The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
Open accessAbstract
The TNFAIP3 (tumor necrosis factor alpha–induced protein 3) gene encodes a ubiquitin editing enzyme, A20, that restricts NF-κB–dependent signaling and prevents inflammation. We show that three independent SNPs in the TNFAIP3 region (rs13192841, rs2230926 and rs6922466) are associated with systemic lupus erythematosus (SLE) among individuals of European ancestry. These findings provide critical links between A20 and the etiology of SLE.
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Citations
Cites
Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice
Lee, E. G., Boone, D. L., Chai, S., Libby, S. L., Chien, M., Lodolce, J. P., & Ma, A. (2000) · Science · doi:10.1126/science.289.5488.2350 · Cited by 1,409
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Cited by
Jenks, S. A., Cashman, K. S., Zumaquero, E., Marigorta, U. M., Patel, A. V., Wang, X., Tomar, D., Woodruff, M. C., Simon, Z., Bugrovsky, R., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.08.015 · Cited by 1,078
Self-citationInternational MS Genetics Consortium, De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I. W., Ottoboni, L., Aggarwal, N. T., Piccio, L., Raychaudhuri, S., Tran, D., et al. (2009) · Nature Genetics · doi:10.1038/ng.401 · Cited by 800
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
Schuijs, M. J., Willart, M. A., Vergote, K., Gras, D., Deswarte, K., Ege, M. J., Madeira, F. B., Beyaert, R., van Loo, G., Bracher, F., et al. (2015) · Science · doi:10.1126/science.aac6623 · Cited by 576
A20: linking a complex regulator of ubiquitylation to immunity and human disease
Ma, A., & Malynn, B. A. (2012) · Nature Reviews Immunology · doi:10.1038/nri3313 · Cited by 548
Self-citationA20 in inflammation and autoimmunity
Catrysse, L., Vereecke, L., Beyaert, R., & van Loo, G. (2014) · Trends in Immunology · doi:10.1016/j.it.2013.10.005 · Cited by 493
Metadata
- Authors
- Musone, S. L., Taylor, K. E., Lu, T. T., Nititham, J., Ferreira, R. C., Ortmann, W., Shifrin, N., Petri, M. A., Ilyas Kamboh, M., Manzi, S., Seldin, M. F., Gregersen, P. K., Behrens, T. W., Ma, A., Kwok, P.-Y., & Criswell, L. A.
- Venue
- Nature Genetics
- Published
- 2008-08-01
- Volume
- 40
- Issue
- 9
- Pages
- 1062-1064
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W1963819091
- Cited by
- 470
- References
- 1
- FWCI
- 29.10
- Type
- journal article
- Language
- en
- Open access
- green
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- Musone, S. L., Taylor, K. E., Lu, T. T., Nititham, J., Ferreira, R. C., Ortmann, W., Shifrin, N., Petri, M. A., Ilyas Kamboh, M., Manzi, S., Seldin, M. F., Gregersen, P. K., Behrens, T. W., Ma, A., Kwok, P.-Y., & Criswell, L. A. (2008). Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nature Genetics. https://doi.org/10.1038/ng.202
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