Genome partitioning of genetic variation for complex traits using common SNPs
Yang, Jian, Manolio, Teri A, Pasquale, Louis R, Boerwinkle, Eric, Caporaso, Neil, Cunningham, Julie M, de Andrade, Mariza, Feenstra, Bjarke +16 more·2011·Nature Genetics
DOI 10.1038/ng.823
Cited by (892)
Items 701–800 of 892
- Genetics of Human ObesityDavid Albuquerque, Licínio Manco, Clévio Nóbrega · 2015 · Springer eBooks
- Avian Population Studies in the Genomic EraArild Husby, S. Eryn McFarlane, Anna Qvarnström · 2019 · Springer eBooks
- The genetic architecture of bipolar disorder: Entering the road of discoveriesOlav Bjerkehagen Smeland, Andreas J. Forstner, Alexander W. Charney, Eli A. Stahl, Ole A. Andreassen · 2019 · Elsevier eBooks
- Predicting phenotypes of beef eating quality traitsMehrnush Forutan, Andrew Lynn, Hassan Aliloo, Sam Clark, P. McGilchrist, Rod Polkinghorne, Ben J. Hayes · 2023 · Frontiers in Genetics
- Kernel Bioassay Evaluation of Maize Ear Rot and Genome-Wide Association Analysis for Identifying Genetic Loci Associated with Resistance to Fusarium graminearum InfectionJihai Zhang, Haoya Shi, Yong Shun Yang, Cheng Zeng, Zheyi Jia, Tieli Ma, Mengyang Wu, Juan Du, Ning Huang, Guangtang Pan et al. · 2023 · Journal of Fungi
- Genetic variation within a stick-insect species associated with community-level traitsMarion Sinclair‐Waters, Laura S. Zamorano, Zachariah Gompert, Tom Parchman, Venera I. Tyukmaeva, David P. Hopkins, Patrik Nosil · 2024 · Journal of Evolutionary Biology
- Genetic modulation of lncPSMB1 confers non-syndromic cleft lip with or without cleft palate susceptibility by promoting cell apoptosisXiaofeng Li, Yue Gao, Tingting Cheng, Junyan Lin, Shu Lou, Lin Wang, Congbo Mi, Xu Ding, Mulong Du, Yongchu Pan · 2025 · Communications Biology
- Heritability Estimated Using 50K SNPs Indicates Missing Heritability Problem in Holstein BreedingDonghyun Shin, Kyoung-Do Park, Sojoeng Ka, Heebal Kim, Kwang‐Hyun Cho · 2015 · Genomics & Informatics
- Molecular genetic approaches to dissect complex behaviors in zebrafishJiale Xu, Su Guo · 2020 · Elsevier eBooks
- Whole-Genome Pathway Analysis on 132,497 Individuals Identifies Novel Gene-Sets Associated with Body Mass IndexMatthew A. Simonson, Matthew B. McQueen, Matthew C. Keller · 2014 · PLoS ONE
- Evaluation of an ensemble of genetic models for prediction of a quantitative traitJacqueline N. Milton, Martin H. Steinberg, Paola Sebastiani B · 2015 · Frontiers in Genetics
- Land ahoy? Navigating the genomic landscape of speciation while avoiding shipwreckAnja M. Westram, Mark Ravinet · 2017 · Journal of Evolutionary Biology
- The preventable burden of work-related ill-healthPierluigi Cocco, Raymond M Agius · 2018 · Occupational Medicine
- A multiplex SNP genotyping by allele‐specificspecific PCR based on stem‐loop and universal fluorescent primers of Chr1daxin miceMaochun Wang, Fuyi Xu, Ke Chen, Xiaoning Li, Kai Li, Yuxun Zhou, Junhua Xiao · 2019 · Electrophoresis
- Functional Annotations of Single-Nucleotide Polymorphism (SNP)-Based and Gene-Based Genome-Wide Association Studies Show Genes Affecting Keratitis SusceptibilityYue Xu, Xiaolin Yang, Xiaolong Yang, Ya-Ru Ren, Xin-Yu Zhuang, Lei Zhang, Xiao-Feng Zhang · 2020 · Medical Science Monitor
- Future Directions in Genetics of Psychiatric DisordersNaomi R. Wray, Enda M. Byrne, Sven Stringer, Bryan J. Mowry · 2014 · Springer eBooks
- Multidimensional Heritability Analysis of Neuroanatomical ShapeTian Ge, Martin Reuter, Anderson M. Winkler, Avram J. Holmes, Phil H. Lee, Lee Sean Tirrell, Joshua L. Roffman, Randy L. Buckner, Jordan W. Smoller, Mert Rory Sabuncu · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
