Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model

Wu, Zheng, Guo, Ziyuan, Gearing, Marla, Chen, Gong·2014·Nature Communications

Cited by (308)

Items 101–200 of 308

  1. Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer’s disease
    Yue Wang, Zheng Wu, Yu-Ting Bai, Gang-Yi Wu, Gong Chen · 2017 · Molecular Neurodegeneration
  2. Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory
    Lee, Vallent, MacKenzie, Georgina, Hooper, Andrew, Maguire, Jamie · 2016 · Hippocampus
  3. Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic Plasticity
    Kai Wang, Weiming Sun, Linlin Zhang, Wei Guo, Jiachun Xu, Shuang Liu, Zhen Zhou, Yulian Zhang · 2018 · CNS & Neurological Disorders - Drug Targets
  4. GABAergic astrocytes in Alzheimer’s disease
    Olga Garaschuk, Alexei Verkhratsky · 2019 · Aging
  5. Metabolomics-Based Identification of Metabolic Dysfunction in Frailty
    Reyhan Westbrook, Cissy Zhang, Huanle Yang, Jing Tian, Shenghao Guo, Qian‐Li Xue, Jeremy D Walston, Anne Le, Peter M. Abadir · 2021 · The Journals of Gerontology Series A
  6. Dissociation of nNOS from PSD‐95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytes
    Yu‐Hui Lin, Haiying Liang, Ke Xu, Huanyu Ni, Jian Ping Dong, Hui Xiao, Lei Chang, Hai‐Yin Wu, Fei Li, Dong‐Ya Zhu et al. · 2017 · The Journal of Pathology
  7. Altered Neurochemistry in Alzheimer’s Disease: Targeting Neurotransmitter Receptor Mechanisms and Therapeutic Strategy
    Sunpreet Kaur, G. DasGupta, Shamsher Singh · 2019 · Neurophysiology
  8. Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer’s Disease
    Arjun Thapa, Eva Y. Chi · 2015 · Advances in experimental medicine and biology
  9. Astrocytes and Adenosine A2A Receptors: Active Players in Alzheimer’s Disease
    Cátia R. Lopes, Rodrigo Antunes Cunha, Paula M. Agostinho · 2021 · Frontiers in Neuroscience
  10. Γ-Aminobutyric acid in adult brain: an update
    Ewa Siucińska · 2019 · Behavioural Brain Research
  11. Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease
    Océane Guillemaud, Kelly Ceyzériat, Thomas Saint-Georges, Karine Cambon, Fanny Petit, Lucile Ben Haim, María-Angeles Carrillo-de Sauvage, Martine Guillermier, Suéva Bernier, Anne‐Sophie Hérard et al. · 2019 · Neurobiology of Aging
  12. Astrocytic GABA Accumulation in Experimental Temporal Lobe Epilepsy
    Julia Müller, Aline Timmermann, Lukas Henning, Hendrik Müller, Christian Steinhäuser, Peter Bedner · 2020 · Frontiers in Neurology
  13. The S1PR2‐CCL2‐BDNF‐TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia
    Yaiza M. Arenas, Tiziano Balzano, Gergana Mincheva, Marta Llansola, Vicente Felipo · 2022 · Neuropathology and Applied Neurobiology
  14. Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer’s disease
    Gyujin Heo, Ying Xu, Erming Wang, Muhammad Ali, Hamilton Se‐Hwee Oh, Patricia Morán Losada, Federica Anastasi, Armand González Escalante, Raquel Puerta, Soomin Song et al. · 2025 · Nature Aging
  15. Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain function
    Stefanie Kickinger, Eva Hellsberg, Bente Frølund, Arne Schousboe, Gerhard Franz Ecker, Petrine Wellendorph · 2019 · Neuropharmacology
