NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

Hecker, Louise, Vittal, Ragini, Jones, Tamara, Jagirdar, Rajesh, Luckhardt, Tracy R, Horowitz, Jeffrey C, Pennathur, Subramaniam, Martinez, Fernando J +1 more·2009·Nature Medicine

Cited by (857)

Items 201–300 of 857

  1. Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis
    Shibnath Ghatak, Vincent Hascall, Roger R. Markwald, Carol A. Feghali‐Bostwick, Carol M. Artlett, Monika Beck Gooz, Galina S. Bogatkevich, Ilia Atanelishvili, Richard M. Silver, Jeanette Marjorie Wood et al. · 2017 · Journal of Biological Chemistry
  2. Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis
    Ye Cui, Jennifer V. Robertson, Shyam S. Maharaj, Lisa Waldhauser, Jianzhao Niu, Jifeng Wang, László Farkas, Martin R.J. Kolb, Jack Gauldie · 2011 · The International Journal of Biochemistry & Cell Biology
  3. Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis
    Hongmei Gu, Amanda Jo Fisher, Elizabeth A. Mickler, Frank Duerson, Oscar W. Cummings, Marc L. Peters-Golden, Homer L. Twigg, Trent M. Woodruff, David S. Wilkes, Ragini Vittal · 2016 · The FASEB Journal
  4. H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases
    Ildikó Szántó, Marc Philippe Pusztaszeri, Maria Mavromati · 2019 · Antioxidants
  5. Influences of innate immunity, autophagy, and fibroblast activation in the pathogenesis of lung fibrosis
    David N. O’Dwyer, Shanna L. Ashley, Bethany B. Moore · 2016 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  6. Redox mechanisms in age-related lung fibrosis
    Ashish Kurundkar, Victor John Thannickal · 2016 · Redox Biology
  7. Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm
    Francesc Jiménez‐Altayó, Thayna Meirelles, Eva Crosas‐Molist, Maria Alba Sorolla, Darya Gorbenko del Blanco, Judit López‐Luque, Aleksandra Mas‐Stachurska, Ana-Maria Siegert, Fabio Bonorino, Laura Barberà et al. · 2018 · Free Radical Biology and Medicine
  8. Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
    Anissa Anindya Widjaja, Jinrui Dong, Eleonora Adami, Sivakumar Viswanathan, Benjamin Ng, Leroy Sivappiragasam Pakkiri, Sonia Pankaj Chothani, Brijesh Kumar Singh, Wei‐Wen Lim, Jin Zhou et al. · 2021 · Science Translational Medicine
  9. Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions
    Craige, Siobhan M., Kant, Shashi, Reif, Michaella, Chen, Kai, Pei, Yongmei, Angoff, Rebecca, Sugamura, Koichi, Fitzgibbons, Timothy, Keaney, John F. · 2015 · Free Radical Biology and Medicine
  10. Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma
    Jinah Choi, Nicole Leanne Bidaud Corder, Bhargav Koduru, Yiyan Wang · 2014 · Free Radical Biology and Medicine
  11. A molecular basis for the anti‐inflammatory and anti‐fibrosis properties of cannabidiol
    Falone Sunda, Afolake Arowolo · 2020 · The FASEB Journal
  12. IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis
    Ragini Vittal, Lin Fan, Daniel S. Greenspan, Elizabeth A. Mickler, Bagavathi Gopalakrishnan, Hongmei Gu, Heather L. Benson, Chen Zhang, William J. Burlingham, Oscar W. Cummings et al. · 2012 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  13. Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.