- Large-scale neuroimaging and genetic study reveals genetic architecture of brain white matter microstructureBingxin Zhao, Jingwen Zhang, Joseph G. Ibrahim, Rebecca Santelli, Yun Li, Tengfei Li, Yue Shan, Ziliang Zhu, Fan Zhou, Huiling Liao et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Animal models with group-specific additive genetic variances: extending genetic group modelsStefanie Muff, Alina K. Niskanen, Dilan Saatoglu, Lukas F. Keller, Henrik Jensen · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- The genetic architecture of neurodevelopmental disordersKevin J. Mitchell · 2014 · bioRxiv (Cold Spring Harbor Laboratory)
- Showcasing the Variety of Biosocial and Evolutionary Approaches in Sociology: Introduction to the Special IssueSebastian Schnettler, Johannes J. Huinink · 2024 · KZfSS Kölner Zeitschrift für Soziologie und Sozialpsychologie
- Quantitative system driftCarl Veller, Pavitra Muralidhar · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effectsCarolina G Downie, Poojan Shrestha, Samson Okello, Mohammad Yaser, Harold Lee, Yujie Wang, Mohanraj Krishnan, Hung‐Hsin Chen, Anne E. Justice, Geetha Chittoor et al. · 2025 · Human Genetics and Genomics Advances
- Quantitative system driftCarl Veller, Pavitra Muralidhar · 2026 · Proceedings of the National Academy of Sciences
- Genetic prediction of complex traits: integrating infinitesimal and marked genetic effectsClément Carré, Fabrice Gamboa, David Cros, John Michael Hickey, Gregor Gorjanc, Eduardo Manfredi · 2013 · Genetica
- Improving Imputation Accuracy by Inferring Causal Variants in Genetic StudiesYue Wu, Farhad Hormozdiari, Jong Wha J. Joo, Eleazar Eskin · 2017 · Lecture notes in computer science
- Estimating heritability of glycaemic response to metformin using nationwide electronic health records and population-sized pedigreeIris N. Kalka, Amir Gavrieli, Smadar Shilo, Hagai Rossman, Nitzan Shalom Artzi, Nancy‐Sarah Yacovzada, Eran Segal · 2021 · Communications Medicine
- Trans-Acting Genotypes Associated with mRNA Expression Affect Metabolic and Thermal Tolerance TraitsMelissa K. Drown, Marjorie F. Oleksiak, Douglas L. Crawford · 2023 · Genome Biology and Evolution
- A Genetic Analysis of Current Medication Use in the UK BiobankPalle Duun Rohde · 2024 · Journal of Personalized Medicine
- GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene DiscoveryLucas C. Perry, Nicolas Chevalier, Michelle Luciano · 2025 · Behavior Genetics
- Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT intervalDevyn Mitchell, Rizwan Ullah, Loren R. Vanags, Alex Shen, Luke Jones, William Morris, Matthew J. O’Neill, Giovanni Davogustto, Christian M. Shaffer, Dan M. Roden et al. · 2025 · Stem Cell Research
- From Rare Mutations to Normal Variation: Genetic Association Study of Mathematical, Spatial, and General Cognitive AbilitiesMaja Rodic, Kaili Rimfeld, Darya Gaysina, Yulia V. Kovas · 2018 · Psychology in Russia State of Art
- Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery diseaseLerato E Magosi, Anuj Goel, Jemma C. Hopewell, Martin Farrall · 2019 · Bioinformatics
- Discovery and Characterization of Cancer Genetic Susceptibility AllelesStephen Jacob Chanock, Elaine A. Ostrander · 2014 · Elsevier eBooks
- Natural Selection and Neuropsychiatric DiseaseMark J. Daly, Elise Robinson, Benjamin M. Neale · 2016 · Elsevier eBooks
- Robust inference of genetic architecture in mapping studiesJon Slate · 2017 · Molecular Ecology
- Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levelsJessica Kiri Dennis, Alejandra Medina-Rivera, Vinh Trương, Lina Antounians, Nora Zwingerman, Giovana Carrasco, Lisa J. Strug, Philip Stephen Wells, David‐Alexandre Trégouët, Pierre‐Emmanuel Morange et al. · 2017 · Genetic Epidemiology
- Big Genome Data Classification with Random Forests Using VariantSparkA. Shobana Devi, G. Maragatham · 2018 · Lecture notes on data engineering and communications technologies
