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A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage
Abstract
Mucosal-associated invariant T cells (MAIT cells) detect microbial vitamin B2 derivatives presented by the antigen-presenting molecule MR1. Here we defined three developmental stages and checkpoints for the MAIT cell lineage in humans and mice. Stage 1 and stage 2 MAIT cells predominated in thymus, while stage 3 cells progressively increased in abundance extrathymically. Transition through each checkpoint was regulated by MR1, whereas the final checkpoint that generated mature functional MAIT cells was controlled by multiple factors, including the transcription factor PLZF and microbial colonization. Furthermore, stage 3 MAIT cell populations were expanded in mice deficient in the antigen-presenting molecule CD1d, suggestive of a niche shared by MAIT cells and natural killer T cells (NKT cells). Accordingly, this study maps the developmental pathway and checkpoints that control the generation of functional MAIT cells.
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“The development and maturation of MAIT cells are dependent on microbiota, as demonstrated by reduced numbers of MAIT cells in GF mice, which can be restored through microbial colonization.”
From Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases (2024) · cites this paper as [691]
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“A comparison of mice housed in conventional specific-pathogen-free (SPF) conditions to germ-free (GF) animals confirmed previous observations that the microbiota is necessary for the presence of MAIT cells in the thymus, spleen, and gut (17, 18), and extended this requirement for MAIT cells in the skin, lungs, and liver (Fig. 1B).”
From MAIT cells are imprinted by the microbiota in early life and promote tissue repair (2019) · cites this paper as [18]
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The nuclear RNase III Drosha initiates microRNA processing
Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Rådmark, O., Kim, S., et al. (2003) · Nature · doi:10.1038/nature01957 · Cited by 5,299
MR1 presents microbial vitamin B metabolites to MAIT cells
Kjer-Nielsen, L., Patel, O., Corbett, A. J., Le Nours, J., Meehan, B., Liu, L., Bhati, M., Chen, Z., Kostenko, L., Reantragoon, R., et al. (2012) · Nature · doi:10.1038/nature11605 · Cited by 1,351
Self-citationSelection of evolutionarily conserved mucosal-associated invariant T cells by MR1
Treiner, E., Duban, L., Bahram, S., Radosavljevic, M., Wanner, V., Tilloy, F., Affaticati, P., Gilfillan, S., & Lantz, O. (2003) · Nature · doi:10.1038/nature01433 · Cited by 1,139
Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro
Schmitt, T. M., & Zúñiga-Pflücker, J. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00474-0 · Cited by 1,120
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Dusséaux, M., Martin, E., Serriari, N., Péguillet, I., Prémel, V., Louis, D., Milder, M., Bourhis, L. L., Soudais, C., Treiner, E., et al. (2010) · Blood · doi:10.1182/blood-2010-08-303339 · Cited by 1,045
Levy, M., Thaiss, C. A., Zeevi, D., Dohnalová, L., Zilberman-Schapira, G., Mahdi, J. A., David, E., Savidor, A., Korem, T., Herzig, Y., et al. (2015) · Cell · doi:10.1016/j.cell.2015.10.048 · Cited by 960
Antimicrobial activity of mucosal-associated invariant T cells
Bourhis, L. L., Martin, E., Péguillet, I., Guihot, A., Froux, N., Coré, M., Lévy, E., Dusséaux, M., Meyssonnier, V., Prémel, V., et al. (2010) · Nature Immunology · doi:10.1038/ni.1890 · Cited by 941
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
Corbett, A. J., Eckle, S. B. G., Birkinshaw, R. W., Liu, L., Patel, O., Mahony, J., Chen, Z., Reantragoon, R., Meehan, B. S., Cao, H., et al. (2014) · Nature · doi:10.1038/nature13160 · Cited by 876