    Deborah E. Citrin, Pataje G.S. Prasanna, Amanda J. Walker, Michael L. Freeman, Iris Eke, Mary Helen Barcellos‐Hoff, Molykutty J. Arankalayil, Eric P. Cohen, Ruth C. Wilkins, Mansoor M. Ahmed et al. · 2017 · Radiation Research
  14. MicroRNA regulatory networks in idiopathic pulmonary fibrosis
    Kusum V. Pandit, Jadranka Milošević · 2015 · Biochemistry and Cell Biology
  15. The matricellular protein CCN1 enhances TGF‐β1/SMAD3‐dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury
    Ashish Kurundkar, Deepali Kurundkar, Sunad Rangarajan, Morgan L. Locy, Yong Zhou, Rui-Ming Liu, Jaroslaw W. Zmijewski, Victor John Thannickal · 2016 · The FASEB Journal
  16. Myofibroblasts in the Infarct Area: Concepts and Challenges
    Evangelos P. Daskalopoulos, Ben J. Janssen, W. Matthijs Blankesteijn · 2012 · Microscopy and Microanalysis
  17. Tobacco Smoke–Induced Lung Fibrosis and Emphysema
    Danielle Morse, Iván O. Rosas · 2013 · Annual Review of Physiology
  18. Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity
    Y Li, Sarah Mouche, Tatjana Sajic, Christelle Veyrat‐Durebex, R Supale, Dominique D. Pierroz, Serge Ferrari, Francesco Negro, Ursula Hasler, Eric Féraille et al. · 2012 · International Journal of Obesity
  19. Nox Family NADPH Oxidases in Mechano-Transduction: Mechanisms and Consequences
    Ralf Peter Brandes, Norbert Weißmann, Katrin Schröder · 2013 · Antioxidants and Redox Signaling
  20. Oxidative Stress and Skin Fibrosis
    Anjali Shroff, Andrew Mamalis, Jared R. Jagdeo · 2014 · Current Pathobiology Reports
  21. TGF-beta signaling in cancer radiotherapy
    Juan Wang, Zhonghang Xu, Zhe Wang, Guoqiang Du, Limin Lun · 2021 · Cytokine
  22. Emerging role of immune cells as drivers of pulmonary fibrosis
    Steven Eugene Mutsaers, Tylah Miles, Cecilia M. Prêle, Gerard F. Hoyne · 2023 · Pharmacology & Therapeutics
  23. ROS homeostasis in cell fate, pathophysiology, and therapeutic interventions
    Yuan-Shen Chen, Huixiang Tian, Ding‐Chao Rong, Luozixian Wang, Shan Chen, Jun Zeng, Heng Xu, Jie Mei, Lei-Yun Wang, Yu‐Ligh Liou et al. · 2025 · Molecular Biomedicine
  24. Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis
    Jörg H. W. Distler, Carol A. Feghali‐Bostwick, Alina Soare, Yoshihide Asano, Oliver Distler, David Abraham · 2016 · Arthritis & Rheumatology
  25. Galectin-1 Accelerates Wound Healing by Regulating the Neuropilin-1/Smad3/NOX4 Pathway and ROS Production in Myofibroblasts
    Yueh‐Te Lin, Jhih-Sian Chen, Ming–Heng Wu, I‐Shan Hsieh, Chen-Hsien Liang, Cheng‐Lung Hsu, Tse-Ming Hong, Yuh‐Ling Chen · 2014 · Journal of Investigative Dermatology
  26. Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual nox4/nox1 inhibitors
    Gaggini, Francesca, Laleu, Benoît, Orchard, Mike, Fioraso-Cartier, Laetitia, Cagnon, Laurène, Houngninou-Molango, Sophie, Gradia, Angelo, Duboux, Guillaume, Merlot, Cédric, Heitz, Freddy et al. · 2011 · Bioorganic & Medicinal Chemistry
  27. The Role of Nrf2 in Pulmonary Fibrosis: Molecular Mechanisms and Treatment Approaches
    Yu Wang, Juan Wei, Huimin Deng, Li Zheng, Hao Yu Yang, Xin Lv · 2022 · Antioxidants
