Genome partitioning of genetic variation for complex traits using common SNPs

Yang, Jian, Manolio, Teri A, Pasquale, Louis R, Boerwinkle, Eric, Caporaso, Neil, Cunningham, Julie M, de Andrade, Mariza, Feenstra, Bjarke +16 more·2011·Nature Genetics

Cited by (892)

Items 801–892 of 892

  1. Genetic architecture of complex disease in humans: a cross-population exploration
    Martínez Marigorta, Urko · 2012 · Repositori digital de la UPF (Universitat Pompeu Fabra)
  2. Integrating longitudinal twin research and measured genetic variation to test developmental theories of behavioral disinhibition and adolescent substance use.
    Scott I. Vrieze · 2012 · University of Minnesota Digital Conservancy (University of Minnesota)
  3. NEXT GENERATION SEQUENCING DATA IN BOVINE: QUALITY CONTROL, IMPUTATION, AND APPLICATION
    Steven G. Larmer · 2016 · The Atrium (University of Guelph)
  4. The Search is On for Missing Heritability -- and Missing "Environmentality" -- of Personality: A Developmental Approach
    Lindsay K. Matteson · 2016 · University of Minnesota Digital Conservancy (University of Minnesota)
  5. Accurate genetic profiling of anthropometric traits using a
    Oriol Canela‐Xandri, Konrad Rawlik, John Arthur Woolliams, Albert Tenesa · 2015
  6. Detecting Polygenic Evolution: Problems, Pitfalls, and
    Promises Wellenreuther, Bengt Hansson · 2016
  7. Introduction to statistical methods in genome-wide association studies
    Can Yang, Cong Li, Dongjun Chung, Mengjie Chen, Joel E. Gelernter, Hongyu Zhao · 2015 · Cambridge University Press eBooks
  8. Sparse Simultaneous Signal Detection With Applications in Genomics
    Julie Kobie · 2016 · ScholarlyCommons (University of Pennsylvania)
  9. and the Role of Rare Coding Variants in Type 2 Diabetes
    Kirk E. Lohmueller, Thomas Sparsø, Qibin Li, Ehm Astrid Andersson Galijatovic, Thorfinn Sand Korneliussen, Anders Albrechtsen, Karina Banasik, Niels Grarup, Ingileif B. Hallgrímsdóttir, Kristoffer Kiil et al. · 2013
  10. Epidemiology of Gait and Daily Functioning : The role of the nervous system
    Vincentius J.A. Verlinden · 2015 · EUR Research Repository (Erasmus University Rotterdam)
  11. Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies
    Yue Wu, Farhad Hormozdiari, Jong Wha J. Joo, Eleazar Eskin · 2018 · Journal of Computational Biology
  12. Functional genomics of the VNN1 gene
    Luke A. Diepeveen · 2013 · UWA Profiles and Research Repository (UWA)
  13. Improving Biological Understanding and Complex Trait Prediction by Integrating Prior Information in Genomic Feature Models
    Stefan McKinnon Edwards · 2014
  14. Einfluss verschiedener Genvarianten auf den Erfolg von Adipositastherapien
    Anna Mühlberger, Stephan Bischoff, Sandrine Louis · 2017 · Aktuelle Ernährungsmedizin
  15. Genetics of intracranial aneurysms and related diseases
    Femke N. G. van ’t Hof · 2017 · Utrecht University Repository (Utrecht University)
  16. A unifying framework for summary statistic imputation
    Yue Wu, Eleazar Eskin, Sriram Sankararaman · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  17. High-resolution regulatory maps connect cardiovascular risk variants to disease related pathways
    Örjan Åkerborg, Rapolas Spalinskas, Sailendra Pradhananga, Anandashankar Anil, Pontus Höjer, Flore-Anne Poujade, Lasse Folkersen, Per Olof Eriksson, Pelin Sahlén · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  18. Exploring the genetic architecture and the chromatin organisation of breast cancer
    Olivia C. Leavy · 2018 · LSHTM Research Online (London School of Hygiene and Tropical Medicine)
  19. The genetics and evolutionary dynamics of sexually antagonistic polymorphisms in Drosophila melanogaster
    Filip Ruzicka · 2018 · UCL Discovery (University College London)
  20. Association of Obesity with Health Care Costs: A Mendelian Randomization study
    Christoph F. Kurz, M. Laxy · 2019 · bioRxiv
  21. Host Genetic Characters of Acute Exacerbation of Chronic Hepatitis B (AECHB)
    Yuming Wang, Junqi Niu, Guohong Deng, Yingren Zhao · 2019 · Springer eBooks