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Savage, A., Constantinides, M. G., Han, J., Picard, D., Martin, E., Li, B.-F., Lantz, O., & Bendelac, A. (2008) · Immunity · doi:10.1016/j.immuni.2008.07.011 · Cited by 750
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Laubreton, D., Grau, M., Malassigné, V., Prieux, M., Tomkowiak, M., Vocanson, M., Walzer, T., & Marvel, J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.10.627689 · Cited by 1
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Jin, T., Liu, M., Yang, Z., Yang, Y., Zhao, D., Cheng, Q., Fu, S., Li, Y., Liu, G., Zhao, C., et al. (2023) · doi:10.22541/au.168680176.64802686/v1
Li, M., Jin, H., Wei, L., Zhang, T., Huang, S., Sun, G., Zhang, J., Jia, J., Li, C., Zhang, D., et al. (2023) · Current Medicine · doi:10.1007/s44194-023-00026-1
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Metadata
- Authors
- Koay, H.-F., Gherardin, N. A., Enders, A., Loh, L., Mackay, L. K., Almeida, C. F., Russ, B. E., Nold-Petry, C. A., Nold, M. F., Bedoui, S., Chen, Z., Corbett, A. J., Eckle, S. B. G., Meehan, B., d'Udekem, Y., Konstantinov, I. E., Lappas, M., Liu, L., Goodnow, C. C., Fairlie, D. P., Rossjohn, J., Chong, M. M., Kedzierska, K., Berzins, S. P., Belz, G. T., McCluskey, J., Uldrich, A. P., Godfrey, D. I., & Pellicci, D. G.
- Affiliations
- The University of Melbourne (AU)
- Hudson Institute of Medical Research (AU)
- Royal Children's Hospital (AU)
- The University of Queensland (AU)
- Monash University (AU)
- St Vincents Institute of Medical Research (AU)
- Federation University (AU)
- Corresponding author
- Godfrey, Dale I
- Pellicci, Daniel G
- ORCID
- Koay, Hui-Fern
- Gherardin, Nicholas A
- Enders, Anselm
- Loh, Liyen
- Mackay, Laura K
- Almeida, Catarina F
- Russ, Brendan E
- Nold, Marcel F
- Bedoui, Sammy
- Chen, Zhenjun
- Corbett, Alexandra J
- Eckle, Sidonia B G
- Meehan, Bronwyn
- Konstantinov, Igor E
- Lappas, Martha
- Liu, Ligong
- Goodnow, Chris C
- Fairlie, David P
- Rossjohn, Jamie
- Chong, Mark M
- Kedzierska, Katherine
- Berzins, Stuart P
- Belz, Gabrielle T
- McCluskey, James
- Uldrich, Adam P
- Godfrey, Dale I
- Pellicci, Daniel G
- Venue
- Nature Immunology
- Published
- 2016-09-26
- Volume
- 17
- Issue
- 11
- Pages
- 1300-1311
- ISSN
- 1529-2908 (ISSN-L)
- 1529-2916
- OpenAlex
- W2526319073
- Cited by
- 377
- References
- 44
- Citations by year
- 2026: 26 · 2025: 36 · 2024: 36 · 2023: 36 · 2022: 44 · 2021: 40 · 2020: 52 · 2019: 40 · 2018: 39 · 2017: 25 · 2016: 3
- FWCI
- 21.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Immunology (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (acceptedVersion)
- ANU Open Research (Australian National University) (submittedVersion)
- FedUni ResearchOnline (Federation University Australia) (submittedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- Funders
- National Heart Foundation of Australia
- Medical Research Council
- Australian Research Council (FT140100278, LE110100106)
- National Health and Medical Research Council (1054431, 1047025, 1013667, 1035858, 1106004, 1027369, CE140100011, 1023294, 1020770, 1083942, 1016629)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Keywords
- mucosal-associated invariant T cells, thymus development, MR1, PLZF, microbial colonization, CD1d, NKT cells, developmental checkpoints
- MeSH terms
- Mucosal-Associated Invariant T Cells, Animals, Cell Differentiation, Gene Expression Regulation, Humans, Male, Thymus Gland, Biomarkers, Immunophenotyping, Mice, Knockout, Gene Expression Profiling, MicroRNAs, Mice, Lymphoid Progenitor Cells, Antigens, CD1d
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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