  28. Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence
    Yan Y. Sanders, Hui Liu, Gang Liu, Victor John Thannickal · 2014 · Free Radical Biology and Medicine
  29. Cytokines in chronic respiratory diseases
    Sergei P. Atamas, Svetlana P. Chapoval, Achsah Dorsey Keegan · 2013 · F1000 Biology Reports
  30. Nox4 modulates collagen production stimulated by transforming growth factor β1 in vivo and in vitro
    Elsa C. Chan, Hitesh Peshavariya, Guei‐Sheung Liu, Fan Jiang, Shiang Yong Lim, Gregory James Dusting · 2012 · Biochemical and Biophysical Research Communications
  31. Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis
    Ragini Vittal, Elizabeth A. Mickler, Amanda Jo Fisher, Chen Zhang, Katia Rothhaar, Hongmei Gu, Krista M. Brown, Amir Emtiazdjoo, Jeremy M. Lott, Sarah B. Frye et al. · 2013 · PLoS ONE
  32. Pleural Mesothelial Cell Differentiation and Invasion in Fibrogenic Lung Injury
    Jason S. Zolak, RAJESH M. JAGIRDAR, Ranu Surolia, Suman Karki, Octavio M. Oliva, Thomas Hock, Purushotham Guroji, Qiang Ding, Riu-Ming Liu, Subhashini Bolisetty et al. · 2013 · American Journal Of Pathology
  33. Cysteamine Modulates Oxidative Stress and Blocks Myofibroblast Activity in CKD
    Daryl M. Okamura, Nadia M. Bahrami, Shuyu Ren, Katie Pasichnyk, Juliana M. Williams, Jon A. Gangoiti, Jesús M. López-Guisa, Ikuyo Yamaguchi, Bruce A. Barshop, Jeremy S. Duffield et al. · 2013 · Journal of the American Society of Nephrology
  34. Mitochondria in Structural and Functional Cardiac Remodeling
    Natalia Torrealba, Pablo Aránguiz, Camila Alonso, Beverly A. Rothermel, Sergio Lavandero · 2017 · Advances in experimental medicine and biology
  35. Decoding NADPH oxidase 4 expression in human tumors
    Jennifer L. Meitzler, Hala R. Makhlouf, Smitha Antony, Yongzhong Wu, Donna O. Butcher, Guojian Jiang, Agnes N. Juhasz, Jiamo Lu, Iris M. Dahan, Pidder Jansen‐Dürr et al. · 2017 · Redox Biology
  36. Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts
    Razdan, Neetu, Vasilopoulos, Themistoklis, Herbig, Utz · 2018 · Aging Cell
  37. New Insights into the Role of Oxidative Stress in Scleroderma Fibrosis
    Armando Gabrielli, Silvia Svegliati, Gianluca Moroncini, Donatella Amico · 2012 · The Open Rheumatology Journal
  38. Activation of ENaC in collecting duct cells by prorenin and its receptor PRR: involvement of Nox4-derived hydrogen peroxide
    Xiaohan Lu, Fei Wang, Mi Liu, Kevin Yang, Adam Nau, Donald E. Kohan, Van R. Reese, Russell S. Richardson, Tianxin Yang · 2015 · American Journal of Physiology-Renal Physiology
  39. Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches – Pulmonary Disease/Asthma
    Camille Audousset, Toby K. McGovern, James G. Martin · 2021 · Frontiers in Physiology
  40. Pathophysiology of gadolinium-associated systemic fibrosis
    Brent Wagner, Viktor R. Drel, Yves C. Gorin · 2016 · American Journal of Physiology-Renal Physiology
  41. Reactive Oxygen and Nitrogen Species in the Development of Pulmonary Hypertension
    David J. Fulton, Xueyi Li, Zsuzsanna Bordán, Stephen B. Haigh, Austin Bentley, Feng Chen, Scott A. Barman · 2017 · Antioxidants
  42. ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling
