Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1

PLINK: a tool set for whole-genome association and population-based linkage analyses.

Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089

Haploview: analysis and visualization of LD and haplotype maps

Barrett, J. C., Fry, B., Maller, J., & Daly, M. J. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth457 · Cited by 14,551

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

Miki, Y., Swensen, J. J., Shattuck-Eidens, D. M., Futreal, P. A., Harshman, K., Tavtigian, S. V., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. (1994) · Science · doi:10.1126/science.7545954 · Cited by 6,069

The Structure of Haplotype Blocks in the Human Genome

Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863

Genome-wide association study identifies novel breast cancer susceptibility loci

Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., et al. (2007) · Nature · doi:10.1038/nature05887 · Cited by 2,319

Localization of a Breast Cancer Susceptibility Gene, BRCA2 , to Chromosome 13q12-13

Wooster, R., Neuhausen, S. L., Mangion, J., Quirk, Y., Ford, D., Collins, N., Nguyen, K. N., Seal, S., Tran, T. D., Averill, D., et al. (1994) · Science · doi:10.1126/science.8091231 · Cited by 1,918

Endogenous Sex Hormones and Breast Cancer in Postmenopausal Women: Reanalysis of Nine Prospective Studies

The Endogenous Hormones and Breast Cancer Collaborative Group (2002) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/94.8.606 · Cited by 1,799

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

Botstein, D., & Risch, N. (2003) · Nature Genetics · doi:10.1038/ng1090 · Cited by 1,503

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

Hunter, D. J., Kraft, P. L., Jacobs, K. B., Cox, D. G., Yeager, M., Hankinson, S. E., Wacholder, S., Wang, Z., Welch, R. A., Hutchinson, A. A., et al. (2007) · Nature Genetics · doi:10.1038/ng2075 · Cited by 1,487

Spectrum of Mutations in BRCA1, BRCA2, CHEK2, and TP53 in Families at High Risk of Breast Cancer

Walsh, T., Casadei, S., Coats, K. H., Swisher, E. M., Stray, S. M., Higgins, J., Roach, K. C., Mandell, J. B., Lee, M. K., Čierniková, S., et al. (2006) · JAMA · doi:10.1001/jama.295.12.1379 · Cited by 673

Finding the missing heritability of complex diseases

Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature · doi:10.1038/nature08494 · Cited by 8,336

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Michailidou, K., kConFab Investigators, Australian Ovarian Cancer Study Group, The GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network, Hall, P. N., González‐Neira, A., Ghoussaini, M., Dennis, J., Milne, R. L., Schmidt, M. K., et al. (2013) · Nature Genetics · doi:10.1038/ng.2563 · Cited by 1,080

Genome-wide association study identifies five new breast cancer susceptibility loci

The Breast Cancer Susceptibility Collaboration (UK), Turnbull, C., Ahmed, S., Morrison, J., Pernet, D., Renwick, A., Maranian, M., Seal, S., Ghoussaini, M., Hines, S., et al. (2010) · Nature Genetics · doi:10.1038/ng.586 · Cited by 687

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Study, A. O. C., Perry, J. R. B., The GENICA Network, kConFab, Study, T. L. C., The InterAct Consortium, Early Growth Genetics (EGG) Consortium, Day, F., Elks, C. E., Sulem, P., et al. (2014) · Nature · doi:10.1038/nature13545 · Cited by 604

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

BOCS, Michailidou, K., kConFab Investigators, AOCS Group, NBCS, GENICA Network, Beesley, J., Lindström, S., Canisius, S., Dennis, J., et al. (2015) · Nature Genetics · doi:10.1038/ng.3242 · Cited by 598

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

SEARCH, Ahmed, S., kConFab, Australian Ovarian Cancer Study Group, Thomas, G. D., Ghoussaini, M., Healey, C. S., Humphreys, M. K., Platte, R., Morrison, J., et al. (2009) · Nature Genetics · doi:10.1038/ng.354 · Cited by 470

