The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
Cretney, Erika, Xin, Annie, Shi, Wei, Minnich, Martina, Masson, Frederick, Miasari, Maria, Belz, Gabrielle T, Smyth, Gordon K +3 more·2011·Nature Immunology
DOI 10.1038/ni.2006
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- Elucidating T Cell Activation-Dependent Mechanisms for Bifurcation of Regulatory and Effector T Cell Differentiation by Multidimensional and Single-Cell AnalysisAlla Bradley, Tetsuo Hashimoto, Masahiro Ono · 2018 · Frontiers in Immunology
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