    Kai Yazaki, Yosuke Matsuno, Kazufumi Yoshida, MINGMA THSERING SHERPA, Masayuki Nakajima, Masashi Matsuyama, Takumi Kiwamoto, Yuko Morishima, Yukio Ishii, Nobuyuki Hizawa · 2021 · European Journal of Cell Biology
  43. Oxygen‐Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF‐κB Pathways
    Chencheng Feng, Yang Zhang, Minghui Yang, Minghong Lan, Huan Liu, Bo Sheng Huang, Yue Zhou · 2017 · Oxidative Medicine and Cellular Longevity
  44. WNT Signaling in Lung Aging and Disease
    Mareike Lehmann, Hoeke Abele Baarsma, Mélanie Königshoff · 2016 · Annals of the American Thoracic Society
  45. Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice
    Yan Y. Sanders, Xing Lyv, Q. Jennifer Zhou, Zheyi Xiang, Denise D. Stanford, Sandeep Bodduluri, Steven Mark Rowe, Victor John Thannickal · 2020 · JCI Insight
  46. Alveolar epithelial disintegrity in pulmonary fibrosis
    Tejaswini Kulkarni, João A. de Andrade, Yong Zhou, Tracy Luckhardt, Victor John Thannickal · 2016 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  47. NADPH oxidases in bone homeostasis and osteoporosis
    Katrin Schröder · 2014 · Cellular and Molecular Life Sciences
  48. Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate
    Audrey Dooley, X. Shiwen, N. Aden, Thomas Henry Tranah, N. Desai, Christopher Paul Denton, David Abraham, Richard K. Bruckdorfer · 2010 · Lara D. Veeken
  49. Dermal delivery of HSP47 siRNA with NOX4-modulating mesoporous silica-based nanoparticles for treating fibrosis
    Jingga Morry, Worapol Ngamcherdtrakul, Shenda Gu, Shaun M. Goodyear, David J. Castro, Moataz M. Reda, Thanapon Sangvanich, Wassana Yantasee · 2015 · Biomaterials
  50. NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis
    Chao He, Jennifer L. Larson‐Casey, Dana Davis, Vidya Sagar Hanumanthu, Ana Leda F. Longhini, Victor John Thannickal, Linlin Gu, A. Brent Carter · 2019 · JCI Insight
  51. CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging
    Huachun Cui, Na Xie, Sami Banerjee, Tapan Dey, Rui-Ming Liu, Veena B. Antony, Yan Y. Sanders, Taylor Sterling Adams, José L. Gómez, Victor John Thannickal et al. · 2022 · American Journal of Respiratory and Critical Care Medicine
  52. Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosis
    Bruno Crestani, Valérie Besnard, Jorge Boczkowski · 2011 · The International Journal of Biochemistry & Cell Biology
  53. Oxidative stress, endogenous antioxidants, alcohol, and hepatitis C: pathogenic interactions and therapeutic considerations
    Jinah Choi · 2012 · Free Radical Biology and Medicine
  54. Integrin β 1: A Mechanosignaling Sensor Essential for Connective Tissue Deposition by Fibroblasts
    Andrew Leask · 2013 · Advances in Wound Care
  55. Lung extracellular matrix and redox regulation
    Walter H. Watson, Jeffrey D. Ritzenthaler, Jesse Roman · 2016 · Redox Biology
  56. Protective effects of liquiritin apioside on cigarette smoke‐induced lung epithelial cell injury
    Yan Guan, Fenfen Li, Ling Hong, Xiaofeng Yan, Gong‐Li Tan, HE Jun-shan, Xinwei Dong, Mengjing Bao, Qiang-min Xie · 2011 · Fundamental and Clinical Pharmacology