  16. Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway
    Yaiza M. Arenas, Andrea Cabrera‐Pastor, Nora Juciute, Eloy Mora-Navarro, Vicente Felipo · 2020 · Journal of Neuroinflammation
  17. Positron emission tomography imaging of the γ-aminobutyric acid system
    Jan D. Andersson, David Matuskey, Sjoerd J. Finnema · 2018 · Neuroscience Letters
  18. Scaling Synapses in the Presence of HIV
    Matthew V. Green, Jonathan D. Raybuck, Xinwen Zhang, Mariah M. Wu, Stanley A. Thayer · 2018 · Neurochemical Research
  19. Label-free imaging and quantitative chemical analysis of Alzheimer’s disease brain samples with multimodal multiphoton nonlinear optical microspectroscopy
    Jang Hyuk Lee, Dae Hwan Kim, Woo Keun Song, Myoung‐Kyu Oh, Do‐Kyeong Ko · 2015 · Journal of Biomedical Optics
  20. The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease
    Yuanhong Tang, Yan Yan, Jian Mao, Junjun Ni, Hong Qing · 2023 · Ageing Research Reviews
  21. HIV gp120‐induced neuroinflammation potentiates NMDA receptors to overcome basal suppression of inhibitory synapses by p38 MAPK
    Xinwen Zhang, Matthew V. Green, Stanley A. Thayer · 2018 · Journal of Neurochemistry
  22. Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
    Julio Rodríguez-Lavado, Carlos Gallardo‐Garrido, Michael Mallea, Victor Bustos, Rodrigo Osorio, Martín Hödar-Salazar, Hery Chung, Ramiro Araya‐Maturana, Marcos Lorca, Carlos David Pessoa-Mahana et al. · 2020 · European Journal of Medicinal Chemistry
  23. Activity- and sleep-dependent regulation of tonic inhibition by Shisa7
    Kunwei Wu, Wenyan Han, Qingjun Tian, Yan Li, Wei Lü · 2021 · Cell Reports
  24. A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease
    Bianca Brawek, Robert Chesters, Daniel Klement, Julia Müller, Chommanad Lerdkrai, Marina Hermes, Olga Garaschuk · 2017 · Neurobiology of Aging
  25. Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's Disease
    Yanfang Li, Zhicai Chen, Yue Gao, Gaojie Pan, Hong-Hua Zheng, Yun-Wu Zhang, Hua-Xi Xu, Guo-Jun Bu, Hui Zheng · 2017 · Journal of Neuroscience
  26. Alpha-asarone Improves Cognitive Function of APP/PS1 Mice and Reducing Aβ42, P-tau and Neuroinflammation, and Promoting Neuron Survival in the Hippocampus
    Lili Zeng, Di Zhang, Qi Liu, Jian Zhang, Keman Mu, Xiaofeng Gao, Kun Zhang, Hui Li, Qiantao Wang, Yongxiang Zheng et al. · 2021 · Neuroscience
  27. Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP
    Andrea Cabrera‐Pastor, Yaiza M. Arenas, Lucas Taoro‐González, Carmina Montoliu, Vicente Felipo · 2019 · Neuropharmacology
  28. Reactive Oxygen Species-mediated Loss of Phenotype of Parvalbumin Interneurons Contributes to Long-term Cognitive Impairments After Repeated Neonatal Ketamine Exposures
    Hui Zhang, Xiaoru Sun, Jing Wang, Zhenzhen Zhang, Hongting Zhao, Huihui Li, Mu‐Huo Ji, Kuan-yu Li, Jianjun Yang · 2016 · Neurotoxicity Research
  29. GAT3 selective substrate l -isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice
    Maria E. K. Lie, Emma K. Gowing, Nina B Johansen, Nils Ole Dalby, Louise Thiesen, Petrine Wellendorph, Andrew N. Clarkson · 2017 · Journal of Cerebral Blood Flow & Metabolism
