Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells

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Items 101–200 of 219

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11. Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
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12. Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21
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14. An Interplay of S-Nitrosylation and Metal Ion Binding for Astrocytic S100B Protein
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18. Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy
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20. Generation of Urine-Derived Induced Pluripotent Stem Cells and Cerebral Organoids for Modeling Down Syndrome
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26. Triple play of DYRK1A kinase in cortical progenitor cells of Trisomy 21
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28. Surface-Enhanced Raman Scattering Nanoendoscope for Quantification of a Protein Released under Physiological Stimulation in Brain Tissue
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29. The potential of induced pluripotent stem cells in models of neurological disorders: implications on future therapy
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31. Induced Pluripotent Stem Cells: Global Research Trends
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32. From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome
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33. Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells
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34. Mechanical stabilization of proteolytically degradable polyethylene glycol dimethacrylate hydrogels through peptide interaction
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35. Rag2−/− accelerates lipofuscin accumulation in the brain: Implications for human stem cell brain transplantation studies
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36. Contribution of Human Pluripotent Stem Cell-Based Models to Drug Discovery for Neurological Disorders
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37. Concise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem Cells
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39. Molecular mechanisms that change synapse number
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40. Neural lineage differentiation of human pluripotent stem cells: Advances in disease modeling
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41. Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model
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42. Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells
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43. Advances in Recapitulating Alzheimer’s Disease Phenotypes Using Human Induced Pluripotent Stem Cell-Based In Vitro Models
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44. Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer's Disease
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45. Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome
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46. Single-Nucleus Profiling Identifies Accelerated Oligodendrocyte Precursor Cell Senescence in a Mouse Model of Down Syndrome
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48. Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
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51. Generation of iPSC-based human-mouse microglial brain chimeras to study senescence of human microglia
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64. Activity of Human-Specific Interlaminar Astrocytes in a Chimeric Mouse Model of Fragile X Syndrome
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69. Human-Mouse Chimeric Brain Models to Study Human Glial-Neuronal and Macroglial-Microglial Interactions
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70. Trisomy 21-driven metabolite alterations are linked to cellular injuries in Down syndrome
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75. Complement pathway dysregulation and astrocyte alterations in Down syndrome: evidence from postmortem brain tissue and iPSC-derived astrocytes
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76. Understanding perspectives and research trends in Down syndrome neuropathogenesis: A bibliometric analysis
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78. Molecular Mechanism Underlying Abnormal Differentiation of Neural Progenitor Cells in the Developing Down Syndrome Brain
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79. FOXP1 and ARID3A Collaborate to Activate Transcription of Core Embryonic Stem Cell Factors in Activated B - Cell Diffuse Large B cell Lymphoma
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84. The restoration of REST inhibits reactivity of Down syndrome iPSC-derived astrocytes
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85. Down syndrome and Alzheimer's disease: Oxidative stress in the neurodegenerative process
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89. Complement system alteration in iPSC-derived astrocytes from individuals with Down syndrome
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94. Modeling Down Syndrome Neurodevelopment with Dosage Compensation
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