  22. Statistical Methods for Large-scale Multiple Testing Problems
    Yu Gao · 2019 · UWSpace (University of Waterloo)
  23. Improving Genetic Association Analysis through Integration of Functional Annotations of the Human Genome
    Qiongshi Lu, Hongyu Zhao · 2019 · Wiley eBooks
  24. Variation in the heritability of child body mass index by obesogenic home environment
    Stephanie Schrempft, Cornelia H.M. van Jaarsveld, Abigail Fisher, Moritz Herle, Andrea Dominica Smith, Alison Fildes, Clare Heidi Llewellyn · 2019 · Yearbook of pediatric endocrinology
  25. Genetic influences on PTSD
    Kaitlin E. Bountress, Leslie Ann D. Brick, Shannon E. Cusack, Christina M. Sheerin, Nicole R. Nugent, Ananda B. Amstadter · 2020 · Elsevier eBooks
  26. Mendelian Randomization with Incomplete Exposure Data: a Bayesian Approach
    Teresa Fazia, Leonardo Egidi, Burcu Ayoglu, Ashley Harris Beecham, Pier Paolo Bitti, Anna Ticca, Hui Guo, Jacob L. McCauley, Peter Nilsson, Rosanna Asselta et al. · 2020 · arXiv (Cornell University)
  27. High heritability does not imply accurate prediction under the small additive effects hypothesis
    Arthur Frouin, Claire Dandine‐Roulland, Morgane Pierre‐Jean, Jean‐François Deleuze, Christophe Ambroise, Édith Le Floch · 2020 · arXiv (Cornell University)
  28. Complex Traits in Natural Populations
    Daniel L. Hartl · 2020 · Oxford University Press eBooks
  29. Use of whole-genome sequence data for genomic prediction across populations and species
    Biaty Raymond · 2020
  30. Variance Estimation and Confidence Intervals from High-dimensional Genome-wide Association Studies Through Misspecified Mixed Model Analysis
    Cecilia Dao, Jiming Jiang, Debashis Paul, Hongyu Zhao · 2021 · arXiv (Cornell University)
  31. What HaveWe Learned fromGWAS?
    Benjamin F. Voight · 2021 · Springer eBooks
  32. Investigating the mechanisms of ankylosing spondylitis-associated genetic variants
    Jessica Whyte · 2021 · Queensland University of Technology
  33. Combining twin-family designs with measured genetic variants to study the causes of epigenetic variation
    Camelia C. Minică, Michael Churton Neale, Dorret Irene Boomsma, Jenny van Dongen · 2021 · Elsevier eBooks
  34. Collagen fibril formation during development
    Raúl Fleischmajer, Jerome S. Perlish, Rupert Timpl, Bjorn Reino Olsen · 1987 · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)
  35. Precision Medicine: Pharmacogenetics and Pharmacogenomics of Osteoporosis
    Yasser M El Miedany · 2022 · Springer eBooks
  36. Diagnosis of Neurogenetic Disorders: Contribution of Next Generation Sequencing and Deep Phenotyping
    Alisdair McNeill · 2019 · MDPI eBooks
  37. Big fish, little fish: a multi-omics investigation of growth traits in silver trevally (Pseudocaranx georgianus – araara)
    Valenza-Troubat, Noémie · 2021
  38. Peer Review #3 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.1)"
    2018 · PeerJ
  39. Peer Review #3 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.2)"
    2018 · PeerJ
  40. Correction: Heritability and Genetic Correlations Explained by Common SNPs for Metabolic Syndrome Traits
    Shashaank Vattikuti, Juen Guo, Carson C. Chow · 2012 · PLoS Genetics
  41. Heritability
    Jeffrey C. Long · 2018 · The International Encyclopedia of Biological Anthropology
  42. Peer Review #2 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.1)"
    2018 · PeerJ
  43. Faculty Opinions recommendation of Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
    John I. Nürnberger · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  44. Faculty Opinions recommendation of Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
    Benjamin A. Raby, Angela J. Rogers · 2011 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  45. Peer Review #1 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.2)"
    2018 · PeerJ
  46. Faculty Opinions recommendation of Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
    Anne E. Kwitek · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  47. Peer Review #2 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.2)"
