Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

Liu, Jian, Divoux, Adeline, Sun, Jiusong, Zhang, Jie, Clément, Karine, Glickman, Jonathan N, Sukhova, Galina K, Wolters, Paul J +8 more·2009·Nature Medicine
DOI 10.1038/nm.1994

Cited by (795)

Items 601–700 of 795

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  2. Role of the Immune System in Obesity-Associated Inflammation and Insulin Resistance
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  3. The B-side story in insulin resistance
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  13. Immune Response and Oxidative Stress in Obesity-Induced Cancer
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  14. Recent updates on the influence of iron and magnesium on vascular, renal, and adipose inflammation and possible consequences for hypertension
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  16. Histologie du tissu adipeux blanc normal et pathologique
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  17. Mast cell, a new player in type 2 diabetes
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  18. Chemokine receptors on the defensive – the surprising role of CXCR4 in brown adipose tissue
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  20. Dietary deoxynucleic acid induces type 2 T-helper immune response through toll-like receptor 9 in mice
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    Sabah Hussein Khorsheed, Intisar F. Mustafa, Nazar Ahmed Naji · 2016 · Kirkuk University Journal-Scientific Studies
  24. Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry
    Suzan Wetzels, Mitchell Bijnen, Erwin Wijnands, Erik A.L. Biessen, Casper G. Schalkwijk, Kristiaan Wouters · 2018 · Journal of Visualized Experiments
  25. The effect of fluvastatin on mast cell function: genotype dependence
    Elizabeth Motunrayo Kolawole · 2014 · VCU Scholars Compass (Virginia Commonwealth University)
  26. Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE-activated mast cells
    Gianni García‐Faroldi, Elin Rönnberg, Mirjana Grujić, Gunnar Pejler · 2017 · Immunity Inflammation and Disease
  27. Strain-specific Differences in the Effects of Lymphocytes on the Development of Insulin Resistance and Obesity in Mice.
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  28. Manifestations of Adipose Tissue Dysfunction
    Nicola I. Abate, Anne E. Sumner, Manisha Chandalia · 2013 · Journal of Obesity
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    Courtney Lehman, Ray Stokes Peebles · 2025
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    Yiming Shao, Ke Song, Ruixin Yu, Xiao He, Chunmei Li, Yuling Deng, Yuan Zhang, Yixing Ren · 2025 · International Journal of Molecular Medicine
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    Wan-Ying Lu, Shan-Jie Rong, Shiwei Liu, Chunliang Yang, Yue-Chen Liu, Heba Al-Siddiqi, Fei Sun, Cong-Yi Wang · 2025 · Nutrition Reviews
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    Peter Mancuso · 2012 · Humana Press eBooks
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    ZHIHUA WANG, Qingyong Zhang, Wei Ping Zhu, Jianping Tao, Wei Meng · 2013 · International Journal of Molecular Medicine
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    Yong L. Zhao · 2014 · Elsevier eBooks
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  65. The mast cell: Another master in adipoimmunology
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  66. [An analysis of skin prick test reactivity to dust mite in overweight and normal weight children with allergic asthma before and after specific immunotherapy].
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  67. Ovarian mast cells migrate toward ovary-fimbria connection in neonatal MRL/MpJ mice
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    Daniela Strodthoff · 2013 · Figshare
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