The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
Cretney, Erika, Xin, Annie, Shi, Wei, Minnich, Martina, Masson, Frederick, Miasari, Maria, Belz, Gabrielle T, Smyth, Gordon K +3 more·2011·Nature Immunology
DOI 10.1038/ni.2006
Cited by (605)
Items 401–500 of 605
- Macrophage-Specific MCPIP1/Regnase-1 Attenuates Kidney Ischemia-Reperfusion Injury by Shaping the Local Inflammatory Response and Tissue RegenerationAndrea Ribeiro, Ewelina Dobosz, Moritz Krill, Paulina Köhler, Marta Wadowska, Stefanie Steiger, Christoph Schmaderer, Joanna Kozieł, Maciej Lech · 2022 · Cells
- Implications of regulatory T cells in non-lymphoid tissue physiology and pathophysiologyDarya Malko, Tarek Elmzzahi, Marc Beyer · 2022 · Frontiers in Immunology
- Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activationErika Di Zazzo, Monica Rienzo, Amelia Casamassimi, Caterina De Rosa, Nicola Medici, Patrizia Gazzerro, Maurizio Bifulco, Ciro Abbondanza · 2023 · Journal of Translational Medicine
- IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenanceConstantin Schmidt, Aenne Harberts, Daniel Reimers, Tabea Bertram, Leonie Caroline Voß, Joanna Schmid, Niels Christian Lory, Michael Spohn, Friedrich Koch‐Nolte, Samuel Huber et al. · 2023 · Frontiers in Immunology
- miR-15/16 clusters restrict effector Treg cell differentiation and functionJiayi Dong, William J. Huth, Nimi Marcel, Ziyue Zhang, Ling-Li Lin, Li‐Fan Lu · 2023 · The Journal of Experimental Medicine
- Roles of IRF4 in various immune cells in systemic lupus erythematosusZe Xiu Xiao, Rongzhen Liang, Nancy J. Olsen, Song Guo Zheng · 2024 · International Immunopharmacology
- Inflammation‐associated genes: risks and benefits to Foxp3+ regulatory T‐cell functionRichard A. O’Connor, Stephen M. Anderton · 2015 · Immunology
- Blimp1: Driving Terminal Differentiation to a TAnnie Xin, Stephen L. Nutt, Gabrielle Therese Belz, Axel Kallies · 2011 · Advances in experimental medicine and biology
- PTD‐hFOXP3 protein acts as an immune regulator to convert human CD4+CD25−T cells to regulatory T‐like cellsXia Liu, Xun Xu, Xin Lin, Yuxiang Tian, Baoju Ji, Sheng Xia, Sanrong Xu, Qing Yin, Miaomiao Zhang, Zhijun Jiao et al. · 2012 · Journal of Cellular Biochemistry
- Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1Aline Yen Ling Wang, Charles Yuen Yung Loh, Shyi‐Jou Chen, Huang‐Kai Kao, Cheng‐Hung Lin, Sheng-Hao Chuang, Chin-Ming Lee, Huey‐Kang Sytwu, Fu‐Chan Wei · 2018 · Molecular Immunology
- Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-ҡB and AMPK1/mTOR PathwaysSandra Domingo, Cristina Solé, Teresa Moliné, Berta Ferrer Fábrega, Josefina Cortés-Hernández · 2021 · Biomedicines
- Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitisMarisol Alvarez-Martinez, Luke S. Cox, Claire F. Pearson, William J. Branchett, Probir Chakravarty, Xuemei Wu, Hubert Slawinski, Alaa Al‐Dibouni, Vasileios A. Samelis, Leona Gabryšová et al. · 2024 · Nature Immunology
- The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s ThyroiditisStana Tokić, Mario Štefanić, Ljubica Glavaš‐Obrovac, Sonja Jaman, Eva Novosadová, Jana Petřková, Zdeňka Navrátilová, Mirjana Suver Stević, Martin Petrek · 2016 · Mediators of Inflammation
- Sugars and fat – A healthy way to generate functional regulatory T cellsSarah S. Gabriel, Axel Kallies · 2016 · European Journal of Immunology
