A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Cited by (384)

Items 201–300 of 384

1. SARS-CoV-2 Doggybone DNA Vaccine Produces Cross-Variant Neutralizing Antibodies and Is Protective in a COVID-19 Animal Model
   Eric M. Mucker, Rebecca L. Brocato, Lucia M. Principe, Robert K. Kim, Xiankun Zeng, Jeffrey Michael Smith, Steven A. Kwilas, Sung‐Won Kim, Helen Horton, Lisa J. Caproni et al. · 2022 · Vaccines
2. Precision vaccine design targeting the prefusion state of viral glycoproteins: advances in structural vaccinology
   Reetesh Kumar, Somnath Maji, Savitri Tiwari, J. P. Misra, Jyoti Gupta, Naveen Kumar, Rohan Gupta, Niraj Kumar Jha · 2025 · Biochemical Pharmacology
3. Respiratory syncytial virus: health burden, disease prevention, and treatment—recent progress and lessons learned
   Harald Brüssow · 2025 · microLife
4. DNA vaccine encoding central conserved region of G protein induces Th1 predominant immune response and protection from RSV infection in mice
   Ying Hua, Yue-Ying Jiao, Yao Ma, Xiang-Lei Peng, Yuan-Hui Fu, Yan-Peng Zheng, Tao Hong, Jinsheng He · 2016 · Immunology Letters
5. Evolution of protection after maternal immunization for respiratory syncytial virus in cotton rats
   Jorge C. G. Blanco, Lori M. Cullen, Arash Kamali, Fatoumata Y. D. Sylla, Marina S. Boukhvalova, Trudy G. Morrison · 2021 · PLoS Pathogens
6. The E484K Substitution in a SARS-CoV-2 Spike Protein Subunit Vaccine Resulted in Limited Cross-Reactive Neutralizing Antibody Responses in Mice
   Longbo Hu, Yuhua Xu, Liping Wu, Jin Feng, Lu Zhang, Yongjie Tang, Xiang Zhao, Runming Mai, Liyun Chen, Lingling Mei et al. · 2022 · Viruses
7. Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants
   Nidhi Mittal, Sahil Kumar, Raju S Rajmani, Randhir Singh, Céline Lemoine, Virginie Jakob, Sowrabha BJ, Nayana Jagannath, Madhuraj Bhat, Debajyoti Chakraborty et al. · 2023 · npj Vaccines
8. Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein
   Judith G. Alamares-Sapuay, Michael Kishko, Charles Lai, Mark Parrington, Simon Delagrave, Richard L. Herbert, Ashley Castens, Joanna Swerczek, Cindy Luongo, Lijuan Yang et al. · 2024 · PLoS ONE
9. Highly scalable prefusion-stabilized RSV F vaccine with enhanced immunogenicity and robust protection
   Qiong-lian Huang, Qingyun Lang, Yao Li, Fengjie Wang, Xiaonan Han, Ling Luo, Xiaomin Duan, Xuerong Cao, Yue Wang, Yu Bai et al. · 2025 · Nature Communications
10. Protection of chicks from Newcastle disease by combined vaccination with a plasmid DNA and the pre-fusion protein of the virulent genotype VII of Newcastle disease virus
    Junfeng Sun, Zongxi Han, Ran Zhao, Hui Ai, Linna Chen, Le Li, Shengwang Liu · 2020 · Vaccine
11. Intranasal vaccination with a recombinant protein CTA1-DD-RBF protects mice against hRSV infection
    Hai Li, Hu Ren, Yan Zhang, Lei Cao, Wenbo Xu · 2021 · Scientific Reports
12. Monoclonal antibody based in vitro potency assay as a predictor of antigenic integrity and in vivo immunogenicity of a Respiratory Syncytial Virus post-fusion F-protein based vaccine
    Matieyendou Didier Djagbare, Yu Li, Arun Parupudi, Jenny Sun, Melissa L. Coughlin, Benjamin S. Rush, Gautam Sanyal · 2018 · Vaccine
