · Hippocampus
- Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic PlasticityKai Wang, Weiming Sun, Linlin Zhang, Wei Guo, Jiachun Xu, Shuang Liu, Zhen Zhou, Yulian Zhang · 2018 · CNS & Neurological Disorders - Drug Targets
- GABAergic astrocytes in Alzheimer’s diseaseOlga Garaschuk, Alexei Verkhratsky · 2019 · Aging
- Metabolomics-Based Identification of Metabolic Dysfunction in FrailtyReyhan Westbrook, Cissy Zhang, Huanle Yang, Jing Tian, Shenghao Guo, Qian‐Li Xue, Jeremy D Walston, Anne Le, Peter M. Abadir · 2021 · The Journals of Gerontology Series A
- Dissociation of nNOS from PSD‐95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytesYu‐Hui Lin, Haiying Liang, Ke Xu, Huanyu Ni, Jian Ping Dong, Hui Xiao, Lei Chang, Hai‐Yin Wu, Fei Li, Dong‐Ya Zhu et al. · 2017 · The Journal of Pathology
- Altered Neurochemistry in Alzheimer’s Disease: Targeting Neurotransmitter Receptor Mechanisms and Therapeutic StrategySunpreet Kaur, G. DasGupta, Shamsher Singh · 2019 · Neurophysiology
- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer’s DiseaseArjun Thapa, Eva Y. Chi · 2015 · Advances in experimental medicine and biology
- Astrocytes and Adenosine A2A Receptors: Active Players in Alzheimer’s DiseaseCátia R. Lopes, Rodrigo Antunes Cunha, Paula M. Agostinho · 2021 · Frontiers in Neuroscience
- Γ-Aminobutyric acid in adult brain: an updateEwa Siucińska · 2019 · Behavioural Brain Research
- Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer diseaseOcéane Guillemaud, Kelly Ceyzériat, Thomas Saint-Georges, Karine Cambon, Fanny Petit, Lucile Ben Haim, María-Angeles Carrillo-de Sauvage, Martine Guillermier, Suéva Bernier, Anne‐Sophie Hérard et al. · 2019 · Neurobiology of Aging
- Astrocytic GABA Accumulation in Experimental Temporal Lobe EpilepsyJulia Müller, Aline Timmermann, Lukas Henning, Hendrik Müller, Christian Steinhäuser, Peter Bedner · 2020 · Frontiers in Neurology
- The S1PR2‐CCL2‐BDNF‐TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemiaYaiza M. Arenas, Tiziano Balzano, Gergana Mincheva, Marta Llansola, Vicente Felipo · 2022 · Neuropathology and Applied Neurobiology
- Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer’s diseaseGyujin Heo, Ying Xu, Erming Wang, Muhammad Ali, Hamilton Se‐Hwee Oh, Patricia Morán Losada, Federica Anastasi, Armand González Escalante, Raquel Puerta, Soomin Song et al. · 2025 · Nature Aging
- Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain functionStefanie Kickinger, Eva Hellsberg, Bente Frølund, Arne Schousboe, Gerhard Franz Ecker, Petrine Wellendorph · 2019 · Neuropharmacology
- Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathwayYaiza M. Arenas, Andrea Cabrera‐Pastor, Nora Juciute, Eloy Mora-Navarro, Vicente Felipo · 2020 · Journal of Neuroinflammation
- Positron emission tomography imaging of the γ-aminobutyric acid systemJan D. Andersson, David Matuskey, Sjoerd J. Finnema · 2018 · Neuroscience Letters
- Scaling Synapses in the Presence of HIVMatthew V. Green, Jonathan D. Raybuck, Xinwen Zhang, Mariah M. Wu, Stanley A. Thayer · 2018 · Neurochemical Research