- MicroRNA-10a Negatively Regulates CD4+ T Cell IL-10 Production through Suppression of Blimp1Wenjing Yang, Liang Chen, Leiqi Xu, Anthony James Bilotta, Suxia Yao, Zhanju Liu, Yingzi Cong · 2021 · The Journal of Immunology
- The E-Id Axis Instructs Adaptive Versus Innate Lineage Cell Fate Choice and Instructs Regulatory T Cell DifferentiationReiko Hidaka, Kazuko Miyazaki, Masaki Miyazaki · 2022 · Frontiers in Immunology
- The atypical IκB protein IκBNS is important for Toll‐like receptor‐induced interleukin‐10 production in B cellsMinami Miura, Naoki Hasegawa, M. Noguchi, Kenkichi Sugimoto, Touma Maki · 2016 · Immunology
- Lenalidomide potentiates CD4+CD25+Treg-related suppression of lymphoma B-cell proliferationMonika Anna Grygorowicz, Ilona Sara Borycka, Eliza Nowak, Ewa Paszkiewicz‐Kozik, Grzegorz Rymkiewicz, Katarzyna Błachnio, Marzena Biernacka, Mateusz Bujko, Jan Andrzej Walewski, Sergiusz Markowicz · 2016 · Clinical and Experimental Medicine
- IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function modelChelisa Cardinez, Yuwei Hao, Kristy Kwong, Ainsley R. Davies, Morgan B. Downes, Nadia A. Roberts, Jason D. Price, Raquel A. Hernandez, Jessica Lovell, Rochna Chand et al. · 2024 · Nature Communications
- Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cellsMarie Boutet, Kenta Nishitani, Nicole Couturier, Piril Erler, Zheng Zhang, Anna Maria Militello, Marcelo Coutinho de Miranda, Emeline Barbieux, Erik Guillen, Jianmei Wu Leavenworth et al. · 2025 · Immunity
- Helios+ and RORγt+ Treg populations are differentially regulated by MHCII, CD28, and ICOS to shape the intestinal Treg poolElisa Cruz-Morales, Andrew P. Hart, Georgia M. Fossett, Terri M. Laufer · 2023 · Mucosal Immunology
- Understanding the Roles of the NF-κB Pathway in Regulatory T Cell Development, Differentiation and FunctionThomas S. Fulford, Darcy Ellis, Steve Gerondakis · 2015 · Progress in molecular biology and translational science
- Acute Lipopolysaccharide-Induced Inflammation Lowers IL-2R Signaling and the Proliferative Potential of Regulatory T CellsSunnie Hsiung, Alejandro Moro, Yuguang J. Ban, Xi Chen, Alicia Santos Savio, Rosmely Hernandez, Thomas R. Malek · 2020 · ImmunoHorizons
- Haploinsufficiency of interferon regulatory factor 4 strongly protects against autoimmune diabetes in NOD miceSatoru Akazawa, Masakazu Kobayashi, Genpei Kuriya, Ichiro Horie, Liping Yu, Hironori Yamasaki, Minoru Okita, Yuji Nagayama, T. Matsuyama, Masoud Akbari et al. · 2015 · Diabetologia
- Elevated Interferon Regulatory Factor 4 Levels in Patients with Allergic AsthmaChen Xia, Yadong Gao, Yang Jiong · 2012 · Journal of Asthma
- FOXP3 (in)stability and cancer immunotherapyKeywan Mortezaee · 2024 · Cytokine
- Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsetsAcacia N. Shouse, Alejandro V. Villarino, Thomas R. Malek · 2024 · iScience
- An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron MetabolismZengdi Zhang, Oscar Camilo Salgado, Bing Liu, Zahra Moazzami, Kristin Ann Hogquist, Michael A. Farrar, Hai‐Bin Ruan · 2022 · Frontiers in Immunology
- Potential and limitations of regulatory T-cell therapy in solid organ transplantationLerisa Govender, Manuel A. Pascual, Déla Golshayan · 2014 · Expert Review of Clinical Immunology
