Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4

NISC Comparative Sequencing Program, Prickett, Todd D, Agrawal, Neena S, Wei, Xiaomu, Yates, Kristin E, Lin, Jimmy C, Wunderlich, John R, Cronin, Julia C +3 more·2009·Nature Genetics
DOI 10.1038/ng.438

Cited by (352)

Items 301–352 of 352

  1. Melanoma researchers have a reason to GRIN: melanoma yields more of its secrets to exome sequencing
    Paul S. Meltzer · 2011 · Pigment Cell & Melanoma Research
  2. Unveiling the Molecular Mechanisms Regulating the Activation of the ErbB Family Receptors at Atomic Resolution through Molecular Modeling and Simulations
    Andrew Shih · 2011 · ScholarlyCommons (University of Pennsylvania)
  3. Roles of EEF1A2 & PTK6 in breast cancer
    Mariam Fida · 2011 · ERA
  4. ERBB4 mutations in cancer and amyotrophic lateral sclerosis
    Kari J. Kurppa · 2014 · UTUPub (University of Turku)
  5. Cancer Genome Sequencing
    Chee‐Seng Ku, Nasheen Naidoo, Mikael Hartman, Yudi Pawitan Y · 2010 · Encyclopedia of Life Sciences
  6. Molecular Pathology of Cutaneous Melanoma and Nonmelanoma Skin Cancer
    Andrea Saggini, Boris C. Bastian · 2012 · Springer eBooks
  7. CHARACTERIZATION OF ERBB4 EXPRESSION IN OSTEOSARCOMA
    Nupur Lala · 2015 · Digital Commons-TMC (Texas Medical Center)
  8. Novel Players in the Integrin Signaling Orchestra: TCPTP and MDGI
    Jonna Nevo · 2011 · UTUPub (University of Turku)
  9. Role of ErbB2 and ErbB4 in Cancer Growth, Prognosis and as Targets for Immunotherapy
    Maija Hollmén · 2010 · UTUPub (University of Turku)
  10. Novel Functions of ErbB4 and NRG-1 in Development and Cancer
    Ilkka Paatero · 2013 · UTUPub (University of Turku)
  11. Mutational analysis of the extracellular domain of ERBB4 gene in common carcinomas
    Min Sung Kim, Nam Jin Yoo, Sug Hyung Lee · 2011 · Pathology
  12. Expressão da dermicidina e correlações clínico-patológicas em melanomas malignos
    Beatriz A. Sangiuliano · 2016
  13. Genetics of Diabetic Micro- and Macrovascular Complications
    Niina Sandholm, Per‐Henrik Groop, Alessandro Doria · 2016 · Springer eBooks
  14. Human Epidermal Growth Factor Receptor (HER) Family Molecular Structure
    Mark Daniel Pegram, Ralf Landgraf · 2016 · Springer eBooks
  15. Einfluss von Risikofaktoren, Umständen der Diagnosestellung und Früherkennungsmaßnahmen auf die Tumordicke nach Breslow bei Patienten mit malignem Melanom
    Hoffmann, Saskia Luise · 2016
  16. Aktuelle molekulare Diagnostik beim malignen Melanom
    Manfred Kunz · 2017 · Aktuelle Dermatologie
  17. Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma
    Michael A. Davies · 2014 · Cancer drug discovery and develogment/Cancer drug discovery and development
  18. Anticuerpos conjugados a fármacos frente a receptores ERBB: nuevas indicaciones y mecanismos de resistencia
    Sara García Alonso · 2018
  19. Identification of a genetic contribution to Meniere's disease
    Colleen A. Campbell · 2010
  20. An investigation of imaging approaches for the study of erbb2 distribution and dynamics in the plasma membrane with respect to the distribution of the tetraspanin cd82
    Emma Lonnen · 2018 · University of Birmingham Institutional Research Archive (University of Birmingham)
  21. Exploring molecular patterns and determinants of melanoma cell susceptibility to natural killer cell cytotoxicity
    Sabrina Cappello · 2020
  22. Identification of Novel Targets for Therapy in Solid Tumors
    Katherine E. Hutchinson · 2015
  23. Targeting the EPHA2 receptor tyrosine kinase in KRAS and EGFR mutant lung cancer
    Katherine R. Amato · 2015
  24. THE EPHA2/EPHRIN-A1 AXIS REGULATES HOST-TUMOR INTERACTIONS
    Eileen F. Shiuan · 2020
  25. Faculty Opinions recommendation of New susceptibility loci associated with kidney disease in type 1 diabetes.
    Vladimir N. Marshansky · 2012 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  26. Melanoma Genetics and Genomics
    Goran B Jönsson, Hensin Tsao · 2011 · Springer eBooks
  27. Metastatic melanoma
    Rafael Rosell · 2012
  28. Tumours of the skin
    Edel A. O’Toole · 2020
  29. ERBB4 Mutant Alleles Found in BRAF WT Melanomas That Drive the Proliferation of a BRAF WT Melanoma Cell Line
    Lauren M. Lucas, Richard Lee Cullum, Joelle N. Woggerman, Vipasha Dwivedi, Jessica A. Markham, Connor M. Kelley, Elizabeth L. Knerr, Laura J. Cook, Megan A. Jacobi, Darby C. Taylor et al. · 2022 · medRxiv