  57. Reactive oxygen species: Are they important for haematopoiesis?
    José Luis Sardina, Guillermo López-Ruano, Beatriz Sánchez-Sánchez, Marcial Llanillo, Ángel Hernández‐Hernández · 2011 · Critical Reviews in Oncology/Hematology
  58. The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop
    G. R. Scott Budinger, Ronald A. Kohanski, Weiniu Gan, Michael Steffen Kobor, Luı́s A. Nunes Amaral, Mary Y. Armanios, Karl T. Kelsey, Annie Pardo, Rubin M. Tuder, Fernando Macián et al. · 2017 · The Journals of Gerontology Series A
  59. NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
    Ashok Kumar Jayavelu, Jörg P. Müller, Reinhard Bauer, S-A Böhmer, J Lässig, Sabine Cerny‐Reiterer, Wolfgang R. Sperr, Peter Valent, Barbara Maurer, Richard Moriggl et al. · 2015 · Leukemia
  60. NADPH oxidases: Pathophysiology and therapeutic potential in age-associated pulmonary fibrosis
    Kosuke Kato, Louise Hecker · 2020 · Redox Biology
  61. Genome-wide analysis of DNA methylation and gene expression defines molecular characteristics of Crohn’s disease-associated fibrosis
    Tammy M. Sadler, Jeffrey Bhasin, Yaomin Xu, Jill Barnholz-Sloan, Yanwen Chen, Angela H. Ting, Eleni Stylianou · 2016 · Clinical Epigenetics
  62. Nuclear Factor–Erythroid-2–Related Factor 2 in Aging and Lung Fibrosis
    Shobha Swamy, Namakkal Soorappan Rajasekaran, Victor John Thannickal · 2016 · American Journal Of Pathology
  63. Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis
    Jarrod Wesley Barnes, Dawn Duncan, Scott Helton, Samuel B. Hutcheson, Deepali Kurundkar, Naomi J. Logsdon, Morgan L. Locy, Jaleesa M. Garth, Rebecca S. Denson, Carol F. Farver et al. · 2019 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  64. NOX enzymes: potential target for the treatment of acute lung injury
    Stéphanie Carnésecchi, Jean‐Claude Pache, Constance Barazzone‐Argiroffo · 2012 · Cellular and Molecular Life Sciences
  65. NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme
    Chia‐Hung Hsieh, Chung‐Pu Wu, Hsu‐Tung Lee, Ji‐An Liang, Chun-Yen Yu, Yu‐Jung Lin · 2012 · Free Radical Biology and Medicine
  66. Epigenetics in lung fibrosis
    Britney A. Helling, Ivana V. Yang · 2015 · Current Opinion in Pulmonary Medicine
  67. Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous Fibrosis
    Ila Pant, Somanahalli Girish Rao, Paturu Kondaiah · 2016 · Scientific Reports
  68. Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator‐Induced Lung Injury
    Sashko Gregoriev Spassov, Rosa Donus, Paul Mikael Ihle, Helen Engelstaedter, Alexander Hoetzel, Simone Faller · 2017 · Oxidative Medicine and Cellular Longevity
  69. <scp>Pre‐clinical</scp> evidence of a dual <scp>NADPH</scp> oxidase 1/4 inhibitor (setanaxib) in liver, kidney and lung fibrosis
    Thannickal, Victor J., Jandeleit‐Dahm, Karin, Szyndralewiez, Cédric, Török, Natalie J. · 2023 · Journal of Cellular and Molecular Medicine
  70. Targeting Histone Deacetylases in Idiopathic Pulmonary Fibrosis: A Future Therapeutic Option
    Martina Korfei, Poornima Mahavadi, Andreas Guenther · 2022 · Cells
  71. Backstage players of fibrosis: NOX4, mTOR, HDAC, and S1P; companions of TGF-β
    Alexis Paulina Jiménez‐Uribe, Tania Gómez‐Sierra, Omar Emiliano Aparicio‐Trejo, Marisol Orozco‐Ibarra, José Pedraza‐Chaverrí · 2021 · Cellular Signalling