- Tolerogenic and immunogenic states of Langerhans cells are orchestrated by epidermal signals acting on a core maturation gene moduleMarta Ewa Polak, Harinder Singh · 2021 · BioEssays
- Anti-CD200R2, Anti-IL-9, Anti-IL-35, or Anti-TGF-β Abolishes Increased Graft Survival and Treg Induction Induced in Cromolyn-Treated CD200R1KO.CD200tg MiceReginald M. Gorczynski, Kai Yu, Zhiqi Chen · 2013 · Transplantation
- Metabolic Regulation of T Cell ImmunityPaolo Vignali, Joseph J. Barbi, Fan Pan · 2017 · Advances in experimental medicine and biology
- Skin as an immune organ and the site of biomimetic, non-invasive vaccinationAmla Chopra, Archi Gupta · 2022 · Medicine in Novel Technology and Devices
- Recirculation and Residency of T Cells and Tregs: Lessons Learnt in AnacapriSilvia Piconese, Silvia Campello, Ambra Natalini · 2020 · Frontiers in Immunology
- Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustionKeli Lee Hippen, Scott N. Furlan, Rahul Roychoudhuri, Ena Wang, Yigang Zhang, Mark J. Osborn, Sarah C. Merkel, Sophia Hani, Margaret L. MacMillan, Frank M. Cichocki et al. · 2021 · Cytotherapy
- Roles of the tacrolimus-dependent transcription factor IRF4 in acute rejection after liver transplantationTengqian Tang, Qian Lü, Xing Hua Yang, Xiangde Liu, Rui Liao, Yujun Zhang, Zhanyu Yang · 2015 · International Immunopharmacology
- c‐Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in miceThomas S. Fulford, Raelene J. Grumont, Rushika C. Wirasinha, Darcy Ellis, Adele A. Barugahare, Stephen J. Turner, Haroon Naeem, David Powell, Paul Lyons, Kenneth G. C. Smith et al. · 2021 · European Journal of Immunology
- Strength and Numbers: The Role of Affinity and Avidity in the ‘Quality’ of T Cell ToleranceSébastien This, Stefanie F. Valbon, Marie‐Ève Lebel, Heather J. Melichar · 2021 · Cells
- Macrophage Gal/GalNAc lectin 2 (MGL2)+ peritoneal antigen presenting cells during Fasciola hepatica infection are essential for regulatory T cell inductionMonique Costa, Valeria da Costa, Pablo Lores, Mercedes Landeira, Santiago A. Rodríguez-Zraquia, María Florencia Festari, Teresa Freire · 2022 · Scientific Reports
- Acquisition of Immune Privilege in GBM Tumors: Role of Prostaglandins and Bile SaltsMartyn A. Sharpe, David S. Baskin, Ryan D. Johnson, Alexandra M. Baskin · 2023 · International Journal of Molecular Sciences
- In situ conversion of defective Treg into SuperTreg cells to treat advanced IPEX-like disorders in miceYongqin Li, Yuxin Chen, Shaoshuai Mao, Ravinder Kumar Kaundal, Zhengyu Jing, Qin Chen, Xinxin Wang, Jing Xia, Dahai Liu, Jianlong Sun et al. · 2020 · Nature Communications
- Separating the wheat from the chaff: Making sense of Treg heterogeneity for better adoptive cellular therapyRianne Opstelten, Derk Amsen · 2021 · Immunology Letters
- Insights into the roles of IL-10–producing regulatory B cells in cardiovascular disorders: recent advances and future perspectivesHuiqin Zheng, Pei Cao, Zhaoliang Su, Lin Xia · 2023 · Journal of Leukocyte Biology
- The adaptability of regulatory T cells and Foxp3Shohei Hori, Ryuichi Murakami · 2021 · International Immunology
- Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasisLorena Carla Oliveira da Costa, Luiz Gustavo Gardinassi, Flavio Protasio Veras, Cristiane Milanezi, Leandra Náira Zambelli Ramalho, Luciana Benevides, José Carlos Alves-Filho, João S. Silva, Cacilda da Silva Souza · 2022 · Archives of Dermatological Research
- Loss of the FOXP1 Transcription Factor Leads to Deregulation of B Lymphocyte Development and Function at Multiple StagesJoseph D. Dekker, Gisele V. Baracho, Zilu Zhu, Gregory C. Ippolito, Robert J. Schmitz, Robert C. Rickert, Haley O. Tucker · 2019 · ImmunoHorizons
- Transcriptional Control of Regulatory T Cells in Cancer: Toward Therapeutic Targeting?Pierre Stéphan, Raphaëlle Lautraite, Allison Voisin, Yenkel Grinberg‐Bleyer · 2020 · Cancers
- NFATc1/αA and Blimp-1 Support the Follicular and Effector Phenotype of TregsAnika Koenig, Martin Vaeth, Yin Xiao, Cristina Maria Chiarolla, Raghu Erapaneedi, Matthias Klein, Lena Dietz, Nadine Hundhausen, Snigdha Majumder, Felix Schuessler et al. · 2021 · Frontiers in Immunology
- Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2Mayumi Saito, Aarthi Rajesh, Carrie Innes, Rachael van der Griend, Peter Fitzgerald, Bryony J. Simcock, Peter H. Sykes, Merilyn H. Hibma · 2022 · Journal of Cancer Research and Clinical Oncology
- Distinct Injury Responsive Regulatory T Cells Identified by Multi-Dimensional PhenotypingFei Guo, Brandon L. Hancock, Alec M. Griffith, Hui Lin, Kaitlyn Howard, Joshua Keegan, Fan Zhang, Adam T. Chicoine, Laura A. Cahill, Julie Ng et al. · 2022 · Frontiers in Immunology
- CD103 Regulates Dermal Regulatory T Cell Motility and Interactions with CD11c-Expressing Leukocytes to Control Skin InflammationM Ursula Norman, Zachary Chow, Pam Hall, Anne Cao Le, Kim Maree O’Sullivan, Sarah L. Snelgrove, James A. Deane, Michael J. Hickey · 2023 · The Journal of Immunology
- Regulatory T cells characterized by low Id3 expression are highly suppressive and accumulate during chronic infectionKatharina S. Rauch, Miriam Hils, Alexandra J. Menner, Mikael Sigvardsson, Susana Minguet, Peter Aichele, Kristina Schachtrup, Kristina Schachtrup · 2017 · Oncotarget
- Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potentialRoosa Kattelus, Inna Starskaia, Markus Lindén, Kedar Batkulwar, Sami Pietilä, Robert Moulder, Alexander Marson, Omid Rasool, Tomi Suomi, Laura L. Elo et al. · 2024 · Cellular and Molecular Life Sciences
- Transcription Factor Blimp-1: A Central Regulator of Oxidative Stress and Metabolic Reprogramming in Chronic Inflammatory DiseasesAline Yen Ling Wang, Ana Elena Aviña, Yen‐Yu Liu, Yun‐Ching Chang, Huang‐Kai Kao · 2025 · Antioxidants
- BLIMP1 negatively regulates IL-2 signaling in T cellsSuyasha Roy, Min Ren, Peng Li, Kairong Cui, Yaqiang Cao, Bryan A. Fisk, Tovah E. Markowitz, Neelam R. Redekar, Keiko Sakamoto, Keisuke Nagao et al. · 2025 · Science Advances
- The Dual Role of Interleukin-10 in Sepsis: Research Progress and Therapeutic ProspectsXianwen Wang, Qihang Huang, Jinwei Dai, Lina Zhang, Zhaoxin Qian · 2026 · Inflammation
- Lineage origin and transcriptional control of autoantigen-specific T-regulatory type 1 cellsEdgar Angelats, Pere Santamaría · 2023 · Frontiers in Immunology
- Characterization of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 4 regulated by heat shock factor 1 during heat stress in response to antiviral immunityChai Foong Lai, Ting‐Yu Wang, Min-I Yeh, Tzong-Yueh Chen · 2020 · Fish & Shellfish Immunology