13. The Immune Correlates of Orthohantavirus Vaccine
    Joon‐Yong Bae, Jin Il Kim, Mee Sook Park, Gee Eun Lee, Heedo Park, Ki‐Joon Song, Man‐Seong Park · 2021 · Vaccines
14. A Phase 1/2a Study Evaluating Safety and Immunogenicity of Ad26.RSV.preF in RSV-seronegative Toddlers Aged 12–24 Months
    Joanne Marie Langley, Terry M. Nolan, Mika Rämet, Peter Richmond, Nelson Augusto Rosário Filho, Wouter Haazen, Sara P H van den Berg, Kristi L. Williams, Arangassery Rosemary Bastian, Edmund V Ekoka Omoruyi et al. · 2024 · Open Forum Infectious Diseases
15. RSVpreF vaccination in pregnancy: a meta-analysis of maternal-fetal safety and infant efficacy
    Greg J. Marchand, Ahmed T. Massoud, Ahmed Taha Abdelsattar, Peter Andrew McCullough · 2024 · Obstetrics & Gynecology Science
16. Broad-spectrum coronavirus vaccines: integrated strategies to combat viral diversity
    Qian He, Yi Zhang, Zhihao Fu, Xiao Ma, Zhenglun Liang · 2025 · Expert Review of Vaccines
17. Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Its Implications for Prophylactic and Therapeutic Pharmaceuticals
    Xiaowen Liang, Yue Yin, Yuanlong Lin, Shiman Chen, Qi Qian, Jing Yuan, Liuqing Yang, Yang Yang · 2025 · MedComm
18. The Optimal Concentration of Formaldehyde is Key to Stabilizing the Pre-Fusion Conformation of Respiratory Syncytial Virus Fusion Protein
    Wei Zhang, Lu-Jing Zhang, Lu-Ting Zhan, Min Zhao, Guanghua Wu, Jun-Yu Si, Li Chen, Xue Mei Lin, Yong-Peng Sun, Min Lin et al. · 2019 · Viruses
19. Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen
    Maarten Swart, Harmjan Kuipers, Fin J. Milder, Mandy A. C. Jongeneelen, Tina Ritschel, Jeroen T. B. M. Tolboom, Leacky K. Muchene, Joan E. M. van der Lubbe, Ana Izquierdo Gil, Daniel Veldman et al. · 2023 · npj Vaccines
20. Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface
    Xiao Xiao, Zhiyun Wen, Qing Chen, Jennifer M. Shipman, James C. Kostas, John C. Reid, Christopher Warren, Aimin Tang, Bin Luo, Gregory T. O’Donnell et al. · 2023 · Journal of Virology
21. Non-glycosylated G protein with CpG ODN provides robust protection against respiratory syncytial virus without inducing eosinophilia
    Eigo Kawahara, Takehiko Shibata, Toshiro Hirai, Yasuo Yoshioka · 2023 · Frontiers in Immunology
22. Comparisons of Antibody Populations in Different Pre-Fusion F VLP-Immunized Cotton Rat Dams and Their Offspring
    Lori M. Cullen, Marina S. Boukhvalova, Jorge C. G. Blanco, Trudy G. Morrison · 2020 · Vaccines
23. Combinatorial immune refocusing within the influenza hemagglutinin head elicits cross-neutralizing antibody responses
    Annie M. Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael Watson, John C. Kraft, Minh Nguyet Pham, Miklós Guttman, Kelly K. Lee et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
24. Proscan: a structure-based proline design web server
    Nathaniel R. Felbinger, Helder Veras Ribeiro Filho, Brian G. Pierce · 2024 · Nucleic Acids Research
25. Self-amplifying mRNA vaccines protect elderly BALB/c mice against a lethal respiratory syncytial virus infection
    Lulu Zuo, Qixing Liu, Ke Zhang, Lu Zhao, Siyu Lin, Yong Dai, Yun Sun, Yingwen Li, Pingping Zhang, Huyan Shen et al. · 2024 · Molecular Therapy
26. DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection
    Yiling Yang, Ruoke Wang, Fenglin Guo, Tian Zhao, Yuqing Lei, Qianqian Yang, Yige Zeng, Ziqing Yang, Tatchapon Ajavavarakula, Ruijie Tan et al. · 2024 · npj Vaccines
27. Highly Effective mRNA-LNP Vaccine Against Respiratory Syncytial Virus (RSV) in Multiple Models
    Huarong Bai, Xueliang Yu, Yue Gao, Qin Li, Baigang Wen, Rongkuan Hu · 2025 · Vaccines
28. Improved mRNA-based RSV vaccine with PreF forming enveloped virus-like particles
    Pengdi Chai, Yi Shi, Xiaoyan Li, Mengyao Yang, Xiafei Liu, Mei Liu, Junjie Yu, Xia Yin, Dongwei Li, Ke Li et al. · 2025 · npj Vaccines
29. Prefusion-stabilized Hantaan virus glycoprotein nucleic acid vaccine elicits potent neutralizing antibody responses via germinal center activation
    Wei Ye, Yamei Dang, Yuan Wang, Qiqi Yang, Hui Zhang, Chuantao Ye, Jing Wei, Jiawei Pei, Xuemin Pei, Du Jiang et al. · 2026 · Nature Communications
30. SARS-CoV-2 S Glycoprotein Stabilization Strategies
    Borys Pedenko, Guidenn Sulbarán, Delphine Guilligay, Grégory Effantin, Winfríed Weissenhorn · 2023 · Viruses
31. Age-Stratified Seroprevalence of Respiratory Syncytial Virus: Analysis Using Prefusion F and G Protein Antibodies
    Eliel Nham, A-Yeung Jang, Hakjun Hyun, Jin Gu Yoon, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim, Ki Bum Ahn, Hyun Jung Ji, Ho Seong Seo et al. · 2024 · Vaccines
32. Systematic computer-aided disulfide design as a general strategy to stabilize prefusion class I fusion proteins
    Karen J. Gonzalez, Kevin C. Yim, Jorge C. G. Blanco, Marina S. Boukhvalova, Eva‐Maria Strauch · 2024 · Frontiers in Immunology
33. An mRNA-Based Respiratory Syncytial Virus Vaccine Elicits Strong Neutralizing Antibody Responses and Protects Rodents Without Vaccine-Associated Enhanced Respiratory Disease
    Jianglong Li, Haiyan Long, Shaoyi Chen, Zhendong Zhang, Shuang Li, Qi Liu, Jun Liu, Jiaru Cai, Liping Luo, Yucai Peng · 2025 · Vaccines
34. An Optimized FI-RSV Vaccine Effectively Protects Cotton Rats and BALB/c Mice without Causing Enhanced Respiratory Disease
    Min Lin, Wei Zhang, Yifan Yin, Jun-Yu Si, Lu-Jing Zhang, Li Chen, Xue Mei Lin, Ying-Bin Wang, Jun Zhang, Zizheng Zheng et al. · 2022 · Viruses
35. Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase
    Ruipeng Lei, Timothy J.C. Tan, Andrea Hernandez Garcia, Yiquan Wang, Meghan V. Diefenbacher, Chuyun Teo, Gopika Gopan, Zahra Tavakoli Dargani, Qi Wen Teo, Claire S. Graham et al. · 2022 · Nature Communications
36. On the irrationality of rational design of an HIV vaccine in light of protein intrinsic disorder
    Vladimir Nikolaevich Uversky · 2021 · Archives of Virology
37. In silico virtual screening of lead compounds for major antigenic sites in respiratory syncytial virus fusion protein
    Shilu Mathew, Sara Taleb, Ali Hussein Eid, Asmaa A. Al Thani, Hadi Mohamad Yassine · 2021 · Emergent Materials
38. The Cumulative Variations of Respiratory Syncytial Virus Fusion Protein (F) in Ten Consecutive Years in China