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

ABCTB Investigators, Milne, R. L., EMBRACE, Collaborators, G. S., HEBON, kConFab/AOCS Investigators, Collaborators, N., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., et al. (2017) · Nature Genetics · doi:10.1038/ng.3785 · Cited by 415

Genetic susceptibility to breast cancer

Mavaddat, N., Antoniou, A. C., Easton, D. F., & García‐Closas, M. (2010) · Molecular Oncology · doi:10.1016/j.molonc.2010.04.011 · Cited by 407

Hereditary Breast Cancer: The Era of New Susceptibility Genes

Apostolou, P., & Fostira, F. (2013) · BioMed Research International · doi:10.1155/2013/747318 · Cited by 379

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., et al. (2017) · Nature Communications · doi:10.1038/ncomms15539 · Cited by 344

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

Peters, U., Jiao, S., Schumacher, F. R., Hutter, C. M., Aragaki, A. K., Baron, J. A., Berndt, S. I., Bezieau, S., Brenner, H., Butterbach, K., et al. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.12.020 · Cited by 324

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Jiang, D., Sun, J., Cao, G., Liu, Y., Lin, D., Gao, Y.-Z., Ren, W.-H., Long, X., Zhang, H., Ma, X.-P., et al. (2012) · Nature Genetics · doi:10.1038/ng.2483 · Cited by 308

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Ghoussaini, M., (FBCS), F. B. C. S., The Gene Environment Interaction of Breast Cancer in Germany (GENICA) Network, kConFab Investigators, Australian Ovarian Cancer Study Group, Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., et al. (2012) · Nature Genetics · doi:10.1038/ng.1049 · Cited by 285

Estrogen receptors and human disease: an update

Burns, K. A., & Korach, K. (2012) · Archives of Toxicology · doi:10.1007/s00204-012-0868-5 · Cited by 287

Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

Zhang, B., Beeghly-Fadiel, A. C., Long, J., & Zheng, W. (2011) · The Lancet Oncology · doi:10.1016/s1470-2045(11)70076-6 · Cited by 276

Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study

Fletcher, O., Johnson, N., Orr, N., Hosking, F. J., Gibson, L. J., Walker, K., Zélénika, D., Gut, I. G., Heath, S. C., Palles, C., et al. (2011) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djq563 · Cited by 237

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Zhang, B., Study, C. T. (., Colon Cancer Family Registry (CCFR), Jia, W.-H., Matsuda, K., Kweon, S., Matsuo, K., Xiang, Y.-B., Shin, A., Jee, S. H., et al. (2014) · Nature Genetics · doi:10.1038/ng.2985 · Cited by 229

Genetic Susceptibility to Triple-Negative Breast Cancer

Purrington, K. S., Vachon, C. M., & Couch, F. J. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-1699 · Cited by 229

Identification of New Genetic Risk Variants for Type 2 Diabetes

Shu, X. O., Long, J., Cai, Q., Qi, L., Xiang, Y., Cho, Y. S., Tai, E. S., Li, X., Xu, L., Chow, W., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001127 · Cited by 212

Familial Breast Cancer

Lalloo, F. I., & Evans, D. G. (2012) · Clinical Genetics · doi:10.1111/j.1399-0004.2012.01859.x · Cited by 220

The Contributions of Breast Density and Common Genetic Variation to Breast Cancer Risk

Vachon, C. M., Pankratz, V. S., Scott, C. G., Haeberle, L., Ziv, E., Jensen, M. R., Brandt, K. R., Whaley, D. H., Olson, J. E., Heusinger, K., et al. (2015) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju397 · Cited by 207

Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer

Jia, W., Colon Cancer Family Registry (CCFR), Zhang, B., Matsuo, K., Shin, A., Xiang, Y., Jee, S. H., Kim, D.-H., Ren, Z., Cai, Q., et al. (2012) · Nature Genetics · doi:10.1038/ng.2505 · Cited by 186

Genome-Wide Association Studies of Cancer

Stadler, Z. K., Thom, P., Robson, M. E., Weitzel, J. N., Kauff, N. D., Hurley, K. E., Devlin, V., Gold, B., Klein, R. J., & Offit, K. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.25.7816 · Cited by 188

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

Xu, J., Mo, Z., Ye, D., Wang, M., Liu, F., Jin, G., Xu, C., Wang, X., Shao, Q., Chen, Z., et al. (2012) · Nature Genetics · doi:10.1038/ng.2424 · Cited by 182

The pursuit of genome-wide association studies: where are we now?