- RNA Sequencing of the Pituitary Gland and Association Analyses Reveal PRKG2 as a Candidate Gene for Growth and Carcass Traits in Chinese Ningdu Yellow ChickensXinwei Xiong, Min Zhou, Xuenong Zhu, Yuwen Tan, Zhangfeng Wang, Jishang Gong, Jiguo Xu, Yafang Wen, Jian‐Xiang Liu, Xutang Tu et al. · 2022 · Frontiers in Veterinary Science
- A subpopulation of CD103posICOSpos Treg cells occurs at high frequency in lymphopenic mice and represents a lymph node specific differentiation stageThomas Barthlott, Angela J. T. Bosch, Caroline Maria Berkemeier, Rubén Nogales‐Cadenas, Lukas T. Jeker, Marcel P. Keller, A. Pascual-Montano, Georg A. Holländer · 2015 · European Journal of Immunology
- Host T Cell Dedifferentiation Effects Drive HIV-1 Latency StabilityAlexander G. Dalecki, Braxton D. Greer, Alexandra Emilie Duverger, Elan L. Strange, Eric Carlin, Frederic Wagner, Bi Shi, Kelsey Elizabeth Lowman, Mildred D. Perez, Christopher Tidwell et al. · 2022 · Journal of Virology
- B lymphocyte–induced maturation protein 1 (Blimp-1), a negative regulator of TH9 development, orchestrates the resolution of airway inflammation in patients with allergic asthmaSusetta Finotto · 2018 · Journal of Allergy and Clinical Immunology
- Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetesKuang-Ji Zhou, Shan-Jie Rong, Yue-Chen Liu, Fangxia Sun, Ting Wang, Qi-Lin Yu, Cong-Yi Wang · 2026 · Frontiers in Endocrinology
- BLIMP-1-dependent differentiation of T follicular helper cells into Foxp3+ T regulatory type 1 cellsJosep Garnica, Jun Yamanouchi, Robert C. Clarke, Joel Moro, Shari Thiessen, Javier Antônio Benevides Montaño, Debajyoti Mondal, Pau Serra, Pere Santamaría · 2025 · Frontiers in Immunology
- Vps34-orchestrated lipid signaling processes regulate the transitional heterogeneity and functional adaptation of effector regulatory T cellsErienne Grace Norton, Nicole M. Chapman, Hao Shi, Xiaoxi Meng, Hongling Huang, Anil KC, Sherri L. Rankin, Jordy Saravia, Sujing Yuan, Haoran Hu et al. · 2025 · PLoS Biology
- The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodesBongiwe Mahlobo, Faatima Laher, Werner Smidt, Funsho J. Ogunshola, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Thandekile Ngubane, Krista L. Dong, Ismail Jajbhay et al. · 2022 · BMC Immunology
- Rebooting Regulatory T Cell and Dendritic Cell Function in Immune-Mediated Inflammatory Diseases: Biomarker and Therapy Discovery under a Multi-Omics LensDimitra Kerdidani, Nikos E. Papaioannou, Evangelia Nakou, Themis Alissafi · 2022 · Biomedicines
- Foxp3+ regulatory T cells in the central nervous system and other nonlymphoid tissuesThomas Korn · 2023 · European Journal of Immunology
- Blimp-1 signaling pathways in T lymphocytes is essential to control the Trypanosoma cruzi infection-induced inflammationLuciana Benevides, Laís Amorim Sacramento, Franciele Pioto, Gabriel Dessotti Barretto, Vanessa Carregaro, João S. Silva · 2023 · Frontiers in Immunology
- Selective targeting or reprogramming of intra-tumoral TregsKeywan Mortezaee · 2024 · Medical Oncology
- Transcriptional and hormonal control of adipose Treg heterogeneity and functionAxel Kallies, Ajithkumar Vasanthakumar · 2024 · Immunological Reviews