  30. Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRI
    Guoshi Li, Li‐Ming Hsu, Ye Wu, Andrea Bozoki, Yen‐Yu Ian Shih, Pew‐Thian Yap · 2025 · Communications Medicine
  31. Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke
    Maria E. K. Lie, Anas Al-Khawaja, Maria Damgaard, Anne S. Haugaard, Arne Schousboe, Andrew N. Clarkson, Petrine Wellendorph · 2017 · Advances in neurobiology
  32. Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age‐dependent manner, normalizes GABA‐activated currents in the tg‐APPSwe mouse model of Alzheimer’s disease
    Hayma Hammoud, Olga Netsyk, Atieh S. Tafreshiha, Sergiy V. Korol, Zhe Jin, Jin-Ping Li, Bryndis Birnir · 2021 · Acta Physiologica
  33. Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters
    Anna Pasieka, Dawid Panek, Jakub Jończyk, Justyna Godyń, Natalia Szałaj, Gniewomir Latacz, Julia Tabor, Eva Mezeiová, Fabien Chantegreil, José Dias et al. · 2021 · European Journal of Medicinal Chemistry
  34. Optogenetic manipulation of astrocytes from synapses to neuronal networks: A potential therapeutic strategy for neurodegenerative diseases
    Zhen Xie, Qinghu Yang, Da Feng Song, Zhenzhen Quan, Hong Qing · 2019 · Glia
  35. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging
    Connor M. Wander, Jui‐Heng Tseng, Sheng Song, Heba Al Housseiny, Dalton S. Tart, Aditi Ajit, Yen‐Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B. Meeker et al. · 2020 · iScience
  36. Effects of inhibiting astrocytes and BET/BRD4 chromatin reader on spatial memory and synaptic proteins in rats with Alzheimer’s disease
    Rastin Nikkar, Aghil Esmaeili‐bandboni, Mahshid Badrikoohi, Parvin Babaei · 2022 · Metabolic Brain Disease
  37. HIV ‐1 Tat activates a RhoA signaling pathway to reduce NMDA ‐evoked calcium responses in hippocampal neurons via an actin‐dependent mechanism
    Kelly A. Krogh, Elizabeth Lyddon, Stanley A. Thayer · 2014 · Journal of Neurochemistry
  38. Traumatic Brain Injury Broadly Affects GABAergic Signaling in Dentate Gyrus Granule Cells
    Alejandro Parga Becerra, Aric Flint Logsdon, William A. Banks, Christopher B. Ransom · 2021 · eNeuro
  39. Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7R
    Paula Beltran-Lobo, Matthew J. Reid, María Jiménez-Sánchez, Alexei Verkhratsky, Beatriz Gomez Perez‐Nievas, Wendy J. Noble · 2022 · Essays in Biochemistry
  40. Amyloid-Beta1-42 -Induced Increase in GABAergic Tonic Conductance in Mouse Hippocampal CA1 Pyramidal Cells
    Beatriz Calvo‐Flores Guzmán, SooHyun Kim, Bhavya Chawdhary, Katie Peppercorn, Warren Perry Tate, Henry John Waldvogel, Richard L. M. Faull, Johanna M. Montgomery, Andrea Kwakowsky · 2020 · Molecules
  41. Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla
    Beata R. Godlewska, S. R. Williams, Uzay E. Emir, Chi Chen, Ann L. Sharpley, Ana Jorge Gonçalves, Monique Ingrid Andersson, William T. Clarke, Brian Angus, Philip J. Cowen · 2021 · Psychopharmacology
  42. Aß Pathology and Neuron–Glia Interactions: A Synaptocentric View
    Christiaan F. M. Huffels, Jinte Middeldorp, Elly M. Hol · 2022 · Neurochemical Research