- Label-free imaging and quantitative chemical analysis of Alzheimer’s disease brain samples with multimodal multiphoton nonlinear optical microspectroscopyJang Hyuk Lee, Dae Hwan Kim, Woo Keun Song, Myoung‐Kyu Oh, Do‐Kyeong Ko · 2015 · Journal of Biomedical Optics
- The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's diseaseYuanhong Tang, Yan Yan, Jian Mao, Junjun Ni, Hong Qing · 2023 · Ageing Research Reviews
- HIV gp120‐induced neuroinflammation potentiates NMDA receptors to overcome basal suppression of inhibitory synapses by p38 MAPKXinwen Zhang, Matthew V. Green, Stanley A. Thayer · 2018 · Journal of Neurochemistry
- Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s diseaseJulio Rodríguez-Lavado, Carlos Gallardo‐Garrido, Michael Mallea, Victor Bustos, Rodrigo Osorio, Martín Hödar-Salazar, Hery Chung, Ramiro Araya‐Maturana, Marcos Lorca, Carlos David Pessoa-Mahana et al. · 2020 · European Journal of Medicinal Chemistry
- Activity- and sleep-dependent regulation of tonic inhibition by Shisa7Kunwei Wu, Wenyan Han, Qingjun Tian, Yan Li, Wei Lü · 2021 · Cell Reports
- A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's diseaseBianca Brawek, Robert Chesters, Daniel Klement, Julia Müller, Chommanad Lerdkrai, Marina Hermes, Olga Garaschuk · 2017 · Neurobiology of Aging
- Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's DiseaseYanfang Li, Zhicai Chen, Yue Gao, Gaojie Pan, Hong-Hua Zheng, Yun-Wu Zhang, Hua-Xi Xu, Guo-Jun Bu, Hui Zheng · 2017 · Journal of Neuroscience
- Alpha-asarone Improves Cognitive Function of APP/PS1 Mice and Reducing Aβ42, P-tau and Neuroinflammation, and Promoting Neuron Survival in the HippocampusLili Zeng, Di Zhang, Qi Liu, Jian Zhang, Keman Mu, Xiaofeng Gao, Kun Zhang, Hui Li, Qiantao Wang, Yongxiang Zheng et al. · 2021 · Neuroscience
- Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMPAndrea Cabrera‐Pastor, Yaiza M. Arenas, Lucas Taoro‐González, Carmina Montoliu, Vicente Felipo · 2019 · Neuropharmacology
- Reactive Oxygen Species-mediated Loss of Phenotype of Parvalbumin Interneurons Contributes to Long-term Cognitive Impairments After Repeated Neonatal Ketamine ExposuresHui Zhang, Xiaoru Sun, Jing Wang, Zhenzhen Zhang, Hongting Zhao, Huihui Li, Mu‐Huo Ji, Kuan-yu Li, Jianjun Yang · 2016 · Neurotoxicity Research
- GAT3 selective substrate l -isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in miceMaria E. K. Lie, Emma K. Gowing, Nina B Johansen, Nils Ole Dalby, Louise Thiesen, Petrine Wellendorph, Andrew N. Clarkson · 2017 · Journal of Cerebral Blood Flow & Metabolism
- Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRIGuoshi Li, Li‐Ming Hsu, Ye Wu, Andrea Bozoki, Yen‐Yu Ian Shih, Pew‐Thian Yap · 2025 · Communications Medicine
- Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and StrokeMaria E. K. Lie, Anas Al-Khawaja, Maria Damgaard, Anne S. Haugaard, Arne Schousboe, Andrew N. Clarkson, Petrine Wellendorph · 2017 · Advances in neurobiology
- Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age‐dependent manner, normalizes GABA‐activated currents in the tg‐APPSwe mouse model of Alzheimer’s diseaseHayma Hammoud, Olga Netsyk, Atieh S. Tafreshiha, Sergiy V. Korol, Zhe Jin, Jin-Ping Li, Bryndis Birnir · 2021 · Acta Physiologica
- Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transportersAnna Pasieka, Dawid Panek, Jakub Jończyk, Justyna Godyń, Natalia Szałaj, Gniewomir Latacz, Julia Tabor, Eva Mezeiová, Fabien Chantegreil, José Dias et al. · 2021 · European Journal of Medicinal Chemistry
- Optogenetic manipulation of astrocytes from synapses to neuronal networks: A potential therapeutic strategy for neurodegenerative diseasesZhen Xie, Qinghu Yang, Da Feng Song, Zhenzhen Quan, Hong Qing · 2019 · Glia
- The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during AgingConnor M. Wander, Jui‐Heng Tseng, Sheng Song, Heba Al Housseiny, Dalton S. Tart, Aditi Ajit, Yen‐Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B. Meeker et al. · 2020 · iScience
- Effects of inhibiting astrocytes and BET/BRD4 chromatin reader on spatial memory and synaptic proteins in rats with Alzheimer’s diseaseRastin Nikkar, Aghil Esmaeili‐bandboni, Mahshid Badrikoohi, Parvin Babaei · 2022 · Metabolic Brain Disease
- HIV ‐1 Tat activates a RhoA signaling pathway to reduce NMDA ‐evoked calcium responses in hippocampal neurons via an actin‐dependent mechanismKelly A. Krogh, Elizabeth Lyddon, Stanley A. Thayer · 2014 · Journal of Neurochemistry
- Traumatic Brain Injury Broadly Affects GABAergic Signaling in Dentate Gyrus Granule CellsAlejandro Parga Becerra, Aric Flint Logsdon, William A. Banks, Christopher B. Ransom · 2021 · eNeuro
- Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7RPaula Beltran-Lobo, Matthew J. Reid, María Jiménez-Sánchez, Alexei Verkhratsky, Beatriz Gomez Perez‐Nievas, Wendy J. Noble · 2022 · Essays in Biochemistry
- Amyloid-Beta1-42 -Induced Increase in GABAergic Tonic Conductance in Mouse Hippocampal CA1 Pyramidal CellsBeatriz Calvo‐Flores Guzmán, SooHyun Kim, Bhavya Chawdhary, Katie Peppercorn, Warren Perry Tate, Henry John Waldvogel, Richard L. M. Faull, Johanna M. Montgomery, Andrea Kwakowsky · 2020 · Molecules
- Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 TeslaBeata R. Godlewska, S. R. Williams, Uzay E. Emir, Chi Chen, Ann L. Sharpley, Ana Jorge Gonçalves, Monique Ingrid Andersson, William T. Clarke, Brian Angus, Philip J. Cowen · 2021 · Psychopharmacology
- Aß Pathology and Neuron–Glia Interactions: A Synaptocentric ViewChristiaan F. M. Huffels, Jinte Middeldorp, Elly M. Hol · 2022 · Neurochemical Research
- Astrocyte-mediated metaplasticity in the hippocampus: Help or hindrance?Owen D. Jones · 2015 · Neuroscience
- Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult miceRaffaella Barbieri, Andrea Contestabile, Maria Grazia Ciardo, Nicola Rosario Forte, Antonella Marte, Pietro Baldelli, Fabio Benfenati, Franco Onofri · 2018 · Oncotarget
- Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer’s diseaseNing Li, Yang Li, Li-Juan Li, Ke Zhu, Yan Zheng, Xiaomin Wang · 2019 · Neural Regeneration Research
- Blocking Astrocytic GABA Restores Synaptic Plasticity in Prefrontal Cortex of Rat Model of DepressionIpsit Srivastava, Erika Vázquez‐Juárez, Lukas Henning, Marta Gómez‐Galán, Maria Lindskog · 2020 · Cells
- Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in HyperammonemiaYaiza M. Arenas, Mar Martinez‐García, Marta Llansola, Vicente Felipo · 2022 · International Journal of Molecular Sciences