- Regulation of Germinal Center Reactions by B and T CellsYoung Kim, Xindong Liu, Shinya Tanaka, Dat Q. Tran, Yeonseok Chung · 2013 · Antibodies
- Beyond FoxP3—Identification of a Chicken Regulatory T Cell SignatureIsabell Naumann, Edward S. Ricemeyer, Daniel Elleder, Jiřı́ Plachý, Dominik von La Roche, Kim Vučinić, Thomas Göbel, Bernd Kaspers, Simon P. Früh, Sonja Härtle · 2025 · European Journal of Immunology
- CD38 endows local antigen-specific Treg cells with stress resilience for control of compartmentalized CNS inflammationHsin-Hsiang Chen, Sofia Tyystjärvi, Domingo Navarro, Ravi Kant, Tanja Groll, Ingrid Wagner, Helena Domínguez Moreno, Irene Bonafonte-Pardàs, Rupert Öllinger, Ali Maisam Afzali et al. · 2026 · Nature Immunology
- UVB Irradiation Expands Skin-Resident CD81+Foxp3+ Regulatory T Cells with a Highly Activated PhenotypeHiroaki Shime, Mizuyu Odanaka, Masaki Imai, Daisuke Sugiyama, Shoryu Takayama, Akimichi Morita, Sayuri Yamazaki · 2024 · Journal of Investigative Dermatology
- The distinctive signature of regulatory CD4 T cells committed in the human thymusAlexandre A. S. F. Raposo, Susana Paço, Miguel Ângelo‐Dias, Pedro Rosmaninho, Afonso R. M. Almeida, Ana E. Sousa · 2025 · Frontiers in Immunology
- BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal AllergensAmanda Contreras, Darin L. Wiesner, Brock A. Kingstad-Bakke, Woojong Lee, John P. Svaren, Bruce S. Klein, M. Suresh · 2022 · Journal of Immunology Research
- CD4+ Regulatory T Cells in Human Cancer: Subsets, Origin, and Molecular RegulationJulian Swatler, Marco De Luca, Ivano Rotella, Veronica Lise, Emilia Maria Cristina Mazza, Enrico Lugli · 2024 · Cancer Immunology Research
- CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor MicroenvironmentD. Chung, Noor Shakfa, Jehan Vakharia, K. Warner, N. Jacquelot, A. Sayad, SeongJun Han, M. Ghaedi, Carlos R. Garcia-Batres, Jules Sotty et al. · 2025 · Cancer immunology research
- Prognostic Biomarkers for Hodgkin LymphomaMartin Sebastian Staege, Stefanie Kewitz, Toralf Bernig, Caspar D. Kühnöl, Christine Mauz‐Körholz · 2015 · Pediatric Hematology and Oncology
- Role of IRF4-Mediated Inflammation: Implication in Neurodegenerative DiseasesLiu F · 2017 · Neurology & Neurotherapy Open Access Journal
- Adipose tissue regulatory T cells: differentiation and functionAllen N. Fooks, Lisa Y. Beppu, Adolfo B. Frias, Louise M. D’Cruz · 2022 · International Reviews of Immunology
- Common and Exclusive Features of Intestinal Intraepithelial γδ T Cells and Other γδ T Cell SubsetsApostol K Apostolov, Miriame Hamani, Héctor Hernández‐Vargas, Ramdane Igalouzene, Alexandre Guyennon, Olivier Fesneau, Julien C. Marie, Saïdi M. Soudja · 2022 · ImmunoHorizons
- Programmed T cell differentiation: Implications for transplantationRebecca L. Crepeau, Mandy L. Ford · 2020 · Cellular Immunology
- Editorial: Survive to Fight: Effector Treg Cells in Systemic Lupus ErythematosusAntonio La Cava · 2016 · Arthritis & Rheumatology
- Adipose Treg cells in charge of metabolismMelanie Grusdat, Dirk Brenner · 2024 · Nature Immunology
- T-regulatory cells require Sin3a for stable expression of Foxp3Lanette M. Christensen, Tatiana Akimova, Liqing Wang, Rongxiang Han, Arabinda Samanta, Eros Di Giorgio, Wayne W. Hancock · 2024 · Frontiers in Immunology