Ku, C., Loy, E. Y., Yudi Pawitan, Y., & Chia, K. S. (2010) · Journal of Human Genetics · doi:10.1038/jhg.2010.19 · Cited by 184

Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

Antoniou, A. C., Beesley, J., McGuffog, L., Sinilnikova, O. M., Healey, S. C., Neuhausen, S. L., Ding, Y. C., Rebbeck, T. R., Weitzel, J. N., Lynch, H. T., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-1907 · Cited by 182

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Siddiq, A., Couch, F. J., Chen, G. K., Lindström, S., Eccles, D., Millikan, R. C., Michailidou, K., Stram, D. O., Beckmann, L., Rhie, S. K., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds381 · Cited by 173

Genome measures used for quality control are dependent on gene function and ancestry

Wang, J., Raskin, L., Samuels, D. C., Shyr, Y., & Guo, Y. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btu668 · Cited by 173

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Broeks, A., Schmidt, M. K., Sherman, M. E., Couch, F. J., Hopper, J. L., Dite, G. S., Apicella, C., Smith, L. D., Hammet, F., Southey, M. C., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr228 · Cited by 168

Current status of genome-wide association studies in cancer

Chung, C. C., & Chanock, S. J. (2011) · Human Genetics · doi:10.1007/s00439-011-1030-9 · Cited by 166

Personalized Medicine: Marking a New Epoch in Cancer Patient Management

Diamandis, M., White, N. M. A., & Yousef, G. M. (2010) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-10-0264 · Cited by 170

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

EMBRACE, Dunning, A. M., Collaborators, G. S., HEBON, kConFab Investigators, Michailidou, K., Kuchenbaecker, K. B., Thompson, D., French, J. D., Beesley, J., et al. (2016) · Nature Genetics · doi:10.1038/ng.3521 · Cited by 161

Polygenic susceptibility to prostate and breast cancer: implications for personalised screening

Pashayan, N., Duffy, S. W., Chowdhury, S., Dent, T., Burton, H., Neal, D. E., Easton, D. F., Eeles, R. A., & Pharoah, P. D. P. (2011) · British Journal of Cancer · doi:10.1038/bjc.2011.118 · Cited by 160

Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium

Campa, D., Kaaks, R., Marchand, L. L., Haiman, C. A., Travis, R. C., Berg, C. D., Buring, J. E., Chanock, S. J., Diver, W. R., Dostal, L., et al. (2011) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djr265 · Cited by 157

Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer

Galvan, A., Ioannidis, J. P. A., & Dragani, T. A. (2010) · Trends in Genetics · doi:10.1016/j.tig.2009.12.008 · Cited by 156

Genomic actions of estrogen receptor α: what are the targets and how are they regulated?

Welboren, W.-J., Sweep, F. C. G. J., Span, P. N., & Stunnenberg, H. G. (2009) · Endocrine Related Cancer · doi:10.1677/erc-09-0086 · Cited by 161

Common Genetic Variation and Breast Cancer Risk—Past, Present, and Future

Lilyquist, J., Ruddy, K. J., Vachon, C. M., & Couch, F. J. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-17-1144 · Cited by 158

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

Cai, Q., Zhang, B., Sung, H., Low, S., Kweon, S., Lü, W., Shi, J., Long, J., Wen, W., Choi, J., et al. (2014) · Nature Genetics · doi:10.1038/ng.3041 · Cited by 152

Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

Long, J., Cai, Q., Sung, H., Shi, J., Zhang, B., Choi, J., Wen, W., Delahanty, R., Lu, W., Gao, Y.-T., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002532 · Cited by 150

Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study

Evans, D. G., Astley, S., Stavrinos, P., Harkness, E. F., Donnelly, L. S., Dawe, S., Jacob, I., Harvie, M., Cuzick, J. M., Brentnall, A. R., et al. (2016) · Programme Grants for Applied Research · doi:10.3310/pgfar04110 · Cited by 153