    Fengjie Wang, Mingli Jiang, Zhenzhi Han, Yan‐Peng Xu, Yu Sun, Runan Zhu, Dongmei Chen, Qi Guo, Yutong Zhou, Yao Yao et al. · 2024 · Infectious Disease Reports
39. Mucosal vaccines with STING-agonist liposomal formulations inhibit RSV (respiratory syncytial virus) replication in cotton rats
    K M Samiur Rahman Sefat, Rohan SUDHIR Kulkarni, Jason Trinh, Ankita Leekha, Monish Kumar, Haoran Wu, Trevor McBride, Letisha O. Aideyan, Vasanthi Avadhanula, Pedro A. Piedra et al. · 2025 · Vaccine
40. Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification
    Yi-Zong Lee, Yi-Nan Zhang, Maddy L. Newby, Garrett Ward, Keegan Braz Gomes, Sarah Auclair, Connor DesRoberts, Joel D. Allen, Andrew B. Ward, Robyn L. Stanfield et al. · 2025 · Nature Communications
41. A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein
    Alexandra A. Abu-Shmais, Luqiang Guo, Ahmed Magdy Khalil, Sabina E W Leonard, Rose J. Miller, Alexis K. Janke, Matthew J. Vukovich, Lindsay E Bass, Yukthi P. Suresh, Scott A. Rush et al. · 2026 · Cell Reports Medicine
42. RSV vaccine development: advances and fusion protein-focused strategies
    Wang Xu, Revansiddha H. Katte, Maolin Lu · 2026 · Frontiers in Immunology
43. Stabilization of the H5 clade 2.3.4.4b hemagglutinin improves vaccine-elicited neutralizing antibody responses in mice
    Annie M. Dosey, Bernadeta Dadonaite, Rebecca A. Gillespie, Elizabeth M. Leaf, Matthew J. Vukovich, Jackson McGowan, Emily Grey, Hiromi Muramatsu, Rachel H. J. Jun, Norbert Pardi et al. · 2026 · Science Translational Medicine
44. Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses
    Ignacio Fernández, François Bontems, Delphine Brun, Youna Coquin, Casper A. Goverde, Bruno E. Correia, Antoine Gessain A, Florence Buseyne, Felix Augusto Rey, Marija Backović · 2024 · Science Advances
45. Intranasal Inoculation of Cationic Crosslinked Carbon Dots‐Adjuvanted Respiratory Syncytial Virus F Subunit Vaccine Elicits Mucosal and Systemic Humoral and Cellular Immunity
    Lei Hong, Aqu Alu, H. J. Yang, Cai He, Jie Shi, Weiqi Hong, Dandan Peng, Yu Zhang, Jian Liu, Furong Qin et al. · 2025 · MedComm
46. Immunogenicity, safety, and tolerability of a β-glucan-CpG-adjuvanted respiratory syncytial virus vaccine in Japanese healthy participants aged 60 to 80 years: A phase 2, randomized, double-blind, dose-finding study
    Tetsuo Nakayama, Makoto Iwanami, Sachiko Sakakibara, Ryuta Mukasa, Aisaku Ota, Kei Furihata, Yuko Honda, Ken J. Ishii · 2025 · Human Vaccines & Immunotherapeutics
47. Unveiling the Spectrum of Respiratory Syncytial Virus Disease in Adults: From Community to Hospital
    Koos Korsten, Matthijs R. A. Welkers, Thijs J. W. van de Laar, Alex Wagemakers, Peter van Hengel, Peter C. Wever, Eva Kolwijck · 2025 · Influenza and Other Respiratory Viruses
48. Nanobody-based combination vaccine using licensed protein nanoparticles protects animals against respiratory and viral infections
    Tingting Li, Wenhui Xue, Sibo Zhang, Hong Wang, Miaolin Lan, Limin Zhang, Min Lin, Ming Zhou, Ying Dong, Yarong Zeng et al. · 2025 · Nature Biomedical Engineering
49. Correlative outcomes of maternal immunization against RSV in cotton rats
