Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells

Chen, Chen, Jiang, Peng, Xue, Haipeng, Peterson, Suzanne E., Tran, Ha T., McCann, Anna E., Parast, Mana M., Li, Shenglan +5 more·2014·Nature Communications

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  7. Realizing the potential of exploiting human IPSCs and their derivatives in research of Down syndrome
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  8. Human Models of Down Syndrome
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  9. Down Syndrome: Progress in Defining Pathogenesis and Treatments for Neurodevelopmental Deficits and Alzheimer’s Disease
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  10. Trisomy 21 Disrupts Thyroid Hormones Signaling During Human iPSC-Derived Neural Differentiation In Vitro
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  12. Additional file 2 of Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria
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  13. Additional file 3 of Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria
    Cheng, Xiao-Yu, Sangita Biswas, Li, Juan, Mao, Cheng-Jie, Chechneva, Olga, Chen, Jing, Kai Li, Li, Jiao, Zhang, Jin-Ru, Liu, Chun-Feng et al. · 2020 · Figshare
  14. Additional file 1 of Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria
    Cheng, Xiao-Yu, Sangita Biswas, Li, Juan, Mao, Cheng-Jie, Chechneva, Olga, Chen, Jing, Li, Kai, Li, Jiao, Zhang, Jin-Ru, Liu, Chun-Feng et al. · 2020 · Figshare
  15. Additional file 4 of Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria
    Cheng, Xiao-Yu, Sangita Biswas, Li, Juan, Mao, Cheng-Jie, Chechneva, Olga, Chen, Jing, Kai Li, Li, Jiao, Zhang, Jin-Ru, Liu, Chun-Feng et al. · 2020 · Figshare
  16. Contribution of proprioceptors in the mesencephalic trigeminal nucleus and their surrounding astrocytes to acidic saline-induced chronic jaw muscle pain in rodents
    Masaharu Yamada, Dorly Verdier, Arlette Kolta · 2026 · Frontiers in Cellular Neuroscience
  17. Role of astrocytic signaling in synapse function : implications for neurodevelopmental disorders
    Bruna Rubino · 2020
  18. Aberrant chromatin remodeling influences human neural cell fate change in Trisomy 21
    Jenny A. Klein, Suraj Upadhya, Anna J. Nathanson, Dana Silvian, Eric F. Zaniewski, Robert Morris, Wilhelm Haas, Lindy E. Barrett · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  19. XIST as a potential chromosome therapy for autosomal trisomy syndromes
    Adriana M. Tavares Gomes, Wen‐Hann Tan · 2026 · Translational Science of Rare Diseases