Leveraging Genetic Variability across Populations for the Identification of Causal Variants

Zaitlen, N., Paşaniuc, B., Gur, T., Ziv, E., & Halperin, E. (2010) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.11.016 · Cited by 142

Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25

Fejerman, L., Ahmadiyeh, N., Hu, D., Huntsman, S., Beckman, K. B., Caswell-Jin, J. L., Tsung, K., John, E. M., Torres-Mejı́a, G., Carvajal‐Carmona, L. G., et al. (2014) · Nature Communications · doi:10.1038/ncomms6260 · Cited by 147

Integrated Analysis of Gene Expression, CpG Island Methylation, and Gene Copy Number in Breast Cancer Cells by Deep Sequencing

Sun, Z., Asmann, Y. W., Kalari, K. R., Bot, B. M., Eckel‐Passow, J. E., Baker, T. R., Carr, J. M., Khrebtukova, I., Luo, S. J., Zhang, L., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017490 · Cited by 148

Exome sequencing generates high quality data in non-target regions

Guo, Y. P., Long, J., He, J., Li, C.-I., Cai, Q., Shu, X., Zheng, W., & Li, C. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-194 · Cited by 143

The effect of strand bias in Illumina short-read sequencing data

Guo, Y. P., Li, J., Li, C.-I., Long, J., Samuels, D. C., & Shyr, Y. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-666 · Cited by 140

A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

Long, J., Delahanty, R., Li, G., Gao, Y., Lu, W., Cai, Q., Xiang, Y., Li, C., Ji, B., Zheng, Y., et al. (2013) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djt018 · Cited by 144

A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study

Kim, H.-C., Lee, J., Sung, H., Choi, J., Park, S. K., Lee, K.-M., Kim, Y. J., Go, M. J., Li, L., Cho, Y. S., et al. (2012) · Breast Cancer Research · doi:10.1186/bcr3158 · Cited by 138

RAD51C is a susceptibility gene for ovarian cancer

Pelttari, L. M., Heikkinen, T., Thompson, D. J., Kallioniemi, A. H., Schleutker, J., Holli, K., BLOMQVIST, C. P., Aittomäki, K., Bützow, R. C., & Nevanlinna, H. A. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr229 · Cited by 141

Identifying breast cancer susceptibility genes – a review of the genetic background in familial breast cancer

Wendt, C., & Margolin, S. (2019) · Acta Oncologica · doi:10.1080/0284186x.2018.1529428 · Cited by 144

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

Lindström, S., Thompson, D. J., Paterson, A. D., Li, J., Gierach, G. L., Scott, C. G., Stone, J., Douglas, J. A., dos‐Santos‐Silva, I., Fernández‐Navarro, P., et al. (2014) · Nature Communications · doi:10.1038/ncomms6303 · Cited by 133

Identification of a Functional Genetic Variant at 16q12.1 for Breast Cancer Risk: Results from the Asia Breast Cancer Consortium

Long, J., Cai, Q., Shu, X., Qu, S., Li, C., Zheng, Y., Gu, K., Wang, W., Xiang, Y.-B., Cheng, J., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001002 · Cited by 129

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci

Baxter, J. S., Leavy, O. C., Dryden, N. H., Maguire, S. L., Johnson, N., Fedele, V., Simigdala, N., Martin, L., Andrews, S., Wingett, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03411-9 · Cited by 123

Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

Ma, X., Zhang, B., & Zheng, W. (2013) · Gut · doi:10.1136/gutjnl-2012-304121 · Cited by 125

Pathway Analysis of Breast Cancer Genome-Wide Association Study Highlights Three Pathways and One Canonical Signaling Cascade

Menashe, I., Maeder, D. L., García‐Closas, M., Figueroa, J. D., Bhattacharjee, S., Rotunno, M., Kraft, P. L., Hunter, D. J., Chanock, S. J., Rosenberg, P. S., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4502 · Cited by 127

FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women

Barnholtz‐Sloan, J. S., Shetty, P. B., Guan, X., Nyante, S. J., Luo, J., Brennan, D. J., & Millikan, R. C. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq128 · Cited by 124

Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement

Darabi, H., Czene, K., Zhao, W., Liu, J., Hall, P. N., & Humphreys, K. (2012) · Breast Cancer Research · doi:10.1186/bcr3110 · Cited by 123

Gene–environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study

Travis, R. C., REEVES, G. K., Green, J., Bull, D., Tipper, S. J., Baker, K., Beral, V., Peto, R., Bell, J. I., Zélénika, D., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60636-8 · Cited by 127

Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data

Liu, Q., Guo, Y. P., Li, J., Long, J., Zhang, B., & Shyr, Y. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-s8-s8 · Cited by 126

Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer

Purrington, K. S., Vachon, C. M., Lee, A. M., Slager, S., Lesnick, T. G., Olswold, C., Fasching, P. A., Miron, P. L., Eccles, D., Carpenter, J., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1266 · Cited by 119

Assessing Individual Breast Cancer Risk within the U.K. National Health Service Breast Screening Program: A New Paradigm for Cancer Prevention

Evans, D. G., Warwick, J., Astley, S., Stavrinos, P., Sahin, S., Ingham, S. L., McBurney, H., Eckersley, B., Harvie, M., Wilson, M., et al. (2012) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-11-0458 · Cited by 123

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Mulligan, A. M., Couch, F. J., Barrowdale, D., Domchek, S. M., Eccles, D., Nevanlinna, H. A., Ramus, S. J., Robson, M. E., Sherman, M. E., Spurdle, A. B., et al. (2011) · Breast Cancer Research · doi:10.1186/bcr3052 · Cited by 113

Genetic and Clinical Predictors for Breast Cancer Risk Assessment and Stratification Among Chinese Women

Zheng, W., Wen, W., Gao, Y.-T., Shyr, Y., Zheng, Y., Long, J., Li, G., Li, C., Gu, K., Cai, Q., et al. (2010) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djq170 · Cited by 110

Genome-wide association studies in cancer--current and future directions

Chung, C. C., Magalhães, W. C. S., Bosquet, J. G., & Chanock, S. J. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp273 · Cited by 110

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandiño, G., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms11375 · Cited by 110

Incidence of Breast Cancer and Its Subtypes in Relation to Individual and Multiple Low-Penetrance Genetic Susceptibility Loci

REEVES, G. K., Travis, R. C., Green, J., Bull, D., Tipper, S. J., Baker, K., Beral, V., Peto, R., Bell, J. I., Zélénika, D., et al. (2010) · JAMA · doi:10.1001/jama.2010.1042 · Cited by 109

Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk

Vachon, C. M., Scott, C. G., Fasching, P. A., Hall, P. N., Tamimi, R. M., Li, J., Stone, J., Apicella, C., Odefrey, F., Gierach, G. L., et al. (2012) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-12-0066 · Cited by 108

Ancestry-Shift Refinement Mapping of the C6orf97-ESR1 Breast Cancer Susceptibility Locus

Stacey, S., Sulem, P., Zanon, C., Gudjonsson, S. A., Þorleifsson, G., Helgason, A., Jónasdóttir, Á., Besenbacher, S., Kostic, J. P., Fackenthal, J. D., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001029 · Cited by 104

ESR1/SYNE1 Polymorphism and Invasive Epithelial Ovarian Cancer Risk: An Ovarian Cancer Association Consortium Study

Doherty, J. A., Rossing, M. A., Cushing‐Haugen, K. L., Chen, C., Berg, D. J. V. D., Wu, A. H., Pike, M. C., Ness, R. B., Moysich, K. B., Chenevix‐Trench, G., et al. (2010) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-09-0729 · Cited by 106

Evaluation of Breast Cancer Susceptibility Loci in Chinese Women

Long, J., Shu, X., Cai, Q., Gao, Y., Zheng, Y., Li, G., Li, C., Gu, K., Wen, W., Xiang, Y., et al. (2010) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-10-0054 · Cited by 103

Genome-Wide Association Studies of Skeletal Phenotypes: What We Have Learned and Where We Are Headed

Hsu, Y., & Kiel, D. P. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1890 · Cited by 109

Genome-wide association studies in common cancers—what have we learnt?