    Jorge C. G. Blanco, Lori M. Cullen, Arash Kamali, Fatoumata Y. D. Sylla, Zenab Chinmoun, Marina S. Boukhvalova, Trudy G. Morrison · 2022 · Human Vaccines & Immunotherapeutics
50. The Central Conserved Peptides of Respiratory Syncytial Virus G Protein Enhance the Immune Response to the RSV F Protein in an Adenovirus Vector Vaccine Candidate
    Pengdi Chai, Yi Shi, Junjie Yu, Xiafei Liu, Dongwei Li, Jinsong Li, Lili Li, Dan-di Li, Zhaojun Duan · 2024 · Vaccines
51. A novel C-terminal modification method enhanced the yield of human papillomavirus L1 or chimeric L1-L2 virus-like particles in the baculovirus system
    Mingrao Ma, Baicheng Xia, Zhirong Wang, Yaru Hao, Ting Zhang, Xuemei Xu · 2023 · Frontiers in Bioengineering and Biotechnology
52. The rise of mRNA therapeutic vaccines
    Jinlu Du, Ziling Fan, Jiangming Huang, Zhengyuan Li, Haitao Hu, Yanxia Li · 2025 · RSC Pharmaceutics
53. Hydrophobic residue substitutions enhance the stability and in vivo immunogenicity of respiratory syncytial virus fusion protein
    Qiao‐Yun Song, Haixia Yang, Haoyue Zhu, Yun Hu, Wenling Shen, Huifeng Cheng, Jialiao Cai, Manlan Qiu, Yueyue Li, Yaolan Li et al. · 2025 · Journal of Virology
54. RSV: Available Prophylactic Options and Vaccines in Clinical Trials
    Debra T. Linfield, Fariba Rezaee · 2019 · IntechOpen eBooks
55. Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study
    Max Beugeling, Katie Amssoms, Freek Cox, Ben De Clerck, Ellen R. Van Gulck, Jeroen A. Verwoerd, Guenter Kraus, Dirk Roymans, Lieven Baert, Henderik Willem Frijlink et al. · 2019 · Pharmaceutics
56. The Design of Vaccines Based on the Shielding of Antigenic Site Ø of a Respiratory Syncytial Virus Fusion Protein Immunogen
    Steven J. Frey, Chad Varner, Ammar Arsiwala, Michael G. Currier, Martin L. Moore, Ravi S. Kane · 2020 · Advanced Healthcare Materials
57. Current status and future trends of vaccine development against viral infection and disease
    Hongpeng Wang, Zhi-Gang Wang, Shulin Liu · 2021 · New Journal of Chemistry
58. Novel Strategies for Developing Next-Generation Vaccines to Combat Infectious Viral Diseases
    Fangfeng Yuan, Martin H. Bluth · 2025 · Vaccines
59. Advances in the structure-based design of protein vaccines for respiratory infectious diseases
    Xiaotian Tie, Jiaxuan Li, Hao Wu, Ruiqi Weng, Yanjun Zhang, Jianhua Li, Keda Chen · 2025 · Computational and Structural Biotechnology Journal
60. Antibody cocktails based on the occupationally acquired immunity of pediatricians neutralize and confer protection against RSV and hMPV
    Hui Zhai, WenXiang Yu, Jinyue Wang, Jie V. Deng, Siyu Lei, Teng Zhou, Yixin Li, Kaijun Xu, Mengyang Ma, Rui Feng et al. · 2026 · Science Translational Medicine
61. Fight fire with fire: the need for a vaccine based on intrinsic disorder and structural flexibility
    Vladimir Nikolaevich Uversky · 2022 · Exploration of Immunology
62. Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses
    Sathya N. Thulasi Raman, Adrian Zetner, Anwar M. Hashem, Devina Patel, Jianguo Wu, Caroline Gravel, Jun Gao, Wanyue Zhang, Annabelle Pfeifle, Levi A. Tamming et al. · 2023 · Emerging Microbes & Infections