  72. The lung mesenchyme in development, regeneration, and fibrosis
    Elie El Agha, Victor John Thannickal · 2023 · Journal of Clinical Investigation
  73. Oxidative Stress in Pulmonary Fibrosis
    Eva Otoupalova, Sam Smith, Guangjie Cheng, Victor John Thannickal · 2020 · Comprehensive physiology
  74. A Reactive Oxygen Species–Mediated Loop Maintains Increased Expression of NADPH Oxidases 2 and 4 in Skin Fibroblasts From Patients With Systemic Sclerosis
    Tatiana Spadoni, Silvia Svegliati, Donatella Amico, Lisa Albani, Gianluca Moroncini, Enrico Vittorio Avvedimento, Armando Gabrielli · 2015 · Arthritis & Rheumatology
  75. New insight into the Nox4 subcellular localization in HEK293 cells: First monoclonal antibodies against Nox4
    Leilei Zhang, Minh Vu Chuong Nguyen, Bernard Lardy, Algirdas J. Jesaitis, Alexeï Grichine, Francis Rousset, Monique Talbot, Marie‐Hélène Paclet, Guanxiang Qian, Françoise Morel · 2010 · Biochimie
  76. Transforming growth factor type beta (TGF-β) requires reactive oxygen species to induce skeletal muscle atrophy
    Johanna Ábrigo, Juan Carlos Aristizábal Rivera, Felipe Simón, Daniel Cabrera, Claudio Cabello‐Verrugio · 2016 · Cellular Signalling
  77. Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis
    Lin An, Liying Peng, Ning-Yuan Sun, Yilin Yang, Xiaowei Zhang, Bin Li, Baolin Liu, Ping Li, Jun Chen · 2018 · Antioxidants and Redox Signaling
  78. Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization
    Linlin Gu, Jennifer L. Larson‐Casey, A. Brent Carter · 2017 · The FASEB Journal
  79. Interstitial lung disease and diabetes
    Venkat Rajasurya, Kulothungan Gunasekaran, Salim Surani · 2020 · World Journal of Diabetes
  80. Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling
    Zhiheng Sun, Zhihua Ji, Huiwen Meng, Wanyu He, Bin Li, Xiaoyue Pan, Yanlin Zhou, Guoying Yu · 2024 · Journal of Translational Medicine
  81. New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis
    Qiang Ding, Tracy Luckhardt, Louise Hecker, Yong Zhou, Gang Liu, Veena B. Antony, Joao A. deAndrade, Victor John Thannickal · 2011 · Drugs
  82. NADPH oxidase DUOX1 sustains TGF-β1 signalling and promotes lung fibrosis
    Ruy A. N. Louzada, Raphaël Corre, Rabii Ameziane El Hassani, Lydia Meziani, Madeleine Jaillet, Aurélie Cazes, Bruno Crestani, Éric Deutsch, Corinne Dupuy · 2020 · European Respiratory Journal
  83. Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target
    Sonsoles Piera-Velázquez, Sergio A. Jiménez · 2021 · Journal of Clinical Medicine
  84. Oxidative stress and antioxidants in interstitial lung disease
    Aalt Bast, Antje R. Weseler, Guido R.M.M. Haenen, Gertjan J.M. den Hartog · 2010 · Current Opinion in Pulmonary Medicine
  85. Therapeutic pro-fibrogenic signaling pathways in fibroblasts
    Stefania Cannito, Erica Novo, Maurizio Parola · 2017 · Advanced Drug Delivery Reviews
  86. Promotion of oxidative stress is associated with mitochondrial dysfunction and muscle atrophy in aging mice
    Tomoyasu Kadoguchi, Kazunori Shimada, Tetsuro Miyazaki, Kenichi Kitamura, Mitsuhiro Kunimoto, Tatsuro Aikawa, Yurina Sugita, Shohei Ouchi, Tomoyuki Shiozawa, Miho Yokoyama‐Nishitani et al. · 2019 · Geriatrics and gerontology international/Geriatrics & gerontology international
  87. Idiopathic Pulmonary Fibrosis: Pathobiology of Novel Approaches to Treatment
