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Cited by 588

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

Open access
Graham, Robert R, Cotsapas, Chris, Davies, Leela, Hackett, Rachel, Lessard, Christopher J, Leon, Joanlise M, Burtt, Noel P, Guiducci, Candace, Parkin, Melissa, Gates, Casey, Plenge, Robert M, Behrens, Timothy W, Wither, Joan E, Rioux, John D, Fortin, Paul R, Cunninghame Graham, Deborah, Wong, Andrew K, Vyse, Timothy J, Daly, Mark J, Altshuler, David, Moser, Kathy L, Gaffney, Patrick M·2008·Nature Genetics

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease influenced by genetic and environmental factors. We carried out a genome-wide association scan and replication study and found an association between SLE and a variant in TNFAIP3 (rs5029939, meta-analysis P = 2.89 × 10−12, OR = 2.29). We also found evidence of two independent signals near TNFAIP3 associated with SLE, including one previously associated with rheumatoid arthritis (RA). These results establish that variants near TNFAIP3 contribute to differential risk of SLE and RA.

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Metadata

Authors
Graham, R. R., Cotsapas, C., Davies, L., Hackett, R., Lessard, C. J., Leon, J. M., Burtt, N. P., Guiducci, C., Parkin, M., Gates, C., Plenge, R. M., Behrens, T. W., Wither, J. E., Rioux, J. D., Fortin, P. R., Cunninghame Graham, D., Wong, A. K., Vyse, T. J., Daly, M. J., Altshuler, D., Moser, K. L., & Gaffney, P. M.
Venue
Nature Genetics
Published
2008-08-01
Volume
40
Issue
9
Pages
1059-1061
ISSN
  • 1061-4036 (ISSN-L)
  • 1546-1718
OpenAlex
W2073167340
Cited by
588
References
1
FWCI
43.96
Type
journal article
Language
en
Open access
green

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