63. Design of hepadnavirus core protein-based chimeric virus-like particles carrying epitopes from respiratory syncytial virus
    Shuai Shao, Xuefeng Zhang, Jun Wei Hou, Sen Yang, Zi Bo Han, Hai Lan Wu, Fang Tang, Xin Yu Li, Ze Hua Lei, Zi Xin Zhao et al. · 2024 · npj Vaccines
64. Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies
    Nicole V. Johnson, Revina C. van Scherpenzeel, Mark J. G. Bakkers, Ajit R. Ramamohan, Daan van Overveld, Lam Le, Johannes P. M. Langedijk, Joost A. Kolkman, Jason S. McLellan · 2024 · Nature Communications
65. Induction of neutralizing antibody responses by AAV5-based vaccine for respiratory syncytial virus in mice
    Guangxu Ma, Zeping Xu, Chinyu Li, Feng Zhou, Branda T. Hu, Junwei Guo, Changwen Ke, Liqing Chen, Guilin Zhang, Hungyan Lau et al. · 2024 · Frontiers in Immunology
66. Influence of antigen conformation and mode of presentation on the antibody and protective responses against human respiratory syncytial virus: relevance for vaccine development
    José Antonio Melero · 2016 · Expert Review of Vaccines
67. Human respiratory syncytial virus F protein expressed in Pichia pastoris or Escherichia coli induces protective immunity without inducing enhanced respiratory disease in mice
    Hai Li, Lei Cao, Yan Zhang, Hu Ren, Peibei Zhao, Wenbo Xu · 2020 · Archives of Virology
68. Long-Lasting Protection Induced by a Polyanhydride Nanovaccine against Respiratory Syncytial Virus in an Outbred Mouse Model
    Laura M. Stephens, Kathleen A. Ross, Jason S. McLellan, Balaji Narasimhan, Steven M. Varga · 2022 · Journal of Virology
69. Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins
    Albert S. Song, Taylor A. Poor, Luciano A. Abriata, Theodore S. Jardetzky, Matteo Dal Peraro, Robert A. Lamb · 2016 · Proceedings of the National Academy of Sciences
70. A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers
    Yi-Zong Lee, Jerome Han, Yi-Nan Zhang, Garrett Ward, Keegan Braz Gomes, Sarah Auclair, Robyn L. Stanfield, Linling He, Ian A. Wilson, Jiang Zhu · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
71. Respiratory Syncytial Virus Fusion Activity Syncytia Assay
    Kearstin L. Edmonds, Rebecca Dutch · 2025 · Methods in molecular biology
72. Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA forms
    Jing Li, Xuehui Ma, Zepeng Xu, Wenjing Guo, Ruchao Peng, Yuqin Zhang, Yumin Meng, Jianrui Zhao, Qiyue Wang, Shuang Li et al. · 2025 · EBioMedicine
73. Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 Variants
    Ritika Khatri, Hilal Ahmad Parray, Gazala Siddiqui, Adarsh Kumar Chiranjivi, Sneha Raj, Rachel Kaul, Vikas Maithil, Sweety Samal, Shubbir Ahmed · 2022 · The Protein Journal
74. Pneumoviruses: Respiratory Syncytial Virus and Human Metapneumovirus
    Jarrod J. Mousa, John V. Williams, James E. Crowe · 2022 · Springer eBooks
75. From setbacks to success: lessons from the journey of RSV vaccine development
    Victor M. Cnossen, Rogier P. van Leeuwen, Natalie I Mazur, Charlotte Vernhes, Wouter ten Voorde, Jacobus Burggraaf, Saco J. de Visser, Meta Roestenberg, Ingrid M. C. Kamerling · 2024 · Therapeutic Advances in Vaccines and Immunotherapy
