Essential role of limiting telomeres in the pathogenesis of Werner syndrome

Cited by (462)

Items 201–300 of 462

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    Thong Luong, Kara Anne Bernstein · 2021 · Genes
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    Li Hu, Chanjuan Dong, Zhe Wang, Shengyuan He, Yiwen Yang, Meiting Zi, Huiqin Li, Yanghuan Zhang, Chuanjie Chen, Runzi Zheng et al. · 2023 · Aging Cell
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    Sofie Lautrup, Domenica Caponio, Hoi‐Hung Cheung, Cláudia Piccoli, Tinna Stevnsner, Wai‐Yee Chan, Evandro Fei Fang · 2019 · Biogerontology
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    Takafumi Ishida, Mari Ishida, Satoshi Tashiro, Masao Yoshizumi, Yasuki Kihara · 2013 · Circulation Journal
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    Gregory A. Sowd, Ming Lei, Patricia Lynn Opresko · 2008 · Nucleic Acids Research
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    Antonio Paolo Beltrami, Daniela Cesselli, Carlo Alberto Beltrami · 2010 · Pharmacology & Therapeutics
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  21. Different Mechanisms of Longevity in Long-Lived Mouse and Caenorhabditis elegans Mutants Revealed by Statistical Analysis of Mortality Rates
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  23. Inhibition of Telomerase Activity Enhances Hyperthermia-Mediated Radiosensitization
    Manjula Agarwal, Shruti Pandita, Clayton R. Hunt, Arun K. Das Gupta, Xuan Yue, Saira Khan, RAJ KUMAR PANDITA, David Pratt, Jerry W. Shay, John‐Stephen Taylor et al. · 2008 · Cancer Research
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    Cheng, Wen-Hsing, Muftuoglu, Meltem, Bohr, Vilhelm A. · 2007 · Experimental Gerontology
  34. Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence
    Paula R. Barros, Tiago Januario Da Costa, Eliana Hiromi Akamine, Rita C. Tostes · 2021 · Frontiers in Aging
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  41. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
    Na Liu, Yu Yin, Haiying Wang, Zhongcheng Zhou, Xiaoyan Sheng, Haifeng Fu, Renpeng Guo, Hua Wang, Jiao Yang, Peng Gong et al. · 2019 · PLoS Genetics
  42. Evaluating Evidence for Aging
    Richard A. Miller · 2005 · Science
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  45. The expression signature of in vitro senescence resembles mouse but not human aging
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  46. Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan
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  47. WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome
    Yuyao Tian, Wuming Wang, Sofie Lautrup, Hui Zhao, Xiang Li, Patrick Wai Nok Law, Ngoc‐Duy Dinh, Evandro Fei Fang, Hoi‐Hung Cheung, Wai‐Yee Chan · 2022 · Nature Communications
  48. A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (Review)
    Masanobu Sugimoto · 2013 · International Journal of Molecular Medicine
  49. Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
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  50. Present Status and Future Challenges of New Therapeutic Targets in Preclinical Models of Stroke in Aged Animals with/without Comorbidities
    Aurel Popa‐Wagner, Daniela-Gabriela Glavan, Andrei Olaru, Denissa-Greta Olaru, Otilia Clara Mărgăritescu, Oana Sorina Tica, Roxana Surugiu, Raluca Elena Sandu · 2018 · International Journal of Molecular Sciences
  51. Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin
    Michel Lebel, Laurent Massip, Chantal Garand, Éric Thorin · 2010 · Annals of the New York Academy of Sciences
  52. Brief Report: Long-Term Functional Engraftment of Mesenchymal Progenitor Cells in a Mouse Model of Accelerated Aging
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  53. EXTENSION OF THE LIFE SPAN IN PATIENTS WITH WERNER SYNDROME
    Koutaro Yokote, Yasushi Saito · 2008 · Journal of the American Geriatrics Society
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    Mari Tokita, Scott R. Kennedy, Rosa Ana Risques, Stephen G. Chun, Colin C. Pritchard, Junko Oshima, Yan Liu, PETER K. BRYANT-GREENWOOD, Piri L. Welcsh, Raymond J. Monnat · 2016 · Scientific Reports
  55. WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1
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  56. Sgs1 RecQ Helicase Inhibits Survival of Saccharomyces cerevisiae Cells Lacking Telomerase and Homologous Recombination
    Julia Y. Lee, Jonathan L. Mogen, Alejandro Chavez, F Brad Johnson · 2008 · Journal of Biological Chemistry
  57. Response to Replication Stress and Maintenance of Genome Stability by WRN, the Werner Syndrome Protein
    David K. Orren, Amrita Machwe · 2024 · International Journal of Molecular Sciences
  58. Maintaining Genetic Integrity in Aging: A Zero Sum Game
    Yousin Suh, Jan Vijg · 2006 · Antioxidants and Redox Signaling
  59. Loss of p16Ink4a Function Rescues Cellular Senescence Induced by Telomere Dysfunction
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  60. Using RNA therapeutics to promote healthy aging
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    Johanna A. Smith, René Daniel · 2012 · Europe PMC (PubMed Central)
  62. Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts
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    Dana Larocca, Jieun Lee, Michael D. West, Ivan Labat, Hal Sternberg · 2021 · Genes
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    Kyoshiro Tsuge, Akira Shimamoto · 2022 · Genes
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