- Improved estimation of functional enrichment in SNP heritability using feasible generalized least squaresZewei Xiong, TQ Thach, Yan Zhang, Pak Chung Sham · 2024 · Human Genetics and Genomics Advances
- Genome-Wide Association Studies of ObesityÅsa K. Hedman, Cecilia M. Lindgren, Mark I. McCarthy · 2013 · Springer eBooks
- Pharmacogenomics of Ventricular Conduction in Multi-Ethnic PopulationsAmanda A. Seyerle · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
- Incorporation of Trait-Specific Genetic Information into Genomic Prediction ModelsShaolei Shi, Zhe Zhang, Bingjie Li, Shengli Zhang, Lingzhao Fang · 2022 · Methods in molecular biology
- GPA: A statistical approach to prioritizing GWAS results by integrating pleiotropy information and annotation dataDongjun Chung, Can Yang, Cong Li, Joel E. Gelernter, Hongyu Zhao · 2014 · arXiv (Cornell University)
- Accurate genetic profiling of anthropometric traits using a big data approachOriol Canela‐Xandri, Konrad Rawlik, John Arthur Woolliams, Albert Tenesa · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
- An efficient group test for genetic markers that handles confoundingJennifer Listgarten, Christoph Lippert, David E. Heckerman · 2012 · arXiv (Cornell University)
- Testing implications of the polygenic model for the genetic analysis of loci identified through genome-wide associationWenyu Zhang, R. Guy Reeves, Diethard Tautz · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- On the genetic architecture of rapidly adapting and convergent life history traits in guppiesJames R. Whiting, Josephine R. Paris, Paul J. Parsons, Sophie Matthews, Yuridia Reynoso, Kimberly A. Hughes, David N. Reznick, Bonnie A. Fraser · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Host Genetics Underlying Pathological Outcomes to Mycobacterium Avium Subsp. Paratuberculosis Infection is Governed by Distinct Genetic VariantsMaría Canive, Gerard Badia-Bringué, Patricia Vázquez, Óscar González-Recio, Almudena Fernández, Joseba M. Garrido, Ramón Antonio Juste, Marta Alonso‐Hearn · 2021 · Research Square
- Retraction Note: Detection and replication of epistasis influencing transcription in humansGibran Hemani, Konstantin Shakhbazov, Harm-Jan Westra, Tõnu Esko, Anjali K. Henders, Allan F. McRae, Jian Yang, Greg C. Gibson, Nicholas G. Martin, Andres Metspalu et al. · 2021 · Nature · Retracted
- Plant genotype-specific modulation of Clonostachys rosea -mediated biocontrol of septoria tritici blotch disease on wheatSidhant Chaudhary, Mustafa Zakieh, Mukesh K. Dubey, Dan Funck Jensen, Laura J. Grenville‐Briggs, Aakash Chawade, Magnus Karlsson · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Functional Annotation of Bipolar Disorder 2 Risk Location Implicates Novel Susceptibility GenesGüneş Şayan Can, Ebru Bakır, Yavuz Oktay · 2025 · Neuropsychobiology
- Genomic variance partitioning of carcass and meat quality traits in Angus beef cattleHasan Baneh, Nikolay P. Elatkin, Laurent Gentzbittel · 2025 · Frontiers in Veterinary Science
- A ayesian egularized and nnotation- formed ntegrative nalysis of ognition (BRAINIAC)Rong Zablocki, Bohan Xu, Chun Chieh Fan, Wesley Kurt Thompson · 2025 · Developmental Cognitive Neuroscience
- Polygenic Scores of Executive Function Provide Limited Support for Genetic Confounding With Socio‐Economic MeasuresLucas C. Perry, Nicolas Chevalier, Michelle Luciano · 2025 · Genes Brain & Behavior
- Genomic assessment of reproduction traits in Holstein dairy cattle across 3 lactations using additive genetic models and post hoc random forest analysisLeopold Schwarz, Johannes Heise, Jörn Bennewitz, Georg Thaller, Jens Tetens · 2025 · Journal of Dairy Science