76. Adenovectored RSV prefusion glycoprotein + soluble glycoprotein combination immunization establishes persistent opsonophagocytic antibody response through IgG3
    Xin Tong, Ross Blanc, Deniz Cizmeci, Hadar Malca, Jaewon Kang, Christy A. Comeaux, Benoît Callendret, Arangassery Rosemary Bastian, Mehak Zahoor Khan, Galit Alter et al. · 2025 · Frontiers in Immunology
77. Immunofocusing design of a fusion glycoprotein monomer vaccine for respiratory syncytial virus
    Qianqian Li, Zhiming Li, Jiamin Chen, Qiuju He, Hongjian Xiao, Haiwei Li, Huan Li, Heng Zhang, Yaoyun Yang, Rong Bi et al. · 2025 · Molecular Therapy
78. Modeling Human Respiratory Syncytial Virus (RSV) Infection: Recent Contributions and Future Directions Using the Calf Model of Bovine RSV Disease
    Fabián E. Díaz, Jodi L. McGill · 2023 · The Journal of Immunology
79. Immunogenicity of a recombinant plant-produced respiratory syncytial virus F subunit vaccine in mice
    Nuttapat Pisuttinusart, Balamurugan Shanmugaraj, Chanya Srisaowakarn, Chutitorn Ketloy, Eakachai Prompetchara, Arunee Thitithanyanont, Waranyoo Phoolcharoen · 2023 · Biotechnology Reports
80. Respiratory Syncytial Virus Vaccination in the Adult Pulmonary Patient
    Ajay Sheshadri, Scott E. Evans · 2024 · CHEST Journal
81. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches
    Jarek Juraszek, Fin J. Milder, Xiaodi Yu, Sven Blokland, Daan van Overveld, Pravien D. Abeywickrema, Sem Tamara, Sujata Pandit Sharma, Lucy Rutten, Mark J. G. Bakkers et al. · 2024 · PNAS Nexus
82. Prevention of respiratory syncytial virus from 1991 to 2024: a systematic review and bibliometrics analysis
    Xue Li, Xia Yu, Zixi Du, Ling Zhang, Yeyuan Wang, Ying Wu, Yonghong Lin, Yulei He · 2024 · Translational Pediatrics
83. Group IIC self-splicing intron-derived novel circular RNA vaccine elicits superior immune response against RSV
    Zeyun Sun, Lirong Lu, Lijie Liu, Ruoxu Liang, Qiqi Zhang, Zhining Liu, Jiahao An, Qian Liu, Qingxin Wu, Shuai Wei et al. · 2025 · Frontiers in Immunology
84. The impact of high-resolution structural data on stemming the COVID-19 pandemic
    R. Cox, Richard K. Plemper · 2021 · Current Opinion in Virology
85. HRSV prefusion-F protein with Adju-Phos adjuvant induces long-lasting Th2-biased immunity in mice
    Hai Li, Hu Ren, Yangzi Zhou, Yan Zhang, Lei Cao, Wenbo Xu · 2022 · PLoS ONE
86. CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline
    Reda Rawi, Chen‐Hsiang Shen, Peter D. Kwong, Gwo‐Yu Chuang · 2018 · Journal of Chemical Information and Modeling
87. The Burden of Respiratory Syncytial Virus Infection in the Young
    Bernhard Resch · 2019 · IntechOpen eBooks
88. Respiratory Syncytial Virus-like Particles Consisting of M, G and Prefusion F
    Pramila Walpita, Lisa M Johns · 2016 · SM Tropical Medicine Journal
89. Generation of antigen-specific paired chain antibody sequences using large language models
    Perry T. Wasdin, Nicole V. Johnson, Alexis K. Janke, Sofia Held, Toma M. Marinov, Gwen Jordaan, Léna Vandenabeele, Fani Pantouli, Rebecca A. Gillespie, Matthew J. Vukovich et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
90. The Interplay of Furin Cleavage and D614G in Modulating SARS-CoV-2 Spike Protein Dynamics