  30. Targeted Molecular Therapy for Ovarian Cancer Patients
    Samir A. Farghaly · 2022 · Springer eBooks
  31. Supplementary Table 2 from A High-Throughput Panel for Identifying Clinically Relevant Mutation Profiles in Melanoma
    Ken Dutton‐Regester, Darryl Luke Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda J. O'Connor, Michael F. O’Rourke et al. · 2023
  32. Data from Mutational and Functional Analysis Reveals ADAMTS18 Metalloproteinase as a Novel Driver in Melanoma
    Xiaomu Wei, Todd D. Prickett, Cristina G. Viloria, Alfredo Molinolo, Jimmy Lin, Isabel Cárdenas-Navia, Pedro E. Cruz, Steven A. Rosenberg, Michael A. Davies, Jeffrey E. Gershenwald et al. · 2023
  33. Data from Meta-Analysis and Systematic Review of the Genomics of Mucosal Melanoma
    Natasa Broit, Peter A. Johansson, Chloe B. Rodgers, Sebastian Walpole, Felicity Newell, Nicholas K. Hayward, Antonia L. Pritchard · 2023
  34. Identification of modifier genes/networks of lysosomal biology
    Ányelo Alberto Duran Mojica · 2023
  35. Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
    Raphael Trenker, Devan C. Diwanji, Tanner Bingham, Kliment A. Verba, Natalia Jura · 2024 · eLife
  36. Reviewer #2 (Public Review): Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
    2024 · eLife
  37. Author Response: Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
    Raphael Trenker, Devan C. Diwanji, Tanner Bingham, Kliment A. Verba, Natalia Jura · 2024 · eLife
  38. Molecular Characterization of Vascular Transformation of Lymph Node Sinuses via Oncomine Comprehensive Assay
    Shaymaa E. Hegazy, Rana Naous · 2025 · International Journal of Surgical Pathology
  39. Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
    Marium Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen Keon Ciombor, Mary Kay Washington, Kamran Idrees · 2025 · Molecular Oncology
  40. Experimental studies on ErbB targeted therapy in malignant melanoma
    Emelie Severinsson · 2012 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  41. Expression and Mutation Analyses of Candidate Cancer Genes In Situ
    Sara Kiflemariam · 2012 · Uppsala University Publications (Uppsala University)
  42. Evaluation of clonality in lentigo maligna
    Sophie Soyeon Lim, Peinan Zhao, Nicholas C. Wong, Pacman Szeto, Trevor Wilson, Helen Mitchell, Ismael A. Vergara, Francesco‐Raffaele Bruscino‐Raiola, Christopher F. McCormack, Angela Webb et al. · 2025 · Journal of Investigative Dermatology
  43. The CHD4 NuRD complex links epigenetics to glycolytic flux and proliferation of melanoma and a variety of cancer cells
    Sébastien Coassolo · 2019 · theses.fr (ABES)
  44. Plant virus-derived nanoparticles for the imaging and treatment of cancer
    Coralie Gamper · 2019 · theses.fr (ABES)
  45. A comprehensive single cell atlas of healthy ocular tissue and uveal melanoma reveals mutation- and uveal tract-associated cell states
    Mitchell Paul Levesque, Victoria Hermes, Mauro Esposito, Kelly M. Brooks, Paul Gueguen, Myriam Hofer, Adhideb Ghosh, Ramon Staeger, Prachi Shukla, Julia Martinez Gomez et al. · 2026 · Research Square
  46. ERBB fusions in Spitz neoplasms, expanding the spectrum of Spitz-associated genomic fusions
    Jonathan Braat, Lindsay Jeanne Holic, Nithya Sai Trichy, Shantel Olivares, Pedram Gerami · 2026 · Pathology
  47. Membrane PI(4,5)P 2 and ErbB2 abundance regulate ErbB receptor oligomerization and kinase activation
    Mitsuhiro Abe, Masataka Yanagawa, Yasushi Sako · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  48. Weak association of pathogenic ERBB4 variants with amyotrophic lateral sclerosis
    Pei-Shan Wang, Sheng-Mei Zou, Qiao Wei, Zhi-Ying Wu, Hong‐Fu Li · 2026 · Neurodegenerative Disease Management
  49. BindingDB Entry 50001836: Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening.
    BindingDB · 2020 · UC San Diego
  50. Melanoma of the Scalp Harboring a Novel AGFG1 :: ERBB4 Fusion: A Case Report With Clinicopathologic and Genomic Characterization
    Xu Cao, Hong Yu, Kenneth L. Muldrew, Rachel E. Johnson, Li Liang, Ying Pei, Yve Huttenbach, C. Cameron Yin, Songlin Zhang · 2026 · Genes Chromosomes and Cancer
  51. Targeting Apoptotic Pathways in Melanoma
    Peter Hersey, Xu Dong Zhang · 2011 · Springer eBooks
  52. Predictive Biomarkers as a Guide to Future Therapy Selection in Melanoma
    Thomas Frank Gajewski · 2011 · Springer eBooks