  43. Astrocyte-mediated metaplasticity in the hippocampus: Help or hindrance?
    Owen D. Jones · 2015 · Neuroscience
  44. Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice
    Raffaella Barbieri, Andrea Contestabile, Maria Grazia Ciardo, Nicola Rosario Forte, Antonella Marte, Pietro Baldelli, Fabio Benfenati, Franco Onofri · 2018 · Oncotarget
  45. Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer’s disease
    Ning Li, Yang Li, Li-Juan Li, Ke Zhu, Yan Zheng, Xiaomin Wang · 2019 · Neural Regeneration Research
  46. Blocking Astrocytic GABA Restores Synaptic Plasticity in Prefrontal Cortex of Rat Model of Depression
    Ipsit Srivastava, Erika Vázquez‐Juárez, Lukas Henning, Marta Gómez‐Galán, Maria Lindskog · 2020 · Cells
  47. Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia
    Yaiza M. Arenas, Mar Martinez‐García, Marta Llansola, Vicente Felipo · 2022 · International Journal of Molecular Sciences
  48. Astrocytic transporters in Alzheimer's disease
    Ugbode, Chris, Hu, Yuhan, Whalley, Benjamin, Peers, Chris, Rattray, Marcus, Dallas, Mark L. · 2017 · Biochemical Journal
  49. GABA is a modulator, rather than a classical transmitter, in the medial nucleus of the trapezoid body–lateral superior olive sound localization circuit
    Alexander U. Fischer, Nicolas I. C. Müller, Thomas Deller, Domenico Del Turco, Jonas O. Fisch, Désirée Griesemer, Kathrin Kattler, Ayse Maraslioglu-Sperber, Vera Roemer, Matthew A. Xu‐Friedman et al. · 2019 · The Journal of Physiology
  50. Melatonin in Synaptic Impairments of Alzheimer’s Disease
    Yan Shi, Ying‐Yan Fang, Yuping Wei, Qian Jiang, Peng Hui Zeng, Na Tang, Youming Lu, Qing Tian · 2018 · Journal of Alzheimer s Disease
  51. Biophysical Basis of Alpha Rhythm Disruption in Alzheimer’s Disease
    Rohan Sharma, Suhita Nadkarni · 2020 · eNeuro
  52. An Astrocytic Influence on Impaired Tonic Inhibition in Hippocampal CA1 Pyramidal Neurons in a Mouse Model of Rett Syndrome
    Qiping Dong, Jason Kim, Linh Nguyen, Qian Bu, Qiang Chang · 2020 · Journal of Neuroscience
  53. Alternative Targets to Fight Alzheimer’s Disease: Focus on Astrocytes
    Marta Valenza, Roberta Facchinetti, Giorgia Menegoni, Luca Steardo, Caterina Scuderi · 2021 · Biomolecules
  54. Using stable isotope tracing to unravel the metabolic components of neurodegeneration: Focus on neuron-glia metabolic interactions
    Emil Winther Westi, Jens Velde Andersen, Blanca I. Aldana · 2023 · Neurobiology of Disease
  55. Epileptic Mechanisms Shared by Alzheimer’s Disease: Viewed via the Unique Lens of Genetic Epilepsy
    Jing‐Qiong Kang · 2021 · International Journal of Molecular Sciences
  56. The GABA–Working Memory Relationship in Alzheimer’s Disease
    Pravat Kumar Mandal, Krity Kansara, Aroma Dabas · 2017 · Journal of Alzheimer s Disease Reports
  57. Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease
    Claudia Salcedo, Antonie Wagner, Jens Velde Andersen, Kasper Tore Vinten, Helle S. Waagepetersen, Arne Schousboe, Kristine Freude, Blanca I. Aldana · 2021 · Neurochemical Research
  58. Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease
    Arnold Salazar, Amanda M. Leisgang Osse, Andrew Adonay Ortiz, Andrew S. Murtishaw, Jefferson W. Kinney · 2020 · Neurobiology of Aging
  59. Pharmacology of GABA and Its Receptors
    Sunpreet Kaur, Shamsher Singh, Anchal Arora, Parladh Ram, Sachin Kumar, Puneet Kumar, Sara Nidal Abed · 2020 · Springer eBooks
  60. Rollercoaster ride of kynurenines: steering the wheel towards neuroprotection in Alzheimer’s disease
    Radhika Sharma, Karan Razdan, Yashika Bansal, Anurag Kuhad · 2018 · Expert Opinion on Therapeutic Targets
  61. The Healthy and Diseased Retina Seen through Neuron–Glia Interactions
    Matheus Heidemann Tempone, Vladimir Pedro Peralva Borges-Martins, Felipe Godinho Galvão César, Dio Pablo Alexandrino-Mattos, Camila Saggioro de Figueiredo, Ícaro Raony, Aline Araújo dos Santos, Aline Teixeira Duarte-Silva, Mariana Santana Dias, Hércules Rezende Freitas et al. · 2024 · International Journal of Molecular Sciences
  62. Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP / PS1 mice
    Christiaan F. M. Huffels, Lana M. Osborn, Lianne A. Hulshof, Lieneke Kooijman, Lukas Henning, Christian Steinhäuser, Elly M. Hol · 2022 · Glia