Varghese, J. S., & Easton, D. F. (2010) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2010.03.012 · Cited by 105

Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer

Bailey, S. D., Desai, K., Kron, K. J., Mazrooei, P., Sinnott-Armstrong, N., Treloar, A. E., Dowar, M., Thu, K. L., Cescon, D. W., Silvester, J., et al. (2016) · Nature Genetics · doi:10.1038/ng.3650 · Cited by 101

Inherited Genetic Susceptibility to Breast Cancer

Ghoussaini, M., Pharoah, P. D. P., & Easton, D. F. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.07.003 · Cited by 102

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

Mokrý, M., Feitsma, H., Nijman, I. J., de Bruijn, E., van der Zaag, P. J., Guryev, V., & Cuppen, E. P. J. G. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq072 · Cited by 101

Differences in Incidence, Mortality and Survival of Breast Cancer by Regions and Countries in Asia and Contributing Factors

Kim, Y.-J., Yoo, K., & Goodman, M. T. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2015.16.7.2857 · Cited by 100

Identification of non-coding silencer elements and their regulation of gene expression

Pang, B., van Weerd, J. H., Hamoen, F. L., & Snyder, M. P. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00549-9 · Cited by 101

Male breast cancer: genetics, epigenetics, and ethical aspects

Rizzolo, P., Silvestri, V., Tommasi, S., Pinto, R., Danza, K., Falchetti, M., Gulino, M., Frati, P., & Ottini, L. (2013) · Annals of Oncology · doi:10.1093/annonc/mdt316 · Cited by 102

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Fachal, L., & Dunning, A. M. (2015) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2015.01.004 · Cited by 103

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Cai, Q., Long, J., Lu, W., Qu, S., Wen, W., Kang, D., Lee, J., Chen, K., Shen, H., Shen, C., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr405 · Cited by 96

A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population

Sueta, A., Ito, H. M., Kawase, T., Hirose, K., Hosono, S., Yatabe, Y., Tajima, K., Tanaka, H., Iwata, H., Iwase, H., et al. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1904-5 · Cited by 94

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Milne, R. L., & Antoniou, A. C. (2011) · Annals of Oncology · doi:10.1093/annonc/mdq660 · Cited by 100

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Li, J., Humphreys, K., Heikkinen, T., Aittomäki, K., BLOMQVIST, C. P., Pharoah, P. D. P., Dunning, A. M., Ahmed, S., Hooning, M. J., Martens, J. W. M., et al. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-1172-9 · Cited by 94

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Shan, J., Mahfoudh, W., DSouza, S. P., Hassen, E., Bouaouina, N., Abdelhak, S., Benhadjayed, A., Memmi, H., Mathew, R., Aigha, I. I., et al. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2202-6 · Cited by 93

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

Zheng, W., Zhang, B., Cai, Q., Sung, H., Michailidou, K., Shi, J., Choi, J., Long, J., Dennis, J., Humphreys, M. K., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt089 · Cited by 94

Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies

Peng, S., Lü, B., Ruan, W., Zhu, Y., Sheng, H., & Lai, M. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1459-5 · Cited by 94

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Palmer, J. R., Ruiz-Narváez, E., Rotimi, C. N., Cupples, L. A., Cozier, Y. C., Adams-Campbell, L. L., & Rosenberg, L. A. (2012) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-12-0769 · Cited by 89

Genomic Analyses of Hormone Signaling and Gene Regulation

Cheung, E. C. W., & Kraus, W. L. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135840 · Cited by 86

Evaluation of 11 Breast Cancer Susceptibility Loci in African-American Women

Zheng, W., Cai, Q., Signorello, L. B., Long, J., Hargreaves, M. K., Deming, S. L., Li, G., Li, C., Cui, Y., & Blot, W. J. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-09-0624 · Cited by 83

Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women

Long, J., Zhang, B., Signorello, L. B., Cai, Q., Deming-Halverson, S. L., Shrubsole, M. J., Sanderson, M., Dennis, J., Michailidou, K., Easton, D. F., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058350 · Cited by 85

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

Ahsan, H., Halpern, J., Kibriya, M. G., Pierce, B. L., Lin, T., Gamazon, E. R., McGuire, V. M., Felberg, A., Shi, J., Jasmine, F., et al. (2014) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-13-0340 · Cited by 85

Genome-wide mechanisms of nuclear receptor action

Biddie, S. C., John, S., & Hager, G. L. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.08.006 · Cited by 83

Nesprins in health and disease

Cartwright, S., & Karakesisoglou, I. (2013) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2013.12.010 · Cited by 79

Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Dixit, A., Yi, L., Gowthaman, R., Torkamani, A., Schork, N. J., & Verkhivker, G. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007485 · Cited by 83

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium†

Figueroa, J. D., García‐Closas, M., Humphreys, M. K., Platte, R., Hopper, J. L., Southey, M. C., Apicella, C., Hammet, F., Schmidt, M. K., Broeks, A., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr368 · Cited by 80

Evaluation of polygenic risk scores for predicting breast and prostate cancer risk

Machiela, M. J., Chen, C., Chen, C., Chanock, S. J., Hunter, D. J., & Kraft, P. L. (2011) · Genetic Epidemiology · doi:10.1002/gepi.20600 · Cited by 78

A genome-wide association study of breast cancer in women of African ancestry

Chen, F., Chen, G. K., Stram, D. O., Millikan, R. C., Ambrosone, C. B., John, E. M., Bernstein, L., Zheng, W., Palmer, J. R., Hu, J. J., et al. (2012) · Human Genetics · doi:10.1007/s00439-012-1214-y · Cited by 80

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

Wang, X., Pankratz, V. S., Fredericksen, Z., Tarrell, R. F., Karaus, M., McGuffog, L., Pharaoh, P. D. P., Ponder, B. A. J., Dunning, A. M., Peock, S., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq174 · Cited by 77

Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers

Milne, R. L., & Antoniou, A. C. (2016) · Endocrine Related Cancer · doi:10.1530/erc-16-0277 · Cited by 84

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

Antoniou, A. C., Kartsonaki, C., Sinilnikova, O. M., Soucy, P., McGuffog, L., Healey, S. C., Lee, A., Peterlongo, P., Manoukian, S., Peissel, B., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr226 · Cited by 74

Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants

Shu, X., Long, J., Cai, Q., Kweon, S., Choi, J., Kubo, M., Park, S. K., Bolla, M. K., Dennis, J., Wang, Q., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15046-w · Cited by 78

Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Hein, R., Maranian, M. J., Hopper, J. L., Kapuscinski, M. K., Southey, M. C., Park, D. J., Schmidt, M. K., Broeks, A., Hogervorst, F. B. L., Bueno-de-Mesquita, H. B., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042380 · Cited by 54

Genetic variants of 6q25 and breast cancer susceptibility: a two-stage fine mapping study in a Chinese population

Han, J., Jiang, T., Bai, H., Gu, H., Dong, J., Ma, H., Hu, Z., & Shen, H. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1527-x · Cited by 21

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Cai, Q., Wen, W., Qu, S., Li, G., Egan, K. M., Chen, K., Deming, S. L., Shen, H., Shen, C.-Y., Gammon, M. D., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-2733 · Cited by 85

Association between a novel polymorphism (rs2046210) of the 6q25.1 locus and breast cancer risk

Yang, Z., Shen, J., Cao, Z., & Wang, B. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-013-2494-1 · Cited by 18

Sequencing of Chromosomal Locus 6q25.1 Revealed Two Significant SNPs rs2046210 and rs2046211 Associated with Breast Cancer: A Case-Control Study in Egyptian Women

Saied, M. H., Rizk, M. M., Sayed, N. E., Mostafa, S., Marzouk, S., & Fayed, H. M. A. (2022) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2022.23.4.1359