The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations
Open accessAbstract
We conducted a joint (pooled) analysis of three genome-wide association studies (GWAS) of esophageal squamous cell carcinoma (ESCC) in individuals of Chinese ancestry (5,337 ESCC cases and 5,787 controls) with 9,654 ESCC cases and 10,058 controls for follow-up. In a logistic regression model adjusted for age, sex, study and two eigenvectors, two new loci achieved genome-wide significance, marked by rs7447927 at 5q31.2 (per-allele odds ratio (OR) = 0.85, 95% confidence interval (CI) = 0.82–0.88; P = 7.72 × 10−20) and rs1642764 at 17p13.1 (per-allele OR = 0.88, 95% CI = 0.85–0.91; P = 3.10 × 10−13). rs7447927 is a synonymous SNP in TMEM173, and rs1642764 is an intronic SNP in ATP1B2, near TP53. Furthermore, a locus in the HLA class II region at 6p21.32 (rs35597309) achieved genome-wide significance in the two populations at highest risk for ESSC (OR = 1.33, 95% CI = 1.22–1.46; P = 1.99 × 10−10). Our joint analysis identifies new ESCC susceptibility loci overall as well as a new locus unique to the population in the Taihang Mountain region at high risk of ESCC.
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
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Smyth, E. C., Lagergren, J., Fitzgerald, R. C., Lordick, F., Shah, M. A., Lagergren, P., & Cunningham, D. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.48 · Cited by 1,012
Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma
Ohashi, S., Miyamoto, S., Kikuchi, O., Goto, T., Amanuma, Y., & Muto, M. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.08.054 · Cited by 530
The impact of structural variation on human gene expression
GTEx Consortium, Chiang, C., Scott, A. J., Davis, J. R., Tsang, E. K., Li, X., Kim, Y., Hadzic, T., Damani, F. N., Ganel, L., et al. (2017) · Nature Genetics · doi:10.1038/ng.3834 · Cited by 495
Self-citationMagnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
Sivick, K. E., Desbien, A. L., Glickman, L. H., Reiner, G. L., Corrales, L., Surh, N. H., Hudson, T. E., Vu, U. T., Francica, B. J., Banda, T., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.047 · Cited by 451
Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China
He, L., He, L., Jin-Hu, F., You-Lin, Q., Jin-Hu, F., & You-Lin, Q. (2017) · Cancer Biology & Medicine · doi:10.20892/j.issn.2095-3941.2016.0093 · Cited by 359
Metadata
- Authors
- Wu, C., Wang, Z., Song, X., Feng, X.-S., Abnet, C. C., He, J., Hu, N., Zuo, X.-B., Tan, W., Zhan, Q., Hu, Z., He, Z., Jia, W., Zhou, Y., Yu, K., Shu, X.-O., Yuan, J.-M., Zheng, W., Zhao, X.-K., Gao, S.-G., Yuan, Z.-Q., Zhou, F.-Y., Fan, Z.-M., Cui, J.-L., Lin, H.-L., Han, X.-N., Li, B., Chen, X., Dawsey, S. M., Liao, L., Lee, M. P., Ding, T., Qiao, Y.-L., Liu, Z., Liu, Y., Yu, D., Chang, J., Wei, L., Gao, Y.-T., Koh, W.-P., Xiang, Y.-B., Tang, Z.-Z., Fan, J.-H., Han, J.-J., Zhou, S.-L., Zhang, P., Zhang, D.-Y., Yuan, Y., Huang, Y., Liu, C., Zhai, K., Qiao, Y., Jin, G., Guo, C., Fu, J., Miao, X., Lu, C., Yang, H., Wang, C., Wheeler, W. A., Gail, M., Yeager, M., Yuenger, J., Guo, E.-T., Li, A.-L., Zhang, W., Li, X.-M., Sun, L.-D., Ma, B.-G., Li, Y., Tang, S., Peng, X.-Q., Liu, J., Hutchinson, A., Jacobs, K., Giffen, C., Burdette, L., Fraumeni, J. F., Shen, H., Ke, Y., Zeng, Y., Wu, T., Kraft, P., Chung, C. C., Tucker, M. A., Hou, Z.-C., Liu, Y.-L., Hu, Y.-L., Liu, Y., Wang, L., Yuan, G., Chen, L.-S., Liu, X., Ma, T., Meng, H., Sun, L., Li, X.-M., Li, X.-M., Ku, J.-W., Zhou, Y.-F., Yang, L.-Q., Wang, Z., Li, Y., Qige, Q., Yang, W.-J., Lei, G.-Y., Chen, L.-Q., Li, E.-M., Yuan, L., Yue, W.-B., Wang, R., Wang, L.-W., Fan, X.-P., Zhu, F.-H., Zhao, W.-X., Mao, Y.-M., Zhang, M., Xing, G.-L., Li, J.-L., Han, M., Ren, J.-L., Liu, B., Ren, S.-W., Kong, Q.-P., Li, F., Sheyhidin, I., Wei, W., Zhang, Y.-R., Feng, C.-W., Wang, J., Yang, Y.-H., Hao, H.-Z., Bao, Q.-D., Liu, B.-C., Wu, A.-Q., Xie, D., Yang, W.-C., Wang, L., Zhao, X.-H., Chen, S.-Q., Hong, J.-Y., Zhang, X.-J., Freedman, N. D., Goldstein, A. M., Lin, D., Taylor, P. R., Wang, L.-D., & Chanock, S. J.
- Venue
- Nature Genetics
- Published
- 2014-09
- Volume
- 46
- Issue
- 9
- Pages
- 1001-1006
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2003751484
- Cited by
- 188
- References
- 3
- FWCI
- 16.13
- Type
- journal article
- Language
- en
- Open access
- green
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- Wu, C., Wang, Z., Song, X., Feng, X.-S., Abnet, C. C., He, J., Hu, N., Zuo, X.-B., Tan, W., Zhan, Q., Hu, Z., He, Z., Jia, W., Zhou, Y., Yu, K., Shu, X.-O., Yuan, J.-M., Zheng, W., Zhao, X.-K., . . . Chanock, S. J. (2014). Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. Nature Genetics. https://doi.org/10.1038/ng.3064
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