    Sophie R. Shoemaker, Megan Luo, Kim-Marie A. Dam, John E. Pak, Magnus A. G. Hoffmann, Susan Marqusee · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
91. Ad26.RSV.preF completely protects calves from severe respiratory disease induced by bovine RSV challenge
    Leslie van der Fits, Rineke de Jong, Karin Dijkman, Marjolein Heemskerk-van der Meer, Lisanne Tettero, Judith Bonsing, Sophie van Oort, Jan Serroyen, Marianke van Schie, Norbert Stockhofe-Zurwieden et al. · 2024 · npj Vaccines
92. Developing an eVLP mRNA vaccine for respiratory syncytial virus with enhanced pre-fusion targeting humoral responses
    Lei Sun, Mengting Huang, Simin Feng, Wei Zhang, Yun Quan, Ruyi Chen, Yupeng Yang, Haidong Xu, Wansheng Li, Qianyu Pan et al. · 2025 · Journal of Virology
93. Production of Clinical-Grade SARS-CoV-2 Spike Ferritin Nanoparticle Protein Immunogen by Transient Transfection
    Agnes Hajduczki, William C. Chang, Rafael A. De La Barrera, James F. Wood, Wei-hung Chen, Elizabeth J. Martinez, Jaime L. Jensen, Rajeshwer Singh Sankhala, Clayton Smith, Alexander Anderson et al. · 2025 · Vaccines
94. Virus-like Particle Vaccines Containing RSV Fusion Protein Cleavage Mutations Are Immunogenic and Protective in Cotton Rats With a Prime Dose
    Hye Suk Hwang, Young‐Man Kwon, Ki‐Hye Kim, Young‐Tae Lee, Eun‐Ju Ko, Arun Meas, Sang‐Moo Kang · 2025 · Immune Network
95. Spatial Segregation Within Dissolving Microneedle Patches Overcomes Antigenic Interference and Enables Potent Bivalent Influenza–RSV Vaccination in Mice
    Feng Fan, Yehong Wu, Hongzhe Lin, Xin Zhang, Limei Wang, Yue He, Shijie Zhang, M Y Zhang, Gan Zhao, Rong Xiang et al. · 2025 · Vaccines
96. A point-mutated Ag85B antigen improves recombinant bacterial expression and protects mice from aerosol M. tuberculosis challenge
    Wen-Ling Hsu, Yang Jiao, Matthew G. Hvasta, Kristina N. Tran, Brennen T. Troyer, Wei‐Chiao Huang, Brian A. Kuhlman, Andrés Obregón‐Henao, Jonathan F. Lovell · 2026 · Vaccine
97. Isolation and characterization of broadly-neutralizing anti-HCMV-gB antibodies from human donors using a prefusion-stabilized HCMV gB variant
    Maria Krasilnikov, Yu-Hsin Wan, Ellen M. White, Beatriz Gálvez-Martínez, Mohammad Karimian Shamsabadi, Nicholas T. Aldridge, Bibhav Poudel, Adrian W. Sperl, Andrew McGuire, Ekaterina E. Zheleznova Heldwein · 2026 · PLoS Pathogens
98. The Development of Global Genomic Surveillance of Respiratory Syncytial Virus: Insights From 25 Project Countries, 2019–2023
    Kenji O. Mfuh, Fernando Couto Motta, Thomas Williams, Nicole Wolter, Ian Barr, Clyde Dapat, Maria Cristina Fleischmann Alves Zambon, Lucy G. Mosscrop, Mei Shang, Sergejs Nikisins et al. · 2026 · Influenza and Other Respiratory Viruses
99. A Review of Respiratory Infection Caused by the Human Metapneumovirus: Occurrence, Epidemiology, Pathogenesis, Public Health Outcomes, and Intervention Strategies
    Sylvester Chibueze Izah, Matthew Chidozie Ogwu · 2026 · Health Science Reports
100. Structural Advances in Respiratory Syncytial Virus: Implications for Vaccine and Antiviral Development
     Xuanwei Huang, Caner Akıl, Peijun Zhang · 2026 · Microorganisms