  63. Rethinking intellectual disability from neuro- to astro-pathology.
    Fernández-Blanco, Álvaro, Dierssen, Mara · 2020 · International Journal of Molecular Sciences
  64. Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in Mice
    Cristina Torres‐López, María Isabel Cuartero, Alicia García‐Culebras, Juan de la Parra, María Encarnación Fernández-Valle, Marina Benito, Sandra Vázquez‐Reyes, Tania Jareño-Flores, Francisco Javier Castro-Millán, Olivia Hurtado et al. · 2023 · Stroke
  65. Alzheimer’s Disease Enhanced Tonic Inhibition is Correlated With Upregulated Astrocyte GABA Transporter-3/4 in a Knock-In APP Mouse Model
    Yousif Aldabbagh, Anam Islam, Weicong Zhang, Paul John Whiting, Afia B. Ali · 2022 · Frontiers in Pharmacology
  66. Role of GABAA receptors in EEG activity and spatial recognition memory in aged APP and PS1 double transgenic mice
    Yu Fu, Liane Li, Yumei Wang, Guanghui Chu, Xiangyang Kong, Jianhong Wang · 2019 · Neurochemistry International
  67. Functional Characterization of Resting and Adenovirus-Induced Reactive Astrocytes in Three-Dimensional Culture
    Junsung Woo, Sun-Kyoung Im, Heejung Chun, Soon-Young Jung, Soo‐Jin Oh, Nakwon Choi, Changjoon Justin Lee, Eun‐Mi Hur · 2017 · Experimental Neurobiology
  68. Feedback adaptation of synaptic excitability via Glu:Na+ symport driven astrocytic GABA and Gln release
    László Héja, Ágnes Simon, Zsolt Mihály Szabó, Julianna Kardos · 2019 · Neuropharmacology
  69. The Evolution of AChE Inhibitors in Alzheimer's Disease: From Single‐Target to Multi‐Target Ligands
    Namrashee V. Mehta, Akshay Kapadia, Mihir Khambete, Arundhati Nachiket Abhyankar · 2025 · ChemBioChem
  70. Impaired Synaptic Plasticity Mechanisms in Alzheimer’s Disease
    Rasoul Ebrahimi, Zahra Golzari, Mahsa Heidari‐Foroozan, Azin Khosravi, Samin Ghaheri Sharghi, Mobina Saleh, Shakiba Salarvandian, Khadijeh Esmaeilpour · 2025 · Metabolic Brain Disease
  71. Impaired Experience-Dependent Refinement of Place Cells in a Rat Model of Alzheimer’s Disease
    John I. Broussard, John B. Redell, Mark E. Maynard, Jing Zhao, Anthony Moore, Rachel W. Mills, Kimberly N. Hood, Erica L. Underwood, Badrinath Roysam, Pramod K. Dash · 2022 · Journal of Alzheimer s Disease
  72. Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
    Jovana Aranđelović, Anja Santrač, Bojan Batinić, Lidija Todorović, Vladimir Stevanović, V. V. N. Phani Babu Tiruveedhula, Dishary Sharmin, Farjana Rashid, Boban Stanojević, James Minton Cook et al. · 2022 · CNS Neuroscience & Therapeutics
  73. Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer’s disease mice
    He‐Zhou Huang, Wen-Qing Ai, Na Wei, Ling‐Shuang Zhu, Zhiqiang Liu, Chao-Wen Zhou, Man‐Fei Deng, Wen-Tao Zhang, Jia-Chen Zhang, Chunqing Yang et al. · 2023 · Protein & Cell
  74. Baicalin and baicalein from Scutellaria baicalensis Georgi alleviate aberrant neuronal suppression mediated by GABA from reactive astrocytes
    Juyeong Cho, Eun‐Bin Hong, Young‐Sik Kim, Jungbin Song, Yeon Ha Ju, Hyun‐Jin Kim, Hyowon Lee, Hocheol Kim, Min‐Ho Nam · 2024 · CNS Neuroscience & Therapeutics
  75. Rhythmic astrocytic GABA production synchronizes neuronal circadian timekeeping in the suprachiasmatic nucleus