- Astrocytic transporters in Alzheimer's diseaseUgbode, Chris, Hu, Yuhan, Whalley, Benjamin, Peers, Chris, Rattray, Marcus, Dallas, Mark L. · 2017 · Biochemical Journal
- GABA is a modulator, rather than a classical transmitter, in the medial nucleus of the trapezoid body–lateral superior olive sound localization circuitAlexander U. Fischer, Nicolas I. C. Müller, Thomas Deller, Domenico Del Turco, Jonas O. Fisch, Désirée Griesemer, Kathrin Kattler, Ayse Maraslioglu-Sperber, Vera Roemer, Matthew A. Xu‐Friedman et al. · 2019 · The Journal of Physiology
- Melatonin in Synaptic Impairments of Alzheimer’s DiseaseYan Shi, Ying‐Yan Fang, Yuping Wei, Qian Jiang, Peng Hui Zeng, Na Tang, Youming Lu, Qing Tian · 2018 · Journal of Alzheimer s Disease
- Biophysical Basis of Alpha Rhythm Disruption in Alzheimer’s DiseaseRohan Sharma, Suhita Nadkarni · 2020 · eNeuro
- An Astrocytic Influence on Impaired Tonic Inhibition in Hippocampal CA1 Pyramidal Neurons in a Mouse Model of Rett SyndromeQiping Dong, Jason Kim, Linh Nguyen, Qian Bu, Qiang Chang · 2020 · Journal of Neuroscience
- Alternative Targets to Fight Alzheimer’s Disease: Focus on AstrocytesMarta Valenza, Roberta Facchinetti, Giorgia Menegoni, Luca Steardo, Caterina Scuderi · 2021 · Biomolecules
- Using stable isotope tracing to unravel the metabolic components of neurodegeneration: Focus on neuron-glia metabolic interactionsEmil Winther Westi, Jens Velde Andersen, Blanca I. Aldana · 2023 · Neurobiology of Disease
- Epileptic Mechanisms Shared by Alzheimer’s Disease: Viewed via the Unique Lens of Genetic EpilepsyJing‐Qiong Kang · 2021 · International Journal of Molecular Sciences
- The GABA–Working Memory Relationship in Alzheimer’s DiseasePravat Kumar Mandal, Krity Kansara, Aroma Dabas · 2017 · Journal of Alzheimer s Disease Reports
- Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's DiseaseClaudia Salcedo, Antonie Wagner, Jens Velde Andersen, Kasper Tore Vinten, Helle S. Waagepetersen, Arne Schousboe, Kristine Freude, Blanca I. Aldana · 2021 · Neurochemical Research
- Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's diseaseArnold Salazar, Amanda M. Leisgang Osse, Andrew Adonay Ortiz, Andrew S. Murtishaw, Jefferson W. Kinney · 2020 · Neurobiology of Aging
- Pharmacology of GABA and Its ReceptorsSunpreet Kaur, Shamsher Singh, Anchal Arora, Parladh Ram, Sachin Kumar, Puneet Kumar, Sara Nidal Abed · 2020 · Springer eBooks
- Rollercoaster ride of kynurenines: steering the wheel towards neuroprotection in Alzheimer’s diseaseRadhika Sharma, Karan Razdan, Yashika Bansal, Anurag Kuhad · 2018 · Expert Opinion on Therapeutic Targets
- The Healthy and Diseased Retina Seen through Neuron–Glia InteractionsMatheus Heidemann Tempone, Vladimir Pedro Peralva Borges-Martins, Felipe Godinho Galvão César, Dio Pablo Alexandrino-Mattos, Camila Saggioro de Figueiredo, Ícaro Raony, Aline Araújo dos Santos, Aline Teixeira Duarte-Silva, Mariana Santana Dias, Hércules Rezende Freitas et al. · 2024 · International Journal of Molecular Sciences
- Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP / PS1 miceChristiaan F. M. Huffels, Lana M. Osborn, Lianne A. Hulshof, Lieneke Kooijman, Lukas Henning, Christian Steinhäuser, Elly M. Hol · 2022 · Glia
- Rethinking intellectual disability from neuro- to astro-pathology.Fernández-Blanco, Álvaro, Dierssen, Mara · 2020 · International Journal of Molecular Sciences
- Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in MiceCristina Torres‐López, María Isabel Cuartero, Alicia García‐Culebras, Juan de la Parra, María Encarnación Fernández-Valle, Marina Benito, Sandra Vázquez‐Reyes, Tania Jareño-Flores, Francisco Javier Castro-Millán, Olivia Hurtado et al. · 2023 · Stroke
- Alzheimer’s Disease Enhanced Tonic Inhibition is Correlated With Upregulated Astrocyte GABA Transporter-3/4 in a Knock-In APP Mouse ModelYousif Aldabbagh, Anam Islam, Weicong Zhang, Paul John Whiting, Afia B. Ali · 2022 · Frontiers in Pharmacology
- Role of GABAA receptors in EEG activity and spatial recognition memory in aged APP and PS1 double transgenic miceYu Fu, Liane Li, Yumei Wang, Guanghui Chu, Xiangyang Kong, Jianhong Wang · 2019 · Neurochemistry International
- Functional Characterization of Resting and Adenovirus-Induced Reactive Astrocytes in Three-Dimensional CultureJunsung Woo, Sun-Kyoung Im, Heejung Chun, Soon-Young Jung, Soo‐Jin Oh, Nakwon Choi, Changjoon Justin Lee, Eun‐Mi Hur · 2017 · Experimental Neurobiology
- Feedback adaptation of synaptic excitability via Glu:Na+ symport driven astrocytic GABA and Gln releaseLászló Héja, Ágnes Simon, Zsolt Mihály Szabó, Julianna Kardos · 2019 · Neuropharmacology
- The Evolution of AChE Inhibitors in Alzheimer's Disease: From Single‐Target to Multi‐Target LigandsNamrashee V. Mehta, Akshay Kapadia, Mihir Khambete, Arundhati Nachiket Abhyankar · 2025 · ChemBioChem
- Impaired Synaptic Plasticity Mechanisms in Alzheimer’s DiseaseRasoul Ebrahimi, Zahra Golzari, Mahsa Heidari‐Foroozan, Azin Khosravi, Samin Ghaheri Sharghi, Mobina Saleh, Shakiba Salarvandian, Khadijeh Esmaeilpour · 2025 · Metabolic Brain Disease
- Impaired Experience-Dependent Refinement of Place Cells in a Rat Model of Alzheimer’s DiseaseJohn I. Broussard, John B. Redell, Mark E. Maynard, Jing Zhao, Anthony Moore, Rachel W. Mills, Kimberly N. Hood, Erica L. Underwood, Badrinath Roysam, Pramod K. Dash · 2022 · Journal of Alzheimer s Disease
- Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's diseaseJovana Aranđelović, Anja Santrač, Bojan Batinić, Lidija Todorović, Vladimir Stevanović, V. V. N. Phani Babu Tiruveedhula, Dishary Sharmin, Farjana Rashid, Boban Stanojević, James Minton Cook et al. · 2022 · CNS Neuroscience & Therapeutics
- Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer’s disease miceHe‐Zhou Huang, Wen-Qing Ai, Na Wei, Ling‐Shuang Zhu, Zhiqiang Liu, Chao-Wen Zhou, Man‐Fei Deng, Wen-Tao Zhang, Jia-Chen Zhang, Chunqing Yang et al. · 2023 · Protein & Cell
- Baicalin and baicalein from Scutellaria baicalensis Georgi alleviate aberrant neuronal suppression mediated by GABA from reactive astrocytesJuyeong Cho, Eun‐Bin Hong, Young‐Sik Kim, Jungbin Song, Yeon Ha Ju, Hyun‐Jin Kim, Hyowon Lee, Hocheol Kim, Min‐Ho Nam · 2024 · CNS Neuroscience & Therapeutics