    2018 · PeerJ
  48. Faculty Opinions recommendation of Common DNA Variants Accurately Rank an Individual of Extreme Height.
    Joseph Lachance · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  49. In brief
    2011 · Nature Reviews Genetics
  50. Big fish, little fish: a multi-omics investigation of growth traits in silver trevally (Pseudocaranx georgianus – araara)
    Valenza-Troubat, Noémie · 2021
  51. Peer Review #1 of "Genomic analysis of morphometric traits in bighorn sheep using the Ovine Infinium® HD SNP BeadChip (v0.1)"
    2018 · PeerJ
  52. Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships
    Ronald de Vlaming, Eric A. W. Slob, Patrick J. F. Groenen, Cornelius A. Rietveld · 2022 · BMC Bioinformatics
  53. Selecting Chromosomes for Polygenic Traits: Algorithms and Complexity *
    Or Zuk · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  54. Estimation of genetic heritabilities of human traits in case–control studies
    Die Hu, Shuyue Chen, Hong Zhang · 2022 · Annals of Human Genetics
  55. Trans-Acting Genotypes Drive mRNA Expression Affecting Metabolic And Thermal Tolerance Traits
    Melissa K. Drown, Marjorie F. Oleksiak, Douglas L. Crawford · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  56. Data from Tumor Mutational Burden Is Polygenic and Genetically Associated with Complex Traits and Diseases
    Xiwei Sun, Angli Xue, Ting Qi, Dan Chen, Dandan Shi, Yang Wu, Zhili Zheng, Jian Zeng, Jian Yang · 2023
  57. Inheritance of a Single Trait
    Stevan J. Arnold · 2023
  58. Copy Number Variants and heritability estimates on UKBiobank data
    Jawad Boulahfa, Édith Le Floch, Morgane Pierre‐Jean, Jean‐François Deleuze, Claire Dandine‐Roulland · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Effect of testosterone on within-sex gene expression across 40 human tissues
    Evans K. Cheruiyot, Zhihong Zhu, Allan F. McRae · 2023 · Research Square
  60. Quantitative Genetics in Natural Populations
    Alastair James Wilson, Jocelyn Poissant · 2024 · Elsevier eBooks
  61. Exciting Research in the Field of Sexual Psychopharmacology: Treating Patients with Inside Information
    Paddy K.C. Janssen · 2024 · Springer eBooks
  62. Three Loci Affecting Variance of Body Mass Index in African Americans and Sub‐Saharan Africans
    Daniel Shriner, Amy R. Bentley, Ayo Priscille Doumatey, Jie Zhou, Guanjie Chen, Charles N. Rotimi, Adebowale Adeyemo · 2025 · Genetic Epidemiology
  63. Assessing the adaptative potential to temperature and precipitation along a steep environmental gradient in populations of European beech
    Mila Leonie Tost, Ourania Grigoriadou Zormpa, Selina Wilhelmi, Markus Mueller, Henning Wildhagen, Alexandru Lucian Curtu, Oliver Gailing · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  64. An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic
    Evelyn Jade, Mathew D. Littlejohn, Katie Eketone, Richard J. Spelman, Jessica Stapley, Anna W. Santure · 2025 · Journal of Animal Breeding and Genetics
  65. Connecting genes to physiology: the first 25 years of Physiological Genomics
    Bina Joe, Allen W. Cowley, Michael R. Garrett, Alison Jessica Kriegel, Jeremy W. Prokop, Elaine C. Lee, Oluwatosin M. Akinola, Hilary A. Coller · 2025 · Physiological Genomics
  66. Kinship estimation bias carries over to heritability estimation bias using variance components
    Zhuoran Hou, Alejandro Ochoa · 2025 · Genetics
  67. Genetic determinants of cardiovascular disease : heritability and genetic risk score
    Elias Salfati · 2014 · theses.fr (ABES)
  68. Additional file 1 of A deterministic equation to predict the accuracy of multi-population genomic prediction with multiple genomic relationship matrices
    Biaty Raymond, Yvonne C. J. Wientjes, A.C. Bouwman, C. Schrooten, Veerkamp, Roel F. · 2020 · Figshare
  69. Additional file 1 of The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime
    Kathrin Anna Otte, Viola Nolte, François Mallard, Christian Schlötterer · 2021 · Figshare
  70. Epidemiology of Lung Function and Chronic Obstructive Pulmonary Disease
    Daan W. Loth · 2013 · RePub (Erasmus University Rotterdam)
  71. Additional file 3 of The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime
    Kathrin Anna Otte, Viola Nolte, François Mallard, Christian Schlötterer · 2021 · Figshare
  72. Additional file 1 of Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships
    Ronald de Vlaming, Slob, Eric A. W., Patrick J. F. Groenen, Cornelius A. Rietveld · 2022 · Figshare
  73. Additional file 2 of Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism
    Evin M. Padhi, Tristan J. Hayeck, Cheng, Zhang, Sumantra Chatterjee, Brandon J. Mannion, Marta S. Byrska‐Bishop, Marjolaine Willems, Lucile Pinson, Sylvia Redon, Caroline Bénech et al. · 2021 · Figshare