    Natalie Ness, Sandra Díaz-Clavero, Marieke MB Hoekstra, Marco Brancaccio · 2024 · The EMBO Journal
  76. Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout Mice
    Qingwei Huo, Ming Chen, Quansheng He, Jiajia Zhang, Bo Li, Kai Jin, Xi Chen, Cheng Long, Li Yang · 2016 · Cerebral Cortex
  77. Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia
    J. Terreros-Roncal, M. Flor-García, E. P. Moreno-Jiménez, Noemí Pallas-Bazarra, A. Rábano, N. Sah, H. van Praag, Damiana Giacomini, Alejandro F. Schinder, J. Avila et al. · 2019 · Journal of Neuroscience
  78. From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimers Disease
    Jazmín Alarcón‐Espósito, Michael Mallea, Julio Rodríguez-Lavado · 2020 · Current Neuropharmacology
  79. Structure modeling of γ-aminobutyric acid transporters – Molecular basics of ligand selectivity
    Kamil Łątka, Jakub Jończyk, Marek Bajda · 2020 · International Journal of Biological Macromolecules
  80. Enhanced GABAergic Tonic Inhibition Reduces Intrinsic Excitability of Hippocampal CA1 Pyramidal Cells in Experimental Autoimmune Encephalomyelitis
    Laura G. Kammel, Weizheng Wei, Shekib A. Jami, Rhonda R. Voskuhl, Thomas J. O’Dell · 2018 · Neuroscience
  81. Inhibition of a tonic inhibitory conductance in mouse hippocampal neurones by negative allosteric modulators of α5 subunit-containing γ-aminobutyric acid type A receptors: implications for treating cognitive deficits
    Marc A. Manzo, Dian-Shi Wang, Winston W. Li, Arsène Pinguelo, M. Oana Popa, Shahin Khodaei, John R. Atack, Ruth A. Ross, Beverley Anne Orser · 2020 · British Journal of Anaesthesia
  82. Dynamic interactions between GABAergic and astrocytic networks
    Annamaria Lia, Micaela Zonta, Linda Maria Requie, Giorgio Carmignoto · 2018 · Neuroscience Letters
  83. An α5 GABAA Receptor Inverse Agonist, α5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures
    Chitra Vinnakota, Karan Govindpani, Warren Perry Tate, Katie Peppercorn, Praju Vikas Anekal, Henry John Waldvogel, Richard L. M. Faull, Andrea Kwakowsky · 2020 · International Journal of Molecular Sciences
  84. Gastrodin Attenuates Cognitive Deficits Induced by 3,3′-Iminodipropionitrile
    Xiaona Wang, Peng Li, Jingsheng Liu, Xunbo Jin, Lianjun Li, Dong Zhang, Peng Sun · 2016 · Neurochemical Research
  85. Space-Dependent Glia–Neuron Interplay in the Hippocampus of Transgenic Models of β-Amyloid Deposition
    Daniele Lana, Filippo Ugolini, Maria Grazia Giovannini · 2020 · International Journal of Molecular Sciences
  86. The Influence of the Gut Microbiota on Alzheimer's Disease: A Narrative Review
    Jun-Ting Yin, Xiaowei Xu, Chen-Yang Jin, Xiaoying Yuan, Xugang Wang · 2023 · Journal of Integrative Neuroscience
  87. The 5×FAD mouse model of Alzheimer's disease
    Caroline Ismeurt, Patrizia Giannoni, Sylvie Claeysen · 2020 · Elsevier eBooks
  88. Regulation of GABAergic neurotransmission by purinergic receptors in brain physiology and disease
    Guilherme de Araujo Juvenal, Guilherme Shigueto Vilar Higa, Lucas Bonfim Marques, Thais T. Zampieri, Felipe José Costa Viana, Luiz R.G. Britto, Yong Cheng Tang, Péter Illés, Francesco Di Virgilio, Henning Ulrich et al. · 2024 · Purinergic Signalling
  89. Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease
