Essential role of limiting telomeres in the pathogenesis of Werner syndrome

Chang, Sandy, Multani, Asha S, Cabrera, Noelia G, Naylor, Maria L, Laud, Purnima, Lombard, David, Pathak, Sen, Guarente, Leonard +1 more·2004·Nature Genetics

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  23. Werner Syndrome, Telomeres, and Stress Signaling: Implications for Future Therapies?
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  28. Role of RecQ Helicases in Nuclear DNA Repair and Telomere Maintenance
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  29. Regulation of WRN Function by Acetylation and SIRT1-Mediated Deacetylation in Response to DNA Damage: A Dissertation
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  30. GENOTOXIN-INDUCED ACETYLATION OF THE WERNER SYNDROME PROTEIN (WRN) AND EFFECT ON ITS DNA METABOLIC FUNCTION
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  31. Mechanisms of Telomere Protection and Deprotection in Human Cells
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  32. Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy
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  33. Utilization of Werner syndrome mouse model in studying premature aging and tumor
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  34. Telomere Biology and Cardiovascular Disease
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  35. Initiation of Genomic Instability, Cellular Senescence, and Organismal Aging by Dysfunctional Telomeres
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  41. MUTAGENIC POTENTIAL OF TELOMERIC REPEATS AND THE ROLE OF WERNER SYNDROME HELICASE PROTEIN IN FACILITATING TELOMERIC DNA REPLICATION
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  55. Le rôle de l'oncoprotéine INT6 dans la maintenance des télomères
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  56. Mechanisms of replicative senescence in Werner's syndrome cells
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  57. Processing of Alternative DNA Structures in the Human Telomere
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  59. Rôle de la protéine TRF2 et de ses partenaires dans la recombinaison des télomères humains
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  62. DNA Polymerase Gamma Mutations in Male Infertility and Ageing
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