  74. Additional file 1 of Evaluation of heritability partitioning approaches in livestock populations
    Can Yuan, José Luis Gualdrón Duarte, Haruko Takeda, Michel Georges, Tom Druet · 2024 · Figshare
  75. Additional file 2 of Evaluation of heritability partitioning approaches in livestock populations
    Can Yuan, José Luis Gualdrón Duarte, Haruko Takeda, Michel Georges, Tom Druet · 2024 · Figshare
  76. Universal Inference for Variance Components
    Yiqiao Zhang, Karl Oskar Ekvall, Aaron J. Molstad · 2026 · Stat
  77. A time-to-event heritability framework for inferring the genetic architecture of longitudinal traits
    Kodi Taraszka, Sriram Sankararaman, Alexander Gusev · 2026 · medRxiv
  78. RELN biallelic variant as a candidate risk factor in a consanguineous Pakistani family with bipolar disorder and clinical heterogeneity
    Aisha Nasir Hashmi, Ricardo Harripaul, Tahir Muhammad, Benjamin Lowther, Anna Mikhailov, Zehra Agha, Raheel Qamar, John B. Vincent, Maleeha Azam · 2026 · Journal of Affective Disorders
  79. Genetic regulatory landscape of gene expression during leaf and stem development in common tobacco
    Mou Yin, Zhimeng Zhang, Yuexuan Hou, Yueying Wan, Qiaoling Luo, Chunqiong Wang, Xiaowei Zhang, Haowei Sun, Jie Long, Jieyun Cai et al. · 2026 · Journal of genetics and genomics/Journal of Genetics and Genomics
  80. Host Prior Exposure Augments Gene Expression Heterogeneity of Both Host and Pathogen During In Vivo Infection
    Anna A. Pérez‐Umphrey, Jeremy Miller, E. R. Tulman, Jesse Garrett-Larsen, Michal Vinkler, Kate E. Langwig, Steven J. Geary, James Stephen Adelman, Dana Michelle Hawley · 2026 · Molecular Ecology
  81. Role of bone microarchitecture and hereditary determinants of bone fragility
    Hoda Abdelmohsen Ali Mohamed Nagy · 2013
  82. Assessing evolutionary potential in the wild : biologging technologies meet genome-wide data in a roe deer population
    Laura Gervais · 2020
  83. Caenorhabditis becei recombinant inbred lines (beRILs) reveal the scope of heritable variation within a gonochoristic nematode population
    Tom Parée, Jose Salome Correa, Derin Çağlar, Jacqueline L. Jackson, Arielle Martel, Tuc H. M. Nguyen, Sophie Vallance, Matthew V. Rockman · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  84. Population Differentiation and Polygenic Selection in the Finnish Ayrshire Cows Selected on Genomic Information
    Katri Sarviaho, Minna Koivula, Terhi Iso‐Touru, Pekka Uimari, Katja Martikainen · 2026 · Journal of Animal Breeding and Genetics
  85. Variation in cocaine responses across genetically diverse mouse strains
    Malia Pollock, AbdulRahman Abbas, Hien M. Bui, Jay-Ho Chung, Yanchao Dai, Jack DiCola, Levi Goldberg, Savanna Hale, Carter Joyce, Emily Rubio et al. · 2026 · Psychopharmacology
  86. Anthropometric and cardio-metabolic trait variation and genetic associations in sub-Saharan Africa
    Matthew E.B. Hansen, Ujani Hazra, Michelle Kim, Srilakshmi M. Raj, Shaohua Fan, William R. Beggs, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Thomas Nyambo, Dawit Wolde Meskel et al. · 2026 · The American Journal of Human Genetics
  87. A genome-wide association study in rice landraces of North-East India for brown spot resistance
    Parinda Barua, Sunita Munda, Munmi Phukon, Amrendra Kumar, R. Sruthi, Jyoti Lekha Borah, Milon Jyoti Konwar, Ashok Bhattacharya, Sanjay Kumar Chetia · 2026 · Heliyon
  88. Genome‐Wide Association Study in European Beech ( Fagus sylvatica L.) for Drought Stress Related Traits
    Mila Leonie Tost, Ourania Grigoriadou Zormpa, Selina Wilhelmi, Timothy M. Beissinger, Mehdi Ben-Targem, Markus Mueller, Henning Wildhagen, Alexandru Lucian Curtu, Oliver Gailing · 2026 · Physiologia Plantarum
  89. Both twin and molecular genetic models indicate genetic confounding in the relationship between executive function, socioeconomic status, and parenting in middle childhood
    Lucas C. Perry, Nicolas Chevalier, Michelle Luciano · 2026 · Child Development
  90. Data from: Estimating quantitative genetic parameters in wild populations: a comparison of pedigree and genomic approaches
    Camillo Bérénos, Philip A. Ellis, Jill G. Pilkington, Josephine M. Pemberton · 2014 · Data Archiving and Networked Services (DANS)
  91. Genome-wide association study and haplotype characterization of bacterial kidney disease (BKD) resistance in Atlantic salmon (Salmo salar) across two generations
    Angela Astudillo, Ross Houston, Jean P. Lhorente, Baltasar Garcia · 2026 · Frontiers in Genetics
  92. Genetic Contribution: Common Forms of Obesity
    David Albuquerque, Clévio Nóbrega · 2014 · Springer eBooks