    Paula Zaręba, Kamil Łątka, Gabriela Mazur, Beata Gryzło, Anna Pasieka, Justyna Godyń, Dawid Panek, Anna Skrzypczak-Wiercioch, Georg C. Höfner, Gniewomir Latacz et al. · 2023 · European Journal of Medicinal Chemistry
  90. Decreased extrasynaptic δ‐GABA A receptors in PNN‐associated parvalbumin interneurons correlates with anxiety in APP and tau mouse models of Alzheimer's disease
    Weicong Zhang, Tiansheng Liu, Jialin Li, Jaijeet Singh, Andi Chan, Anam Islam, Alexandra L. Petrache, Yunan Peng, Kirsten Harvey, Afia B. Ali · 2024 · British Journal of Pharmacology
  91. Tonic GABAAConductance Favors Spike-Timing-Dependent over Theta-Burst-Induced Long-Term Potentiation in the Hippocampus
    Yulia Dembitskaya, Yu‐Wei Wu, Alexey V. Semyanov · 2020 · Journal of Neuroscience
  92. ONO-8590580, a Novel GABAA α5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves Cognitive Deficits in Preclinical Models
    Soichi Kawaharada, Miki Nakanishi, Nobuto Nakanishi, Keisuke Hazama, Masato Higashino, Tetsuya Yasuhiro, Arwel Lewis, Gary S. Clark, Mark S. Chambers, Scott A. Maidment et al. · 2018 · Journal of Pharmacology and Experimental Therapeutics
  93. Electroacupuncture Ameliorates Cognitive Impairment by Regulating γ-Amino Butyric Acidergic Interneurons in the Hippocampus of 5 Familial Alzheimer’s Disease Mice
    Hongzhu Li, Lanfeng Lai, Xin Li, Runyi Wang, Xiaoling Fang, Nenggui Xu, Jiaying Zhao · 2023 · Neuromodulation Technology at the Neural Interface
  94. Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ 42 Exposure
    Yanling Yin, Yuanyuan Zhao, Song Han, Nan Zhang, Hanyu Chen, Xiaomin Wang · 2017 · Journal of Alzheimer s Disease
  95. Astrocyte Reactivity in Alzheimer’s Disease: Therapeutic Opportunities to Promote Repair
    Nazanin Mirzaei, Nicola Davis, Tsz Wing Chau, Magdalena Sastre · 2021 · Current Alzheimer Research
  96. Gliovascular alterations in sporadic and familial Alzheimer's disease: <scp><i>APOE3</i></scp> Christchurch homozygote glioprotection
    Henao‐Restrepo, Julián, López‐Murillo, Carolina, Valderrama‐Carmona, Pablo, Orozco‐Santa, Natalia, Gomez, Johana, Gutiérrez‐Vargas, Johanna, Moraga, Renato, Toledo, Jorge, Littau, Jessica Lisa, Härtel, Steffen et al. · 2023 · Brain Pathology
  97. Vitamin D Reduces GABA-Positive Astrocytes in the 5xFAD Mouse Model of Alzheimer’s Disease
    Jiseung Kang, Mincheol Park, Tae Kim · 2024 · Journal of Alzheimer's Disease
  98. Cannabidiol ameliorates cognitive decline in 5×FAD mouse model of Alzheimer’s disease through potentiating the function of extrasynaptic glycine receptors
    Jin Jin, Chong-Lei Fu, Jing Xia, Heyi Luo, Xianglian Wang, Si Xuan Chen, Huanhuan Mao, Kai Yuan, Lin Lü, Wei Xiong et al. · 2024 · Molecular Psychiatry
  99. Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models
    Minkyung Kang, Jihye Choi, Jeong Ho Han, Toshiyuki Araki, Soo-Whee Kim, Hyun-Hee Ryu, Min-Gyun Kim, Seoyeon Kim, Han-Byul Jang, Sun Yong Kim et al. · 2025 · Journal of Clinical Investigation
  100. Inhibition of GABA transporters fails to afford significant protection following focal cerebral ischemia
    Maria E. K. Lie, Emma K. Gowing, Rasmus P. Clausen, Petrine Wellendorph, Andrew N. Clarkson · 2017 · Journal of Cerebral Blood Flow & Metabolism