- Control of Asthma and Allergy by Regulatory T CellsMin-Jhen Jheng, Hirohito Kita · 2024 · International Archives of Allergy and Immunology
- Tregs epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunityTyler R. Colson, James J. Cameron, Hayley I. Muendlein, Mei-An Nolan, Jamie L. Leiriao, James H. Kim, Alexander N. Poltorak, Xudong Joshua Li · 2025 · JCI Insight
- Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiationRyuichi Murakami, Norihito Hayatsu, Takahisa Miyao, Zhenan Liu, Yukito Kino, Shumpei Shibata, Suzu Kawagoe, Masashi Matsuda, Yusuke Iizuka, Hiroki Sugishita et al. · 2026 · Immunity
- Harnessing autoimmunity with dominant self-peptide: Modulating the sustainability of tissue-preferential antigen-specific Tregs by governing the binding stability via peptide flanking residuesYouwei Lin, Shun Sakuraba, Chandirasegaran Massilamany, Jayagopala Reddy, Yoshimasa Tanaka, Sachiko Miyake, Takashi Yamamura · 2023 · Journal of Autoimmunity
- The Increased Frequency of Type 1 Regulatory T (Tr1) Cells and the Altered Expression of Aryl Hydrocarbon Receptor (AHR) and Interferon Regulatory Factor-4 (IRF4) Genes in Type 1 Diabetes: A Case-Control StudyMohammed Sameir, Narjes Soleimanifar, Sara Assadiasl, Nihad Abdallah Selman, Maryam Sadr, Hanieh Mojtahedi, Ali Jaffer Mohammed, Rasha Hamzah Abdulhussein, Zahraa M Hamid Al-Gawwam, Safin Hassan Hussein et al. · 2024 · Cureus
- Transcription factor Bach2 balances tolerance and immunityAxel Kallies, Ajithkumar Vasanthakumar · 2013 · Immunology and Cell Biology
- Differentiation, regulation and function of regulatory T cells in non-lymphoid tissues and tumorsHongbo Ni, Yinghan Chen · 2023 · International Immunopharmacology
- The functional adaptation of effector Foxp3+ regulatory T cells to pulmonary inflammationFernando Alvarez, Ciriaco A. Piccirillo · 2023 · European Journal of Immunology
- An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfectionJonathan L. M. Fontes, Ricardo Khouri, Luís Gustavo Cavalcante Reinaldo, Erina M. A. Hassegawa, Antônio José Meneses Filho, Caroline Vilas Boas de Melo, Pablo Ivan Pereira Ramos, Rafael de Deus Moura, Carla Pagliari, Marta Santos et al. · 2024 · PLoS neglected tropical diseases
- An overview of the human immune system and the role of interferon regulatory factors (IRFs)Ashwinder Kaur, Chee-Mun Fang · 2020 · Progress In Microbes & Molecular Biology
- Conserved human effector Treg signature is reflected in transcriptomic and epigenetic landscapeGerdien Mijnheer, Lisanne Lutter, Michal Mokrý, Marlot van der Wal, Veerle Fleskens, Rianne C. Scholman, Aridaman Pandit, Weiyang Tao, Mark Wekking, Stephin J. Vervoort et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- PRDM1 Drives Human Primary T Cell Hyporesponsiveness by Altering the T Cell Transcriptome and EpigenomeHuidong Guo, Ming Wang, Bixia Wang, Liping Guo, Yifei Cheng, Zhidong Wang, Yuqian Sun, Yu Wang, Ying‐Jun Chang, Xiao‐Jun Huang · 2021 · SSRN Electronic Journal
- Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in miceLeonie Caroline Voß, Constantin Schmidt, Aenne Harberts, Michael Spohn, Peter Bradtke, Alina Borchers, Stefanie Fertig, Joanna Schmid, Friedrich Koch‐Nolte, Christian F. Krebs et al. · 2025 · Frontiers in Immunology