Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4

NISC Comparative Sequencing Program, Prickett, Todd D, Agrawal, Neena S, Wei, Xiaomu, Yates, Kristin E, Lin, Jimmy C, Wunderlich, John R, Cronin, Julia C +3 more·2009·Nature Genetics

DOI 10.1038/ng.438

Cited by (352)

Items 101–200 of 352

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Yong Qing Lin, Zhixiong Wu, Weijian Guo, J Li · 2015 · Tumor Biology
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Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
Yosef Yarden, Deric L. Wheeler · 2014 · Springer eBooks
Her4 promotes cancer metabolic reprogramming via the c-Myc-dependent signaling axis
Jing Han, Yangfeng Zhang, Jing Xu, Tao Zhang, Hongsheng Wang, Zhuoying Wang, Yafei Jiang, Lei Zhou, Mengkai Yang, Yingqi Hua et al. · 2020 · Cancer Letters
Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner
Femina Rauf, Fernanda Festa, Jin G. Park, Mitchell Magee, Seron Eaton, Capria Rinaldi, Carlos Morales Betanzos, Laura G. Gonzalez-Malerva, Joshua LaBaer · 2018 · Oncogene
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Youqun Tang, Yanming Cao · 2022 · Disease Markers
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Xiaomu Wei, Ángela Moncada-Pazos, Santiago Cal, Clara Soria‐Valles, Jared J. Gartner, Udo Rudloff, Jimmy Lin, NISC Comparative Sequencing Program, Steven A. Rosenberg, Carlos López-Otı́n et al. · 2011 · Human Mutation
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Massimiliano Tognolini, Matteo Incerti, Iftiin Hassan‐Mohamed, Carmine Giorgio, Simonetta Russo, Renato Bruni, Barbara Lelli, Luisa Bracci, Roberta Noberini, Elena Bianca Pasquale et al. · 2012 · ChemMedChem
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Maria Domenica Castellone, Antonella Verrienti, Deva Magendhra Rao, Marialuisa Sponziello, Dora Fabbro, Magesh Muthu, Cosimo Durante, Marianna Maranghi, Giuseppe Damante, Stefano Pizzolitto et al. · 2009 · Clinical Endocrinology
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Rosalin Mishra, Samar Alanazi, Long Yuan, Thomas Solomon, Tarjani M. Thaker, Natalia Jura, Joan T. Garrett · 2018 · Oncotarget
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Soo Young Cho, Minhye Choi, Hyo-Jeong Ban, Chang Hyeon Lee, Soojun Park, Han Kyeom Kim, Young‐Sik Kim, Young Seek Lee, Ji-Yun Lee · 2016 · Oncotarget
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Andrew Shih, Shannon Telesco, Sung-Hee Choi, Mark A. Lemmon, Ravi Radhakrishnan · 2011 · Biochemical Journal
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Valda C. Hilliard, Mark R. Frey, Peter J. Dempsey, Richard M. Peek, D. Brent Polk · 2011 · American Journal of Physiology-Gastrointestinal and Liver Physiology
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Daniel S. Peeper · 2011 · Pigment Cell & Melanoma Research
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A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial
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Targeting Receptor Tyrosine Kinases in Cancer
Wolfgang J. Köstler, Christoph Carl Zielinski · 2014 · Springer eBooks
Integrating proteomics into precision oncology
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Raphael Trenker, Devan C. Diwanji, Tanner Bingham, Kliment A. Verba, Natalia Jura · 2023 · eLife
Afatinib in the treatment of head and neck squamous cell carcinoma
Renata Ferrarotto, Kathryn Ann Gold · 2013 · Expert Opinion on Investigational Drugs
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Jacqueline F. Donoghue, Lauren Kerr, Naomi Alexander, Sameer A. Greenall, Anthony Longano, Nicholas G. Gottardo, Rong Wang, Viviane S. Tabar, Timothy E. Adams, Paul S. Mischel et al. · 2018 · Cancers
Macroenvironment-gene-microenvironment interactions in ultraviolet radiation-induced melanomagenesis
Xuan Mo, Sarah Preston, M. Raza Zaidi · 2019 · Advances in cancer research
ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment
Christopher C. Lau, Keith J. Killian, Yardena Samuels, Udo Rudloff · 2013 · Methods in molecular biology
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Djerf Severinsson, Emelie A., Trinks, Cecilia, Gréen, Henrik, Abdiu, Avni, Hallbeck, Anna-Lotta, Stål, Olle, Walz, Thomas M. · 2011 · Biochemical and Biophysical Research Communications
Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines
Ewelina Dratkiewicz, Katarzyna Pietraszek‐Gremplewicz, Aleksandra Simiczyjew, Antonina Joanna Mazur, Dorota Nowak · 2018 · Oncotarget
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Claudia Capparelli, Sheera R. Rosenbaum, Lisa D. Berman-Booty, Amel Salhi, Nadège Gaborit, Tingting Zhan, Inna Chervoneva, Jason Roszik, Scott Eric Woodman, Michael A. Davies et al. · 2015 · Cancer Research
Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families
Tai Wai Wong, Francis Y. Lee, Stuart L. Emanuel, Craig R. Fairchild, Joseph Fargnoli, Brian E. Fink, Ashvinikumar V. Gavai, Amy Hammell, Benjamin Henley, Christine Hilt et al. · 2011 · Clinical Cancer Research
A polymorphism withinErbB4is associated with risk for hepatocellular carcinoma in Chinese population
Qiang Yu · 2012 · World Journal of Gastroenterology
Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases
Andrew Shih, Shannon Telesco, Ravi Radhakrishnan · 2011 · Cancers
Functional interplay between secreted ligands and receptors in melanoma
Cecilia Herráiz, Celia Jiménez‐Cervantes, Berta L. Sánchez‐Laorden, José Carlos García-Borrón · 2017 · Seminars in Cell and Developmental Biology
Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma
Tingting Chen, Lan Zhou, Hua Li, Tian Yuan, Junqin Li, Lihua Dong, Yuhua Zhao, Dapeng Wei · 2017 · Oncology Letters
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Tanase Timis, Jón Þór Bergþorsson, Victor Greiff, Mihai Cenariu, Diana Cenariu · 2023 · Current Issues in Molecular Biology
Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening
Assunta Giordano, Giovanni Forte, Luigia Massimo, Raffaele Riccio, Giuseppe Bifulco, Simone Di Micco · 2018 · European Journal of Medicinal Chemistry
Modelling of Protein Kinase Signaling Pathways in Melanoma and Other Cancers
Manfred Kunz, Julio Vera · 2019 · Cancers
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Corey Rogers, Jennifer J. D. Morrissette, Robyn T. Sussman · 2021 · Cancer Genetics
Obesity and melanoma: Exploring molecular links
Jiezhong Chen, Mengna Chi, Chen Chen, Xu Dong Zhang · 2013 · Journal of Cellular Biochemistry
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