- Effects of testosterone on gene expression in males and females across 40 human tissuesEvans K. Cheruiyot, Zhihong Zhu, Allan F. McRae · 2026 · Scientific Reports
- Genomic prediction using a cost-effective mid-density SNP platform in spring wheatYaotian Gao, Guriqbal Singh Dhillon, Amandeep Kaur, Pabitra Joshi, Justin Wheeler, Jianli Chen · 2026 · Frontiers in Plant Science
- The Diversity of Quantitative Trait Loci in Yeast Sporulation EfficiencyKimberly Lorenz · 2013 · Open Scholarship Institutional Repository (Washington University in St. Louis)
- Personalized Medicine and Cardiovascular Disease: From Genome to BedsideStephen Pan, Frederick E. Dewey, Marco Valentin Perez, Joshua W. Knowles, Rong Chen, Atul Janardhan Butte, Euan Angus Ashley · 2011 · Current Cardiovascular Risk Reports
- Genetics of Drug Response in DiabetesEwan R. Pearson, José C. Florez · 2014 · Frontiers in diabetes
- Reflections on the Field of Human Genetics: A Call for Increased Disease Genetics TheorySteven J. Schrodi · 2016 · Frontiers in Genetics
- Studying Rare Genetic Syndromes as a Method of Investigating Aetiology of Normal Variation in Educationally Relevant TraitsMaja Rodic, Darya Gaysina, Sophia J. Docherty, Sergey B. Malykh, Kaili Rimfeld, Robert J. Plomin, Yulia V. Kovas · 2016 · Palgrave Macmillan UK eBooks
- Across-breed genomic prediction for body weight in Siberian cattle populationsBurak Karacaören · 2020 · TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES
- Exciting Research in the Field of Sexual Psychopharmacology: Treating Patients with Inside InformationPaddy K.C. Janssen · 2021 · Springer eBooks
- Genetics of bipolar disorderKevin Sean O’Connell, Olav Bjerkehagen Smeland, Ole A. Andreassen · 2022 · Elsevier eBooks
- Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East AsiansYounghwa Lee, Jun Young Park, Jang Jae Lee, Jungsoo Gim, Ah Ra, Jinyeon Jo, Juhong Park, Kangjin Kim, Kyungtaek Park, Heejin Jin et al. · 2023 · Cerebral Cortex
- The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetesMahmoud Amiri Roudbar, Seyed Milad Vahedi, Jin Jin, Mina Jahangiri, Hossein Lanjanian, Danial Habibi, Sajedeh Masjoudi, Parisa Riahi, Sahand Tehrani Fateh, Farideh Neshati et al. · 2024 · Human Genomics
- On the genetic origins of phenotypes in genome-wide association studies: the SAFE-h2 tool for exploring additive and non-additive allelic effectsBehrooz Darbani, Mogens Nicolaisen · 2026 · BMC Bioinformatics
- Omnigenic Model: The Evidence from Neurodegenerative DiseasesLibing Shen, Qili Shi · 2017 · Journal of Psychiatry and Brain Science
- “Arte et Labore”—A Blackburn Rovers fan's legacy in human complex trait geneticsPeter M. Visscher, Naomi R. Wray, Chris Haley · 2019 · Journal of Animal Breeding and Genetics
- Arvelig fedme - hvor mye vekt skal man legge på gener?K. Øvretveit · 2020 · Norsk tidsskrift for ernæring
- Questions, Behavior, and Responsibility in Precision MedicineJennifer L. Hall · 2017 · Circulation
- Discovery of genetic determinants for refractive errorRupal L. Shah · 2018 · ORCA Online Research @Cardiff (Cardiff University)
- Bayesian Mendelian Randomization identifies disease causing proteins via pedigree data, partially observed exposures and correlated instrumentsTeresa Fazia, Leonardo Egidi, Burcu Ayoglu, Ashley Harris Beecham, Pier Paolo Bitti, Anna Ticca, Jacob L. McCauley, Peter Nilsson, Carlo Berzuini, Luisa Bernardinelli · 2019 · arXiv (Cornell University)
- Testing the omnigenic model for a behavioral trait in Drosophila melanogasterZhang, W., Reeves, R., Diethard Tautz · 2019 · MPG.PuRe (Max Planck Society)
- Complex Multifactorial Genetic DiseasesDaniel P. Howrigan, Nancy William, Todd M. Darlington · 2018 · Wiley eBooks
- Disease Risk ModelsAllison Meisner, Nilanjan Chatterjee · 2019 · Wiley eBooks