- Rhythmic astrocytic GABA production synchronizes neuronal circadian timekeeping in the suprachiasmatic nucleusNatalie Ness, Sandra Díaz-Clavero, Marieke MB Hoekstra, Marco Brancaccio · 2024 · The EMBO Journal
- Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout MiceQingwei Huo, Ming Chen, Quansheng He, Jiajia Zhang, Bo Li, Kai Jin, Xi Chen, Cheng Long, Li Yang · 2016 · Cerebral Cortex
- Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal DementiaJ. Terreros-Roncal, M. Flor-García, E. P. Moreno-Jiménez, Noemí Pallas-Bazarra, A. Rábano, N. Sah, H. van Praag, Damiana Giacomini, Alejandro F. Schinder, J. Avila et al. · 2019 · Journal of Neuroscience
- From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimers DiseaseJazmín Alarcón‐Espósito, Michael Mallea, Julio Rodríguez-Lavado · 2020 · Current Neuropharmacology
- Structure modeling of γ-aminobutyric acid transporters – Molecular basics of ligand selectivityKamil Łątka, Jakub Jończyk, Marek Bajda · 2020 · International Journal of Biological Macromolecules
- Enhanced GABAergic Tonic Inhibition Reduces Intrinsic Excitability of Hippocampal CA1 Pyramidal Cells in Experimental Autoimmune EncephalomyelitisLaura G. Kammel, Weizheng Wei, Shekib A. Jami, Rhonda R. Voskuhl, Thomas J. O’Dell · 2018 · Neuroscience
- Inhibition of a tonic inhibitory conductance in mouse hippocampal neurones by negative allosteric modulators of α5 subunit-containing γ-aminobutyric acid type A receptors: implications for treating cognitive deficitsMarc A. Manzo, Dian-Shi Wang, Winston W. Li, Arsène Pinguelo, M. Oana Popa, Shahin Khodaei, John R. Atack, Ruth A. Ross, Beverley Anne Orser · 2020 · British Journal of Anaesthesia
- Dynamic interactions between GABAergic and astrocytic networksAnnamaria Lia, Micaela Zonta, Linda Maria Requie, Giorgio Carmignoto · 2018 · Neuroscience Letters
- An α5 GABAA Receptor Inverse Agonist, α5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal CulturesChitra Vinnakota, Karan Govindpani, Warren Perry Tate, Katie Peppercorn, Praju Vikas Anekal, Henry John Waldvogel, Richard L. M. Faull, Andrea Kwakowsky · 2020 · International Journal of Molecular Sciences
- Gastrodin Attenuates Cognitive Deficits Induced by 3,3′-IminodipropionitrileXiaona Wang, Peng Li, Jingsheng Liu, Xunbo Jin, Lianjun Li, Dong Zhang, Peng Sun · 2016 · Neurochemical Research
- Space-Dependent Glia–Neuron Interplay in the Hippocampus of Transgenic Models of β-Amyloid DepositionDaniele Lana, Filippo Ugolini, Maria Grazia Giovannini · 2020 · International Journal of Molecular Sciences
- The Influence of the Gut Microbiota on Alzheimer's Disease: A Narrative ReviewJun-Ting Yin, Xiaowei Xu, Chen-Yang Jin, Xiaoying Yuan, Xugang Wang · 2023 · Journal of Integrative Neuroscience
- The 5×FAD mouse model of Alzheimer's diseaseCaroline Ismeurt, Patrizia Giannoni, Sylvie Claeysen · 2020 · Elsevier eBooks
- Regulation of GABAergic neurotransmission by purinergic receptors in brain physiology and diseaseGuilherme de Araujo Juvenal, Guilherme Shigueto Vilar Higa, Lucas Bonfim Marques, Thais T. Zampieri, Felipe José Costa Viana, Luiz R.G. Britto, Yong Cheng Tang, Péter Illés, Francesco Di Virgilio, Henning Ulrich et al. · 2024 · Purinergic Signalling
- Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's diseasePaula Zaręba, Kamil Łątka, Gabriela Mazur, Beata Gryzło, Anna Pasieka, Justyna Godyń, Dawid Panek, Anna Skrzypczak-Wiercioch, Georg C. Höfner, Gniewomir Latacz et al. · 2023 · European Journal of Medicinal Chemistry
- Decreased extrasynaptic δ‐GABA A receptors in PNN‐associated parvalbumin interneurons correlates with anxiety in APP and tau mouse models of Alzheimer's diseaseWeicong Zhang, Tiansheng Liu, Jialin Li, Jaijeet Singh, Andi Chan, Anam Islam, Alexandra L. Petrache, Yunan Peng, Kirsten Harvey, Afia B. Ali · 2024 · British Journal of Pharmacology
- Tonic GABAAConductance Favors Spike-Timing-Dependent over Theta-Burst-Induced Long-Term Potentiation in the HippocampusYulia Dembitskaya, Yu‐Wei Wu, Alexey V. Semyanov · 2020 · Journal of Neuroscience
- ONO-8590580, a Novel GABAA α5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves Cognitive Deficits in Preclinical ModelsSoichi Kawaharada, Miki Nakanishi, Nobuto Nakanishi, Keisuke Hazama, Masato Higashino, Tetsuya Yasuhiro, Arwel Lewis, Gary S. Clark, Mark S. Chambers, Scott A. Maidment et al. · 2018 · Journal of Pharmacology and Experimental Therapeutics
- Electroacupuncture Ameliorates Cognitive Impairment by Regulating γ-Amino Butyric Acidergic Interneurons in the Hippocampus of 5 Familial Alzheimer’s Disease MiceHongzhu Li, Lanfeng Lai, Xin Li, Runyi Wang, Xiaoling Fang, Nenggui Xu, Jiaying Zhao · 2023 · Neuromodulation Technology at the Neural Interface
- Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ 42 ExposureYanling Yin, Yuanyuan Zhao, Song Han, Nan Zhang, Hanyu Chen, Xiaomin Wang · 2017 · Journal of Alzheimer s Disease
- Astrocyte Reactivity in Alzheimer’s Disease: Therapeutic Opportunities to Promote RepairNazanin Mirzaei, Nicola Davis, Tsz Wing Chau, Magdalena Sastre · 2021 · Current Alzheimer Research
- Gliovascular alterations in sporadic and familial Alzheimer's disease: <scp><i>APOE3</i></scp> Christchurch homozygote glioprotectionHenao‐Restrepo, Julián, López‐Murillo, Carolina, Valderrama‐Carmona, Pablo, Orozco‐Santa, Natalia, Gomez, Johana, Gutiérrez‐Vargas, Johanna, Moraga, Renato, Toledo, Jorge, Littau, Jessica Lisa, Härtel, Steffen et al. · 2023 · Brain Pathology
- Vitamin D Reduces GABA-Positive Astrocytes in the 5xFAD Mouse Model of Alzheimer’s DiseaseJiseung Kang, Mincheol Park, Tae Kim · 2024 · Journal of Alzheimer's Disease
- Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptorsJin Jin, Chong-Lei Fu, Jing Xia, Heyi Luo, Xianglian Wang, Si Xuan Chen, Huanhuan Mao, Kai Yuan, Lin Lü, Wei Xiong et al. · 2024 · Molecular Psychiatry
- Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse modelsMinkyung Kang, Jihye Choi, Jeong Ho Han, Toshiyuki Araki, Soo-Whee Kim, Hyun-Hee Ryu, Min-Gyun Kim, Seoyeon Kim, Han-Byul Jang, Sun Yong Kim et al. · 2025 · Journal of Clinical Investigation
- Inhibition of GABA transporters fails to afford significant protection following focal cerebral ischemiaMaria E. K. Lie, Emma K. Gowing, Rasmus P. Clausen, Petrine Wellendorph, Andrew N. Clarkson · 2017 · Journal of Cerebral Blood Flow & Metabolism