    Toby M. Maher · 2011 · Clinics in Chest Medicine
  88. Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD
    Javier Milara, Teresa Peiró, Adela Serrano, Ricardo Guijarro, Cristóbal Zaragozá, Herman Tenor, Julio Cortijo · 2014 · Pulmonary Pharmacology & Therapeutics
  89. Therapeutic Targeting of Redox Signaling in Myofibroblast Differentiation and Age-Related Fibrotic Disease
    Natalie Sampson, Peter Berger, Christoph Zenzmaier · 2012 · Oxidative Medicine and Cellular Longevity
  90. NRF2 deficiency reduces life span of mice administered thoracic irradiation
    Elizabeth L. Travis, Girish Rachakonda, Xinhui Zhou, Katrina E. Korhonen, Konjeti R. Sekhar, Swati Biswas, Michael L. Freeman · 2011 · Free Radical Biology and Medicine
  91. Right‐side and left‐side colon cancer follow different pathways to relapse
    Kerry M. Bauer, Amanda B. Hummon, Steven Allen Buechler · 2011 · Molecular Carcinogenesis
  92. Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo
    Fayong Luo, Yan Zhuang, Mark D Sides, Cecilia G. Sanchez, Bin Shan, Eric S. White, Joseph A. Lasky · 2014 · Respiratory Research
  93. Thermodynamic Aspects and Reprogramming Cellular Energy Metabolism during the Fibrosis Process
    Alexandre Vallée, Yves Lecarpentier, Jean-Noël Vallée · 2017 · International Journal of Molecular Sciences
  94. Molecular Activation of the NLRP3 Inflammasome in Fibrosis: Common Threads Linking Divergent Fibrogenic Diseases
    Carol M. Artlett, James D. Thacker · 2014 · Antioxidants and Redox Signaling
  95. Macrophage‐specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1 / MMP ‐9 pathways
    Candice Trocmé, Christine Deffert, Julien Cachat, Yves R. A. Donati, Christelle Tissot, Sylvie Papacatzis, Vincent Braunersreuther, Jean‐Claude Pache, Karl‐Heinz Krause, Rikard Holmdahl et al. · 2014 · The Journal of Pathology
  96. The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice
    Agnes W. Boots, Carmen Veith, Catrin Albrecht, Roger Bartholomé, Marie-José Drittij-Reijnders, Sandra M.H. Claessen, Aalt Bast, Martin Rosenbruch, Leonie Jonkers, Frederik‐Jan van Schooten et al. · 2020 · BMC Pulmonary Medicine
  97. Trans-Plasma Membrane Electron Transport in Mammals: Functional Significance in Health and Disease
    Domenico Del Principe, Luciana Avigliano, Isabella Savini, Maria Valeria Catani · 2010 · Antioxidants and Redox Signaling
  98. Inhibition of NADPH Oxidases Prevents Chronic Ethanol-Induced Bone Loss in Female Rats
    Jin‐Ran Chen, Oxana P. Lazarenko, Kartik Shankar, Michael L. Blackburn, Charles K. Lumpkin, Thomas M. Badger, Martin J. J. Ronis · 2010 · Journal of Pharmacology and Experimental Therapeutics
  99. Endothelial-to-mesenchymal transition in systemic sclerosis
    Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Marta Vomero, Luca Navarini, Vincenza Dolo, Paola Cipriani, Roberto Giacomelli · 2021 · Clinical & Experimental Immunology
  100. Development and Preclinical Efficacy of Novel Transforming Growth Factor-β1 Short Interfering RNAs for Pulmonary Fibrosis
    Corina N. D’Alessandro‐Gabazza, Tetsu Kobayashi, Daniel Boveda-Ruiz, Takehiro Takagi, Masaaki Toda, Paloma Gil-Bernabe, Yasushi Miyake, Atsushi Yasukawa, Yoshikazu Matsuda, 鈴木 昇 et al. · 2011 · American Journal of Respiratory Cell and Molecular Biology