- Rapid polygenic selection generates fine spatial structure among ecological niches in a well-mixed populationMoritz A. Ehrlich, Dominique N. Wagner, Marjorie F. Oleksiak, Douglas L. Crawford · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- The genetic architecture of medication-usePalle Duun Rohde, Peter Sørensen, Mette Nyegaard · 2020 · medRxiv
- DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responsesXueyi Shen, Doretta Caramaschi, Mark J. Adams, Rosie May Walker, Josine L. Min, Alex S. F. Kwong, Gibran Hemani, Miruna C. Barbu, Heather Clare Whalley, Sarah E. Harris et al. · 2021 · medRxiv
- Role of genomic variants in the response to biologics targeting common autoimmune disordersGordana Lenert · 2016
- Why are GWASs limp about the X chromosome?Christopher Ian Amos, Ivan P. Gorlov · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity GeneJanine F. Felix, Struan F.A. Grant · 2023 · Diabetes
- The accuracy of polygenic score models for anthropometric traits and Type II Diabetes in the Native Hawaiian PopulationYing-Chu Lo, T. Chan, Soyoung Jeon, G. Maskarinec, K. Taparra, Nathan Nakatsuka, Ming-Rui Yu, Chia-Yen Chen, Yen-Feng Lin, L. Wilkens et al. · 2023 · medRxiv
- Étude des bases génétiques et physiologiques du besoin en azote des levures Saccharomyces cerevisiae en fermentation alcooliqueClaire Brice · 2013
- Understanding Risk Aversion in Older Americans: New Approaches Using Genetic DataAmal Harrati · 2014 · eScholarship (California Digital Library)
- THE NATURAL AND ORTHOGONAL INTERACTION (NOIA) MODELS FOR QUANTITATIVE TRAITS (QTs) AND COMPLEX DISEASESFeifei Xiao · 2013 · Digital Commons-TMC (Texas Medical Center)
- Genome-Wide Analyses of HIV-1 Host GeneticsKimberly Pelak · 2012 · DukeSpace (Duke University)
- Obesity, physical activity and cardiorespiratory fitness in young adulthood : Studies in Finnish twinsLinda Mustelin · 2012 · Työväentutkimus Vuosikirja
- Genome-Wide Association Studies of Human Growth TraitsMichael N. Weedon · 2013 · Nestlé Nutrition Institute Workshop series
- Dietary factors, obesity and serum lipoprotein profile : A nutritional epidemiological study in young adult twinsLeonie Helen Bogl · 2014 · Työväentutkimus Vuosikirja
- Effective number of genes and accuracy of genomic evaluationsEduardo C. G. Pimentel, Henner Simianer, Sven König · 2011 · Bulletin - International Bull Evaluation Service/Interbull bulletin
- The aetiology of the number sense and its relationship with mathematics : a genetically sensitive investigationMaria Grazia Tosto · 2012 · Goldsmiths (University of London)
- Statistical Methods in Genetic and Molecular Epidemiology and Their Application in Studies with Metabolic PhenotypesChristian Gieger · 2012 · Springer eBooks
- La cultura empresarial y el impacto en el comportamiento de los trabajadoresPedraza Acosta, Katherine Andrea · 2013
- Gene and Gene-Set Analysis for Genome-Wide Association StudiesInti Pedroso · 2013 · arXiv (Cornell University)
- The molecular basis of early onset cardiovascular diseaseSuthesh Sivapalaratnam · 2012 · UvA-DARE (University of Amsterdam)
- Post-GWAS AnalysesDaniel O. Stram · 2013 · Statistics for biology and health
- Between Circulating Fibrinogen and Cardiovascular Disease Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 SubjectsDorret Irene Boomsma, Jie Yao, Nancy S. Jenny, Talin Haritunians, Barbara McKnight, G. Uitterlinden, Oscar H. Franco, Albert Hofman D, Jenny van Dongen, Rona J. Strawbridge et al. · 2013
- Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and HairMorphology Data, Gitta H. Lubke, Charles Laurin, Raymond Kenney Walters, Nicholas Eriksson, Pirro G. Hysi, Tim D. Spector, Grant W. Montgomery, Martin Ng, Sarah Elizabeth Medland et al. · 2013